Click here to switch to the map view.

The map label for this gene is aer [H]

Identifier: 91783410

GI number: 91783410

Start: 2249809

End: 2251353

Strand: Direct

Name: aer [H]

Synonym: Bxe_A2405

Alternate gene names: 91783410

Gene position: 2249809-2251353 (Clockwise)

Preceding gene: 91783405

Following gene: 91783411

Centisome position: 45.95

GC content: 60.13

Gene sequence:

>1545_bases
ATGCGTAATAACCAACCCATTACCCAGCAGGAATTCGAGTTTCCTGACAATGCAACGCTGATGTCGACAACCGACACAGA
GAGTTACGTCACCTACGCCAACGCCGCATTCATGCAGGTGAGCGGTTTTTCCCTTGAAGAAATCCAGGGACAGCCCCACA
ACGTCGTGCGGCATCCGGACATGCCGAAAGAGGCGTTTGCCGACATGTGGTCGACGCTTAAAGGGGGCGAGCCGTGGTCC
GCTCTGGTCAAGAACCGGCGCAAGAACGGCGATCACTACTGGGTCCGTGCCAACGCGACGCCGGTAGTGCGTAACGGACA
ACCGGCGGGATACATGTCAGTGCGAACCCAGGCCTCACGCGAGGAGATCGTGGCGGCGGAGGCACTTTACCGGGATTTCC
GCGAAGGCAAAGCGGGCAACCGCCGTTTCCACAAGGGGCTGATTGTCCGGACAGGGCTCATGGGCTGGACCTCAGTGCTT
CAGACGATGCCTGTACGCTGGAGAATCCGCTCGGCTTTGCTCACGCTTGCACCTGCGGTCGTTCTGGCTGCGTGGCTGCT
GGGACTGAGAGGTGTCGCAGCCGCGGGCTTCGCGGGCGTATGCGCAGTGGTTTCGATGCTTGCATCGTTGTGGCTCGAAG
CACAGATTTCGCGCCCCCTCGAGCAGGTTCTCGAACAGGCCCTGCGTGTAGCGTCGGGTGAAAGCCAGAAGGCCGTCCAC
ATGAATCGTGTAGACGAAATCGGTATGACCTTGCGTACGATCAGTCAGCTTGGGTTGATGTTTCGCTGGCTGATCGACGA
TGTCAGCGGACAGGTGATCAATGTACAGACGGCAAGCAACGAGATCGCACAGGGCAACCACGACCTGAGCGTTCGCACTG
AGCAGGCCGCATCGAACGTGCAGCAGACAGCGGCATCAATGACGCAGATGACCGCCACCGTCAAGAGCAACGCGAAGACG
GCCGTCCATGCCAATCAACTCTCGGGTACAGCGCGCGACGCGGCCGCTGAGGGCGGGAGGGCCGTATCGGAAGTCGTCAG
CACGATGAACGAGATCACGGAGAGTTCGAGAAAGATTGCCGACATCATCGGCGTGATCGACGGAATCGCCTTCCAGACAA
ATATTCTCGCGCTCAACGCGGCCGTTGAGGCTGCGCGCGCAGGCGATCAGGGGCGCGGCTTTGCCGTTGTTGCTGGTGAG
GTGCGAGCGTTAGCGCAGCGTAGTGCCAACGCGGCCAAGGAGATCAAAAATCTGATCGGCGTGAGCGTGGAGAAAGTCGA
GTCCGGCTCCAGACTGGTCGATGACGCCGGCAAGACGATGGACGACATCGTAGCGCAAGTGAAGCGGGTATCGGACCTGA
TCGCGGAGATCAGTTCGGCAACTGAGGAACAGAGTAGCGGCGTGACCCAGGTCGATCAGGCGGTCAGCGAGCTCGACCAT
ATCACGCAACAGAACGCGGCCCTCGTCGAGCAAAGCACTGCGGCTTCCGAAAGCCTCAAGCAGCAGGCGACCCGGCTGGT
GAACGCAGTGAGCGTTTTCCGGTGA

