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The map label for this gene is tsr [H]

Identifier: 91783789

GI number: 91783789

Start: 2690395

End: 2692011

Strand: Reverse

Name: tsr [H]

Synonym: Bxe_A2023

Alternate gene names: 91783789

Gene position: 2692011-2690395 (Counterclockwise)

Preceding gene: 91783790

Following gene: 91783788

Centisome position: 54.99

GC content: 65.55

Gene sequence:

>1617_bases
ATGAGCCAGCGCGCAAAAACAGCCAGAGCGATCAAAACCACGATGACCAGGAACCTGACTATCAATCTACGGATCGCGAT
CACGATCGCGTTTCTCGGCGTGCTGCTGATTGCCACCGGCGCGCTCGGCATTCTCGGCATGAACCGGAGCAACGAGGCGC
AGCACGACGCGTACACGGTCCATTTCGCGTCGGTCGTCGCGCTCGGCAAATCAGGCACGGCCATGTCGCGGGCGCGTTTC
GGACTCGACTGGGCCATGAGCAATCCGCACTCGCCGCAACTGGCCGCGCAACTCGAGCGCGCCCGCATGCTGCTCGGCGA
TTCGGACAAATGGTGGAACGCCTTTCGCGATCTGCCGAAAACGCCCGAACTGCAGCGCCTCACCGACGACCTCGACGCGA
AGCGCACCGCCGTGCGCCGCGACGGCATCGACAAACTGATCGCGGCGATCCGCAGCGGCGACGCGAGCTGGATGGACGAA
AGCCGCGCGAATCATCTGATCGGCCTTTATACGGCGATGAACGCGAGCCAGGGTGCGCTGGAGAATTATCTGGACCAGCA
GGCGAGCGACGCGAACGAGCGCTCCGCCGCGCTTTTTCATACGCTGCTTTACGCGTGCATCGGCAGCATTCTGGTGGGGC
TGACGGTGGCGTTCATCAGCTGGCGCACGTTGCGCCGCGCGATCATGGCGCCGCTGAACGACGCGCTGCGCCAGTTCGAC
GCGATCGCCGCCGGCGAACTGACGACCCATGTGCCGATTCGTTCGAACGACGAAATGGCGACGCTGTTGCGCGGTGTCGC
GTCGATGCAGGACAAGCTTGGCGCGACCGTCACCACCGTGCGGGCCGGTTCGCATTCGATCGCATCGTCCACGCAGCAGA
TCGCCGCGGGCAATCTCGATCTGTCGCAACGCACCGAGGAACAGGCCGCGTCGCTCGAAGAAACCGCGGCGGCGATGGAG
CAGCTCACCTCCACCGTGCAACTGAATGCCGAGAACGCGCATCACGCGAGCGAGCTGGCCACGCGCGCGTCGGAAATGGC
CGCGCGCGGGCGCGATTCGGTGGGCAGCATGGTCGAGACCATGCGCGTGATCCACGCGGGTTCGTCGAAAATGACGGGCA
TCATTACCGCGATCGAAGGCATTGCGTTTCAGACCAATATCCTCGCGCTGAACGCGGCTGTCGAGGCGGCCCGCGCGGGC
GAAGAAGGGCGCGGCTTCGCGGTGGTGGCGGGCGAGGTGCGCAGTCTGGCGCAGCGTTCGGCGGCTGCTGCGAAAGAGAT
CGGCGCGCTGATCGCGGAGTCGACCTCGCGCGTGGAGAGCGGCGCGGGACTCGTCGACGAAGCGGGCGGCACGATGCAGG
AAATCGAAACCGCGATCGGGCGCGTGGCGCGTATCGTCGGCGAAATCGCGGCGGCCTCGAAAGAACAGAGCGAAGGCATC
AGACAGGTGAGCCTCGCCGTCACGCAGATGGACGAGGTCACGCAGCACAATGCGGCGCTGGTGGAAGAAAGCGCGGCGAC
CGCGAACTCGCTCGCGGACCAGGCTCGGCAATTGAGCGAGCTGACCGCGGCATTCAAAGTCGCGAGCGATGCGGCGCAGC
GCGAGGCCGCTTTCTGA

