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The map label for this gene is lldD [H]

Identifier: 91783388

GI number: 91783388

Start: 2234389

End: 2235579

Strand: Direct

Name: lldD [H]

Synonym: Bxe_A2428

Alternate gene names: 91783388

Gene position: 2234389-2235579 (Clockwise)

Preceding gene: 91783387

Following gene: 91783389

Centisome position: 45.64

GC content: 66.58

Gene sequence:

>1191_bases
ATGCATGCGCGGCGCGCGGAGCAAACGGATCTACCCGCCCGCTTGCGCAACGTGCTGTGCCTGAACGATTTCGCGAACGT
GGCGAAGCGCCGTTTGCCCGGAGCGATGTACGCGTACGTGCACGGCTGGTCCGAGGATGGCGCGACACACCGGCGCAATC
TGTACGGCTTTGAGACACGCGCTTTCGTGCCGCGTGTGCTGGTCGATATCGAGCGGCGCGATACGCGCACGACGCTGTTC
GGCGTCGAATACGCAGCGCCGTTCGGCATTGCGCCGATGGGGTGCAGCCGTCTTGCCGCGGCGCACGCGGACGAACTGTT
GGCGCGTGAAGCGGCGACGGCGGGGCTGCCGTTCATCCTCAGCGGCGCTTCGCTGACGCCGCTCGAAACGGTGCGCGCGG
CGGGCTCGACAAGTTGGTTTCAGGCCTACATTCCCGGTGATTTCGCGCGCATCGATCCGATGCTGGAACGTGTTGCGTTA
GCGGGCTACGACACGCTGGTCGTCAATGTCGATACCGCCGTCCACCCGCAGCACGAATACGCCGACAAGCGCGGCTTCCG
CTCGCCGTTCAGACCGAGCGCGCAGCTTGCGTGGCAGGCGTTGACGCGGCTTCCGTGGTGCTGGCGCGTGCTCGGCGAGA
GCGTGCTGACGCGCCATCCGCTGCGCTTCGAGAATATGGATGCGATCGGCGGGCCACCGGTGTTTTCGCGCACGCTGGTG
CGCGATATCGGACGGCGCGGCGCGTTGTCGTGGGCGCATATCGAACGGATCCGGCAGCGCTGGCCGGGGCGTCTGGTGCT
AAAAGGCGTGATGTCCGCCGACGATGCGCTGCTCGCCCAGCGAGCGGGCATCGACGGCATCATCGTGTCGAATCATGGCG
GACGTCAGGTGGATTGCGCGCTCGGCGCGCTCGATGCGCTCGATGCGATTGCCGCGCGGGTGGATCGCGATCGTCTCGCG
CTGATCTATGACGGCGGCATCCGGCGCGGTTCCGACGTGCTGAAAGCGTTGCATGGCGGCGCGCATTTCGTGCTGGTTGG
ACGGCCTTTGTTGATGGCCGCAGCCGCCGCCGACGCGATAGGCATCGCGTACGCGCTCTCGCTCCTGCAGCGCGAAATCG
GCACGAATATGGGACTGCTCGGCATCAACCGCATCGACGAGGTGGCGCAGCTCGAACTGCGGCGCGACTGA

Upstream 100 bases:

>100_bases
TGTCGATCAGCGAGATGTTCGCGCTGCCGCAGGCGCAAACCACGACGCATCCGACGGCGCTGGGCCAGGCGCAAGCAGCG
GAACCGCAGCGTTAGCGCGG

Downstream 100 bases:

>100_bases
TTTCGGCCTTTGCGCGTTTTTCATAAACGTTATCAGGGAGAGGAACATGATGGACAAGCCAATCCGCGTACTCACGCCGA
CCTGCACGCTCGGCTACGGT

Product: putative L-lactate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MHARRAEQTDLPARLRNVLCLNDFANVAKRRLPGAMYAYVHGWSEDGATHRRNLYGFETRAFVPRVLVDIERRDTRTTLF
GVEYAAPFGIAPMGCSRLAAAHADELLAREAATAGLPFILSGASLTPLETVRAAGSTSWFQAYIPGDFARIDPMLERVAL
AGYDTLVVNVDTAVHPQHEYADKRGFRSPFRPSAQLAWQALTRLPWCWRVLGESVLTRHPLRFENMDAIGGPPVFSRTLV
RDIGRRGALSWAHIERIRQRWPGRLVLKGVMSADDALLAQRAGIDGIIVSNHGGRQVDCALGALDALDAIAARVDRDRLA
LIYDGGIRRGSDVLKALHGGAHFVLVGRPLLMAAAAADAIGIAYALSLLQREIGTNMGLLGINRIDEVAQLELRRD

Sequences:

