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The map label for this gene is pkn1 [H]

Identifier: 91783680

GI number: 91783680

Start: 2561240

End: 2562394

Strand: Direct

Name: pkn1 [H]

Synonym: Bxe_A2134

Alternate gene names: 91783680

Gene position: 2561240-2562394 (Clockwise)

Preceding gene: 91783672

Following gene: 91783681

Centisome position: 52.31

GC content: 65.45

Gene sequence:

>1155_bases
ATGTTGTGGGGCGCCCTGCTCGTCATACTGCCCGCCTGTGTCGGCGCCGCGGTCAGTTGGGCCTTCACGCCGCACGCACC
CGCTCACCCGCAAATCGTTTTCGGCGACGGCACGCATGGTCCGCTCGGCATGGCGTGGGTGCCCGGCGGCCAGTTCCTCA
TGGGCAGCGACGCCAAACAGGCGCAACCGAACGAACGCCCCGCGCACAAGGTCAAGGTGCACGGCTTCTGGATGGACCGC
CATCACGTGACCAACGCCGAATTCCGCCGCTTCGTCGAAGCGACCGGCTACGTCACCACGGCCGAGAAGAAACCCGACTG
GGAGACCCTGAAAGTCCAGTTGCCGCCCGGCACGCCGCGCCCGCCCGAGAGCGCGATGGTGGCGGGTGCAATGGTGTTCG
TCGGCACCAGCCGTCCCGTGCCGCTAGACGACTATTCGCAGTGGTGGCGCTATGTGCCTGGCGCTAACTGGCGTCATCCA
GCCGGGCCTGAGAGCAACATCATCGGTAAAGATGATCACCCCGTGGTTCAAGTGTCCTACGAAGATGCGCAGGCTTATGC
GAAATGGGCCGGCAAGCGTCTGCCGACCGAAGCCGAATGGGAATTCGCCGCGCGCGGCGGCCTCGAACAGGCCACGTATG
CGTGGGGCGATCAGTTCTCTCCCAACGGCAAACAGATGGCCAACGTCTGGCAGGGCCAGCAGCCGCAGTCTTTCCCCGTT
GTCAACCCGAAAGCGGGTGGCGCGCTCGGTACAAGTCCGGTGGGTACTTTCCCGGCCAACGGCTACGGCCTTTCCGACAT
GACCGGCAACGCCTGGCAGTGGGTTGCCGACTGGTATCGCGCGGATCAGTTCAGGCGTGAGGCGGTAAGCACCAGCGCGA
TCGACAATCCGGTGGGCCCGAGCGAGTCGTGGGACCCCGCAGACCAGGGCGTGCCCGTCAACGCGCCCAAGCGTGTCACA
CGCGGCGGTTCGTTCCTCTGCAACGAAATCTATTGCCTGAGCTACCGGCCCAGCGCGAGACGCGGCACCGATCCCTACAA
CAGCATGTCGCATCTGGGCTTCCGGCTGGTGATGGACGAAGACACCTGGAAAGAAGCCGGTGCTCGCCAGGCTTCGGCGA
AAGCTGCCGGCGCGCCTGGAACCCCTGGCGGCTAG

Upstream 100 bases:

>100_bases
AAAAATGAAGAGTGAAAGAGATCGAGAGCCCGCAAAGTCGTCCCGCTCGAACGGGTCGGTCGCAGCAACCCAAACGCGCG
CCGGTCGCGTGCGCAAACTA

Downstream 100 bases:

>100_bases
CGCACACCGTACCGCTGGAAAACCCTTAGTTTCCGCGCCCGTAATCCGCCGGCGCGCATCGCGATCGTCCGTCTGATCGC
CCATCTAATTGAACCTGGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MLWGALLVILPACVGAAVSWAFTPHAPAHPQIVFGDGTHGPLGMAWVPGGQFLMGSDAKQAQPNERPAHKVKVHGFWMDR
HHVTNAEFRRFVEATGYVTTAEKKPDWETLKVQLPPGTPRPPESAMVAGAMVFVGTSRPVPLDDYSQWWRYVPGANWRHP
AGPESNIIGKDDHPVVQVSYEDAQAYAKWAGKRLPTEAEWEFAARGGLEQATYAWGDQFSPNGKQMANVWQGQQPQSFPV
VNPKAGGALGTSPVGTFPANGYGLSDMTGNAWQWVADWYRADQFRREAVSTSAIDNPVGPSESWDPADQGVPVNAPKRVT
RGGSFLCNEIYCLSYRPSARRGTDPYNSMSHLGFRLVMDEDTWKEAGARQASAKAAGAPGTPGG

Sequences:

