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The map label for this gene is udg [H]

Identifier: 91783570

GI number: 91783570

Start: 2432929

End: 2434377

Strand: Direct

Name: udg [H]

Synonym: Bxe_A2245

Alternate gene names: 91783570

Gene position: 2432929-2434377 (Clockwise)

Preceding gene: 91783569

Following gene: 91783571

Centisome position: 49.69

GC content: 64.53

Gene sequence:

>1449_bases
ATGAACCTGACGATCATCGGTAGTGGCTACGTAGGCCTCGTGACAGGCGCGTGTCTGGCCGACATTGGCCACGACGTGTT
CTGTCTCGACGTCGATCAGCGCAAGATCGACGTGCTCAACAACGGCGGCGTGCCGATCCATGAACCGGGTCTGCAGGAGA
TCATCGCGCGCAATCGCAAGGCCGGCCGCCTGAAGTTTTCGACCGACGTCGAAGCGGCGGTCGCGCACGGCGATATCCAG
TTCATCGCGGTCGGCACGCCGTCCGACGAAGACGGATCCGCCGACCTGCAATACGTGCTGGCCGCCGCGCGCAACATTGG
CCGCCATATGACGGGCTTCAAGGTGATCGTCGACAAATCCACTGTGCCGGTCGGCACGGCCTCGCGCGTGCGTGACGTGA
TCGCTGCCGAACTGGCCGGCCGCAACGCTGCGCACATGTTCTCAGTGGTGTCGAATCCCGAGTTCTTGAAAGAGGGCGCG
GCGGTGGAAGACTTCACGCGGCCCGATCGGATCGTGCTCGGTTGCGACGAAGACGTGCCGGGTGAAAAAGCGCGCGAGCT
GATGAAGCGCCTCTACGCGCCGTTCAACCGCAATCGCGAACGCACGCTGTACATGGACGTGCGCTCGGCCGAATTCACCA
AGTACGCGGCCAACGCCATGCTCGCCACGCGTATTTCGTACATGAACGAACTCGCGAATCTGGCCGACCGCGTCGGTGCG
GATATCGAGGCGGTGCGGCGCGGCATCGGGTCCGATCCGCGCATCGGCTACGACTTCCTGTATGCCGGTTGCGGCTACGG
CGGTTCGTGCTTTCCGAAGGACGTGCAGGCGCTGATCCGCACGGCCGCCGACCACAAGGCGAATCTGCGCATTCTCGAAG
CGGTGGAAGCGGTCAACGACACGCAGAAGCAGGTGCTCGCGCAGAAGATCGTCTCGCGTCTGGGCGAAGACCTGTCCGAC
CGCACCTTCGGCGTATGGGGCCTCGCCTTCAAGCCGAATACCGACGACATGCGCGAAGCGCCGAGCCGTCCGCTGATCGC
CGAACTGCTGCGCCGCGGCGCCCGCGTGAAGGCATACGATCCGGTCGCGATCGACGAATCGAAGCGGGTGTTCGCGCTGG
ATCTGAAGGACGTGCCGCAGCAGCATGCGCGCCTGTCGTTCGTGAAGGAAGAGATGGAAGCCGCCGAAGGCGCGGATGCG
CTGGTGATCCTCACCGAATGGAAGGTGTTCAAGAGCCCGGACTTCGATTCGCTCAAACGGATCCTCAGGACGCCGCTGAT
TTTCGACGGCCGCAACCTGTACGAGCCGGACGCGCTGCTCGAACTCGGTATCGAGTATCAGGCAATCGGCCGTCAGCACG
CGCTGCGCAGCGCCCCGGCGAAGGTCGGCGCGAACGGCTTGCCGCTCGCGCATGTGCCGGCGCTGAATGCCGCCGGAGCC
GGCCGCTGA

Upstream 100 bases:

>100_bases
AGGGATGCAAGAAAACCTGGGGCGGCCCGGCGTTTTCTTGCGGGCTTCGGTCACGCGTCATGTGACTTTTTACTGGATTC
AATTCTGCGAGGTGTAATAC

Downstream 100 bases:

>100_bases
GCTGCCGCCGGAGCGCCGCCATTGCACCGTCAAGCACCCGCTCAGCCGCCGTCACGCGCCTCATCACGGAGCCCGCCATG
TTTGCCAATGTTCTGATCGT

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDQRKIDVLNNGGVPIHEPGLQEIIARNRKAGRLKFSTDVEAAVAHGDIQ
FIAVGTPSDEDGSADLQYVLAAARNIGRHMTGFKVIVDKSTVPVGTASRVRDVIAAELAGRNAAHMFSVVSNPEFLKEGA
AVEDFTRPDRIVLGCDEDVPGEKARELMKRLYAPFNRNRERTLYMDVRSAEFTKYAANAMLATRISYMNELANLADRVGA
DIEAVRRGIGSDPRIGYDFLYAGCGYGGSCFPKDVQALIRTAADHKANLRILEAVEAVNDTQKQVLAQKIVSRLGEDLSD
RTFGVWGLAFKPNTDDMREAPSRPLIAELLRRGARVKAYDPVAIDESKRVFALDLKDVPQQHARLSFVKEEMEAAEGADA
LVILTEWKVFKSPDFDSLKRILRTPLIFDGRNLYEPDALLELGIEYQAIGRQHALRSAPAKVGANGLPLAHVPALNAAGA
GR

Sequences:

>Translated_482_residues
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDQRKIDVLNNGGVPIHEPGLQEIIARNRKAGRLKFSTDVEAAVAHGDIQ
FIAVGTPSDEDGSADLQYVLAAARNIGRHMTGFKVIVDKSTVPVGTASRVRDVIAAELAGRNAAHMFSVVSNPEFLKEGA
AVEDFTRPDRIVLGCDEDVPGEKARELMKRLYAPFNRNRERTLYMDVRSAEFTKYAANAMLATRISYMNELANLADRVGA
DIEAVRRGIGSDPRIGYDFLYAGCGYGGSCFPKDVQALIRTAADHKANLRILEAVEAVNDTQKQVLAQKIVSRLGEDLSD
RTFGVWGLAFKPNTDDMREAPSRPLIAELLRRGARVKAYDPVAIDESKRVFALDLKDVPQQHARLSFVKEEMEAAEGADA
LVILTEWKVFKSPDFDSLKRILRTPLIFDGRNLYEPDALLELGIEYQAIGRQHALRSAPAKVGANGLPLAHVPALNAAGA
GR
>Mature_482_residues
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDQRKIDVLNNGGVPIHEPGLQEIIARNRKAGRLKFSTDVEAAVAHGDIQ
FIAVGTPSDEDGSADLQYVLAAARNIGRHMTGFKVIVDKSTVPVGTASRVRDVIAAELAGRNAAHMFSVVSNPEFLKEGA
AVEDFTRPDRIVLGCDEDVPGEKARELMKRLYAPFNRNRERTLYMDVRSAEFTKYAANAMLATRISYMNELANLADRVGA
DIEAVRRGIGSDPRIGYDFLYAGCGYGGSCFPKDVQALIRTAADHKANLRILEAVEAVNDTQKQVLAQKIVSRLGEDLSD
RTFGVWGLAFKPNTDDMREAPSRPLIAELLRRGARVKAYDPVAIDESKRVFALDLKDVPQQHARLSFVKEEMEAAEGADA
LVILTEWKVFKSPDFDSLKRILRTPLIFDGRNLYEPDALLELGIEYQAIGRQHALRSAPAKVGANGLPLAHVPALNAAGA
GR

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=472, Percent_Identity=36.0169491525424, Blast_Score=276, Evalue=3e-74,
Organism=Homo sapiens, GI296040438, Length=375, Percent_Identity=36.5333333333333, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI296040443, Length=322, Percent_Identity=36.9565217391304, Blast_Score=195, Evalue=6e-50,
Organism=Escherichia coli, GI1788340, Length=370, Percent_Identity=28.3783783783784, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI48994968, Length=442, Percent_Identity=26.9230769230769, Blast_Score=131, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17560350, Length=466, Percent_Identity=36.0515021459227, Blast_Score=258, Evalue=5e-69,
Organism=Drosophila melanogaster, GI17136908, Length=471, Percent_Identity=35.031847133758, Blast_Score=260, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 52580; Mature: 52580

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDQRKIDVLNNGGVPIHEPGLQEIIARNRK
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHCCCC
AGRLKFSTDVEAAVAHGDIQFIAVGTPSDEDGSADLQYVLAAARNIGRHMTGFKVIVDKS
CCCEEECCCHHHHEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
TVPVGTASRVRDVIAAELAGRNAAHMFSVVSNPEFLKEGAAVEDFTRPDRIVLGCDEDVP
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCCHHHCCCCCEEEEECCCCCC
GEKARELMKRLYAPFNRNRERTLYMDVRSAEFTKYAANAMLATRISYMNELANLADRVGA
CHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIEAVRRGIGSDPRIGYDFLYAGCGYGGSCFPKDVQALIRTAADHKANLRILEAVEAVND
CHHHHHHCCCCCCCCCHHHHEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TQKQVLAQKIVSRLGEDLSDRTFGVWGLAFKPNTDDMREAPSRPLIAELLRRGARVKAYD
HHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHCCCCCHHHHHHHCCCCEEECC
PVAIDESKRVFALDLKDVPQQHARLSFVKEEMEAAEGADALVILTEWKVFKSPDFDSLKR
CEEECCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEECEECCCCCHHHHHH
ILRTPLIFDGRNLYEPDALLELGIEYQAIGRQHALRSAPAKVGANGLPLAHVPALNAAGA
HHHCCCEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCC
GR
CC
>Mature Secondary Structure
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDQRKIDVLNNGGVPIHEPGLQEIIARNRK
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHCCCC
AGRLKFSTDVEAAVAHGDIQFIAVGTPSDEDGSADLQYVLAAARNIGRHMTGFKVIVDKS
CCCEEECCCHHHHEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
TVPVGTASRVRDVIAAELAGRNAAHMFSVVSNPEFLKEGAAVEDFTRPDRIVLGCDEDVP
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCCHHHCCCCCEEEEECCCCCC
GEKARELMKRLYAPFNRNRERTLYMDVRSAEFTKYAANAMLATRISYMNELANLADRVGA
CHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIEAVRRGIGSDPRIGYDFLYAGCGYGGSCFPKDVQALIRTAADHKANLRILEAVEAVND
CHHHHHHCCCCCCCCCHHHHEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TQKQVLAQKIVSRLGEDLSDRTFGVWGLAFKPNTDDMREAPSRPLIAELLRRGARVKAYD
HHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHCCCCCHHHHHHHCCCCEEECC
PVAIDESKRVFALDLKDVPQQHARLSFVKEEMEAAEGADALVILTEWKVFKSPDFDSLKR
CEEECCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEECEECCCCCHHHHHH
ILRTPLIFDGRNLYEPDALLELGIEYQAIGRQHALRSAPAKVGANGLPLAHVPALNAAGA
HHHCCCEECCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCC
GR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]