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The map label for this gene is yusP [H]

Identifier: 91783978

GI number: 91783978

Start: 2890784

End: 2892400

Strand: Reverse

Name: yusP [H]

Synonym: Bxe_A1830

Alternate gene names: 91783978

Gene position: 2892400-2890784 (Counterclockwise)

Preceding gene: 91783979

Following gene: 91783977

Centisome position: 59.08

GC content: 64.5

Gene sequence:

>1617_bases
ATGAGCATTGCGCCGGGCAGCGTCCGCGAGGAAGAGAGCTCCGCCGGTCAGGGCATCAGGTCGTTCCGGCAGTCACTGCT
TGCGATGCTGGGGCTATCGAGCGTGGTCATGATGGTCGCGATCGACCAGACGGTGGTCGGTACGGCTTTGCCGTCTATCG
TCGCGGATCTGCATCGCTTCGATCTCTACGAGTGGGTCGCCACCTCCTACCTGCTGACGTCGGTGATTACCGTGCCGATT
TTCGGCCGGCTCGGAGACTGGCTGGGAAGAAAACCCCTGATCGTCATTGCGATCGTGCTCTTCACTGTTGCATCGGCGTT
GTGCGGTTTTGCGCAGACCATGCCCATGCTGATCGCCTGCCGCGCATTGCAGGGGATAGGCGGCGGCATGCTGGTCGGAA
CCTGCTTTGCCTCCATACCGGACCTCTTTCCGGATCCGGTGGTGCGGCTGCGCTGGCAGGTCCTGTTCTCGAGCGCCTTT
GGTCTGGCCAATGCCGTCGGGCCGTCGCTCGGCGGCTTTCTGAGCCAGCATTACGGGTGGCGCTCCGCCTTTCTCGTCAA
CATACCGGTGGGCGTTGTAAGCCTTTATCTCGCAGCGAAGCATCTGCCGCATATCCGGCATGCCAGGTTCGAGCGGTTGA
ACGCGGACTGGAAAGGAGCATGTCTGATTACCGTTGCGCTGGGCTCGCTTCAGCTCCTCGTCGAGGCGGCAGGTAGTACG
GGTTCCCATGCCGGCCTCTACGCGGCGGTGGCCGTGCTTTCGATGGGATTGCTGGTGCGGCAGGAGCGGCGCGCGCCCAA
TCCCGTCATTCCGCCCGGCTTGCTCAAGGATCGCGCGACCCTCGTGCTGCTCGTGCTGTCGCTGCTGATGGGCGTCGCGA
TGTTCGTGCTGCTCTTTTATGTGCCGCTGCTGTTGCAGGGCGGTCTGGGGCTCGACGCCGGCAAGGCTGGAATCGTCGTG
ACACCGATGGTCGTGTGCATCACGGTCGGCACCATTACCAACACGCGCATCGTGACTCGCCTGGAGAAGCCGAACCTCCT
GCTGTATCTCGGGTTTGGTCTTCTCGGCGTGTCCTGCGCGGCGATTGCTTCTGTCGGCGCCGGCGGTGCGAGCGTGGGGT
TCGTCGTCGCGATGGTGATGGCCGGCGTCGGTATCGGGTTTGTGATGCCGAACCTGACCGTGTTCGTGCAGCAGGTCGCC
GGAAAAACGCGCCTCGGCATTGCCACGGCGCTGATCCAGTCGGCACGGATGGTGGGCGGCATGCTGGGTACGGCGATGGC
GGGGACGATGGCGCGCCACCTGTATCGAGCAGGGCTCGAACCGGTGTTGACGGCGAAGGCAGCCGCAGCGCCCGGACATT
GGACCCTTGCGTTGCAGGACCCGCAAACGCTCATGTCGGCGCAGGCGGCAGCGGACTTCGCCGGGCACGCCAATCACGCC
GGCTTCGATGGCGAGGCAATGCTGGGGGCGGCGCGCGCGGTGCTCGTCCACGCGCTGCAAACGTCGCTCTTCGGGGTCGC
GCTGCTGATGGCCGCGGCGTGCGTGATTGTGCGGCTACTGCCGTTGATTCCGATTACCTCGATAGCGGCATCGAGGCAGC
AGGGCGCACCGGAATAA

Upstream 100 bases:

>100_bases
TAGGCATCGGGTTACAGGATATTGTTCTGGCGGGGATTGCATGGGAGAAGCACGTGAGTCGCAACATGATCAGATTGCGG
GGAGAGTTGCAGGGGCTGCA

Downstream 100 bases:

>100_bases
TGACTACGCCGACGGCCCGAAAGAGTGCGAGTGCACCGCGTCATTTCTGGCAATCAATGTACGCGGCTTCTCTGGCGACA
TGGATCGAAGCCGTCGCACA

Product: major facilitator superfamily drug efflux transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MSIAPGSVREEESSAGQGIRSFRQSLLAMLGLSSVVMMVAIDQTVVGTALPSIVADLHRFDLYEWVATSYLLTSVITVPI
FGRLGDWLGRKPLIVIAIVLFTVASALCGFAQTMPMLIACRALQGIGGGMLVGTCFASIPDLFPDPVVRLRWQVLFSSAF
GLANAVGPSLGGFLSQHYGWRSAFLVNIPVGVVSLYLAAKHLPHIRHARFERLNADWKGACLITVALGSLQLLVEAAGST
GSHAGLYAAVAVLSMGLLVRQERRAPNPVIPPGLLKDRATLVLLVLSLLMGVAMFVLLFYVPLLLQGGLGLDAGKAGIVV
TPMVVCITVGTITNTRIVTRLEKPNLLLYLGFGLLGVSCAAIASVGAGGASVGFVVAMVMAGVGIGFVMPNLTVFVQQVA
GKTRLGIATALIQSARMVGGMLGTAMAGTMARHLYRAGLEPVLTAKAAAAPGHWTLALQDPQTLMSAQAAADFAGHANHA
GFDGEAMLGAARAVLVHALQTSLFGVALLMAAACVIVRLLPLIPITSIAASRQQGAPE

Sequences:

>Translated_538_residues
MSIAPGSVREEESSAGQGIRSFRQSLLAMLGLSSVVMMVAIDQTVVGTALPSIVADLHRFDLYEWVATSYLLTSVITVPI
FGRLGDWLGRKPLIVIAIVLFTVASALCGFAQTMPMLIACRALQGIGGGMLVGTCFASIPDLFPDPVVRLRWQVLFSSAF
GLANAVGPSLGGFLSQHYGWRSAFLVNIPVGVVSLYLAAKHLPHIRHARFERLNADWKGACLITVALGSLQLLVEAAGST
GSHAGLYAAVAVLSMGLLVRQERRAPNPVIPPGLLKDRATLVLLVLSLLMGVAMFVLLFYVPLLLQGGLGLDAGKAGIVV
TPMVVCITVGTITNTRIVTRLEKPNLLLYLGFGLLGVSCAAIASVGAGGASVGFVVAMVMAGVGIGFVMPNLTVFVQQVA
GKTRLGIATALIQSARMVGGMLGTAMAGTMARHLYRAGLEPVLTAKAAAAPGHWTLALQDPQTLMSAQAAADFAGHANHA
GFDGEAMLGAARAVLVHALQTSLFGVALLMAAACVIVRLLPLIPITSIAASRQQGAPE
>Mature_537_residues
SIAPGSVREEESSAGQGIRSFRQSLLAMLGLSSVVMMVAIDQTVVGTALPSIVADLHRFDLYEWVATSYLLTSVITVPIF
GRLGDWLGRKPLIVIAIVLFTVASALCGFAQTMPMLIACRALQGIGGGMLVGTCFASIPDLFPDPVVRLRWQVLFSSAFG
LANAVGPSLGGFLSQHYGWRSAFLVNIPVGVVSLYLAAKHLPHIRHARFERLNADWKGACLITVALGSLQLLVEAAGSTG
SHAGLYAAVAVLSMGLLVRQERRAPNPVIPPGLLKDRATLVLLVLSLLMGVAMFVLLFYVPLLLQGGLGLDAGKAGIVVT
PMVVCITVGTITNTRIVTRLEKPNLLLYLGFGLLGVSCAAIASVGAGGASVGFVVAMVMAGVGIGFVMPNLTVFVQQVAG
KTRLGIATALIQSARMVGGMLGTAMAGTMARHLYRAGLEPVLTAKAAAAPGHWTLALQDPQTLMSAQAAADFAGHANHAG
FDGEAMLGAARAVLVHALQTSLFGVALLMAAACVIVRLLPLIPITSIAASRQQGAPE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1790195, Length=313, Percent_Identity=31.629392971246, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI87081983, Length=414, Percent_Identity=26.0869565217391, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789042, Length=427, Percent_Identity=27.1662763466042, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788710, Length=302, Percent_Identity=27.1523178807947, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788392, Length=384, Percent_Identity=29.4270833333333, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790146, Length=171, Percent_Identity=31.5789473684211, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319770, Length=384, Percent_Identity=26.8229166666667, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323735, Length=324, Percent_Identity=25.9259259259259, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322958, Length=473, Percent_Identity=23.8900634249471, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325455, Length=162, Percent_Identity=27.1604938271605, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321663, Length=150, Percent_Identity=30.6666666666667, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 55982; Mature: 55851

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SIAPGSVREEESSAGQGIRSFRQSLLAMLGLSSVVMMVAIDQTVVGTALPSIVADLHRF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLYEWVATSYLLTSVITVPIFGRLGDWLGRKPLIVIAIVLFTVASALCGFAQTMPMLIAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RALQGIGGGMLVGTCFASIPDLFPDPVVRLRWQVLFSSAFGLANAVGPSLGGFLSQHYGW
HHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
RSAFLVNIPVGVVSLYLAAKHLPHIRHARFERLNADWKGACLITVALGSLQLLVEAAGST
HHEEEEECCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHCCCC
GSHAGLYAAVAVLSMGLLVRQERRAPNPVIPPGLLKDRATLVLLVLSLLMGVAMFVLLFY
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPLLLQGGLGLDAGKAGIVVTPMVVCITVGTITNTRIVTRLEKPNLLLYLGFGLLGVSCA
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHEEEECCCCEEEEECHHHHHHHHH
AIASVGAGGASVGFVVAMVMAGVGIGFVMPNLTVFVQQVAGKTRLGIATALIQSARMVGG
HHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
MLGTAMAGTMARHLYRAGLEPVLTAKAAAAPGHWTLALQDPQTLMSAQAAADFAGHANHA
HHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCC
GFDGEAMLGAARAVLVHALQTSLFGVALLMAAACVIVRLLPLIPITSIAASRQQGAPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]