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The map label for this gene is ilvA [H]

Identifier: 91783773

GI number: 91783773

Start: 2671133

End: 2672707

Strand: Reverse

Name: ilvA [H]

Synonym: Bxe_A2039

Alternate gene names: 91783773

Gene position: 2672707-2671133 (Counterclockwise)

Preceding gene: 91783774

Following gene: 91783772

Centisome position: 54.59

GC content: 63.75

Gene sequence:

>1575_bases
TTGTTGTTACACGAACTCAAACAGGCGGCCGAAGCCGCCGATAGCGTCGCGCTTCGTCACGACTACCTGAAGAAAACCCT
GACCGCGCGCGTCTACGACGTCGCCCGCGAGACCGAACTCGAACGCGCGCCGAATCTGTCTGCACGTCTGCGCAATCCGG
TCTACCTGAAGCGCGAGGACAACCAGCCGGTGTTCTCGTTCAAGGTGCGCGGCGCGTACAACAAGATGGCGCATATTCCG
GCCGAGGCGCTGGAACGCGGGGTGATTACGGCCTCGGCGGGCAATCATGCGCAGGGCGTCGCGCTGTCGGCCGCGCGCAT
GGGCGTGAAGGCGATCATCGTGGTGCCGGTCACCACGCCGCAGGTGAAGGTCGACGCGGTGCGCGCGCACGGCGGGCCGA
CCGTCGAAGTCGTGCAGTTCGGCGAATCGTACAGCGACGCGTATGGCCATGCGGTGAAACTGCAGGAAGAGCGCGACCTG
ACCTTCGTGCATCCGTTCGACGATCCGTACGTGATCGCCGGACAGGGCACGGTGGCAATGGAGATCCTGAGCCAGCACCA
GGGGCCTATTCACGCGATCTTCGTGCCGATCGGCGGCGGCGGACTCGCGGCAGGCGTGGCCGCGTATGTGAAATCGGTGC
GGCCCGAGATCAAGGTGATCGGCGTGCAGACCGATGATTCGTGCGCGATGGCCGCATCGCTGAAAGCCGGCGAGCGGGTC
ACGCTGAACGAAGTCGGCCTGTTCTCGGACGGCACGGCGGTGAAACTGGTCGGCGAAGAAACCTTCCGCCTCTGCCGCGA
ATATCTCGACGACGTGCTGCTCGTGGACACCGACGCGCTATGCGCCGCCATCAAGGACGTGTTCCAGGACACCCGCAGCG
TGCTGGAACCCGCCGGCTCGCTCGCGGTGGCCGGGGCGAAACAGTATGCGGAGCGCGAAGGCATCGAGAACCAGACGCTG
ATCGCGATCACATCGGGCGCGAACATGAACTTCGACCGCATGCGCTTCGTGGCCGAGCGCGCCGAAGTCGGCGAAGCGCG
TGAAGCCGTGTTCGCCGTGACGATCCCCGAAGAGCGCGGCAGTTTCCGGCGTTTCTGCGAACTGGTGGGCACGCGCAGCG
TCACCGAGTTCAACTACCGGATTGCGGACGCGAATTCCGCCCATATCTTCGTGGGCGTGCAGATCAGGAATCGCAGCGAA
TCCGCGCAGATCGCGGGGGCGTTCGAAGCGCACGGCTTCGCCACCGTCGATCTGACTTTCGACGAACTGTCCAAGCAGCA
CATCCGTTACATGGTAGGCGGCCGCTCGCCTCTGGCGCACGACGAACGGCTGTTCCGCTTCGAGTTTCCCGAACGTCCGG
GCGCGCTGATGAAATTCCTTTCGTCGATGGCGCCGAACTGGAATATCAGCCTGTTCCACTATCGCAACCAGGGCGCGGAC
TATAGCTCGATTCTGGTCGGCATCCAGGTGCCGGAGAGCGAGAATGCGGCGTTCGACCAGTTTCTCGCCACGCTCGGCTA
TCCGAACTGGGAAGAGACGCAGAATCCTGTTTATCGCCTGTTTCTCGCGTCGTAG

Upstream 100 bases:

>100_bases
ACACATAACCCGCCACCTGAGGCGGGTTTTTTTATGTCCGCTTGCAACCTGCCTCCTGTGAACTCTTTGTTGATTCGTCC
TTGCCGCACAGGAGCTTGCC

Downstream 100 bases:

>100_bases
AACGGCTCGGGGTTTACCTTGACCTTGCGCGACACGGCGCGAAGGATGAGCCGTCCGGCGGATGAGCCACGAGCCGTGCC
TGGACGGCGTTAGCACCCAG

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MLLHELKQAAEAADSVALRHDYLKKTLTARVYDVARETELERAPNLSARLRNPVYLKREDNQPVFSFKVRGAYNKMAHIP
AEALERGVITASAGNHAQGVALSAARMGVKAIIVVPVTTPQVKVDAVRAHGGPTVEVVQFGESYSDAYGHAVKLQEERDL
TFVHPFDDPYVIAGQGTVAMEILSQHQGPIHAIFVPIGGGGLAAGVAAYVKSVRPEIKVIGVQTDDSCAMAASLKAGERV
TLNEVGLFSDGTAVKLVGEETFRLCREYLDDVLLVDTDALCAAIKDVFQDTRSVLEPAGSLAVAGAKQYAEREGIENQTL
IAITSGANMNFDRMRFVAERAEVGEAREAVFAVTIPEERGSFRRFCELVGTRSVTEFNYRIADANSAHIFVGVQIRNRSE
SAQIAGAFEAHGFATVDLTFDELSKQHIRYMVGGRSPLAHDERLFRFEFPERPGALMKFLSSMAPNWNISLFHYRNQGAD
YSSILVGIQVPESENAAFDQFLATLGYPNWEETQNPVYRLFLAS

Sequences:

>Translated_524_residues
MLLHELKQAAEAADSVALRHDYLKKTLTARVYDVARETELERAPNLSARLRNPVYLKREDNQPVFSFKVRGAYNKMAHIP
AEALERGVITASAGNHAQGVALSAARMGVKAIIVVPVTTPQVKVDAVRAHGGPTVEVVQFGESYSDAYGHAVKLQEERDL
TFVHPFDDPYVIAGQGTVAMEILSQHQGPIHAIFVPIGGGGLAAGVAAYVKSVRPEIKVIGVQTDDSCAMAASLKAGERV
TLNEVGLFSDGTAVKLVGEETFRLCREYLDDVLLVDTDALCAAIKDVFQDTRSVLEPAGSLAVAGAKQYAEREGIENQTL
IAITSGANMNFDRMRFVAERAEVGEAREAVFAVTIPEERGSFRRFCELVGTRSVTEFNYRIADANSAHIFVGVQIRNRSE
SAQIAGAFEAHGFATVDLTFDELSKQHIRYMVGGRSPLAHDERLFRFEFPERPGALMKFLSSMAPNWNISLFHYRNQGAD
YSSILVGIQVPESENAAFDQFLATLGYPNWEETQNPVYRLFLAS
>Mature_524_residues
MLLHELKQAAEAADSVALRHDYLKKTLTARVYDVARETELERAPNLSARLRNPVYLKREDNQPVFSFKVRGAYNKMAHIP
AEALERGVITASAGNHAQGVALSAARMGVKAIIVVPVTTPQVKVDAVRAHGGPTVEVVQFGESYSDAYGHAVKLQEERDL
TFVHPFDDPYVIAGQGTVAMEILSQHQGPIHAIFVPIGGGGLAAGVAAYVKSVRPEIKVIGVQTDDSCAMAASLKAGERV
TLNEVGLFSDGTAVKLVGEETFRLCREYLDDVLLVDTDALCAAIKDVFQDTRSVLEPAGSLAVAGAKQYAEREGIENQTL
IAITSGANMNFDRMRFVAERAEVGEAREAVFAVTIPEERGSFRRFCELVGTRSVTEFNYRIADANSAHIFVGVQIRNRSE
SAQIAGAFEAHGFATVDLTFDELSKQHIRYMVGGRSPLAHDERLFRFEFPERPGALMKFLSSMAPNWNISLFHYRNQGAD
YSSILVGIQVPESENAAFDQFLATLGYPNWEETQNPVYRLFLAS

Specific function: Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. The first step is a dehydration of threonine, followed by rehydration and liberation of ammonia [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=298, Percent_Identity=33.2214765100671, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI33469958, Length=318, Percent_Identity=28.9308176100629, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI19923959, Length=307, Percent_Identity=28.0130293159609, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790207, Length=504, Percent_Identity=53.1746031746032, Blast_Score=513, Evalue=1e-147,
Organism=Escherichia coli, GI1789505, Length=311, Percent_Identity=37.2990353697749, Blast_Score=177, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71991565, Length=321, Percent_Identity=28.6604361370716, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17537387, Length=386, Percent_Identity=29.2746113989637, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17508781, Length=254, Percent_Identity=31.496062992126, Blast_Score=112, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6320930, Length=517, Percent_Identity=48.1624758220503, Blast_Score=466, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6322631, Length=304, Percent_Identity=33.8815789473684, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6319788, Length=269, Percent_Identity=26.7657992565056, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21355833, Length=316, Percent_Identity=28.1645569620253, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24645328, Length=255, Percent_Identity=26.2745098039216, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005787
- InterPro:   IPR001721 [H]

Pfam domain/function: PF00291 PALP; PF00585 Thr_dehydrat_C [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 57443; Mature: 57443

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLHELKQAAEAADSVALRHDYLKKTLTARVYDVARETELERAPNLSARLRNPVYLKRED
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEECC
NQPVFSFKVRGAYNKMAHIPAEALERGVITASAGNHAQGVALSAARMGVKAIIVVPVTTP
CCCEEEEEECCCHHHHHCCCHHHHHCCEEEECCCCCCCCEEEHHHHCCEEEEEEEECCCC
QVKVDAVRAHGGPTVEVVQFGESYSDAYGHAVKLQEERDLTFVHPFDDPYVIAGQGTVAM
CEEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEEECCCCCCEEEECCCHHHH
EILSQHQGPIHAIFVPIGGGGLAAGVAAYVKSVRPEIKVIGVQTDDSCAMAASLKAGERV
HHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCCEE
TLNEVGLFSDGTAVKLVGEETFRLCREYLDDVLLVDTDALCAAIKDVFQDTRSVLEPAGS
EEECCCEECCCCEEEEECHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHCCCCC
LAVAGAKQYAEREGIENQTLIAITSGANMNFDRMRFVAERAEVGEAREAVFAVTIPEERG
EEEHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECHHCC
SFRRFCELVGTRSVTEFNYRIADANSAHIFVGVQIRNRSESAQIAGAFEAHGFATVDLTF
HHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEEEEECCCCCCCEEEEEECCCEEEEEEEH
DELSKQHIRYMVGGRSPLAHDERLFRFEFPERPGALMKFLSSMAPNWNISLFHYRNQGAD
HHHHHHHHHEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCC
YSSILVGIQVPESENAAFDQFLATLGYPNWEETQNPVYRLFLAS
CCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MLLHELKQAAEAADSVALRHDYLKKTLTARVYDVARETELERAPNLSARLRNPVYLKRED
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEECC
NQPVFSFKVRGAYNKMAHIPAEALERGVITASAGNHAQGVALSAARMGVKAIIVVPVTTP
CCCEEEEEECCCHHHHHCCCHHHHHCCEEEECCCCCCCCEEEHHHHCCEEEEEEEECCCC
QVKVDAVRAHGGPTVEVVQFGESYSDAYGHAVKLQEERDLTFVHPFDDPYVIAGQGTVAM
CEEEEEEECCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEEECCCCCCEEEECCCHHHH
EILSQHQGPIHAIFVPIGGGGLAAGVAAYVKSVRPEIKVIGVQTDDSCAMAASLKAGERV
HHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCCEE
TLNEVGLFSDGTAVKLVGEETFRLCREYLDDVLLVDTDALCAAIKDVFQDTRSVLEPAGS
EEECCCEECCCCEEEEECHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHCCCCC
LAVAGAKQYAEREGIENQTLIAITSGANMNFDRMRFVAERAEVGEAREAVFAVTIPEERG
EEEHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECHHCC
SFRRFCELVGTRSVTEFNYRIADANSAHIFVGVQIRNRSESAQIAGAFEAHGFATVDLTF
HHHHHHHHHCCCCEEEEEEEEECCCCCEEEEEEEEECCCCCCCEEEEEECCCEEEEEEEH
DELSKQHIRYMVGGRSPLAHDERLFRFEFPERPGALMKFLSSMAPNWNISLFHYRNQGAD
HHHHHHHHHEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCC
YSSILVGIQVPESENAAFDQFLATLGYPNWEETQNPVYRLFLAS
CCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA