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The map label for this gene is mdtA [H]

Identifier: 91783242

GI number: 91783242

Start: 2080354

End: 2081583

Strand: Direct

Name: mdtA [H]

Synonym: Bxe_A2584

Alternate gene names: 91783242

Gene position: 2080354-2081583 (Clockwise)

Preceding gene: 91783241

Following gene: 91783245

Centisome position: 42.49

GC content: 58.78

Gene sequence:

>1230_bases
ATGAACGAACAAACTTCCATTTCGCGCGTCATTCCCGCGCAGCCAAGGACCGGACTTGGTGCCTTCGAGCCCCGGGTGCC
GGAACGAGCGGGTGCAATAATTGGCGGCGCGATTGTTCTTGCCCTGGTAGCACTGGGCATCGTACACGTATTCGTCTCCG
GCCTGATGACGAGTACACCGGGCTATGTAAAGCCACAGGACGACGGCAGCACGCAGTACGTCAATGTGGTGTTGCCAAAA
AAGGTATCGGGCAGCGGTGAAATCTTCTTGCCTGGCACGCTACACGGATACATCGAATCCCCGATCTATTCCCGGGCAAC
AGGTTACGTGTTGCACTGGTACGCTGATATTGGCACGCGAGTGACAAGGGGGCAGGTGCTTGCGATTCTGGACACACCGG
AGATCGACCAGGAACTGGCACAGGCCATCGCGCAACGGAACGAGGCGAACGCGACTCTGGCACTTGCCAGGACTTCATAC
GAGCGCTGGCAGGAACTTCGCGAACACGATGTAGCGTCCGAGCAGGCACTGGAAGAGCGCCAGAGCACATATATGCAGGA
CGTTGCCAGTCTCGAGGCAGCCGACGCCAACGTGCAGCGTCTGCGGCAACTGGAGGCGTTCAAGCGCATCGTAGCGCCGT
TCTCCGGCGTCATCACCCAGCGCAATGTCGACATAGGCGACCTGGTCTATGCAGGCAATGTGTCGGGCCGCGCGCTCTTT
GCGATGGTGCAGGCGGACCCGCTGAGGGTGTATGTGCAGCTACCGCAGGCTTACGCACAGAATGTGAAGCAGGGGCAGGA
CGTGACGGTTACACAGGCTGAATTGCCTGGGCAACGGTTCCACGGCTCGATTGCTCATATCTCCGGCGCAATCGATGCCT
CGACCCGTTCGCTGCAGCTGGAAGTGAGATTACCCAACCCCGATAACAGGCTGAGACCAGGTGCGTATGTACAGGTGGCG
CTACGGCTCTCTGCTGACGGGCCGCTTCTCGTTCCGGACAATGTGCTGGTGTTTCGTTCGGAAGGGCCTCGCGTGGCGGT
CGTCGGTCAGGATGGCAAAGTTCAGTTACGGAAAATCGTCATTCGTCGCGACCTGGGCGAGTCGCTTGAGATCGAAAGCG
GTATCGGTCCAGCGGACAAGATCATTATCAACCCCAGCGATTCCATCGCCGATGGAGAGCACGTGCGCATCGTTCCTGGC
CAACAGATGGTGAGATTACCAACGTCGTAA

Upstream 100 bases:

>100_bases
CAGTGCCCGATAGCCTGGCTTCCAGTGGCCGCGGTTCCCGGGAAAGGCGTGTCCCGACCGATTCGTGACGGCCACCATGA
TTGCCACCCAGGTGAATGAC

Downstream 100 bases:

>100_bases
AGCAGGGGCTCAAATGAAGTCGACCTATACGAGGCCAAAAACCGCATGCCTGGAAGGCAGGACGAATTCGAACCGCGGAC
CAGTTCGAGCAGCGCCTGCA

Product: CzcB subfamily membrane fusion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MNEQTSISRVIPAQPRTGLGAFEPRVPERAGAIIGGAIVLALVALGIVHVFVSGLMTSTPGYVKPQDDGSTQYVNVVLPK
KVSGSGEIFLPGTLHGYIESPIYSRATGYVLHWYADIGTRVTRGQVLAILDTPEIDQELAQAIAQRNEANATLALARTSY
ERWQELREHDVASEQALEERQSTYMQDVASLEAADANVQRLRQLEAFKRIVAPFSGVITQRNVDIGDLVYAGNVSGRALF
AMVQADPLRVYVQLPQAYAQNVKQGQDVTVTQAELPGQRFHGSIAHISGAIDASTRSLQLEVRLPNPDNRLRPGAYVQVA
LRLSADGPLLVPDNVLVFRSEGPRVAVVGQDGKVQLRKIVIRRDLGESLEIESGIGPADKIIINPSDSIADGEHVRIVPG
QQMVRLPTS

Sequences:

>Translated_409_residues
MNEQTSISRVIPAQPRTGLGAFEPRVPERAGAIIGGAIVLALVALGIVHVFVSGLMTSTPGYVKPQDDGSTQYVNVVLPK
KVSGSGEIFLPGTLHGYIESPIYSRATGYVLHWYADIGTRVTRGQVLAILDTPEIDQELAQAIAQRNEANATLALARTSY
ERWQELREHDVASEQALEERQSTYMQDVASLEAADANVQRLRQLEAFKRIVAPFSGVITQRNVDIGDLVYAGNVSGRALF
AMVQADPLRVYVQLPQAYAQNVKQGQDVTVTQAELPGQRFHGSIAHISGAIDASTRSLQLEVRLPNPDNRLRPGAYVQVA
LRLSADGPLLVPDNVLVFRSEGPRVAVVGQDGKVQLRKIVIRRDLGESLEIESGIGPADKIIINPSDSIADGEHVRIVPG
QQMVRLPTS
>Mature_409_residues
MNEQTSISRVIPAQPRTGLGAFEPRVPERAGAIIGGAIVLALVALGIVHVFVSGLMTSTPGYVKPQDDGSTQYVNVVLPK
KVSGSGEIFLPGTLHGYIESPIYSRATGYVLHWYADIGTRVTRGQVLAILDTPEIDQELAQAIAQRNEANATLALARTSY
ERWQELREHDVASEQALEERQSTYMQDVASLEAADANVQRLRQLEAFKRIVAPFSGVITQRNVDIGDLVYAGNVSGRALF
AMVQADPLRVYVQLPQAYAQNVKQGQDVTVTQAELPGQRFHGSIAHISGAIDASTRSLQLEVRLPNPDNRLRPGAYVQVA
LRLSADGPLLVPDNVLVFRSEGPRVAVVGQDGKVQLRKIVIRRDLGESLEIESGIGPADKIIINPSDSIADGEHVRIVPG
QQMVRLPTS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=335, Percent_Identity=24.4776119402985, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1789929, Length=329, Percent_Identity=25.531914893617, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786668, Length=321, Percent_Identity=25.8566978193146, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081796, Length=316, Percent_Identity=25, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789665, Length=328, Percent_Identity=26.219512195122, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786787, Length=192, Percent_Identity=25.5208333333333, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44368; Mature: 44368

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEQTSISRVIPAQPRTGLGAFEPRVPERAGAIIGGAIVLALVALGIVHVFVSGLMTSTP
CCCCCCCHHCCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GYVKPQDDGSTQYVNVVLPKKVSGSGEIFLPGTLHGYIESPIYSRATGYVLHWYADIGTR
CCCCCCCCCCCEEEEEEECCCCCCCCCEEECCCCHHHHCCCHHHCCCCEEEEEEECCCCE
VTRGQVLAILDTPEIDQELAQAIAQRNEANATLALARTSYERWQELREHDVASEQALEER
EECCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCHHHHHHHHH
QSTYMQDVASLEAADANVQRLRQLEAFKRIVAPFSGVITQRNVDIGDLVYAGNVSGRALF
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCCCEEE
AMVQADPLRVYVQLPQAYAQNVKQGQDVTVTQAELPGQRFHGSIAHISGAIDASTRSLQL
EEEECCCEEEEEECCHHHHHHHCCCCCEEEEEHHCCCHHHCCCHHHCCCCCCCCCEEEEE
EVRLPNPDNRLRPGAYVQVALRLSADGPLLVPDNVLVFRSEGPRVAVVGQDGKVQLRKIV
EEECCCCCCCCCCCCEEEEEEEECCCCCEECCCCEEEEECCCCEEEEECCCCCEEHHHHH
IRRDLGESLEIESGIGPADKIIINPSDSIADGEHVRIVPGQQMVRLPTS
HHHCCCCCEEECCCCCCCCEEEECCCCCCCCCCEEEEECCCCEEECCCC
>Mature Secondary Structure
MNEQTSISRVIPAQPRTGLGAFEPRVPERAGAIIGGAIVLALVALGIVHVFVSGLMTSTP
CCCCCCCHHCCCCCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GYVKPQDDGSTQYVNVVLPKKVSGSGEIFLPGTLHGYIESPIYSRATGYVLHWYADIGTR
CCCCCCCCCCCEEEEEEECCCCCCCCCEEECCCCHHHHCCCHHHCCCCEEEEEEECCCCE
VTRGQVLAILDTPEIDQELAQAIAQRNEANATLALARTSYERWQELREHDVASEQALEER
EECCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCHHHHHHHHH
QSTYMQDVASLEAADANVQRLRQLEAFKRIVAPFSGVITQRNVDIGDLVYAGNVSGRALF
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCCCEEE
AMVQADPLRVYVQLPQAYAQNVKQGQDVTVTQAELPGQRFHGSIAHISGAIDASTRSLQL
EEEECCCEEEEEECCHHHHHHHCCCCCEEEEEHHCCCHHHCCCHHHCCCCCCCCCEEEEE
EVRLPNPDNRLRPGAYVQVALRLSADGPLLVPDNVLVFRSEGPRVAVVGQDGKVQLRKIV
EEECCCCCCCCCCCCEEEEEEEECCCCCEECCCCEEEEECCCCEEEEECCCCCEEHHHHH
IRRDLGESLEIESGIGPADKIIINPSDSIADGEHVRIVPGQQMVRLPTS
HHHCCCCCEEECCCCCCCCEEEECCCCCCCCCCEEEEECCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]