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The map label for this gene is clpB [H]

Identifier: 91783442

GI number: 91783442

Start: 2282237

End: 2284834

Strand: Direct

Name: clpB [H]

Synonym: Bxe_A2374

Alternate gene names: 91783442

Gene position: 2282237-2284834 (Clockwise)

Preceding gene: 91783441

Following gene: 91783445

Centisome position: 46.62

GC content: 61.78

Gene sequence:

>2598_bases
ATGAGAATCGACAAACTCACCACTAAATTCCAGGAAGCACTGGCCGATGCCCAAAGTCTGGCTGTCGGCCACGACAATCA
ATACATCGAACCGGTTCACGTCCTGTCGGCGCTCGTCGCCCAACAGGATGGCTCGGCGCGTTCGCTGCTCTCGCGTGCCG
GCGTGCATGTGCAGGCGCTGCAAACGGCGCTCGGCGACGCCATCACGCGTCTGCCGCAAGTGCAAGGCACCGACGGCAAC
GTGCAGATCGGCCGCGATCTGACCGGCCTCCTGAACCAGGCCGACAAGGAAGCGCAAAAACTCAACGACACGTTCATCGC
GAGCGAGATGTTCCTGCTCGCCGTCGCGGACGACAAAGGCGAAGCCGGCCGTCTGGCGCGTCAGCATGGCTTGTCGCGCA
AGTCGCTGGAAAGCGCGATCGCCGCGGTGCGCGGCGGTTCGCAGGTGCATAGCCAGGACGCGGAAAGCCAGCGTGAGGCG
CTGAAGAAATACACCGTGGATCTGACCGAGCGCGCGCGGGCCGGCAAGCTCGATCCGGTGATCGGCCGCGACGACGAAAT
CCGTCGCTCGATCCAGATCCTGCAACGCCGCACCAAGAACAACCCTGTGCTGATCGGCGAACCGGGCGTGGGTAAGACCG
CGATCGTCGAAGGTCTGGCGCAGCGTATCGTCAACGGCGAAGTGCCGGAGACGCTCAAGGGCAAGCGCGTGCTGTCGCTC
GATATGGCGGCGTTGCTGGCCGGCGCCAAGTATCGCGGCGAATTCGAAGAACGCCTGAAGGCCGTGCTGAACGACATCGC
GAAAGACGAAGGCCAGACCATCGTCTTCATCGACGAAATTCACACTATGGTCGGTGCGGGCAAGGCCGAAGGCGCGATGG
ACGCGGGCAACATGCTCAAGCCGGCGCTCTCGCGCGGCGAGCTGCATTGCGTCGGCGCGACCACGCTCGATGAATATCGC
AAGTACATCGAAAAGGACGCCGCGCTCGAACGCCGCTTCCAGAAGGTGCTGGTCGACGAACCGACGGTCGAAGCCACCAT
CGCGATCCTGCGCGGTCTGCAGGAAAAGTACGAGCTGCACCACGGCGTGGATATCACCGACCCGGCGATCGTGGCGGCGG
CTGAACTGTCGCATCGCTACATCACGGATCGGTTCCTGCCGGACAAGGCCATCGACCTGATCGACGAAGCCGCTTCGAAG
ATCAAGATGGAAATCGATTCGAAGCCGGAAGAGATGGATCGGCTCGACCGTCGTTTGATCCAGTTGAAGATTGAGCGCGA
AGCCGTCAAGAAGGAAAAAGACGAAGCGTCGCAGAAGCGTCTGCAACTGATCGAGGAAGAAATCGAGCGGCTGAACCGCG
AATATTCGGACCTCGACGAAATCTGGACCGCGGAAAAAGCCGCGGTGCAAGGCAGCGCGCAACTGAAGGAAGAGATCGAA
AAAACGCGTGCGGAAATCACGCGCCTGCAACGTGAAGGCAAGCTCGAGAAGGTCGCCGAGTTGCAGTACGGCAAGCTGCC
GGGACTCGAAGCGCAGTTGAAGGAAGTGACCAAGGCCGAGGCGAGCGAGCAGAACAATCCGACGCGCCCGCGCCTCTTGC
GCACGCAGGTCGGTGCGGAAGAAATCGCTGAAGTCGTGTCGCGCGCCACCGGCATTCCCGTGTCGCGCATGATGCAGGGC
GAGCGCGAAAAGCTGCTGCAGATCGAAGAGAAGCTGCACGCGCGCGTGGTCGGCCAGGACGAGGCGATCAGCGCGGTGGC
CGATGCGATCCGCCGCTCGCGTGCGGGTCTGTCGGATCCGAACCGGCCGTATGGTTCGTTCCTGTTCCTCGGCCCGACCG
GCGTGGGCAAGACCGAGTTGTGCAAGGCGCTCGCGTCGTTCCTGTTCGATTCGGAAGATCATCTGATCCGTATCGACATG
AGCGAATTCATGGAGAAGCATAGCGTCGCGCGTCTGATCGGTGCGCCGCCGGGATACGTCGGCTACGAAGAGGGTGGATA
CCTGACCGAAGCCGTGCGTCGCAAGCCGTATAGCGTGATCCTGCTCGACGAAATCGAGAAGGCGCATCCGGACGTGTTCA
ACGTGCTGCTGCAAGTGCTCGACGACGGCCGCATGACCGACGGCCAGGGCCGTACCGTGGACTTCAAGAACACGGTGATC
GTGATGACGTCGAACCTCGGTTCGCAGGTGATCCAGGCAATGGTCGGCGAACCGCAGGAAGCCGTGAAGGACGCGGTCTG
GGAAGAAGTGAAGCTGCACTTCCGGCCCGAGTTCCTGAACCGGATCGACGACGTGGTGGTGTTCCATGCACTCGACCGTT
CGAACATCCAGTCGATCGCGCGGATCCAGTTGCAGCGTCTGCAGGAGCGGCTCGCCAAGCTCGATATGCAATTGCTGGTG
TCGGACGAGGCGCTCGAACACGTCGGCAAGGTCGGCTACGATCCGCTGTTCGGTGCGCGGCCGTTGAAGCGCGCCATCCA
GCAGGAAATCGAGAATCCGGTCGCCAAGCTGATTCTGGCCGGCAAGTTCGGTCCGAAAGACGTGATTCCGGTCGAAGTGG
AAGACGGCAAACTGGTGTTTGAACGCGTCGTGCATTAA

Upstream 100 bases:

>100_bases
TTGCGTCAAATGTCAAATATTCGTCGCCTGATGCAAAAAAGCGCTTGAAACCTGGATAAAACACCTCATTTTGGTGGTAA
TCGAAATTGGAGGTCTCTTG

Downstream 100 bases:

>100_bases
CAGGACGCGCTCGGCGAGGACGGAACGGCAGCGTTCGAGCCGTTCCCGCCGAAGTAAAAAACCGGCAACGAAGGTGACTT
CGTTGCCGGTTTTTTTTGCC

Product: heat-shock protein, chaperone ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 865; Mature: 865

Protein sequence:

>865_residues
MRIDKLTTKFQEALADAQSLAVGHDNQYIEPVHVLSALVAQQDGSARSLLSRAGVHVQALQTALGDAITRLPQVQGTDGN
VQIGRDLTGLLNQADKEAQKLNDTFIASEMFLLAVADDKGEAGRLARQHGLSRKSLESAIAAVRGGSQVHSQDAESQREA
LKKYTVDLTERARAGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCVGATTLDEYR
KYIEKDAALERRFQKVLVDEPTVEATIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPEEMDRLDRRLIQLKIEREAVKKEKDEASQKRLQLIEEEIERLNREYSDLDEIWTAEKAAVQGSAQLKEEIE
KTRAEITRLQREGKLEKVAELQYGKLPGLEAQLKEVTKAEASEQNNPTRPRLLRTQVGAEEIAEVVSRATGIPVSRMMQG
EREKLLQIEEKLHARVVGQDEAISAVADAIRRSRAGLSDPNRPYGSFLFLGPTGVGKTELCKALASFLFDSEDHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQVIQAMVGEPQEAVKDAVWEEVKLHFRPEFLNRIDDVVVFHALDRSNIQSIARIQLQRLQERLAKLDMQLLV
SDEALEHVGKVGYDPLFGARPLKRAIQQEIENPVAKLILAGKFGPKDVIPVEVEDGKLVFERVVH

Sequences:

>Translated_865_residues
MRIDKLTTKFQEALADAQSLAVGHDNQYIEPVHVLSALVAQQDGSARSLLSRAGVHVQALQTALGDAITRLPQVQGTDGN
VQIGRDLTGLLNQADKEAQKLNDTFIASEMFLLAVADDKGEAGRLARQHGLSRKSLESAIAAVRGGSQVHSQDAESQREA
LKKYTVDLTERARAGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCVGATTLDEYR
KYIEKDAALERRFQKVLVDEPTVEATIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPEEMDRLDRRLIQLKIEREAVKKEKDEASQKRLQLIEEEIERLNREYSDLDEIWTAEKAAVQGSAQLKEEIE
KTRAEITRLQREGKLEKVAELQYGKLPGLEAQLKEVTKAEASEQNNPTRPRLLRTQVGAEEIAEVVSRATGIPVSRMMQG
EREKLLQIEEKLHARVVGQDEAISAVADAIRRSRAGLSDPNRPYGSFLFLGPTGVGKTELCKALASFLFDSEDHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQVIQAMVGEPQEAVKDAVWEEVKLHFRPEFLNRIDDVVVFHALDRSNIQSIARIQLQRLQERLAKLDMQLLV
SDEALEHVGKVGYDPLFGARPLKRAIQQEIENPVAKLILAGKFGPKDVIPVEVEDGKLVFERVVH
>Mature_865_residues
MRIDKLTTKFQEALADAQSLAVGHDNQYIEPVHVLSALVAQQDGSARSLLSRAGVHVQALQTALGDAITRLPQVQGTDGN
VQIGRDLTGLLNQADKEAQKLNDTFIASEMFLLAVADDKGEAGRLARQHGLSRKSLESAIAAVRGGSQVHSQDAESQREA
LKKYTVDLTERARAGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCVGATTLDEYR
KYIEKDAALERRFQKVLVDEPTVEATIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPEEMDRLDRRLIQLKIEREAVKKEKDEASQKRLQLIEEEIERLNREYSDLDEIWTAEKAAVQGSAQLKEEIE
KTRAEITRLQREGKLEKVAELQYGKLPGLEAQLKEVTKAEASEQNNPTRPRLLRTQVGAEEIAEVVSRATGIPVSRMMQG
EREKLLQIEEKLHARVVGQDEAISAVADAIRRSRAGLSDPNRPYGSFLFLGPTGVGKTELCKALASFLFDSEDHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQVIQAMVGEPQEAVKDAVWEEVKLHFRPEFLNRIDDVVVFHALDRSNIQSIARIQLQRLQERLAKLDMQLLV
SDEALEHVGKVGYDPLFGARPLKRAIQQEIENPVAKLILAGKFGPKDVIPVEVEDGKLVFERVVH

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=298, Percent_Identity=36.9127516778523, Blast_Score=202, Evalue=2e-51,
Organism=Escherichia coli, GI1788943, Length=860, Percent_Identity=66.9767441860465, Blast_Score=1176, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=419, Percent_Identity=40.3341288782816, Blast_Score=283, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6320464, Length=712, Percent_Identity=53.2303370786517, Blast_Score=761, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=865, Percent_Identity=42.4277456647399, Blast_Score=690, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96058; Mature: 96058

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDKLTTKFQEALADAQSLAVGHDNQYIEPVHVLSALVAQQDGSARSLLSRAGVHVQAL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHH
QTALGDAITRLPQVQGTDGNVQIGRDLTGLLNQADKEAQKLNDTFIASEMFLLAVADDKG
HHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCC
EAGRLARQHGLSRKSLESAIAAVRGGSQVHSQDAESQREALKKYTVDLTERARAGKLDPV
CHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHCCCEEHHH
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALSRGELHCVGATTLDEYRKYIEKDAALERRFQKVLVDEPTVEATIAILRGLQEKYELH
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
HGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASKIKMEIDSKPEEMDRLDRRLI
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCCCHHHHHHHHHHHH
QLKIEREAVKKEKDEASQKRLQLIEEEIERLNREYSDLDEIWTAEKAAVQGSAQLKEEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KTRAEITRLQREGKLEKVAELQYGKLPGLEAQLKEVTKAEASEQNNPTRPRLLRTQVGAE
HHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHH
EIAEVVSRATGIPVSRMMQGEREKLLQIEEKLHARVVGQDEAISAVADAIRRSRAGLSDP
HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
NRPYGSFLFLGPTGVGKTELCKALASFLFDSEDHLIRIDMSEFMEKHSVARLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
VMTSNLGSQVIQAMVGEPQEAVKDAVWEEVKLHFRPEFLNRIDDVVVFHALDRSNIQSIA
EEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
RIQLQRLQERLAKLDMQLLVSDEALEHVGKVGYDPLFGARPLKRAIQQEIENPVAKLILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GKFGPKDVIPVEVEDGKLVFERVVH
CCCCCCCCEEEEECCCHHHHHHHCC
>Mature Secondary Structure
MRIDKLTTKFQEALADAQSLAVGHDNQYIEPVHVLSALVAQQDGSARSLLSRAGVHVQAL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHH
QTALGDAITRLPQVQGTDGNVQIGRDLTGLLNQADKEAQKLNDTFIASEMFLLAVADDKG
HHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCC
EAGRLARQHGLSRKSLESAIAAVRGGSQVHSQDAESQREALKKYTVDLTERARAGKLDPV
CHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHCCCEEHHH
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALSRGELHCVGATTLDEYRKYIEKDAALERRFQKVLVDEPTVEATIAILRGLQEKYELH
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
HGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASKIKMEIDSKPEEMDRLDRRLI
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCCCHHHHHHHHHHHH
QLKIEREAVKKEKDEASQKRLQLIEEEIERLNREYSDLDEIWTAEKAAVQGSAQLKEEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KTRAEITRLQREGKLEKVAELQYGKLPGLEAQLKEVTKAEASEQNNPTRPRLLRTQVGAE
HHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHH
EIAEVVSRATGIPVSRMMQGEREKLLQIEEKLHARVVGQDEAISAVADAIRRSRAGLSDP
HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
NRPYGSFLFLGPTGVGKTELCKALASFLFDSEDHLIRIDMSEFMEKHSVARLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
VMTSNLGSQVIQAMVGEPQEAVKDAVWEEVKLHFRPEFLNRIDDVVVFHALDRSNIQSIA
EEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
RIQLQRLQERLAKLDMQLLVSDEALEHVGKVGYDPLFGARPLKRAIQQEIENPVAKLILA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GKFGPKDVIPVEVEDGKLVFERVVH
CCCCCCCCEEEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]