>Translated_396_residues
MHARRAEQTDLPARLRNVLCLNDFANVAKRRLPGAMYAYVHGWSEDGATHRRNLYGFETRAFVPRVLVDIERRDTRTTLF
GVEYAAPFGIAPMGCSRLAAAHADELLAREAATAGLPFILSGASLTPLETVRAAGSTSWFQAYIPGDFARIDPMLERVAL
AGYDTLVVNVDTAVHPQHEYADKRGFRSPFRPSAQLAWQALTRLPWCWRVLGESVLTRHPLRFENMDAIGGPPVFSRTLV
RDIGRRGALSWAHIERIRQRWPGRLVLKGVMSADDALLAQRAGIDGIIVSNHGGRQVDCALGALDALDAIAARVDRDRLA
LIYDGGIRRGSDVLKALHGGAHFVLVGRPLLMAAAAADAIGIAYALSLLQREIGTNMGLLGINRIDEVAQLELRRD
>Mature_396_residues
MHARRAEQTDLPARLRNVLCLNDFANVAKRRLPGAMYAYVHGWSEDGATHRRNLYGFETRAFVPRVLVDIERRDTRTTLF
GVEYAAPFGIAPMGCSRLAAAHADELLAREAATAGLPFILSGASLTPLETVRAAGSTSWFQAYIPGDFARIDPMLERVAL
AGYDTLVVNVDTAVHPQHEYADKRGFRSPFRPSAQLAWQALTRLPWCWRVLGESVLTRHPLRFENMDAIGGPPVFSRTLV
RDIGRRGALSWAHIERIRQRWPGRLVLKGVMSADDALLAQRAGIDGIIVSNHGGRQVDCALGALDALDAIAARVDRDRLA
LIYDGGIRRGSDVLKALHGGAHFVLVGRPLLMAAAAADAIGIAYALSLLQREIGTNMGLLGINRIDEVAQLELRRD

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI54234014, Length=374, Percent_Identity=31.283422459893, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI7705393, Length=374, Percent_Identity=31.283422459893, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI11068137, Length=386, Percent_Identity=27.2020725388601, Blast_Score=143, Evalue=2e-34,
Organism=Escherichia coli, GI1790033, Length=375, Percent_Identity=35.2, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI193208036, Length=385, Percent_Identity=31.1688311688312, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32566217, Length=321, Percent_Identity=28.3489096573209, Blast_Score=114, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6323587, Length=408, Percent_Identity=28.921568627451, Blast_Score=159, Evalue=9e-40,
Organism=Drosophila melanogaster, GI78707188, Length=376, Percent_Identity=30.3191489361702, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281363140, Length=376, Percent_Identity=30.3191489361702, Blast_Score=141, Evalue=6e-34,
Organism=Drosophila melanogaster, GI78707190, Length=376, Percent_Identity=30.3191489361702, Blast_Score=141, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 43462; Mature: 43462

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHARRAEQTDLPARLRNVLCLNDFANVAKRRLPGAMYAYVHGWSEDGATHRRNLYGFETR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCCCHHH
AFVPRVLVDIERRDTRTTLFGVEYAAPFGIAPMGCSRLAAAHADELLAREAATAGLPFIL
HHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
SGASLTPLETVRAAGSTSWFQAYIPGDFARIDPMLERVALAGYDTLVVNVDTAVHPQHEY
CCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHH
ADKRGFRSPFRPSAQLAWQALTRLPWCWRVLGESVLTRHPLRFENMDAIGGPPVFSRTLV
HHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
RDIGRRGALSWAHIERIRQRWPGRLVLKGVMSADDALLAQRAGIDGIIVSNHGGRQVDCA
HHHHHCCCCHHHHHHHHHHHCCCCEEHHHHHCCHHHHHHHHCCCCEEEEECCCCCEEHHH
LGALDALDAIAARVDRDRLALIYDGGIRRGSDVLKALHGGAHFVLVGRPLLMAAAAADAI
HHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHH
GIAYALSLLQREIGTNMGLLGINRIDEVAQLELRRD
HHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCC
>Mature Secondary Structure
MHARRAEQTDLPARLRNVLCLNDFANVAKRRLPGAMYAYVHGWSEDGATHRRNLYGFETR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCCCCHHH
AFVPRVLVDIERRDTRTTLFGVEYAAPFGIAPMGCSRLAAAHADELLAREAATAGLPFIL
HHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
SGASLTPLETVRAAGSTSWFQAYIPGDFARIDPMLERVALAGYDTLVVNVDTAVHPQHEY
CCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHH
ADKRGFRSPFRPSAQLAWQALTRLPWCWRVLGESVLTRHPLRFENMDAIGGPPVFSRTLV
HHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
RDIGRRGALSWAHIERIRQRWPGRLVLKGVMSADDALLAQRAGIDGIIVSNHGGRQVDCA
HHHHHCCCCHHHHHHHHHHHCCCCEEHHHHHCCHHHHHHHHCCCCEEEEECCCCCEEHHH
LGALDALDAIAARVDRDRLALIYDGGIRRGSDVLKALHGGAHFVLVGRPLLMAAAAADAI
HHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHH
GIAYALSLLQREIGTNMGLLGINRIDEVAQLELRRD
HHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA