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The map label for this gene is hmrR [H]

Identifier: 91782664

GI number: 91782664

Start: 1444708

End: 1445175

Strand: Direct

Name: hmrR [H]

Synonym: Bxe_A3161

Alternate gene names: 91782664

Gene position: 1444708-1445175 (Clockwise)

Preceding gene: 91782661

Following gene: 91782665

Centisome position: 29.51

GC content: 61.11

Gene sequence:

>468_bases
ATGATGGCAAGGTGTACGATCGATTCACATACAAGGGGAAACGCCATGAATATCGGTGAAGCGGCCCGCGTGTCGGGCGT
CACGGCGAAAATGATTCGCTACTATGAAAGCGTCGGCTTGCTGGCGGCCAAAGCGCGCACGAGCGCCGGCTATCGCGTAT
ATGGCCCGCAAGAGGTTCATTCGTTGCGCTTCATCCGCCAGGCGCGCCGGCTCGGCTTTCTGGTCGAAGACATCCGGCGG
CTGCTCGCGCTGTGGCACGATCGCTCGCGCGCCAGTGCCGAGGTGAAGGCGATTGCGCTGGAACACGTTGCAGAGCTGGA
TCGGCGCATCGCCGAACTGACTGATATGCGCGACACGTTGGCGCACCTGGCCGACCATTGCCACGGCGACGACCGCCCTG
ATTGCCCGATTATCGAGCGGCTTGCCGATACTGACCTGGTTTCAGGACAGGGTTGTCATCCGATTTGA

Upstream 100 bases:

>100_bases
TCAACCTGGAATTCGATCGTCATCGGGATTACCTCGGAAAAATGGATATTGCGATAGTTGAATTATGCCTGCCGATCCGC
AATTCAGTGGTGACCTTCCC

Downstream 100 bases:

>100_bases
CGTGTTGTGGCGTCGGTTCGCCAGCCGAAGCCTGAATTCGCGGCAATTCGAGTAGCATTTGCACCAAAACAATGCGTAAA
AATATGGGGCAACATCATCC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: Copper efflux regulator; Copper export regulator [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MMARCTIDSHTRGNAMNIGEAARVSGVTAKMIRYYESVGLLAAKARTSAGYRVYGPQEVHSLRFIRQARRLGFLVEDIRR
LLALWHDRSRASAEVKAIALEHVAELDRRIAELTDMRDTLAHLADHCHGDDRPDCPIIERLADTDLVSGQGCHPI

Sequences:

>Translated_155_residues
MMARCTIDSHTRGNAMNIGEAARVSGVTAKMIRYYESVGLLAAKARTSAGYRVYGPQEVHSLRFIRQARRLGFLVEDIRR
LLALWHDRSRASAEVKAIALEHVAELDRRIAELTDMRDTLAHLADHCHGDDRPDCPIIERLADTDLVSGQGCHPI
>Mature_155_residues
MMARCTIDSHTRGNAMNIGEAARVSGVTAKMIRYYESVGLLAAKARTSAGYRVYGPQEVHSLRFIRQARRLGFLVEDIRR
LLALWHDRSRASAEVKAIALEHVAELDRRIAELTDMRDTLAHLADHCHGDDRPDCPIIERLADTDLVSGQGCHPI

Specific function: Regulates the transcription of actP. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations. In the absence of copper, it negatively regulates the transcription of actP [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=48.0314960629921, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1789687, Length=138, Percent_Identity=38.4057971014493, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 17331; Mature: 17331

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMARCTIDSHTRGNAMNIGEAARVSGVTAKMIRYYESVGLLAAKARTSAGYRVYGPQEVH
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHH
SLRFIRQARRLGFLVEDIRRLLALWHDRSRASAEVKAIALEHVAELDRRIAELTDMRDTL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHLADHCHGDDRPDCPIIERLADTDLVSGQGCHPI
HHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MMARCTIDSHTRGNAMNIGEAARVSGVTAKMIRYYESVGLLAAKARTSAGYRVYGPQEVH
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHH
SLRFIRQARRLGFLVEDIRRLLALWHDRSRASAEVKAIALEHVAELDRRIAELTDMRDTL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHLADHCHGDDRPDCPIIERLADTDLVSGQGCHPI
HHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11936079 [H]