Click here to switch to the map view.

The map label for this gene is epsB [H]

Identifier: 91783573

GI number: 91783573

Start: 2436233

End: 2438455

Strand: Direct

Name: epsB [H]

Synonym: Bxe_A2242

Alternate gene names: 91783573

Gene position: 2436233-2438455 (Clockwise)

Preceding gene: 91783572

Following gene: 91783574

Centisome position: 49.76

GC content: 65.63

Gene sequence:

>2223_bases
GTGAGCAACCAGATCTCTCCACACATGGCCGGTCCGATCAAGACCGAAGAAGAGGACGTCGTCCTCGGGCAACTGCTGCA
GGTGATCCTCGACGACATCTGGTGGCTGATCGCCATCGCCGCCGTGATCGTCGCGATTGCGGGTGCGTACTGCTTCCTCG
CCAAGCCGATCTATTCCGCCGATGCGCACGTGCGGGTCGAGCAGTCCGACAACACGTCACAGGCGCTCACGCAGACGCAA
ACGGGCGCGGCGATCACCACCGGCTCGACCGCGCTGCCGACCGACGCCGAGATCGAAATTATCAAGAGCCGCGGCGTGGT
CGGCCCGGTCGTGCAGCAGCTCAAACTGAACTTCAGCGTCACGCCGAAGACCTTCCCGCTGCTCGGCAGCATCGCCGCGC
GCATGGCGACGCCGGGTCAGCCGGCGCGTCCGTGGCTGGGCTTGTCGTCGTACGCATGGGGCGGTGAAGAGGCCGACGTC
GATTCGATCGACGTGATCCCCGCGCTGGAAGGTCAGAAGCTGACCATGAAGGTGCTGGACGACCAGCACTACGAACTGTA
TGCGACCAACGGCGCGCTGCTGCTGCGCGGCGTCGTCGGCCAGCAGGAACAGGGCGGCGGCGTGACCATGACGGTCAACA
AACTGGTGGCGCGCCCCGGCGAGGAATTCACGGTGATGCGCGCCAACGACCTCGACGCGATCACCGCGTTCCAGTCGGCC
ATCACGGTGCAGGAGCAGGGCAAGCAGACCGGCGTGATCCAGATTTCGCTGGAAGACAAGAGCCCGGAACATGCCGCGCT
GGTCGCCAACGCGCTCGCCCAGTCGTATGTGCGCCAGCACGTGCTGAACAAGCAGGCCGACGCGAGCAAGATGCTCGACT
TCCTGAAGAGCGAAGAGCCGCGCCTGAAGGCCGACCTCGAACGCGCCGAAGCCGCGCTGACCGCGTATCAGCGTCAGTCC
GGCTCGATCAACGCGAGCGACGAAGCCAAGGTGTACCTGGAAGGCAGCATGCAGTACGAACAGCAGATCGCCGGCTTGCG
CCTGCAGATGGCGCAGCTCACCGAGCGTTACGGCGACGACCACCCGATGCTGGTGGCCGCGCGCGCGCAGATGGCCGAAT
TGCAGGCGCAGCGCGCCAAATACGCCGACCGCTTCCGCGATCTGCCGGCCACCGAAGTGAAGGCCGTGCAGTTGCAGCGC
GACGCGAAAGTGGCCGAAGACATCTACGTGCTGCTGCTCAACCGGGTGCAGGAGTTGTCGGTGCAGAAGGCCGGCACCGG
CGGCAACGTGCATATCGTCGACGCCGCGCTGCGCCCGGGCGTGCCGGTCAAGCCGAAGAAGGCGCTGATCCTCTCGGCGG
CGGTGATTCTCGGGCTGATCGCGGGCACCGGCTTCGTGTTCCTGCGCCGCAATATGTTCAAGGGCATCGACGACCCCGAT
CACATCGAGCGTGCGTTCCACCTGCCGGTGTTCGGCCTCGTACCGCAAAGCGCCGAACAGGCCGTGCTCGAAAGCAGCTT
CCTGCGCGGCGGCGAACGCCTGCGCTCGGTGCTGGCGAATGCGCGGCCGAAGGACGTCACGGTGGAAAGCCTGCGCAGTC
TGCGCACCTCCATGCAGTTCACCATGATGGACGCGAAGAACCGCATCGTCATGCTGACGGGGCCGATGGCCGGCGTCGGC
AAGAGCTTCCTGACGGTCAACCTCGCGGTGCTGCTCGCGAATTCGGGCAAGCGTGTGCTGATGATCGACGGCGACATGCG
CCGCGGTGTGCTCGAACGCTATCTGGGCGGTGTGCCGGATAACGGTCTCTCTGAATTGCTGAGCGGCCAGATCTCGCTGG
AAGAAGCGATTCGCAGCTCGAATGTGGAGGGCCTGAGCTTCATCTCGTGCGGCCGCCGTCCGCCGAATCCGTCGGAGCTG
CTGATGTCGCCGCGCCTGCCGCAATACCTCGAAGGTCTCGCCAAGCGCTACGACGTGATCATGATCGATACGCCGCCGGT
GCTGGCCGTGACCGATGCGTCGATCATCGGCGCGTATGCCGGATCGACCTTCTTCGTGATGCGCTCGGGCGTGCACAGCG
AGGGCGAAATCGCCGACGCGCTCAAGCGTCTGCGCGCGGCCGGCGTGCACGTGCAGGGCGGCATTTTCAACGGCATGCCG
GCGCGTTCGCGCGGCGGCTACGACCGGGGCTATGCGGCGGTTCAGGAATACCTGAGCACCTGA

Upstream 100 bases:

>100_bases
ATCATCTGAACCGCTGTCGTCAGGCCCGCGCCGCGCCGCCCATCGGGGACGCGGCGCGGGACCGAAGCAAACGCGATGTA
ACCGATACGGGAAGCGAATT

Downstream 100 bases:

>100_bases
GCCGGATGCGTTTCGGGATGCAATCCGGTCTTCGCGCAACGACGATTAAAAAGGACATCACGATGAAAGTGACGGTACTG
GTTCCGACTTTCCGACGCCC

Product: protein-tyrosine kinase

Products: ADP; protein tyrosine phosphate [C]

Alternate protein names: EPS I polysaccharide export protein epsB [H]

Number of amino acids: Translated: 740; Mature: 739

Protein sequence:

>740_residues
MSNQISPHMAGPIKTEEEDVVLGQLLQVILDDIWWLIAIAAVIVAIAGAYCFLAKPIYSADAHVRVEQSDNTSQALTQTQ
TGAAITTGSTALPTDAEIEIIKSRGVVGPVVQQLKLNFSVTPKTFPLLGSIAARMATPGQPARPWLGLSSYAWGGEEADV
DSIDVIPALEGQKLTMKVLDDQHYELYATNGALLLRGVVGQQEQGGGVTMTVNKLVARPGEEFTVMRANDLDAITAFQSA
ITVQEQGKQTGVIQISLEDKSPEHAALVANALAQSYVRQHVLNKQADASKMLDFLKSEEPRLKADLERAEAALTAYQRQS
GSINASDEAKVYLEGSMQYEQQIAGLRLQMAQLTERYGDDHPMLVAARAQMAELQAQRAKYADRFRDLPATEVKAVQLQR
DAKVAEDIYVLLLNRVQELSVQKAGTGGNVHIVDAALRPGVPVKPKKALILSAAVILGLIAGTGFVFLRRNMFKGIDDPD
HIERAFHLPVFGLVPQSAEQAVLESSFLRGGERLRSVLANARPKDVTVESLRSLRTSMQFTMMDAKNRIVMLTGPMAGVG
KSFLTVNLAVLLANSGKRVLMIDGDMRRGVLERYLGGVPDNGLSELLSGQISLEEAIRSSNVEGLSFISCGRRPPNPSEL
LMSPRLPQYLEGLAKRYDVIMIDTPPVLAVTDASIIGAYAGSTFFVMRSGVHSEGEIADALKRLRAAGVHVQGGIFNGMP
ARSRGGYDRGYAAVQEYLST

Sequences:

>Translated_740_residues
MSNQISPHMAGPIKTEEEDVVLGQLLQVILDDIWWLIAIAAVIVAIAGAYCFLAKPIYSADAHVRVEQSDNTSQALTQTQ
TGAAITTGSTALPTDAEIEIIKSRGVVGPVVQQLKLNFSVTPKTFPLLGSIAARMATPGQPARPWLGLSSYAWGGEEADV
DSIDVIPALEGQKLTMKVLDDQHYELYATNGALLLRGVVGQQEQGGGVTMTVNKLVARPGEEFTVMRANDLDAITAFQSA
ITVQEQGKQTGVIQISLEDKSPEHAALVANALAQSYVRQHVLNKQADASKMLDFLKSEEPRLKADLERAEAALTAYQRQS
GSINASDEAKVYLEGSMQYEQQIAGLRLQMAQLTERYGDDHPMLVAARAQMAELQAQRAKYADRFRDLPATEVKAVQLQR
DAKVAEDIYVLLLNRVQELSVQKAGTGGNVHIVDAALRPGVPVKPKKALILSAAVILGLIAGTGFVFLRRNMFKGIDDPD
HIERAFHLPVFGLVPQSAEQAVLESSFLRGGERLRSVLANARPKDVTVESLRSLRTSMQFTMMDAKNRIVMLTGPMAGVG
KSFLTVNLAVLLANSGKRVLMIDGDMRRGVLERYLGGVPDNGLSELLSGQISLEEAIRSSNVEGLSFISCGRRPPNPSEL
LMSPRLPQYLEGLAKRYDVIMIDTPPVLAVTDASIIGAYAGSTFFVMRSGVHSEGEIADALKRLRAAGVHVQGGIFNGMP
ARSRGGYDRGYAAVQEYLST
>Mature_739_residues
SNQISPHMAGPIKTEEEDVVLGQLLQVILDDIWWLIAIAAVIVAIAGAYCFLAKPIYSADAHVRVEQSDNTSQALTQTQT
GAAITTGSTALPTDAEIEIIKSRGVVGPVVQQLKLNFSVTPKTFPLLGSIAARMATPGQPARPWLGLSSYAWGGEEADVD
SIDVIPALEGQKLTMKVLDDQHYELYATNGALLLRGVVGQQEQGGGVTMTVNKLVARPGEEFTVMRANDLDAITAFQSAI
TVQEQGKQTGVIQISLEDKSPEHAALVANALAQSYVRQHVLNKQADASKMLDFLKSEEPRLKADLERAEAALTAYQRQSG
SINASDEAKVYLEGSMQYEQQIAGLRLQMAQLTERYGDDHPMLVAARAQMAELQAQRAKYADRFRDLPATEVKAVQLQRD
AKVAEDIYVLLLNRVQELSVQKAGTGGNVHIVDAALRPGVPVKPKKALILSAAVILGLIAGTGFVFLRRNMFKGIDDPDH
IERAFHLPVFGLVPQSAEQAVLESSFLRGGERLRSVLANARPKDVTVESLRSLRTSMQFTMMDAKNRIVMLTGPMAGVGK
SFLTVNLAVLLANSGKRVLMIDGDMRRGVLERYLGGVPDNGLSELLSGQISLEEAIRSSNVEGLSFISCGRRPPNPSELL
MSPRLPQYLEGLAKRYDVIMIDTPPVLAVTDASIIGAYAGSTFFVMRSGVHSEGEIADALKRLRAAGVHVQGGIFNGMPA
RSRGGYDRGYAAVQEYLST

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor. May be involved in an ATP-dependent process in the pathway for EPS I production, possibly export of the trimeric repeat units across the in

COG id: COG3206

COG function: function code M; Uncharacterized protein involved in exopolysaccharide biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the etk/wzc family [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=735, Percent_Identity=35.5102040816327, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1787216, Length=730, Percent_Identity=33.013698630137, Blast_Score=413, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702
- InterPro:   IPR005700
- InterPro:   IPR003856 [H]

Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]

EC number: 2.7.1.112 [C]

Molecular weight: Translated: 80053; Mature: 79922

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQISPHMAGPIKTEEEDVVLGQLLQVILDDIWWLIAIAAVIVAIAGAYCFLAKPIYSA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCC
DAHVRVEQSDNTSQALTQTQTGAAITTGSTALPTDAEIEIIKSRGVVGPVVQQLKLNFSV
CCEEEEECCCCHHHHHHHHCCCCEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHCCEEE
TPKTFPLLGSIAARMATPGQPARPWLGLSSYAWGGEEADVDSIDVIPALEGQKLTMKVLD
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
DQHYELYATNGALLLRGVVGQQEQGGGVTMTVNKLVARPGEEFTVMRANDLDAITAFQSA
CCCEEEEEECCEEEEEECCCCCCCCCCEEEEEHHHHCCCCCCEEEEECCCCHHHHHHHHH
ITVQEQGKQTGVIQISLEDKSPEHAALVANALAQSYVRQHVLNKQADASKMLDFLKSEEP
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
RLKADLERAEAALTAYQRQSGSINASDEAKVYLEGSMQYEQQIAGLRLQMAQLTERYGDD
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCC
HPMLVAARAQMAELQAQRAKYADRFRDLPATEVKAVQLQRDAKVAEDIYVLLLNRVQELS
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQKAGTGGNVHIVDAALRPGVPVKPKKALILSAAVILGLIAGTGFVFLRRNMFKGIDDPD
HHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHH
HIERAFHLPVFGLVPQSAEQAVLESSFLRGGERLRSVLANARPKDVTVESLRSLRTSMQF
HHHHHHCCCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHE
TMMDAKNRIVMLTGPMAGVGKSFLTVNLAVLLANSGKRVLMIDGDMRRGVLERYLGGVPD
EEEECCCCEEEEECCCHHCCCHHHHHEEEEEEECCCCEEEEECCHHHHHHHHHHHCCCCC
NGLSELLSGQISLEEAIRSSNVEGLSFISCGRRPPNPSELLMSPRLPQYLEGLAKRYDVI
CCHHHHHCCCCHHHHHHHHCCCCCEEHEECCCCCCCHHHHCCCCCCHHHHHHHHHHCCEE
MIDTPPVLAVTDASIIGAYAGSTFFVMRSGVHSEGEIADALKRLRAAGVHVQGGIFNGMP
EECCCCEEEEECCHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEECCCCCCCC
ARSRGGYDRGYAAVQEYLST
CCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SNQISPHMAGPIKTEEEDVVLGQLLQVILDDIWWLIAIAAVIVAIAGAYCFLAKPIYSA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCC
DAHVRVEQSDNTSQALTQTQTGAAITTGSTALPTDAEIEIIKSRGVVGPVVQQLKLNFSV
CCEEEEECCCCHHHHHHHHCCCCEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHCCEEE
TPKTFPLLGSIAARMATPGQPARPWLGLSSYAWGGEEADVDSIDVIPALEGQKLTMKVLD
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEC
DQHYELYATNGALLLRGVVGQQEQGGGVTMTVNKLVARPGEEFTVMRANDLDAITAFQSA
CCCEEEEEECCEEEEEECCCCCCCCCCEEEEEHHHHCCCCCCEEEEECCCCHHHHHHHHH
ITVQEQGKQTGVIQISLEDKSPEHAALVANALAQSYVRQHVLNKQADASKMLDFLKSEEP
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
RLKADLERAEAALTAYQRQSGSINASDEAKVYLEGSMQYEQQIAGLRLQMAQLTERYGDD
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCC
HPMLVAARAQMAELQAQRAKYADRFRDLPATEVKAVQLQRDAKVAEDIYVLLLNRVQELS
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQKAGTGGNVHIVDAALRPGVPVKPKKALILSAAVILGLIAGTGFVFLRRNMFKGIDDPD
HHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHH
HIERAFHLPVFGLVPQSAEQAVLESSFLRGGERLRSVLANARPKDVTVESLRSLRTSMQF
HHHHHHCCCEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHE
TMMDAKNRIVMLTGPMAGVGKSFLTVNLAVLLANSGKRVLMIDGDMRRGVLERYLGGVPD
EEEECCCCEEEEECCCHHCCCHHHHHEEEEEEECCCCEEEEECCHHHHHHHHHHHCCCCC
NGLSELLSGQISLEEAIRSSNVEGLSFISCGRRPPNPSELLMSPRLPQYLEGLAKRYDVI
CCHHHHHCCCCHHHHHHHHCCCCCEEHEECCCCCCCHHHHCCCCCCHHHHHHHHHHCCEE
MIDTPPVLAVTDASIIGAYAGSTFFVMRSGVHSEGEIADALKRLRAAGVHVQGGIFNGMP
EECCCCEEEEECCHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEECCCCCCCC
ARSRGGYDRGYAAVQEYLST
CCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; a protein tyrosine [C]

Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]