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The map label for this gene is sppA [H]

Identifier: 91782762

GI number: 91782762

Start: 1529294

End: 1530175

Strand: Direct

Name: sppA [H]

Synonym: Bxe_A3063

Alternate gene names: 91782762

Gene position: 1529294-1530175 (Clockwise)

Preceding gene: 91782761

Following gene: 91782763

Centisome position: 31.24

GC content: 62.36

Gene sequence:

>882_bases
ATGAGCAACTATCCCCATCTTGCAACGCGGCTCTTCAACGTGCCGATCGCAATCGCGCCGCAGAAGGCCGAAATCGTAAT
GGCAGCGCTCGCGGATCGTTTCGGAATCGCGAAGATGTTCCGCGGCGGCGGCGACGTGGTGGTGCTGGCTGACGGTGGCG
CGCAGGCATTCCTGCAAAGCGCCAATACGTCGCAGGCCGACTATCGCCCGTATGAGGTCGTGGAGGGGGTTGCGATCGTT
CCTATCGAGGGAACGCTTGTGCACAAGCTCGGCGAATTGCGGCCGTACTCGGGGATGACGGGTTACGACGGCATCCGCGC
CAATCTGAGCATGGCGATGGCCGACGAGAGCGTTCGAGCGATTGTGCTCGATATCGATTCGCCGGGCGGCGAGGTCGCCG
GCTGCTTCGATCTCGTGGACTCGATCTATGCCGCGCGCGACGTCAAGCCGATCTGGGCCATTTGCACCGAGAGTGCCTAT
TCGGCCGCGTACGCGATCGCGACGGCGGCGAGCCGGATCATCGTCCCGCGCACCGGTGGCACCGGCAGCGTCGGCGTCAT
TTGTATGCATGTCGATTTTTCGCAGGCACTGACGAAAGCGGGAATCGAGGTCGAGCTCATCTATTTCGGCGACAAGAAAG
CCGACGGCAGCGACATGAAGCCGCTGTCGAAAGACGCCCGCGCACGGTTTCAATCCGATGTCGACGCGATGGGCCAGTTA
TTTGTTGAGACCGTGGCGCGTAACCGCGGCCTCACTACCGCAAATGTGCGAGGCACACAGGCCGGCACATTCCTCGGCGC
CGCTGGCGTCGAAATCGGCTTCGCGGACGCAGTGATGTCGCCCGATGAAGCATTCGCATCCTTGCTCGACGAGCTGGGCT
GA

Upstream 100 bases:

>100_bases
AAATCGAGGCCTTCCGCGAACGTGGCATCCCGCTACCCGAATGGGGCGGCAGCGAGATGGCCACGCGCACCGACGAACCT
CCCCAGGAGCCGCAGGCAGC

Downstream 100 bases:

>100_bases
CTTATCCCACCAACAGGGTAATCACATGAGCAATTTGTTTCGTAACCTGGCTGCGCGAGGTGGTATCAGCTTCGCCCACC
TCGGTAAAGGAGCGGCCCGC

Product: serine peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSNYPHLATRLFNVPIAIAPQKAEIVMAALADRFGIAKMFRGGGDVVVLADGGAQAFLQSANTSQADYRPYEVVEGVAIV
PIEGTLVHKLGELRPYSGMTGYDGIRANLSMAMADESVRAIVLDIDSPGGEVAGCFDLVDSIYAARDVKPIWAICTESAY
SAAYAIATAASRIIVPRTGGTGSVGVICMHVDFSQALTKAGIEVELIYFGDKKADGSDMKPLSKDARARFQSDVDAMGQL
FVETVARNRGLTTANVRGTQAGTFLGAAGVEIGFADAVMSPDEAFASLLDELG

Sequences:

>Translated_293_residues
MSNYPHLATRLFNVPIAIAPQKAEIVMAALADRFGIAKMFRGGGDVVVLADGGAQAFLQSANTSQADYRPYEVVEGVAIV
PIEGTLVHKLGELRPYSGMTGYDGIRANLSMAMADESVRAIVLDIDSPGGEVAGCFDLVDSIYAARDVKPIWAICTESAY
SAAYAIATAASRIIVPRTGGTGSVGVICMHVDFSQALTKAGIEVELIYFGDKKADGSDMKPLSKDARARFQSDVDAMGQL
FVETVARNRGLTTANVRGTQAGTFLGAAGVEIGFADAVMSPDEAFASLLDELG
>Mature_292_residues
SNYPHLATRLFNVPIAIAPQKAEIVMAALADRFGIAKMFRGGGDVVVLADGGAQAFLQSANTSQADYRPYEVVEGVAIVP
IEGTLVHKLGELRPYSGMTGYDGIRANLSMAMADESVRAIVLDIDSPGGEVAGCFDLVDSIYAARDVKPIWAICTESAYS
AAYAIATAASRIIVPRTGGTGSVGVICMHVDFSQALTKAGIEVELIYFGDKKADGSDMKPLSKDARARFQSDVDAMGQLF
VETVARNRGLTTANVRGTQAGTFLGAAGVEIGFADAVMSPDEAFASLLDELG

Specific function: Digestion of cleaved signal peptides. Required for efficient processing of precursors under conditions of hyper-secretion [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=172, Percent_Identity=26.7441860465116, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 30783; Mature: 30652

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYPHLATRLFNVPIAIAPQKAEIVMAALADRFGIAKMFRGGGDVVVLADGGAQAFLQS
CCCCCHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHC
ANTSQADYRPYEVVEGVAIVPIEGTLVHKLGELRPYSGMTGYDGIRANLSMAMADESVRA
CCCCCCCCCCHHHHCCEEEEECCCHHHHHHHCCCCCCCCCCCCCHHHCEEEEECCCCEEE
IVLDIDSPGGEVAGCFDLVDSIYAARDVKPIWAICTESAYSAAYAIATAASRIIVPRTGG
EEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCC
TGSVGVICMHVDFSQALTKAGIEVELIYFGDKKADGSDMKPLSKDARARFQSDVDAMGQL
CCCEEEEEEEECHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FVETVARNRGLTTANVRGTQAGTFLGAAGVEIGFADAVMSPDEAFASLLDELG
HHHHHHHCCCCEEEECCCCCCCCEEECCCCEEEHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SNYPHLATRLFNVPIAIAPQKAEIVMAALADRFGIAKMFRGGGDVVVLADGGAQAFLQS
CCCCHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHC
ANTSQADYRPYEVVEGVAIVPIEGTLVHKLGELRPYSGMTGYDGIRANLSMAMADESVRA
CCCCCCCCCCHHHHCCEEEEECCCHHHHHHHCCCCCCCCCCCCCHHHCEEEEECCCCEEE
IVLDIDSPGGEVAGCFDLVDSIYAARDVKPIWAICTESAYSAAYAIATAASRIIVPRTGG
EEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCC
TGSVGVICMHVDFSQALTKAGIEVELIYFGDKKADGSDMKPLSKDARARFQSDVDAMGQL
CCCEEEEEEEECHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FVETVARNRGLTTANVRGTQAGTFLGAAGVEIGFADAVMSPDEAFASLLDELG
HHHHHHHCCCCEEEECCCCCCCCEEECCCCEEEHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10455123 [H]