Upstream 100 bases:

>100_bases
TTCCATTTGTGGAACAAAATCGTTGAATCACAAAATCAAACTGGTCATGTGAAAGGCGTCGGGGACCCATCGCCTGTCAC
CGTGCGCGGGGCCGCACGTC

Downstream 100 bases:

>100_bases
ACTGTCCGCTTCTAAATCGTATTCACGCCGCGGCGTTCGCACAGGCGCCTTCCAGGCTGCCTTCGCGCAACGGTATCCGG
TAGCAGCCCGCTTGCGCAAC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MSQRAKTARAIKTTMTRNLTINLRIAITIAFLGVLLIATGALGILGMNRSNEAQHDAYTVHFASVVALGKSGTAMSRARF
GLDWAMSNPHSPQLAAQLERARMLLGDSDKWWNAFRDLPKTPELQRLTDDLDAKRTAVRRDGIDKLIAAIRSGDASWMDE
SRANHLIGLYTAMNASQGALENYLDQQASDANERSAALFHTLLYACIGSILVGLTVAFISWRTLRRAIMAPLNDALRQFD
AIAAGELTTHVPIRSNDEMATLLRGVASMQDKLGATVTTVRAGSHSIASSTQQIAAGNLDLSQRTEEQAASLEETAAAME
QLTSTVQLNAENAHHASELATRASEMAARGRDSVGSMVETMRVIHAGSSKMTGIITAIEGIAFQTNILALNAAVEAARAG
EEGRGFAVVAGEVRSLAQRSAAAAKEIGALIAESTSRVESGAGLVDEAGGTMQEIETAIGRVARIVGEIAAASKEQSEGI
RQVSLAVTQMDEVTQHNAALVEESAATANSLADQARQLSELTAAFKVASDAAQREAAF

Sequences:

>Translated_538_residues
MSQRAKTARAIKTTMTRNLTINLRIAITIAFLGVLLIATGALGILGMNRSNEAQHDAYTVHFASVVALGKSGTAMSRARF
GLDWAMSNPHSPQLAAQLERARMLLGDSDKWWNAFRDLPKTPELQRLTDDLDAKRTAVRRDGIDKLIAAIRSGDASWMDE
SRANHLIGLYTAMNASQGALENYLDQQASDANERSAALFHTLLYACIGSILVGLTVAFISWRTLRRAIMAPLNDALRQFD
AIAAGELTTHVPIRSNDEMATLLRGVASMQDKLGATVTTVRAGSHSIASSTQQIAAGNLDLSQRTEEQAASLEETAAAME
QLTSTVQLNAENAHHASELATRASEMAARGRDSVGSMVETMRVIHAGSSKMTGIITAIEGIAFQTNILALNAAVEAARAG
EEGRGFAVVAGEVRSLAQRSAAAAKEIGALIAESTSRVESGAGLVDEAGGTMQEIETAIGRVARIVGEIAAASKEQSEGI
RQVSLAVTQMDEVTQHNAALVEESAATANSLADQARQLSELTAAFKVASDAAQREAAF
>Mature_537_residues
SQRAKTARAIKTTMTRNLTINLRIAITIAFLGVLLIATGALGILGMNRSNEAQHDAYTVHFASVVALGKSGTAMSRARFG
LDWAMSNPHSPQLAAQLERARMLLGDSDKWWNAFRDLPKTPELQRLTDDLDAKRTAVRRDGIDKLIAAIRSGDASWMDES
RANHLIGLYTAMNASQGALENYLDQQASDANERSAALFHTLLYACIGSILVGLTVAFISWRTLRRAIMAPLNDALRQFDA
IAAGELTTHVPIRSNDEMATLLRGVASMQDKLGATVTTVRAGSHSIASSTQQIAAGNLDLSQRTEEQAASLEETAAAMEQ
LTSTVQLNAENAHHASELATRASEMAARGRDSVGSMVETMRVIHAGSSKMTGIITAIEGIAFQTNILALNAAVEAARAGE
EGRGFAVVAGEVRSLAQRSAAAAKEIGALIAESTSRVESGAGLVDEAGGTMQEIETAIGRVARIVGEIAAASKEQSEGIR
QVSLAVTQMDEVTQHNAALVEESAATANSLADQARQLSELTAAFKVASDAAQREAAF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=539, Percent_Identity=41.7439703153989, Blast_Score=309, Evalue=3e-85,
Organism=Escherichia coli, GI1787690, Length=434, Percent_Identity=44.4700460829493, Blast_Score=299, Evalue=3e-82,
Organism=Escherichia coli, GI1788195, Length=309, Percent_Identity=56.3106796116505, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1788194, Length=384, Percent_Identity=46.875, Blast_Score=288, Evalue=8e-79,
Organism=Escherichia coli, GI1789453, Length=329, Percent_Identity=34.6504559270517, Blast_Score=178, Evalue=7e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57078; Mature: 56947

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRAKTARAIKTTMTRNLTINLRIAITIAFLGVLLIATGALGILGMNRSNEAQHDAYTV
CCCHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHEE
HFASVVALGKSGTAMSRARFGLDWAMSNPHSPQLAAQLERARMLLGDSDKWWNAFRDLPK
HHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
TPELQRLTDDLDAKRTAVRRDGIDKLIAAIRSGDASWMDESRANHLIGLYTAMNASQGAL
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHCCCCEEEEHHHCCCCHHHH
ENYLDQQASDANERSAALFHTLLYACIGSILVGLTVAFISWRTLRRAIMAPLNDALRQFD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIAAGELTTHVPIRSNDEMATLLRGVASMQDKLGATVTTVRAGSHSIASSTQQIAAGNLD
HHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCC
LSQRTEEQAASLEETAAAMEQLTSTVQLNAENAHHASELATRASEMAARGRDSVGSMVET
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MRVIHAGSSKMTGIITAIEGIAFQTNILALNAAVEAARAGEEGRGFAVVAGEVRSLAQRS
HHHHHCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
AAAAKEIGALIAESTSRVESGAGLVDEAGGTMQEIETAIGRVARIVGEIAAASKEQSEGI
HHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RQVSLAVTQMDEVTQHNAALVEESAATANSLADQARQLSELTAAFKVASDAAQREAAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQRAKTARAIKTTMTRNLTINLRIAITIAFLGVLLIATGALGILGMNRSNEAQHDAYTV
CCHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHEE
HFASVVALGKSGTAMSRARFGLDWAMSNPHSPQLAAQLERARMLLGDSDKWWNAFRDLPK
HHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
TPELQRLTDDLDAKRTAVRRDGIDKLIAAIRSGDASWMDESRANHLIGLYTAMNASQGAL
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHCCCCEEEEHHHCCCCHHHH
ENYLDQQASDANERSAALFHTLLYACIGSILVGLTVAFISWRTLRRAIMAPLNDALRQFD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIAAGELTTHVPIRSNDEMATLLRGVASMQDKLGATVTTVRAGSHSIASSTQQIAAGNLD
HHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCC
LSQRTEEQAASLEETAAAMEQLTSTVQLNAENAHHASELATRASEMAARGRDSVGSMVET
HHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MRVIHAGSSKMTGIITAIEGIAFQTNILALNAAVEAARAGEEGRGFAVVAGEVRSLAQRS
HHHHHCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
AAAAKEIGALIAESTSRVESGAGLVDEAGGTMQEIETAIGRVARIVGEIAAASKEQSEGI
HHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
RQVSLAVTQMDEVTQHNAALVEESAATANSLADQARQLSELTAAFKVASDAAQREAAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]