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The map label for this gene is epsA [H]

Identifier: 91783572

GI number: 91783572

Start: 2434910

End: 2436133

Strand: Direct

Name: epsA [H]

Synonym: Bxe_A2243

Alternate gene names: 91783572

Gene position: 2434910-2436133 (Clockwise)

Preceding gene: 91783571

Following gene: 91783573

Centisome position: 49.73

GC content: 64.22

Gene sequence:

>1224_bases
ATGAAAAAACTCACTGCACACCCGTTCACGGACGGCAAGTCGACGAATTTCAGGTCCGGACTCGCCGCCACGCTTTTGCT
GACGTCCTTTCTGTCGGCCTGCGCCACCGCACCTGGCAACTACCTCGATACCTCCCGTCTGAAAGACGACGGCCAGCACG
ACAGTCAACCCGCCGAAACCTATCCGGTCCATCTCATCGACGCGAATGTCGTGACCGCGCAGGCGCAAGCCGCCGCGGCG
AAGATCCAGGTACTGCCGACCTCCACCGTGAGCGACCCGTCGCAGTATGTGTACCGGCTCGCGCCGCAGGACATTCTCGG
CATCACCGTGTGGGATCACCCGGAACTGACCACGCCGCAGGGCAGCACGCTGTCGGCGGGCGGCAACACCACGCAGTCGA
TCGGCGGCGCGTTGCAGCAGCCGTACACGGCCGCGCTGCCGGGGCAGGCCGATCCGTACGGCCAGACCATTGCCGCCGAC
GGCACGATCTTTTTCCCGTTCGTCGGCCGCATTCGCGCCGCCGGCAAAACCGTCAGCGAGTTGCGCGATCAGTTGAGCAC
CGGACTCGTGCGCTATATCCGCAATCCGCAGGTGGACGTGCGCGTGCTGTCGTATCGCGGCCAGAAAGTGCAGGTGACCG
GCGAAGTGAAGACGCCGGGCCCGCTCGCGGTGAGCGACGTGCCGCTCACGCTGGTCGACGCGATCACGCGTTCGGGCGGC
ACCAATGCGGACGCCGATATTCAGCGCGTGCGTCTCACGCGCAACAACAAGCTCTACATACTCGACGCCGACCGCATGCT
CGATCGCGGCGACACCACGCAGAACGTGATGCTGCAAAACGGCGACGTGATCAACGTACCGGACCGCACCGACAGCCGGA
TCTTCGTGATGGGCGAAGTGAAGACGCCGATCCAGCTGCCGATCATCAGGGGGCGCATGACGATCGCCGACGCGCTCACG
CAGGCCGGCGGCATTCTCGACACGGACGCCAATCCGCGTCAGATCTTCGTGATGCGCGGCATGAGAGATCACCCGACCAC
GCCGGACGTGTATCGCCTCGACATGACGCAGCCGGACGCCATCATGCTGTCCTCGCAATTCCAGTTGCAGCCGCTGGATG
TCGTGTACGTGGGCACCGCTGCGTCGACCACCTTCAACCGTGTGTTGCAGCAGGTGCTGCCGACTGTGCAGACGTTGTTC
TACCTGAAACAGCTGACGCGCTGA

Upstream 100 bases:

>100_bases
CCGACGTCGCCGATCCGCACGGCGGGGCGGAAACCGCTTATAGGGAGAGTCTCGTGCTCATCGAACATCTGGTCATGGGA
TGGCTGAAAAAAATATGCTG

Downstream 100 bases:

>100_bases
TCATCTGAACCGCTGTCGTCAGGCCCGCGCCGCGCCGCCCATCGGGGACGCGGCGCGGGACCGAAGCAAACGCGATGTAA
CCGATACGGGAAGCGAATTG

Product: polysaccharide (EPS I) exporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKKLTAHPFTDGKSTNFRSGLAATLLLTSFLSACATAPGNYLDTSRLKDDGQHDSQPAETYPVHLIDANVVTAQAQAAAA
KIQVLPTSTVSDPSQYVYRLAPQDILGITVWDHPELTTPQGSTLSAGGNTTQSIGGALQQPYTAALPGQADPYGQTIAAD
GTIFFPFVGRIRAAGKTVSELRDQLSTGLVRYIRNPQVDVRVLSYRGQKVQVTGEVKTPGPLAVSDVPLTLVDAITRSGG
TNADADIQRVRLTRNNKLYILDADRMLDRGDTTQNVMLQNGDVINVPDRTDSRIFVMGEVKTPIQLPIIRGRMTIADALT
QAGGILDTDANPRQIFVMRGMRDHPTTPDVYRLDMTQPDAIMLSSQFQLQPLDVVYVGTAASTTFNRVLQQVLPTVQTLF
YLKQLTR

Sequences:

>Translated_407_residues
MKKLTAHPFTDGKSTNFRSGLAATLLLTSFLSACATAPGNYLDTSRLKDDGQHDSQPAETYPVHLIDANVVTAQAQAAAA
KIQVLPTSTVSDPSQYVYRLAPQDILGITVWDHPELTTPQGSTLSAGGNTTQSIGGALQQPYTAALPGQADPYGQTIAAD
GTIFFPFVGRIRAAGKTVSELRDQLSTGLVRYIRNPQVDVRVLSYRGQKVQVTGEVKTPGPLAVSDVPLTLVDAITRSGG
TNADADIQRVRLTRNNKLYILDADRMLDRGDTTQNVMLQNGDVINVPDRTDSRIFVMGEVKTPIQLPIIRGRMTIADALT
QAGGILDTDANPRQIFVMRGMRDHPTTPDVYRLDMTQPDAIMLSSQFQLQPLDVVYVGTAASTTFNRVLQQVLPTVQTLF
YLKQLTR
>Mature_407_residues
MKKLTAHPFTDGKSTNFRSGLAATLLLTSFLSACATAPGNYLDTSRLKDDGQHDSQPAETYPVHLIDANVVTAQAQAAAA
KIQVLPTSTVSDPSQYVYRLAPQDILGITVWDHPELTTPQGSTLSAGGNTTQSIGGALQQPYTAALPGQADPYGQTIAAD
GTIFFPFVGRIRAAGKTVSELRDQLSTGLVRYIRNPQVDVRVLSYRGQKVQVTGEVKTPGPLAVSDVPLTLVDAITRSGG
TNADADIQRVRLTRNNKLYILDADRMLDRGDTTQNVMLQNGDVINVPDRTDSRIFVMGEVKTPIQLPIIRGRMTIADALT
QAGGILDTDANPRQIFVMRGMRDHPTTPDVYRLDMTQPDAIMLSSQFQLQPLDVVYVGTAASTTFNRVLQQVLPTVQTLF
YLKQLTR

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1787218, Length=393, Percent_Identity=35.1145038167939, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI1788376, Length=394, Percent_Identity=33.502538071066, Blast_Score=221, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715
- InterPro:   IPR019554 [H]

Pfam domain/function: PF02563 Poly_export; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 44196; Mature: 44196

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLTAHPFTDGKSTNFRSGLAATLLLTSFLSACATAPGNYLDTSRLKDDGQHDSQPAET
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCC
YPVHLIDANVVTAQAQAAAAKIQVLPTSTVSDPSQYVYRLAPQDILGITVWDHPELTTPQ
CCEEEEECCEEEHHHHHCEEEEEEEECCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCC
GSTLSAGGNTTQSIGGALQQPYTAALPGQADPYGQTIAADGTIFFPFVGRIRAAGKTVSE
CCEEECCCCCHHHHHHHHCCCCEEECCCCCCCCCCEEECCCEEEECHHHHHHHCCHHHHH
LRDQLSTGLVRYIRNPQVDVRVLSYRGQKVQVTGEVKTPGPLAVSDVPLTLVDAITRSGG
HHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEECCCCCCEEECCCCHHHHHHHHHCCC
TNADADIQRVRLTRNNKLYILDADRMLDRGDTTQNVMLQNGDVINVPDRTDSRIFVMGEV
CCCCCCEEEEEEECCCEEEEEEHHHHHCCCCCCCEEEEECCCEEECCCCCCCEEEEEECC
KTPIQLPIIRGRMTIADALTQAGGILDTDANPRQIFVMRGMRDHPTTPDVYRLDMTQPDA
CCCEEEEEEECCHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCCCCCEEEEECCCCCE
IMLSSQFQLQPLDVVYVGTAASTTFNRVLQQVLPTVQTLFYLKQLTR
EEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKLTAHPFTDGKSTNFRSGLAATLLLTSFLSACATAPGNYLDTSRLKDDGQHDSQPAET
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCC
YPVHLIDANVVTAQAQAAAAKIQVLPTSTVSDPSQYVYRLAPQDILGITVWDHPELTTPQ
CCEEEEECCEEEHHHHHCEEEEEEEECCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCC
GSTLSAGGNTTQSIGGALQQPYTAALPGQADPYGQTIAADGTIFFPFVGRIRAAGKTVSE
CCEEECCCCCHHHHHHHHCCCCEEECCCCCCCCCCEEECCCEEEECHHHHHHHCCHHHHH
LRDQLSTGLVRYIRNPQVDVRVLSYRGQKVQVTGEVKTPGPLAVSDVPLTLVDAITRSGG
HHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEECCCCCCEEECCCCHHHHHHHHHCCC
TNADADIQRVRLTRNNKLYILDADRMLDRGDTTQNVMLQNGDVINVPDRTDSRIFVMGEV
CCCCCCEEEEEEECCCEEEEEEHHHHHCCCCCCCEEEEECCCEEECCCCCCCEEEEEECC
KTPIQLPIIRGRMTIADALTQAGGILDTDANPRQIFVMRGMRDHPTTPDVYRLDMTQPDA
CCCEEEEEEECCHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCCCCCEEEEECCCCCE
IMLSSQFQLQPLDVVYVGTAASTTFNRVLQQVLPTVQTLFYLKQLTR
EEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]