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The map label for this gene is adhA [H]

Identifier: 91783965

GI number: 91783965

Start: 2878185

End: 2879171

Strand: Reverse

Name: adhA [H]

Synonym: Bxe_A1844

Alternate gene names: 91783965

Gene position: 2879171-2878185 (Counterclockwise)

Preceding gene: 91783966

Following gene: 91783956

Centisome position: 58.81

GC content: 66.46

Gene sequence:

>987_bases
ATGCGTGCGATGGTGTTCGACGGTAGCTCAGCGTTGTTGCGTGAGCAGGAGGTGCCGGACCCGAAGCCCGGTCCCGGGCA
ACTGCTGATCCAGATTCACGCGTGCGGCGTGTGCCGCACCGATCTTCATCTGGTTGACCATGAGCTCGAGCATCCGAAGC
AGCCCGTGATTCCGGGCCACGAGATCGTCGGTACCGTGGCCGGGCTCGGCGCGGGTGTGACGGGCTTTGCCGTCGGCGAC
CGGGTGGGCGTGCCGTGGCTCGGCCACACCTGCGGGCATTGCCGCTACTGCCTGTCGGCGCGGGAAAATCTCTGCGACGA
ACCGGGCTTCACGGGCTATACGATCGACGGCGGTTACGCCGAGCGCACCGTCGCCGACAGTCAGTATTGCTTTCATCTGC
CGGCGCAGTACCCGGATATCGAGGCGGCGCCGTTGCTGTGCGCGGGTCTGATCGGCTACCGCACGTTGAAAATGGCGGGC
GACGCCCAGCGGATCGGCATTTACGGTTTTGGCGCGGCGGCGCATATCGTCGCGCAGGTCGCGCTTCATCAGAAGCGCAC
GGTGTATGCGTTCACGCGCCCGGGCGATCACGCGGCCCAGCAACTCGCGCTGCGCCTTGGCGCGGCGTGGGCGGGCGGCA
GCGACGAAGCGCCGCCCGCCGAGCTGGATGCAGCCCTGATCTTCGCACCCGTCGGAGCGCTCGTTCCGCAAGCATTGCGC
GCGGTGGCAAAAGGGGGGACGGTGGTGTGCGGCGGGATTCACATGAGCGACATTCCGTCATTCCCCTACGCATTTCTGTG
GGGCGAGCGGCGCGTGGTATCGATCGCCAATCTGACGCGCGAGGACGGACTTGCCTTCATGCGAATTGCTACCGAGCGGC
GCCTCGAGATCGACACGACCACTTACGCGCTGACGGATGCGAACCGGGCACTGAGCGATCTGCGGGATGGCAGGTTAACC
GGCGCCGCGGTGCTCGTAGTCCGGTAG

Upstream 100 bases:

>100_bases
GCCGGCAGGGCAGCCGGCGTGGGTCGCAGTATCGCGTCGCGATGCTTGCCGCGGCGGGACTTGATATGTACGCTGGCTTA
CCAGGTTTGAGGAGAACCGT

Downstream 100 bases:

>100_bases
TCCGGTAGTCCATTAGTTCGTTGGCCGTTTGGCGCGACGCGGCGCGCCATTCCGTTGCCGTGCGCTTCGCGCTGGCGCTA
CCTTCCGGCCCCGGCGAATC

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MRAMVFDGSSALLREQEVPDPKPGPGQLLIQIHACGVCRTDLHLVDHELEHPKQPVIPGHEIVGTVAGLGAGVTGFAVGD
RVGVPWLGHTCGHCRYCLSARENLCDEPGFTGYTIDGGYAERTVADSQYCFHLPAQYPDIEAAPLLCAGLIGYRTLKMAG
DAQRIGIYGFGAAAHIVAQVALHQKRTVYAFTRPGDHAAQQLALRLGAAWAGGSDEAPPAELDAALIFAPVGALVPQALR
AVAKGGTVVCGGIHMSDIPSFPYAFLWGERRVVSIANLTREDGLAFMRIATERRLEIDTTTYALTDANRALSDLRDGRLT
GAAVLVVR

Sequences:

