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The map label for this gene is atzB [H]

Identifier: 91783875

GI number: 91783875

Start: 2795077

End: 2796474

Strand: Reverse

Name: atzB [H]

Synonym: Bxe_A1936

Alternate gene names: 91783875

Gene position: 2796474-2795077 (Counterclockwise)

Preceding gene: 91783878

Following gene: 91783873

Centisome position: 57.12

GC content: 64.45

Gene sequence:

>1398_bases
ATGACGATGGAACAAACGGCCAATCGAACGAACAAGCCGAAGCAAACGATGCTGGTCAAGCATGCGGACGTGCTGGTCAC
GATGGACGGCGCCCGGCGCGAACTGCGCGACGGCGGCCTGTATATCGAGGACAACCGCATCGTCGCGGTCGGACCGACGG
CGCAATTGCCGCAAACGGCCGATGACGTGCTGGACCTGCGTGGCCACCTGGTGATTCCGGGTCTCGTGAACACGCACCAT
CACATGTATCAGAGCCTGACGCGCGCGATTCCCGCCGCGCAGAACGCCGAGTTGTTCGGCTGGCTGACGAGCCTCTACAA
GGTGTGGGCGAACCTCACGCCGGAGATGATCGAAATCTCGACGCTGACGGCAATGGCCGAACTGTTGCTGTCCGGCTGCA
CGACTTCGAGCGACCATTTGTATATCTATCCGAACGGCAGCCGGCTCGACGACAGCATCGCCGCGGCGCGCCGGATCGGC
ATGCGTTTTCACGCGGCGCGCGGCAGCATGAGCGTGGGGCAGAAAGACGGCGGCCTGCCGCCGGATTCGGTGGTCGAAAG
TGAAGCGGACATTCTGAAAGACACGCAGCGCCTGATCGAGACATACCACGACGAAGGCCGTTACGCGATGCTACGCGTGG
TGGTCGCGCCATGCTCGCCGTTCTCGGTGAGCCGCGATCTGATGCGCGAATCGGCGGTCATGGCGCGGCAGTACGGTGTG
TCGATGCATACGCACCTGGCGGAGAACGTCAACGACGTCGCATATAGCCGCGAGAAGTTCGGCATGACGCCGGCGCAGTA
TGCGCAAGACCTCGGCTGGGTCGGTCACGACGTGTGGCACGCGCACTGTGTGCAACTCGACGACGCGGGCATCGAACTGT
TCGCGCGCACCGGCACCGGCGTCGCGCATTGTCCGTGTTCGAACATGCGGCTCGCGTCGGGTATCGCGCCGGTCAGGCGC
ATGCGTCTGGCCGGTGTGCCGGTGGGTCTCGGCGTCGACGGTTCGGCGTCGAACGACGGCGCGCAGATGGTCGCCGAAGT
GCGCCAGGCTTTATTGCTGCAGCGAGTCGGCTTTGGTCCGGACGCGATGACCGCGCGCGAAGCATTGGAAATCGCCACGC
TCGGCGGCGCGAAGGTGCTCAATCGCGACGATATCGGCGCGCTGGCGCCGGGCATGGCGGCGGACTTCGTGTCGTTCGAT
TTGCGTCAGCCGCTGTTCGCGGGCGCTTTGCATGATCCGGTTGCGGCGCTCGTGTTCTGCGCGCCGTCACAGGTGAGCCA
CAGCGTGATCGGCGGCAAGGTGGTCGTGAAGGACGGGCAGTTGACGACGCTGGAGCTCGGACCGGTCATCGAGCAACACA
ACCGGTTGGCGAAGACGCTTTACGAAGCAGCGGCGTAA

Upstream 100 bases:

>100_bases
AACCGGGCCAACGGCGTTCTACGTGACGCGGCGGCACGGTGGCGTGCCGTCACATCGCGTTCGAACGGCTTTGCACGGAA
GCAATGAAGCGGAGAAACGA

Downstream 100 bases:

>100_bases
CGCGAGAGAGCAGGGTTATCGGTGATGAAACGCATCGCGCCGCCGATAACCCACATGAATGCGAAAACATTAAGGCTTGT
CGATCAACGTCCTGGTGGCT

Product: hydroxydechloroatrazine ethylaminohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTMEQTANRTNKPKQTMLVKHADVLVTMDGARRELRDGGLYIEDNRIVAVGPTAQLPQTADDVLDLRGHLVIPGLVNTHH
HMYQSLTRAIPAAQNAELFGWLTSLYKVWANLTPEMIEISTLTAMAELLLSGCTTSSDHLYIYPNGSRLDDSIAAARRIG
MRFHAARGSMSVGQKDGGLPPDSVVESEADILKDTQRLIETYHDEGRYAMLRVVVAPCSPFSVSRDLMRESAVMARQYGV
SMHTHLAENVNDVAYSREKFGMTPAQYAQDLGWVGHDVWHAHCVQLDDAGIELFARTGTGVAHCPCSNMRLASGIAPVRR
MRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALAPGMAADFVSFD
LRQPLFAGALHDPVAALVFCAPSQVSHSVIGGKVVVKDGQLTTLELGPVIEQHNRLAKTLYEAAA

Sequences:

>Translated_465_residues
MTMEQTANRTNKPKQTMLVKHADVLVTMDGARRELRDGGLYIEDNRIVAVGPTAQLPQTADDVLDLRGHLVIPGLVNTHH
HMYQSLTRAIPAAQNAELFGWLTSLYKVWANLTPEMIEISTLTAMAELLLSGCTTSSDHLYIYPNGSRLDDSIAAARRIG
MRFHAARGSMSVGQKDGGLPPDSVVESEADILKDTQRLIETYHDEGRYAMLRVVVAPCSPFSVSRDLMRESAVMARQYGV
SMHTHLAENVNDVAYSREKFGMTPAQYAQDLGWVGHDVWHAHCVQLDDAGIELFARTGTGVAHCPCSNMRLASGIAPVRR
MRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALAPGMAADFVSFD
LRQPLFAGALHDPVAALVFCAPSQVSHSVIGGKVVVKDGQLTTLELGPVIEQHNRLAKTLYEAAA
>Mature_464_residues
TMEQTANRTNKPKQTMLVKHADVLVTMDGARRELRDGGLYIEDNRIVAVGPTAQLPQTADDVLDLRGHLVIPGLVNTHHH
MYQSLTRAIPAAQNAELFGWLTSLYKVWANLTPEMIEISTLTAMAELLLSGCTTSSDHLYIYPNGSRLDDSIAAARRIGM
RFHAARGSMSVGQKDGGLPPDSVVESEADILKDTQRLIETYHDEGRYAMLRVVVAPCSPFSVSRDLMRESAVMARQYGVS
MHTHLAENVNDVAYSREKFGMTPAQYAQDLGWVGHDVWHAHCVQLDDAGIELFARTGTGVAHCPCSNMRLASGIAPVRRM
RLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALAPGMAADFVSFDL
RQPLFAGALHDPVAALVFCAPSQVSHSVIGGKVVVKDGQLTTLELGPVIEQHNRLAKTLYEAAA

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=381, Percent_Identity=24.4094488188976, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1789249, Length=396, Percent_Identity=29.2929292929293, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI87082177, Length=441, Percent_Identity=23.8095238095238, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17540282, Length=420, Percent_Identity=22.1428571428571, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6319963, Length=344, Percent_Identity=25, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24643849, Length=355, Percent_Identity=25.3521126760563, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 50208; Mature: 50077

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMEQTANRTNKPKQTMLVKHADVLVTMDGARRELRDGGLYIEDNRIVAVGPTAQLPQTA
CCCCHHCCCCCCCHHHHEEEECCEEEEECCHHHHHHCCCEEEECCEEEEECCCCCCCCCH
DDVLDLRGHLVIPGLVNTHHHMYQSLTRAIPAAQNAELFGWLTSLYKVWANLTPEMIEIS
HHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
TLTAMAELLLSGCTTSSDHLYIYPNGSRLDDSIAAARRIGMRFHAARGSMSVGQKDGGLP
HHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCC
PDSVVESEADILKDTQRLIETYHDEGRYAMLRVVVAPCSPFSVSRDLMRESAVMARQYGV
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCC
SMHTHLAENVNDVAYSREKFGMTPAQYAQDLGWVGHDVWHAHCVQLDDAGIELFARTGTG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHEEEECCCCEEEEEECCCC
VAHCPCSNMRLASGIAPVRRMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGP
EEECCCCCCCHHHCHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
DAMTAREALEIATLGGAKVLNRDDIGALAPGMAADFVSFDLRQPLFAGALHDPVAALVFC
CHHHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHC
APSQVSHSVIGGKVVVKDGQLTTLELGPVIEQHNRLAKTLYEAAA
CCCHHHHHHCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMEQTANRTNKPKQTMLVKHADVLVTMDGARRELRDGGLYIEDNRIVAVGPTAQLPQTA
CCCHHCCCCCCCHHHHEEEECCEEEEECCHHHHHHCCCEEEECCEEEEECCCCCCCCCH
DDVLDLRGHLVIPGLVNTHHHMYQSLTRAIPAAQNAELFGWLTSLYKVWANLTPEMIEIS
HHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
TLTAMAELLLSGCTTSSDHLYIYPNGSRLDDSIAAARRIGMRFHAARGSMSVGQKDGGLP
HHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCCC
PDSVVESEADILKDTQRLIETYHDEGRYAMLRVVVAPCSPFSVSRDLMRESAVMARQYGV
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCC
SMHTHLAENVNDVAYSREKFGMTPAQYAQDLGWVGHDVWHAHCVQLDDAGIELFARTGTG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHEEEECCCCEEEEEECCCC
VAHCPCSNMRLASGIAPVRRMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGP
EEECCCCCCCHHHCHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
DAMTAREALEIATLGGAKVLNRDDIGALAPGMAADFVSFDLRQPLFAGALHDPVAALVFC
CHHHHHHHHHHHCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHC
APSQVSHSVIGGKVVVKDGQLTTLELGPVIEQHNRLAKTLYEAAA
CCCHHHHHHCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]