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The map label for this gene is hipA [C]

Identifier: 91783534

GI number: 91783534

Start: 2394903

End: 2396195

Strand: Direct

Name: hipA [C]

Synonym: Bxe_A2281

Alternate gene names: 91783534

Gene position: 2394903-2396195 (Clockwise)

Preceding gene: 91783533

Following gene: 91783540

Centisome position: 48.92

GC content: 62.88

Gene sequence:

>1293_bases
ATGGCCGCTAGAACGCTCGTCGCCTATGCGAATGGCCGGCGCGTTGGCATCGTGAGCGATGACAGCGGTATCTGGTCATT
TACCTACGACAAGGACTGGCTCGCTCGCGAGGACGCGTTCGAGCTGTCACCCGCTTTTCCGCTTGCTGCCGGGTCTTTCG
TGGACGGTTCGAGCCAGAGGCCGGTGCAATGGTTTTTCGACAATCTCCTGCCTGAAGCGGAAATGCGTATTGCACTCGCT
CGCGAGGCCAGGGTCGAGGCGGGCGACGCCTGGGGTCTGCTCGCCTATTACGGGCGGGAGTCGGCCGGCGCCTTGACCTT
GCTTGCCGAAGGTGAACACGAGGCGTCCGGCGGTCTGCAACCTTTGTCGTACGCGAATCTGGAGGCGCGCATTCAGGCCA
TGCCGCAGCACGCGCTAACCGCCACGGCGCCCAAACGCATGTCCGCGGCAGGCGCCCAGCAGAAGCTGCTGCTGACCTTG
CGAGGCGATGCGCCGGATTACGAACTGTTCGAGCCGGTGGGAAGCGAGCCGTCCATGCATCTGCTCAAGCCCGACATGCG
GAGCACGGGCTATCCCCATTCAGCGATCAACGAATTTTTCTGCATGCGGCTGGCCCGGGCGATGGGTGTGCGCGTGCCGC
CCACGCACTTCATACGCGTGCCCTCGGCCTGCTACGTCATCGATCGTTTCGACCGTGATACGACCACTGAGCCGGCCCGG
CGCCTCCATACGGTCGACGCCATGCAGTTGTTGAACTACGACCGCAGCTTCAAATATCAGAACGCTACGGCGCAGGTGTT
AAGCGATGCCATCGAAAAAACGAGCACCCGCGCAGTGGCGCGTCTCGATGTCTTCCGATGGGCGGTCTTCAACGTCCTGA
TCGGCAACGCCGATTCGCATCTGAAAAACCTGTCGTTCTTCGTCAGTCCGCGCGGCTACATGCTGGCTCCGTTCTACGAT
CTGGTGAGCACGGTCGTCTACCATACGCCGACCTACCAGCCGCAACAGCGGGACCGTTGGCCGCATTGCGACCTGACCAT
GCCCGTTGGAGACGCCACCCGGTTCGCGGACATTTCCAGAAGGAACATGCTGGCATTCGGCGAGGCGCTTCATCTCGCGC
CAAGAGGTTCGGAAAGGTTGCTGGATGACATGCTGGCCATTCTCGACGCGCGCGTGATGGACACGCGGCGTGCCGTCGGC
GAAATCGCGCAGCCGAATGCCGGCGAGGTCCGGCTGCTCGACTCGATCGTCGCGATGCCGCTCGCGGAGATGAGCGCGGC
GCTGCGCAAGTGA

Upstream 100 bases:

>100_bases
CATCTTCTCGCTGAACTGGGCATCACGCTGCGCGCGCAAGTTTCCGTGGACATTCCTCCAGCCTCGGCCACCAAGGCGCT
CCAGCGCAGACGGACCACTC

Downstream 100 bases:

>100_bases
GCGCGGTGGTTTAACCGAGTGGTCGACCGCATATGAAAAAGGCGCTGTTCAGTCATTGACTGAACAGCGCCTTTTTCAGA
ATCGAGGACCGCCGATCACG

Product: protein related to capsule biosynthesis enzymes, HipA-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MAARTLVAYANGRRVGIVSDDSGIWSFTYDKDWLAREDAFELSPAFPLAAGSFVDGSSQRPVQWFFDNLLPEAEMRIALA
REARVEAGDAWGLLAYYGRESAGALTLLAEGEHEASGGLQPLSYANLEARIQAMPQHALTATAPKRMSAAGAQQKLLLTL
RGDAPDYELFEPVGSEPSMHLLKPDMRSTGYPHSAINEFFCMRLARAMGVRVPPTHFIRVPSACYVIDRFDRDTTTEPAR
RLHTVDAMQLLNYDRSFKYQNATAQVLSDAIEKTSTRAVARLDVFRWAVFNVLIGNADSHLKNLSFFVSPRGYMLAPFYD
LVSTVVYHTPTYQPQQRDRWPHCDLTMPVGDATRFADISRRNMLAFGEALHLAPRGSERLLDDMLAILDARVMDTRRAVG
EIAQPNAGEVRLLDSIVAMPLAEMSAALRK

Sequences:

>Translated_430_residues
MAARTLVAYANGRRVGIVSDDSGIWSFTYDKDWLAREDAFELSPAFPLAAGSFVDGSSQRPVQWFFDNLLPEAEMRIALA
REARVEAGDAWGLLAYYGRESAGALTLLAEGEHEASGGLQPLSYANLEARIQAMPQHALTATAPKRMSAAGAQQKLLLTL
RGDAPDYELFEPVGSEPSMHLLKPDMRSTGYPHSAINEFFCMRLARAMGVRVPPTHFIRVPSACYVIDRFDRDTTTEPAR
RLHTVDAMQLLNYDRSFKYQNATAQVLSDAIEKTSTRAVARLDVFRWAVFNVLIGNADSHLKNLSFFVSPRGYMLAPFYD
LVSTVVYHTPTYQPQQRDRWPHCDLTMPVGDATRFADISRRNMLAFGEALHLAPRGSERLLDDMLAILDARVMDTRRAVG
EIAQPNAGEVRLLDSIVAMPLAEMSAALRK
>Mature_429_residues
AARTLVAYANGRRVGIVSDDSGIWSFTYDKDWLAREDAFELSPAFPLAAGSFVDGSSQRPVQWFFDNLLPEAEMRIALAR
EARVEAGDAWGLLAYYGRESAGALTLLAEGEHEASGGLQPLSYANLEARIQAMPQHALTATAPKRMSAAGAQQKLLLTLR
GDAPDYELFEPVGSEPSMHLLKPDMRSTGYPHSAINEFFCMRLARAMGVRVPPTHFIRVPSACYVIDRFDRDTTTEPARR
LHTVDAMQLLNYDRSFKYQNATAQVLSDAIEKTSTRAVARLDVFRWAVFNVLIGNADSHLKNLSFFVSPRGYMLAPFYDL
VSTVVYHTPTYQPQQRDRWPHCDLTMPVGDATRFADISRRNMLAFGEALHLAPRGSERLLDDMLAILDARVMDTRRAVGE
IAQPNAGEVRLLDSIVAMPLAEMSAALRK

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4dM [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=342, Percent_Identity=30.9941520467836, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 47832; Mature: 47701

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARTLVAYANGRRVGIVSDDSGIWSFTYDKDWLAREDAFELSPAFPLAAGSFVDGSSQR
CCCCEEEEEECCCEEEEEECCCCEEEEECCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PVQWFFDNLLPEAEMRIALAREARVEAGDAWGLLAYYGRESAGALTLLAEGEHEASGGLQ
CHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEHHHHCCCCCCEEEEEECCCCCCCCCCC
PLSYANLEARIQAMPQHALTATAPKRMSAAGAQQKLLLTLRGDAPDYELFEPVGSEPSMH
CCCCCCHHHHHHHCCHHHHHHCCCHHHHHCCCCEEEEEEEECCCCCHHHHCCCCCCCCCE
LLKPDMRSTGYPHSAINEFFCMRLARAMGVRVPPTHFIRVPSACYVIDRFDRDTTTEPAR
EECCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCEEEEECCCCCCCCHHHH
RLHTVDAMQLLNYDRSFKYQNATAQVLSDAIEKTSTRAVARLDVFRWAVFNVLIGNADSH
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LKNLSFFVSPRGYMLAPFYDLVSTVVYHTPTYQPQQRDRWPHCDLTMPVGDATRFADISR
HHCCEEEECCCCCEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHH
RNMLAFGEALHLAPRGSERLLDDMLAILDARVMDTRRAVGEIAQPNAGEVRLLDSIVAMP
CCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LAEMSAALRK
HHHHHHHHCC
>Mature Secondary Structure 
AARTLVAYANGRRVGIVSDDSGIWSFTYDKDWLAREDAFELSPAFPLAAGSFVDGSSQR
CCCEEEEEECCCEEEEEECCCCEEEEECCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PVQWFFDNLLPEAEMRIALAREARVEAGDAWGLLAYYGRESAGALTLLAEGEHEASGGLQ
CHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEHHHHCCCCCCEEEEEECCCCCCCCCCC
PLSYANLEARIQAMPQHALTATAPKRMSAAGAQQKLLLTLRGDAPDYELFEPVGSEPSMH
CCCCCCHHHHHHHCCHHHHHHCCCHHHHHCCCCEEEEEEEECCCCCHHHHCCCCCCCCCE
LLKPDMRSTGYPHSAINEFFCMRLARAMGVRVPPTHFIRVPSACYVIDRFDRDTTTEPAR
EECCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCEEEEECCCCCCCCHHHH
RLHTVDAMQLLNYDRSFKYQNATAQVLSDAIEKTSTRAVARLDVFRWAVFNVLIGNADSH
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LKNLSFFVSPRGYMLAPFYDLVSTVVYHTPTYQPQQRDRWPHCDLTMPVGDATRFADISR
HHCCEEEECCCCCEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHH
RNMLAFGEALHLAPRGSERLLDDMLAILDARVMDTRRAVGEIAQPNAGEVRLLDSIVAMP
CCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LAEMSAALRK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]