>Translated_328_residues
MRAMVFDGSSALLREQEVPDPKPGPGQLLIQIHACGVCRTDLHLVDHELEHPKQPVIPGHEIVGTVAGLGAGVTGFAVGD
RVGVPWLGHTCGHCRYCLSARENLCDEPGFTGYTIDGGYAERTVADSQYCFHLPAQYPDIEAAPLLCAGLIGYRTLKMAG
DAQRIGIYGFGAAAHIVAQVALHQKRTVYAFTRPGDHAAQQLALRLGAAWAGGSDEAPPAELDAALIFAPVGALVPQALR
AVAKGGTVVCGGIHMSDIPSFPYAFLWGERRVVSIANLTREDGLAFMRIATERRLEIDTTTYALTDANRALSDLRDGRLT
GAAVLVVR
>Mature_328_residues
MRAMVFDGSSALLREQEVPDPKPGPGQLLIQIHACGVCRTDLHLVDHELEHPKQPVIPGHEIVGTVAGLGAGVTGFAVGD
RVGVPWLGHTCGHCRYCLSARENLCDEPGFTGYTIDGGYAERTVADSQYCFHLPAQYPDIEAAPLLCAGLIGYRTLKMAG
DAQRIGIYGFGAAAHIVAQVALHQKRTVYAFTRPGDHAAQQLALRLGAAWAGGSDEAPPAELDAALIFAPVGALVPQALR
AVAKGGTVVCGGIHMSDIPSFPYAFLWGERRVVSIANLTREDGLAFMRIATERRLEIDTTTYALTDANRALSDLRDGRLT
GAAVLVVR

Specific function: Preferred Specificity Is Towards 1-Propanol. [C]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71565152, Length=98, Percent_Identity=39.7959183673469, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4501933, Length=93, Percent_Identity=40.8602150537634, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87081918, Length=319, Percent_Identity=32.9153605015674, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082401, Length=324, Percent_Identity=29.0123456790123, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1786518, Length=217, Percent_Identity=35.0230414746544, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790045, Length=171, Percent_Identity=34.5029239766082, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787863, Length=230, Percent_Identity=25.2173913043478, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI226510992, Length=296, Percent_Identity=27.027027027027, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788073, Length=133, Percent_Identity=32.3308270676692, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082125, Length=142, Percent_Identity=31.6901408450704, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562584, Length=336, Percent_Identity=25.297619047619, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17562582, Length=340, Percent_Identity=27.3529411764706, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71988145, Length=328, Percent_Identity=23.4756097560976, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562876, Length=126, Percent_Identity=38.8888888888889, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562878, Length=126, Percent_Identity=37.3015873015873, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=159, Percent_Identity=39.622641509434, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324486, Length=159, Percent_Identity=37.1069182389937, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6319621, Length=210, Percent_Identity=35.2380952380952, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323729, Length=159, Percent_Identity=35.8490566037736, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319949, Length=201, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323980, Length=150, Percent_Identity=37.3333333333333, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319257, Length=205, Percent_Identity=30.2439024390244, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319258, Length=255, Percent_Identity=25.4901960784314, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737897, Length=152, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR014187
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 34928; Mature: 34928

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAMVFDGSSALLREQEVPDPKPGPGQLLIQIHACGVCRTDLHLVDHELEHPKQPVIPGH
CCEEEECCCHHHHHHCCCCCCCCCCCEEEEEEEECCEECHHHHHHHHHHCCCCCCCCCCH
EIVGTVAGLGAGVTGFAVGDRVGVPWLGHTCGHCRYCLSARENLCDEPGFTGYTIDGGYA
HHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCC
ERTVADSQYCFHLPAQYPDIEAAPLLCAGLIGYRTLKMAGDAQRIGIYGFGAAAHIVAQV
CCEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHEEECCCCEEEEEEECCHHHHHHHHH
ALHQKRTVYAFTRPGDHAAQQLALRLGAAWAGGSDEAPPAELDAALIFAPVGALVPQALR
HHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHCHHHEEHHHHHHHHHHHH
AVAKGGTVVCGGIHMSDIPSFPYAFLWGERRVVSIANLTREDGLAFMRIATERRLEIDTT
HHHCCCEEEECCCCCCCCCCCCEEEEECCCEEEEEHHHHHHCCEEEEEECCCCEEEECCE
TYALTDANRALSDLRDGRLTGAAVLVVR
EEEEECHHHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure
MRAMVFDGSSALLREQEVPDPKPGPGQLLIQIHACGVCRTDLHLVDHELEHPKQPVIPGH
CCEEEECCCHHHHHHCCCCCCCCCCCEEEEEEEECCEECHHHHHHHHHHCCCCCCCCCCH
EIVGTVAGLGAGVTGFAVGDRVGVPWLGHTCGHCRYCLSARENLCDEPGFTGYTIDGGYA
HHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCC
ERTVADSQYCFHLPAQYPDIEAAPLLCAGLIGYRTLKMAGDAQRIGIYGFGAAAHIVAQV
CCEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHEEECCCCEEEEEEECCHHHHHHHHH
ALHQKRTVYAFTRPGDHAAQQLALRLGAAWAGGSDEAPPAELDAALIFAPVGALVPQALR
HHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHCHHHEEHHHHHHHHHHHH
AVAKGGTVVCGGIHMSDIPSFPYAFLWGERRVVSIANLTREDGLAFMRIATERRLEIDTT
HHHCCCEEEECCCCCCCCCCCCEEEEECCCEEEEEHHHHHHCCEEEEEECCCCEEEECCE
TYALTDANRALSDLRDGRLTGAAVLVVR
EEEEECHHHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]