Click here to switch to the map view.

The map label for this gene is tpiA [H]

Identifier: 91782610

GI number: 91782610

Start: 1380735

End: 1381511

Strand: Direct

Name: tpiA [H]

Synonym: Bxe_A3216

Alternate gene names: 91782610

Gene position: 1380735-1381511 (Clockwise)

Preceding gene: 91782609

Following gene: 91782611

Centisome position: 28.2

GC content: 64.74

Gene sequence:

>777_bases
ATGTCGAAACAACGAGCCAAACTGGTAGTCGGTAACTGGAAGATGCACGGGCGCCTCGCCGAAAATGCCGTGCTGTTGCA
GGCGGTGGCGCAAGGCGCGGGCGAATTGCCGGCTCAAGTGCGCGTCGGTGTTTGCGTGCCGAGCCCGTATCTCGCGCAGT
CTCAATCGTTGCTGGAAGGCAGCCGGGTGGCGTGGGGCGTGCAGGACGTGTCAGCGTTCACGCATGGCGCCTACACCGGC
GAAGTGGCCGCGCCGATGGCGGTGGATTTCGGTGCCACGCTGGCGATCGTCGGGCATTCGGAGCGCCGTGCCTATCATCG
CGAGAGCGCCGAGCTGGTCGCGGTGAAAACGCAGCGCGTGCTGGAAGCGGGTTTGACGCCGATCGTCTGTGTCGGCGAAA
CGCTTGAAGAGCGCGAAGCCGGTTCGACCGAGCAGGTGGTCGGCATGCAACTGGACGAAGTGCTGGCGAAATTGTCGGAG
CAGGAGGCGGCGCGGATTGTCGTCGCGTATGAGCCGGTTTGGGCTATCGGCACCGGCAAGAGCGCGAGCTCTGAACAGGC
GCAAGCGGTTCACGCGTTCCTGCGCGCGCGTCTGGCGGCAAAGGGCGCGGCAGTGGCGGATGTCCCGCTGTTGTACGGCG
GCAGCGTGAAACCGGAAAACGCGGAAGAATTGTTCCGCCAGCCGGATATCGACGGTGGCCTGATCGGCGGCGCGTCGTTG
AAAGCCCAGGATTTCCTGGTGATCTGCAAGGCGGCCACAACGAGCGTCGCCGGTTGA

Upstream 100 bases:

>100_bases
CACCCCACGCAGTAAAATTGCGCGTTTTGCGCACGCCGCATGAATCCGCAAGGCGGACTGTAAGCGCAAACGAAGTCCGC
CGCCAAGACAAGACGAGACG

Downstream 100 bases:

>100_bases
GCAGGGCGCCCTGGCGAGAATGACCCCATCCCGTGCAACACGTAGTGTGTTGCGCGGTTAAATAAAGACTCAGGTGAGTG
TGATGCTGTATTTGAAAACA

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSKQRAKLVVGNWKMHGRLAENAVLLQAVAQGAGELPAQVRVGVCVPSPYLAQSQSLLEGSRVAWGVQDVSAFTHGAYTG
EVAAPMAVDFGATLAIVGHSERRAYHRESAELVAVKTQRVLEAGLTPIVCVGETLEEREAGSTEQVVGMQLDEVLAKLSE
QEAARIVVAYEPVWAIGTGKSASSEQAQAVHAFLRARLAAKGAAVADVPLLYGGSVKPENAEELFRQPDIDGGLIGGASL
KAQDFLVICKAATTSVAG

Sequences:

>Translated_258_residues
MSKQRAKLVVGNWKMHGRLAENAVLLQAVAQGAGELPAQVRVGVCVPSPYLAQSQSLLEGSRVAWGVQDVSAFTHGAYTG
EVAAPMAVDFGATLAIVGHSERRAYHRESAELVAVKTQRVLEAGLTPIVCVGETLEEREAGSTEQVVGMQLDEVLAKLSE
QEAARIVVAYEPVWAIGTGKSASSEQAQAVHAFLRARLAAKGAAVADVPLLYGGSVKPENAEELFRQPDIDGGLIGGASL
KAQDFLVICKAATTSVAG
>Mature_257_residues
SKQRAKLVVGNWKMHGRLAENAVLLQAVAQGAGELPAQVRVGVCVPSPYLAQSQSLLEGSRVAWGVQDVSAFTHGAYTGE
VAAPMAVDFGATLAIVGHSERRAYHRESAELVAVKTQRVLEAGLTPIVCVGETLEEREAGSTEQVVGMQLDEVLAKLSEQ
EAARIVVAYEPVWAIGTGKSASSEQAQAVHAFLRARLAAKGAAVADVPLLYGGSVKPENAEELFRQPDIDGGLIGGASLK
AQDFLVICKAATTSVAG

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=253, Percent_Identity=42.2924901185771, Blast_Score=175, Evalue=4e-44,
Organism=Homo sapiens, GI226529917, Length=253, Percent_Identity=42.2924901185771, Blast_Score=175, Evalue=5e-44,
Organism=Escherichia coli, GI1790353, Length=251, Percent_Identity=49.003984063745, Blast_Score=217, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI17536593, Length=250, Percent_Identity=48, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6320255, Length=241, Percent_Identity=41.0788381742739, Blast_Score=173, Evalue=3e-44,
Organism=Drosophila melanogaster, GI28572008, Length=249, Percent_Identity=43.7751004016064, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28572006, Length=249, Percent_Identity=43.7751004016064, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28572004, Length=249, Percent_Identity=43.7751004016064, Blast_Score=179, Evalue=2e-45,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 27013; Mature: 26882

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQRAKLVVGNWKMHGRLAENAVLLQAVAQGAGELPAQVRVGVCVPSPYLAQSQSLLEG
CCCCCCEEEEECEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHCC
SRVAWGVQDVSAFTHGAYTGEVAAPMAVDFGATLAIVGHSERRAYHRESAELVAVKTQRV
CCEEECHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEECHHHHHHHHCCCEEEEHHHHHH
LEAGLTPIVCVGETLEEREAGSTEQVVGMQLDEVLAKLSEQEAARIVVAYEPVWAIGTGK
HHHCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCEEEEECCC
SASSEQAQAVHAFLRARLAAKGAAVADVPLLYGGSVKPENAEELFRQPDIDGGLIGGASL
CCCHHHHHHHHHHHHHHHHHCCCCEECCCEEECCCCCCCCHHHHHHCCCCCCCEECCCCC
KAQDFLVICKAATTSVAG
CCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
SKQRAKLVVGNWKMHGRLAENAVLLQAVAQGAGELPAQVRVGVCVPSPYLAQSQSLLEG
CCCCCEEEEECEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHCC
SRVAWGVQDVSAFTHGAYTGEVAAPMAVDFGATLAIVGHSERRAYHRESAELVAVKTQRV
CCEEECHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEECHHHHHHHHCCCEEEEHHHHHH
LEAGLTPIVCVGETLEEREAGSTEQVVGMQLDEVLAKLSEQEAARIVVAYEPVWAIGTGK
HHHCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCEEEEECCC
SASSEQAQAVHAFLRARLAAKGAAVADVPLLYGGSVKPENAEELFRQPDIDGGLIGGASL
CCCHHHHHHHHHHHHHHHHHCCCCEECCCEEECCCCCCCCHHHHHHCCCCCCCEECCCCC
KAQDFLVICKAATTSVAG
CCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA