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The map label for this gene is hutC [H]

Identifier: 91782877

GI number: 91782877

Start: 1666475

End: 1667170

Strand: Direct

Name: hutC [H]

Synonym: Bxe_A2946

Alternate gene names: 91782877

Gene position: 1666475-1667170 (Clockwise)

Preceding gene: 91782876

Following gene: 91782878

Centisome position: 34.04

GC content: 64.51

Gene sequence:

>696_bases
ATGAACGCACCGGCCTATCAGGGCATCAAGGACTTCATCCTCGCGCGCATCCATGCGGGCGAATGGGGTGAAGGCGACCA
GGTGCCCTCCGAAAACGAGCTCGCGCGCGAATTCAACGTGGCGCGCATGACGGTCAACCGCGCGTTGCGCGAGCTGACCT
CGGAGCAGGTGCTCACGCGTGTGCAAGGTTCGGGCACGTTCGTGGCCCGTCCCAAGTACGAATCGACGCTGGTGGCGATC
CGCAGCATCTCCGACGAAATCGTCGCGCGCGGTCATCGTTATCAGGCGAAGGTGCTGCATATCGGCGCGAGCATCGCCGA
CGAAGCGCTCGCCGGGGAAATGCAGGTGAGCGCGGGCAGCCCGGTGTTTCATTCGCGCGTGCTGCATTTCGAAAACGACG
AGCCGGTGCAGCTCGAAGAGCGTTGGGTCAATCCGGCGGTCGCGCCCGAGTACGCGCGGCAGGACTTCACCAACACCACG
CCGAACCAGTATCTCGTGCGCGTCGCGCCGTTGCAGCGGGTCGAGTACCGCATCGAGGCGCTGGCCGCCGACGCCGATAC
GCGCGAACTGTTGACGATGGACGAACTGGAGCCCTGCCTCGTGCTGCATCGGCGCACGTGGTCGCAAAGCCAGGTCGCAT
CGATCGCCAATCTCTGGCATCCCGGCAGCCGCTATCGCTTCACCGGACATTTCTGA

Upstream 100 bases:

>100_bases
CGCGGCTGTCACGCGCCTCGTGCAGAACGGCACGATCGCGAAGCTGAGCCCGTTCTCCTTCGCGTCCGAACAGTAAGTTT
CAAGCACGCATATCAAGCCA

Downstream 100 bases:

>100_bases
CTACGCCGTCTTTTCCGAACCCGAATCTTTTTCGACCATCTTCAAGCATTCCGAGGGCCATCATGAACAACCCGAAACAC
ATCGACCCGCGTCTCGATCC

Product: histidine utilization repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNAPAYQGIKDFILARIHAGEWGEGDQVPSENELAREFNVARMTVNRALRELTSEQVLTRVQGSGTFVARPKYESTLVAI
RSISDEIVARGHRYQAKVLHIGASIADEALAGEMQVSAGSPVFHSRVLHFENDEPVQLEERWVNPAVAPEYARQDFTNTT
PNQYLVRVAPLQRVEYRIEALAADADTRELLTMDELEPCLVLHRRTWSQSQVASIANLWHPGSRYRFTGHF

Sequences:

>Translated_231_residues
MNAPAYQGIKDFILARIHAGEWGEGDQVPSENELAREFNVARMTVNRALRELTSEQVLTRVQGSGTFVARPKYESTLVAI
RSISDEIVARGHRYQAKVLHIGASIADEALAGEMQVSAGSPVFHSRVLHFENDEPVQLEERWVNPAVAPEYARQDFTNTT
PNQYLVRVAPLQRVEYRIEALAADADTRELLTMDELEPCLVLHRRTWSQSQVASIANLWHPGSRYRFTGHF
>Mature_231_residues
MNAPAYQGIKDFILARIHAGEWGEGDQVPSENELAREFNVARMTVNRALRELTSEQVLTRVQGSGTFVARPKYESTLVAI
RSISDEIVARGHRYQAKVLHIGASIADEALAGEMQVSAGSPVFHSRVLHFENDEPVQLEERWVNPAVAPEYARQDFTNTT
PNQYLVRVAPLQRVEYRIEALAADADTRELLTMDELEPCLVLHRRTWSQSQVASIANLWHPGSRYRFTGHF

Specific function: Repressor which binds to the hutP region in the histidine utilization (hut) operon. It blocks the expression of all the hut genes in the absence of inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=201, Percent_Identity=29.3532338308458, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI87082252, Length=147, Percent_Identity=29.9319727891156, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1788418, Length=214, Percent_Identity=27.1028037383178, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790118, Length=138, Percent_Identity=23.9130434782609, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010248
- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 26082; Mature: 26082

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPAYQGIKDFILARIHAGEWGEGDQVPSENELAREFNVARMTVNRALRELTSEQVLTR
CCCCHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQGSGTFVARPKYESTLVAIRSISDEIVARGHRYQAKVLHIGASIADEALAGEMQVSAGS
HCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHCCEEECCCC
PVFHSRVLHFENDEPVQLEERWVNPAVAPEYARQDFTNTTPNQYLVRVAPLQRVEYRIEA
CHHHHEEEECCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHH
LAADADTRELLTMDELEPCLVLHRRTWSQSQVASIANLWHPGSRYRFTGHF
HHCCCCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCC
>Mature Secondary Structure
MNAPAYQGIKDFILARIHAGEWGEGDQVPSENELAREFNVARMTVNRALRELTSEQVLTR
CCCCHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQGSGTFVARPKYESTLVAIRSISDEIVARGHRYQAKVLHIGASIADEALAGEMQVSAGS
HCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHCCEEECCCC
PVFHSRVLHFENDEPVQLEERWVNPAVAPEYARQDFTNTTPNQYLVRVAPLQRVEYRIEA
CHHHHEEEECCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHH
LAADADTRELLTMDELEPCLVLHRRTWSQSQVASIANLWHPGSRYRFTGHF
HHCCCCHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]