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The map label for this gene is otsA [H]

Identifier: 91783559

GI number: 91783559

Start: 2420520

End: 2421932

Strand: Direct

Name: otsA [H]

Synonym: Bxe_A2256

Alternate gene names: 91783559

Gene position: 2420520-2421932 (Clockwise)

Preceding gene: 91783558

Following gene: 91783560

Centisome position: 49.44

GC content: 64.4

Gene sequence:

>1413_bases
ATGGGGCGATTGATCGTCGTGTCGAATCGCGTCGCAACGCCGACGGAAACCAAGGGATCGGCCGGCGGCCTCGCGGTCGG
CGTATTCGGCGCGCTGAAGGATGCCGGAGGCGTGTGGTTCGGCTGGAGCGGCGACGTGGTCAGCGAGACCGTCGCGAACG
CCGGTCCGACGCTGGAGCAGGACGGCGCGGTGACCTTCGCGACCGTAGGGCTCACGCGCAAGGATTACGACCAGTACTAT
CGCGGCTTTTCGAACGCGACATTGTGGCCGGTGTTCCACTACCGCAACGACCTCGCGCGCTACGAGCGCGAGGAATACAC
GGGCTACCGGCGCGTCAACGCGTGGCTCGCGCACAAGCTGATCAAGCTGCTCGAACCCGACGACGTGATCTGGATTCACG
ACTACCACCTGATCCCGTTCGCCGAGGCGCTGCGCAACGAGGGTGTCACGAACCGCATCGGCTTCTTCCTGCACATTCCG
TTTCCCGCGCCGCAGATCCTGCTCAACATTCCGCCGCACGAGGAACTGGTGAAGTCGCTGTCGTGCTACGACCTGCTGGG
CTTCCAGACCGCCACCGACGAACTCGCGTTCAAGGATTACGTCACGCGCCACGCGCGCGGCACGGTGAGTGCGGACGGTC
TCGTCGAAGCGTTCGGCCGCAAGCTGCGCACCGGCGTCTACCGGATCGGCGTGTTCCCCGACGAAATCGCCGAGCAGGCG
AAGCGCTACGAAAGCCGTCAGCACGTGCTCGACCTGAAGCAGAGCCTGGAAGGGCGCAAGCTGATCATGAGCGTCGACCG
GCTGGACTATTCGAAGGGACTGGTCGAGCGGTTCCGGGCCTTCGAGCATCTGCTGGAGCGCTCGCCGGAATGGCGCGGCA
ACGTCACGCTGGTGCAGATCGCGCCGCCCACCCGTTCGGACGTCGCCACCTATCAGAAGATTCGCCAGGATCTGGAGTAC
GAAGCGGGGCGCATCAATGGCCGCTACTCGGGTCTCGACTACACGCCGATCCGCTATCTGAATCAGCAGTACGACCGCTG
GAAGCTGATGTCGCTGTTTCGCGAATCGCAGATCGGTTTCGTCACGCCGCTGCACGACGGTATGAATCTGGTCGCGAAGG
AATACGTCGCCGCGCAGAATCCCGACGATCCCGGCGTGCTGGTGCTGTCGATTTTCGCGGGTGCGGCGGCGGAGCTGAGC
GGCGCGCTGCTCGTCAATCCACATGATGCGATCGGCATGTGCGAAGCCTTGCAGCGCGCGTTGCAGATGCCGCTCGACGC
ACGTCAGCGGCGCCATGAAATCAACATGGCCGCGCTGCGCAAGAACGATCTCGGCGTGTGGCGCGACACGTTCCTGCACG
ATCTGCGCAGCGTGCCGGTGCAGCAGCCAGGCAAGGGTGGCGGGCATAACTGA

Upstream 100 bases:

>100_bases
TCAGGGTGGCTCGGGTTCCGTCGCGCGATTGCGCGGGACGCCGCCGGGACCTGATGCAACGCACCCGCGCGCGCCGCGCG
AACCAAGGAGGACATGCAAC

Downstream 100 bases:

>100_bases
TGGGGCGTCGTGACCCATACCTGGCGTGTTCGTCGCGCGGGCGATTCGCCGCGTGCGGGTGCGTAGCGGAATTACGGAAC
ACGCGCGCGTGCGTGACTGA

Product: Alpha,alpha-trehalose-phosphate synthase(UDP- forming)

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MGRLIVVSNRVATPTETKGSAGGLAVGVFGALKDAGGVWFGWSGDVVSETVANAGPTLEQDGAVTFATVGLTRKDYDQYY
RGFSNATLWPVFHYRNDLARYEREEYTGYRRVNAWLAHKLIKLLEPDDVIWIHDYHLIPFAEALRNEGVTNRIGFFLHIP
FPAPQILLNIPPHEELVKSLSCYDLLGFQTATDELAFKDYVTRHARGTVSADGLVEAFGRKLRTGVYRIGVFPDEIAEQA
KRYESRQHVLDLKQSLEGRKLIMSVDRLDYSKGLVERFRAFEHLLERSPEWRGNVTLVQIAPPTRSDVATYQKIRQDLEY
EAGRINGRYSGLDYTPIRYLNQQYDRWKLMSLFRESQIGFVTPLHDGMNLVAKEYVAAQNPDDPGVLVLSIFAGAAAELS
GALLVNPHDAIGMCEALQRALQMPLDARQRRHEINMAALRKNDLGVWRDTFLHDLRSVPVQQPGKGGGHN

Sequences:

>Translated_470_residues
MGRLIVVSNRVATPTETKGSAGGLAVGVFGALKDAGGVWFGWSGDVVSETVANAGPTLEQDGAVTFATVGLTRKDYDQYY
RGFSNATLWPVFHYRNDLARYEREEYTGYRRVNAWLAHKLIKLLEPDDVIWIHDYHLIPFAEALRNEGVTNRIGFFLHIP
FPAPQILLNIPPHEELVKSLSCYDLLGFQTATDELAFKDYVTRHARGTVSADGLVEAFGRKLRTGVYRIGVFPDEIAEQA
KRYESRQHVLDLKQSLEGRKLIMSVDRLDYSKGLVERFRAFEHLLERSPEWRGNVTLVQIAPPTRSDVATYQKIRQDLEY
EAGRINGRYSGLDYTPIRYLNQQYDRWKLMSLFRESQIGFVTPLHDGMNLVAKEYVAAQNPDDPGVLVLSIFAGAAAELS
GALLVNPHDAIGMCEALQRALQMPLDARQRRHEINMAALRKNDLGVWRDTFLHDLRSVPVQQPGKGGGHN
>Mature_469_residues
GRLIVVSNRVATPTETKGSAGGLAVGVFGALKDAGGVWFGWSGDVVSETVANAGPTLEQDGAVTFATVGLTRKDYDQYYR
GFSNATLWPVFHYRNDLARYEREEYTGYRRVNAWLAHKLIKLLEPDDVIWIHDYHLIPFAEALRNEGVTNRIGFFLHIPF
PAPQILLNIPPHEELVKSLSCYDLLGFQTATDELAFKDYVTRHARGTVSADGLVEAFGRKLRTGVYRIGVFPDEIAEQAK
RYESRQHVLDLKQSLEGRKLIMSVDRLDYSKGLVERFRAFEHLLERSPEWRGNVTLVQIAPPTRSDVATYQKIRQDLEYE
AGRINGRYSGLDYTPIRYLNQQYDRWKLMSLFRESQIGFVTPLHDGMNLVAKEYVAAQNPDDPGVLVLSIFAGAAAELSG
ALLVNPHDAIGMCEALQRALQMPLDARQRRHEINMAALRKNDLGVWRDTFLHDLRSVPVQQPGKGGGHN

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=458, Percent_Identity=53.7117903930131, Blast_Score=467, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI115533558, Length=372, Percent_Identity=31.4516129032258, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI115533560, Length=372, Percent_Identity=31.4516129032258, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71987012, Length=431, Percent_Identity=29.6983758700696, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6319602, Length=470, Percent_Identity=34.0425531914894, Blast_Score=274, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6323537, Length=383, Percent_Identity=28.1984334203655, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6320279, Length=415, Percent_Identity=27.4698795180723, Blast_Score=163, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6323917, Length=443, Percent_Identity=25.5079006772009, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI19920676, Length=485, Percent_Identity=35.4639175257732, Blast_Score=265, Evalue=4e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 52956; Mature: 52825

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLIVVSNRVATPTETKGSAGGLAVGVFGALKDAGGVWFGWSGDVVSETVANAGPTLEQ
CCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHCCCCCCCC
DGAVTFATVGLTRKDYDQYYRGFSNATLWPVFHYRNDLARYEREEYTGYRRVNAWLAHKL
CCCEEEEEECCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IKLLEPDDVIWIHDYHLIPFAEALRNEGVTNRIGFFLHIPFPAPQILLNIPPHEELVKSL
HHHCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCEEEECCCCCCEEEEECCCHHHHHHHH
SCYDLLGFQTATDELAFKDYVTRHARGTVSADGLVEAFGRKLRTGVYRIGVFPDEIAEQA
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHHHH
KRYESRQHVLDLKQSLEGRKLIMSVDRLDYSKGLVERFRAFEHLLERSPEWRGNVTLVQI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
APPTRSDVATYQKIRQDLEYEAGRINGRYSGLDYTPIRYLNQQYDRWKLMSLFRESQIGF
CCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
VTPLHDGMNLVAKEYVAAQNPDDPGVLVLSIFAGAAAELSGALLVNPHDAIGMCEALQRA
EEECHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCHHHHCCCEEEECCCHHHHHHHHHHHH
LQMPLDARQRRHEINMAALRKNDLGVWRDTFLHDLRSVPVQQPGKGGGHN
HHCCHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
GRLIVVSNRVATPTETKGSAGGLAVGVFGALKDAGGVWFGWSGDVVSETVANAGPTLEQ
CCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHCCCCCCCC
DGAVTFATVGLTRKDYDQYYRGFSNATLWPVFHYRNDLARYEREEYTGYRRVNAWLAHKL
CCCEEEEEECCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IKLLEPDDVIWIHDYHLIPFAEALRNEGVTNRIGFFLHIPFPAPQILLNIPPHEELVKSL
HHHCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCEEEECCCCCCEEEEECCCHHHHHHHH
SCYDLLGFQTATDELAFKDYVTRHARGTVSADGLVEAFGRKLRTGVYRIGVFPDEIAEQA
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHHHH
KRYESRQHVLDLKQSLEGRKLIMSVDRLDYSKGLVERFRAFEHLLERSPEWRGNVTLVQI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
APPTRSDVATYQKIRQDLEYEAGRINGRYSGLDYTPIRYLNQQYDRWKLMSLFRESQIGF
CCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
VTPLHDGMNLVAKEYVAAQNPDDPGVLVLSIFAGAAAELSGALLVNPHDAIGMCEALQRA
EEECHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCHHHHCCCEEEECCCHHHHHHHHHHHH
LQMPLDARQRRHEINMAALRKNDLGVWRDTFLHDLRSVPVQQPGKGGGHN
HHCCHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA