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The map label for this gene is phbC [H]

Identifier: 91783473

GI number: 91783473

Start: 2317131

End: 2318936

Strand: Direct

Name: phbC [H]

Synonym: Bxe_A2343

Alternate gene names: 91783473

Gene position: 2317131-2318936 (Clockwise)

Preceding gene: 91783472

Following gene: 91783474

Centisome position: 47.33

GC content: 63.01

Gene sequence:

>1806_bases
ATGCAACAGTTATTCGACGCCTGGATGGGCGCCTGGCGTTCGCTTGGCACGCCGCCCGGCAGTAACGGCATGCCGTTCCC
CGTGCCTCAGATGCCGCAAACAGGTCTGCCGCAGATGCCGTCGTTTCCCGGCATGCCGGACTTCGCCAGACTCGCGGCCG
GATCGATGCCGGCCATGCCGTCCTTCGCCGGCCTGAACATTCCGAGCGCAGCGATTCCCTCCGAGCGACTGCAGAAACTT
CAGGCCGACTATTCGCGCGAGGCGATGGAGTTGATCCAGCAGGCCGCCACGTCCGCGACCAAAGCTCCTGAACTCAAGGA
CCGCCGCTTCAGTTCCGACGCATGGAGTTCGGCGCCGGCCTACGCATTCACCGCCGCCTGGTATTTGCTGAACGCGCGCT
ATCTGCAGGAAATGGTCGACGCGCTCGACATAGAACCCAAGGTGCGCGAGCGCATCCGTTTCGCTGTCCAGCAGTGGACG
GCGGCGGCATCGCCGAGCAACTTCTTCGCATTGAATCCCGAAGCGCAAAAAACCTTGCTGGACAGCAACGGCGAGAGCTT
GCGCCAGGGCGTGATGAACCTGCTCGGCGACTTGCAGCGCGGCAAGATTTCGCAGACCGACGAATCGCGTTTCGTGGTGG
GCGAGAACCTCGCGAACACGGAAGGCTCGGTCGTGTTCGAAAACGAGCTGATGCAGCTGATCCAGTACAAGCCGCGCACG
GCGACCGTGCGTGAGCGGCCGCTGCTCATCGTGCCGCCTTGCATCAACAAGTTCTACATTCTCGATCTGCAACCGGAGAA
TTCGCTGGTGGCCCACGGACTCGATTCGGGACACCAGGTATTCCTGATTTCGTGGCGCAATGCCGATCAATCGATCGCGC
ACAAGACGTGGGACGACTACATCGGCGAAGGCGTGCTCACCGCTATCGAGACCGTGAGCAAAATCAGCGGCCGCGAGCAG
ATCAATACGCTCGGCTTCTGCGTGGGCGGCACGATGCTGGCCACGGCGCTGGCGGTGGCCGCGGCGCGCGGCCAGCATCC
GGCCGCGTCCATGACGCTGCTCACCGCCATGCTCGATTTTTCGGACACGGGTGTGCTCGACGTATTCGTCGACGACGCGC
ATGTGAAGATGCGCGAGCAGACCATCGGCGGCAAGAACGGTACGCCGCCGGGGCTGATGCGCGGCATCGAATTCGCCAAC
ACGTTTTCGTTCCTGCGGCCGAACGATCTGGTGTGGAACTACGTCGTCGACAATTACCTCAAAGGGCGTACGCCGGTGCC
GTTCGACCTGCTGTACTGGAACAGCGACTCGACCAGCCTGCCGGGCCCGATGTATGTCTGGTATCTGCGCAATACGTACC
TCGAAAATCGTCTGCGCGAGCCGGGTGCGGTGACCACCTGCGGCGAGCCGGTCGATCTGTCGAAGATCGACGTGCCTACC
TTCATCTACGGTTCACGCGAAGACCATATCGTGCCGTGGCAAACGGCGTACGCGTCGGTGCCGTTGCTGAGCGGGCCGTT
GAAGTTCGTGCTGGGCGCGTCGGGTCACATCGCGGGCGTGATCAATCCACCCGCGAAGAAAAAGCGCAATTTCTGGATGC
TGGAAGGCGACGTCAAGACGCTGCCGGAGAACCCGGAGGAATGGCTCGATCAGGCCGCCGAAGTGCCGGGCAGCTGGTGG
CCCGAATGGACCACATGGCTCGACCAGTACGGCGGCAGGAAGGTGAAGCCACGCGCTGCTGCCGGTTCGGCCGAATTCCC
GGTGATCGAGCCGGCGCCGGGGCGCTACGTGCGGCAACGGGAGTAG

Upstream 100 bases:

>100_bases
AGGCATGGCAGCATCACATTCCTCAGCTTCCCCCAAGACGGACTCCACGACGGAGCACACGCAGCAGGCCGGTACGAGCG
GTGCAGCGCCGGCCGCAGGG

Downstream 100 bases:

>100_bases
GTTCGAGCCCGCTTCATGGCATGGCTCTTTTCGGTGTGAACGCGTAGCTGACCGGGTCAGGGCGCAAGCAGAAGGAACGA
GATTTTTTAACTTGACGGGC

Product: Poly(R)-hydroxyalkanoic acid synthase, class I

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MQQLFDAWMGAWRSLGTPPGSNGMPFPVPQMPQTGLPQMPSFPGMPDFARLAAGSMPAMPSFAGLNIPSAAIPSERLQKL
QADYSREAMELIQQAATSATKAPELKDRRFSSDAWSSAPAYAFTAAWYLLNARYLQEMVDALDIEPKVRERIRFAVQQWT
AAASPSNFFALNPEAQKTLLDSNGESLRQGVMNLLGDLQRGKISQTDESRFVVGENLANTEGSVVFENELMQLIQYKPRT
ATVRERPLLIVPPCINKFYILDLQPENSLVAHGLDSGHQVFLISWRNADQSIAHKTWDDYIGEGVLTAIETVSKISGREQ
INTLGFCVGGTMLATALAVAAARGQHPAASMTLLTAMLDFSDTGVLDVFVDDAHVKMREQTIGGKNGTPPGLMRGIEFAN
TFSFLRPNDLVWNYVVDNYLKGRTPVPFDLLYWNSDSTSLPGPMYVWYLRNTYLENRLREPGAVTTCGEPVDLSKIDVPT
FIYGSREDHIVPWQTAYASVPLLSGPLKFVLGASGHIAGVINPPAKKKRNFWMLEGDVKTLPENPEEWLDQAAEVPGSWW
PEWTTWLDQYGGRKVKPRAAAGSAEFPVIEPAPGRYVRQRE

Sequences:

>Translated_601_residues
MQQLFDAWMGAWRSLGTPPGSNGMPFPVPQMPQTGLPQMPSFPGMPDFARLAAGSMPAMPSFAGLNIPSAAIPSERLQKL
QADYSREAMELIQQAATSATKAPELKDRRFSSDAWSSAPAYAFTAAWYLLNARYLQEMVDALDIEPKVRERIRFAVQQWT
AAASPSNFFALNPEAQKTLLDSNGESLRQGVMNLLGDLQRGKISQTDESRFVVGENLANTEGSVVFENELMQLIQYKPRT
ATVRERPLLIVPPCINKFYILDLQPENSLVAHGLDSGHQVFLISWRNADQSIAHKTWDDYIGEGVLTAIETVSKISGREQ
INTLGFCVGGTMLATALAVAAARGQHPAASMTLLTAMLDFSDTGVLDVFVDDAHVKMREQTIGGKNGTPPGLMRGIEFAN
TFSFLRPNDLVWNYVVDNYLKGRTPVPFDLLYWNSDSTSLPGPMYVWYLRNTYLENRLREPGAVTTCGEPVDLSKIDVPT
FIYGSREDHIVPWQTAYASVPLLSGPLKFVLGASGHIAGVINPPAKKKRNFWMLEGDVKTLPENPEEWLDQAAEVPGSWW
PEWTTWLDQYGGRKVKPRAAAGSAEFPVIEPAPGRYVRQRE
>Mature_601_residues
MQQLFDAWMGAWRSLGTPPGSNGMPFPVPQMPQTGLPQMPSFPGMPDFARLAAGSMPAMPSFAGLNIPSAAIPSERLQKL
QADYSREAMELIQQAATSATKAPELKDRRFSSDAWSSAPAYAFTAAWYLLNARYLQEMVDALDIEPKVRERIRFAVQQWT
AAASPSNFFALNPEAQKTLLDSNGESLRQGVMNLLGDLQRGKISQTDESRFVVGENLANTEGSVVFENELMQLIQYKPRT
ATVRERPLLIVPPCINKFYILDLQPENSLVAHGLDSGHQVFLISWRNADQSIAHKTWDDYIGEGVLTAIETVSKISGREQ
INTLGFCVGGTMLATALAVAAARGQHPAASMTLLTAMLDFSDTGVLDVFVDDAHVKMREQTIGGKNGTPPGLMRGIEFAN
TFSFLRPNDLVWNYVVDNYLKGRTPVPFDLLYWNSDSTSLPGPMYVWYLRNTYLENRLREPGAVTTCGEPVDLSKIDVPT
FIYGSREDHIVPWQTAYASVPLLSGPLKFVLGASGHIAGVINPPAKKKRNFWMLEGDVKTLPENPEEWLDQAAEVPGSWW
PEWTTWLDQYGGRKVKPRAAAGSAEFPVIEPAPGRYVRQRE

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 66559; Mature: 66559

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLFDAWMGAWRSLGTPPGSNGMPFPVPQMPQTGLPQMPSFPGMPDFARLAAGSMPAMP
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCC
SFAGLNIPSAAIPSERLQKLQADYSREAMELIQQAATSATKAPELKDRRFSSDAWSSAPA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCC
YAFTAAWYLLNARYLQEMVDALDIEPKVRERIRFAVQQWTAAASPSNFFALNPEAQKTLL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHH
DSNGESLRQGVMNLLGDLQRGKISQTDESRFVVGENLANTEGSVVFENELMQLIQYKPRT
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHCCCCC
ATVRERPLLIVPPCINKFYILDLQPENSLVAHGLDSGHQVFLISWRNADQSIAHKTWDDY
CCCCCCCEEEECCCCCCEEEEEECCCCCCEECCCCCCCEEEEEEECCCCHHHHHHHHHHH
IGEGVLTAIETVSKISGREQINTLGFCVGGTMLATALAVAAARGQHPAASMTLLTAMLDF
HCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
SDTGVLDVFVDDAHVKMREQTIGGKNGTPPGLMRGIEFANTFSFLRPNDLVWNYVVDNYL
CCCCEEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
KGRTPVPFDLLYWNSDSTSLPGPMYVWYLRNTYLENRLREPGAVTTCGEPVDLSKIDVPT
CCCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCE
FIYGSREDHIVPWQTAYASVPLLSGPLKFVLGASGHIAGVINPPAKKKRNFWMLEGDVKT
EEECCCCCCCCCCHHHHHCCCCCCCCHHHHCCCCCCEEEEECCCHHHCCCEEEEECCCCC
LPENPEEWLDQAAEVPGSWWPEWTTWLDQYGGRKVKPRAAAGSAEFPVIEPAPGRYVRQR
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCEECCCCCCCCCCC
E
C
>Mature Secondary Structure
MQQLFDAWMGAWRSLGTPPGSNGMPFPVPQMPQTGLPQMPSFPGMPDFARLAAGSMPAMP
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCC
SFAGLNIPSAAIPSERLQKLQADYSREAMELIQQAATSATKAPELKDRRFSSDAWSSAPA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCC
YAFTAAWYLLNARYLQEMVDALDIEPKVRERIRFAVQQWTAAASPSNFFALNPEAQKTLL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHH
DSNGESLRQGVMNLLGDLQRGKISQTDESRFVVGENLANTEGSVVFENELMQLIQYKPRT
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCEEEHHHHHHHHHCCCCC
ATVRERPLLIVPPCINKFYILDLQPENSLVAHGLDSGHQVFLISWRNADQSIAHKTWDDY
CCCCCCCEEEECCCCCCEEEEEECCCCCCEECCCCCCCEEEEEEECCCCHHHHHHHHHHH
IGEGVLTAIETVSKISGREQINTLGFCVGGTMLATALAVAAARGQHPAASMTLLTAMLDF
HCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
SDTGVLDVFVDDAHVKMREQTIGGKNGTPPGLMRGIEFANTFSFLRPNDLVWNYVVDNYL
CCCCEEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
KGRTPVPFDLLYWNSDSTSLPGPMYVWYLRNTYLENRLREPGAVTTCGEPVDLSKIDVPT
CCCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCE
FIYGSREDHIVPWQTAYASVPLLSGPLKFVLGASGHIAGVINPPAKKKRNFWMLEGDVKT
EEECCCCCCCCCCHHHHHCCCCCCCCHHHHCCCCCCEEEEECCCHHHCCCEEEEECCCCC
LPENPEEWLDQAAEVPGSWWPEWTTWLDQYGGRKVKPRAAAGSAEFPVIEPAPGRYVRQR
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEECCCCCCCCCCCCEECCCCCCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2670936; 1987116 [H]