Upstream 100 bases:

>100_bases
GTTATCACAAGAAGACTGCGGTGTTGTCAAATCGATTTGACGTGTTCGCTGTTCATAAAACCAGAATCGGACATCCGATC
CGCCTTCCGAGGGCCGTAAT

Downstream 100 bases:

>100_bases
TGCGCCGTGCATGGGAACTAGTCACATGATCGCCCTTAAGCCCTTCTGGAAGATTTCTTGCCAGTGGTTGGGGAAGGTGG
GTAGCCAACCAGATTTATCT

Product: methyl-accepting chemotaxis sensory transducer, Pas/Pac sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MRNNQPITQQEFEFPDNATLMSTTDTESYVTYANAAFMQVSGFSLEEIQGQPHNVVRHPDMPKEAFADMWSTLKGGEPWS
ALVKNRRKNGDHYWVRANATPVVRNGQPAGYMSVRTQASREEIVAAEALYRDFREGKAGNRRFHKGLIVRTGLMGWTSVL
QTMPVRWRIRSALLTLAPAVVLAAWLLGLRGVAAAGFAGVCAVVSMLASLWLEAQISRPLEQVLEQALRVASGESQKAVH
MNRVDEIGMTLRTISQLGLMFRWLIDDVSGQVINVQTASNEIAQGNHDLSVRTEQAASNVQQTAASMTQMTATVKSNAKT
AVHANQLSGTARDAAAEGGRAVSEVVSTMNEITESSRKIADIIGVIDGIAFQTNILALNAAVEAARAGDQGRGFAVVAGE
VRALAQRSANAAKEIKNLIGVSVEKVESGSRLVDDAGKTMDDIVAQVKRVSDLIAEISSATEEQSSGVTQVDQAVSELDH
ITQQNAALVEQSTAASESLKQQATRLVNAVSVFR

Sequences:

>Translated_514_residues
MRNNQPITQQEFEFPDNATLMSTTDTESYVTYANAAFMQVSGFSLEEIQGQPHNVVRHPDMPKEAFADMWSTLKGGEPWS
ALVKNRRKNGDHYWVRANATPVVRNGQPAGYMSVRTQASREEIVAAEALYRDFREGKAGNRRFHKGLIVRTGLMGWTSVL
QTMPVRWRIRSALLTLAPAVVLAAWLLGLRGVAAAGFAGVCAVVSMLASLWLEAQISRPLEQVLEQALRVASGESQKAVH
MNRVDEIGMTLRTISQLGLMFRWLIDDVSGQVINVQTASNEIAQGNHDLSVRTEQAASNVQQTAASMTQMTATVKSNAKT
AVHANQLSGTARDAAAEGGRAVSEVVSTMNEITESSRKIADIIGVIDGIAFQTNILALNAAVEAARAGDQGRGFAVVAGE
VRALAQRSANAAKEIKNLIGVSVEKVESGSRLVDDAGKTMDDIVAQVKRVSDLIAEISSATEEQSSGVTQVDQAVSELDH
ITQQNAALVEQSTAASESLKQQATRLVNAVSVFR
>Mature_514_residues
MRNNQPITQQEFEFPDNATLMSTTDTESYVTYANAAFMQVSGFSLEEIQGQPHNVVRHPDMPKEAFADMWSTLKGGEPWS
ALVKNRRKNGDHYWVRANATPVVRNGQPAGYMSVRTQASREEIVAAEALYRDFREGKAGNRRFHKGLIVRTGLMGWTSVL
QTMPVRWRIRSALLTLAPAVVLAAWLLGLRGVAAAGFAGVCAVVSMLASLWLEAQISRPLEQVLEQALRVASGESQKAVH
MNRVDEIGMTLRTISQLGLMFRWLIDDVSGQVINVQTASNEIAQGNHDLSVRTEQAASNVQQTAASMTQMTATVKSNAKT
AVHANQLSGTARDAAAEGGRAVSEVVSTMNEITESSRKIADIIGVIDGIAFQTNILALNAAVEAARAGDQGRGFAVVAGE
VRALAQRSANAAKEIKNLIGVSVEKVESGSRLVDDAGKTMDDIVAQVKRVSDLIAEISSATEEQSSGVTQVDQAVSELDH
ITQQNAALVEQSTAASESLKQQATRLVNAVSVFR

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=514, Percent_Identity=54.6692607003891, Blast_Score=560, Evalue=1e-161,
Organism=Escherichia coli, GI1788195, Length=303, Percent_Identity=55.1155115511551, Blast_Score=271, Evalue=7e-74,
Organism=Escherichia coli, GI2367378, Length=317, Percent_Identity=51.1041009463722, Blast_Score=268, Evalue=5e-73,
Organism=Escherichia coli, GI1787690, Length=326, Percent_Identity=48.4662576687117, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1788194, Length=317, Percent_Identity=50.788643533123, Blast_Score=265, Evalue=7e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 55441; Mature: 55441

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNNQPITQQEFEFPDNATLMSTTDTESYVTYANAAFMQVSGFSLEEIQGQPHNVVRHPD
CCCCCCCCHHHCCCCCCCEEEECCCCCHHHHHHHHHHEEECCCCHHHHCCCCCCCCCCCC
MPKEAFADMWSTLKGGEPWSALVKNRRKNGDHYWVRANATPVVRNGQPAGYMSVRTQASR
CCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHH
EEIVAAEALYRDFREGKAGNRRFHKGLIVRTGLMGWTSVLQTMPVRWRIRSALLTLAPAV
HHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLAAWLLGLRGVAAAGFAGVCAVVSMLASLWLEAQISRPLEQVLEQALRVASGESQKAVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
MNRVDEIGMTLRTISQLGLMFRWLIDDVSGQVINVQTASNEIAQGNHDLSVRTEQAASNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHCCCCCCEEEHHHHHHHH
QQTAASMTQMTATVKSNAKTAVHANQLSGTARDAAAEGGRAVSEVVSTMNEITESSRKIA
HHHHHHHHHHHHHHHCCCCHHEEHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DIIGVIDGIAFQTNILALNAAVEAARAGDQGRGFAVVAGEVRALAQRSANAAKEIKNLIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHC
VSVEKVESGSRLVDDAGKTMDDIVAQVKRVSDLIAEISSATEEQSSGVTQVDQAVSELDH
CCHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ITQQNAALVEQSTAASESLKQQATRLVNAVSVFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRNNQPITQQEFEFPDNATLMSTTDTESYVTYANAAFMQVSGFSLEEIQGQPHNVVRHPD
CCCCCCCCHHHCCCCCCCEEEECCCCCHHHHHHHHHHEEECCCCHHHHCCCCCCCCCCCC
MPKEAFADMWSTLKGGEPWSALVKNRRKNGDHYWVRANATPVVRNGQPAGYMSVRTQASR
CCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHH
EEIVAAEALYRDFREGKAGNRRFHKGLIVRTGLMGWTSVLQTMPVRWRIRSALLTLAPAV
HHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLAAWLLGLRGVAAAGFAGVCAVVSMLASLWLEAQISRPLEQVLEQALRVASGESQKAVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
MNRVDEIGMTLRTISQLGLMFRWLIDDVSGQVINVQTASNEIAQGNHDLSVRTEQAASNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHCCCCCCEEEHHHHHHHH
QQTAASMTQMTATVKSNAKTAVHANQLSGTARDAAAEGGRAVSEVVSTMNEITESSRKIA
HHHHHHHHHHHHHHHCCCCHHEEHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DIIGVIDGIAFQTNILALNAAVEAARAGDQGRGFAVVAGEVRALAQRSANAAKEIKNLIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHC
VSVEKVESGSRLVDDAGKTMDDIVAQVKRVSDLIAEISSATEEQSSGVTQVDQAVSELDH
CCHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ITQQNAALVEQSTAASESLKQQATRLVNAVSVFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]