>Translated_384_residues
MLWGALLVILPACVGAAVSWAFTPHAPAHPQIVFGDGTHGPLGMAWVPGGQFLMGSDAKQAQPNERPAHKVKVHGFWMDR
HHVTNAEFRRFVEATGYVTTAEKKPDWETLKVQLPPGTPRPPESAMVAGAMVFVGTSRPVPLDDYSQWWRYVPGANWRHP
AGPESNIIGKDDHPVVQVSYEDAQAYAKWAGKRLPTEAEWEFAARGGLEQATYAWGDQFSPNGKQMANVWQGQQPQSFPV
VNPKAGGALGTSPVGTFPANGYGLSDMTGNAWQWVADWYRADQFRREAVSTSAIDNPVGPSESWDPADQGVPVNAPKRVT
RGGSFLCNEIYCLSYRPSARRGTDPYNSMSHLGFRLVMDEDTWKEAGARQASAKAAGAPGTPGG
>Mature_384_residues
MLWGALLVILPACVGAAVSWAFTPHAPAHPQIVFGDGTHGPLGMAWVPGGQFLMGSDAKQAQPNERPAHKVKVHGFWMDR
HHVTNAEFRRFVEATGYVTTAEKKPDWETLKVQLPPGTPRPPESAMVAGAMVFVGTSRPVPLDDYSQWWRYVPGANWRHP
AGPESNIIGKDDHPVVQVSYEDAQAYAKWAGKRLPTEAEWEFAARGGLEQATYAWGDQFSPNGKQMANVWQGQQPQSFPV
VNPKAGGALGTSPVGTFPANGYGLSDMTGNAWQWVADWYRADQFRREAVSTSAIDNPVGPSESWDPADQGVPVNAPKRVT
RGGSFLCNEIYCLSYRPSARRGTDPYNSMSHLGFRLVMDEDTWKEAGARQASAKAAGAPGTPGG

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=317, Percent_Identity=41.6403785488959, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI257470975, Length=318, Percent_Identity=39.622641509434, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI257470977, Length=317, Percent_Identity=38.4858044164038, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI194248088, Length=325, Percent_Identity=35.0769230769231, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI194248087, Length=319, Percent_Identity=33.8557993730408, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI194248090, Length=230, Percent_Identity=38.695652173913, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI226437577, Length=215, Percent_Identity=40.4651162790698, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI20130397, Length=332, Percent_Identity=36.4457831325301, Blast_Score=199, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 41752; Mature: 41752

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWGALLVILPACVGAAVSWAFTPHAPAHPQIVFGDGTHGPLGMAWVPGGQFLMGSDAKQ
CHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCCEEEECCCCCEEECCCHHH
AQPNERPAHKVKVHGFWMDRHHVTNAEFRRFVEATGYVTTAEKKPDWETLKVQLPPGTPR
CCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCCCEEEEEECCCCCCC
PPESAMVAGAMVFVGTSRPVPLDDYSQWWRYVPGANWRHPAGPESNIIGKDDHPVVQVSY
CCHHHHHEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEH
EDAQAYAKWAGKRLPTEAEWEFAARGGLEQATYAWGDQFSPNGKQMANVWQGQQPQSFPV
HHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCC
VNPKAGGALGTSPVGTFPANGYGLSDMTGNAWQWVADWYRADQFRREAVSTSAIDNPVGP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SESWDPADQGVPVNAPKRVTRGGSFLCNEIYCLSYRPSARRGTDPYNSMSHLGFRLVMDE
CCCCCCCCCCCCCCCCHHHHCCCCEEECEEEEEECCCCCCCCCCCHHHHHHCCEEEEECC
DTWKEAGARQASAKAAGAPGTPGG
CHHHHHCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLWGALLVILPACVGAAVSWAFTPHAPAHPQIVFGDGTHGPLGMAWVPGGQFLMGSDAKQ
CHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEECCCCCCCCEEEECCCCCEEECCCHHH
AQPNERPAHKVKVHGFWMDRHHVTNAEFRRFVEATGYVTTAEKKPDWETLKVQLPPGTPR
CCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCCCEEEEEECCCCCCC
PPESAMVAGAMVFVGTSRPVPLDDYSQWWRYVPGANWRHPAGPESNIIGKDDHPVVQVSY
CCHHHHHEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEH
EDAQAYAKWAGKRLPTEAEWEFAARGGLEQATYAWGDQFSPNGKQMANVWQGQQPQSFPV
HHHHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCC
VNPKAGGALGTSPVGTFPANGYGLSDMTGNAWQWVADWYRADQFRREAVSTSAIDNPVGP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SESWDPADQGVPVNAPKRVTRGGSFLCNEIYCLSYRPSARRGTDPYNSMSHLGFRLVMDE
CCCCCCCCCCCCCCCCHHHHCCCCEEECEEEEEECCCCCCCCCCCHHHHHHCCEEEEECC
DTWKEAGARQASAKAAGAPGTPGG
CHHHHHCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]