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The map label for this gene is moaE [H]

Identifier: 91783439

GI number: 91783439

Start: 2280027

End: 2280503

Strand: Direct

Name: moaE [H]

Synonym: Bxe_A2377

Alternate gene names: 91783439

Gene position: 2280027-2280503 (Clockwise)

Preceding gene: 91783438

Following gene: 91783441

Centisome position: 46.57

GC content: 64.57

Gene sequence:

>477_bases
ATGCCCGTTCGTGTCCAGACGGAAGACTTCGACCTCACCGCCGAGGTCGCCGGATTGCGCGCGCGCAACCCGAAGATCGG
CGCGGTCGCCTGTTTTGTCGGCACCGTGCGCGACCTGAACGACGGCAGCATGATCGAGACGATGGAGCTCGAACACTATC
CCGGCATGACGGAGAAGTCGCTGGAGGCGATTATCGTCAGCGCGCGTGAACGCTGGCCGGGCATCGAGGTGCTGATCGTG
CACCGGGTCGGCAAGCTGTATCCGCTCGATCAGATCGTGCTGGTGGCGACGACGGCCGCGCATCGCGGGGAAGCCTTCGC
GTCGTGCGAATTCGTGATGGATTATCTGAAGACCCAGGCGCCGTTCTGGAAGAAAGAGAAGACCGAGGCCGGCGAGCGCT
GGGTCGACGCCCGTGTCACCGACGACGCGGCACTCGCCCGCTGGGGCATCGAATCGGACAATCGGACGGTGGAGTAG

Upstream 100 bases:

>100_bases
CGGCGCCGGCACGCGCGTCACCGAGGGCTGCGAAGTCGCGTTCTTTCCGCCCGTCACCGGCGGCTGAGCCGCCACGCAGC
TAACCGTACAGGAGCCGCAG

Downstream 100 bases:

>100_bases
GCGTGGCGGGGTTGCGGCATGATGGGAGTCAGCAGGCGTTTCTGGCGCTCTCAAACGGTTCTGAAGCGCGCCTGGCACCC
CACGGCATCTCCGCATCTTG

Product: molybdopterin synthase subunit MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MPVRVQTEDFDLTAEVAGLRARNPKIGAVACFVGTVRDLNDGSMIETMELEHYPGMTEKSLEAIIVSARERWPGIEVLIV
HRVGKLYPLDQIVLVATTAAHRGEAFASCEFVMDYLKTQAPFWKKEKTEAGERWVDARVTDDAALARWGIESDNRTVE

Sequences:

>Translated_158_residues
MPVRVQTEDFDLTAEVAGLRARNPKIGAVACFVGTVRDLNDGSMIETMELEHYPGMTEKSLEAIIVSARERWPGIEVLIV
HRVGKLYPLDQIVLVATTAAHRGEAFASCEFVMDYLKTQAPFWKKEKTEAGERWVDARVTDDAALARWGIESDNRTVE
>Mature_157_residues
PVRVQTEDFDLTAEVAGLRARNPKIGAVACFVGTVRDLNDGSMIETMELEHYPGMTEKSLEAIIVSARERWPGIEVLIVH
RVGKLYPLDQIVLVATTAAHRGEAFASCEFVMDYLKTQAPFWKKEKTEAGERWVDARVTDDAALARWGIESDNRTVE

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=113, Percent_Identity=32.7433628318584, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1787003, Length=144, Percent_Identity=49.3055555555556, Blast_Score=148, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17509279, Length=127, Percent_Identity=29.9212598425197, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356259, Length=101, Percent_Identity=36.6336633663366, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17693; Mature: 17562

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVRVQTEDFDLTAEVAGLRARNPKIGAVACFVGTVRDLNDGSMIETMELEHYPGMTEKS
CCCEECCCCCCEEHHHHCCCCCCCCCEEEEEEEHHHHCCCCCCEEEEEECCCCCCCCHHH
LEAIIVSARERWPGIEVLIVHRVGKLYPLDQIVLVATTAAHRGEAFASCEFVMDYLKTQA
HHHHHEEHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCC
PFWKKEKTEAGERWVDARVTDDAALARWGIESDNRTVE
CCCCCHHCCCCHHEECCCCCCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PVRVQTEDFDLTAEVAGLRARNPKIGAVACFVGTVRDLNDGSMIETMELEHYPGMTEKS
CCEECCCCCCEEHHHHCCCCCCCCCEEEEEEEHHHHCCCCCCEEEEEECCCCCCCCHHH
LEAIIVSARERWPGIEVLIVHRVGKLYPLDQIVLVATTAAHRGEAFASCEFVMDYLKTQA
HHHHHEEHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCC
PFWKKEKTEAGERWVDARVTDDAALARWGIESDNRTVE
CCCCCHHCCCCHHEECCCCCCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]