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The map label for this gene is atoC [H]

Identifier: 91782455

GI number: 91782455

Start: 1201160

End: 1202560

Strand: Direct

Name: atoC [H]

Synonym: Bxe_A3376

Alternate gene names: 91782455

Gene position: 1201160-1202560 (Clockwise)

Preceding gene: 91782454

Following gene: 91782456

Centisome position: 24.53

GC content: 63.95

Gene sequence:

>1401_bases
ATGCCACATGTACTGATTGTCGATGACGATGCCGGTACCCGCGAGGCGCTTTCCGCCATCATCGGGGAAGACGGTCTGAC
CACCGCCACCGCGGGCGATTTGCGCGAAGCGCGCATTCAACTGGTCCGGCAGATGCCGGACGTCGTCTTTACGGACCTGA
AGCTGCCGGATGGCAGCGGGGTCGATCTGTTCGAAGATCTGGATCCGCGCTCCGGCGTGGAAGTGATCGTGATTACCGGC
CACGCCACGGTCGAGTCGGCGGTCAACGCGCTGAAAATGGGCGCCACCGACTATCTGGTCAAGCCGATCAACATGCAGCG
CGTGAAGGCGATTCTGTCGCGCCTGCCGCGCGCCGGCGACCTGAAAGCGGAAATCGGCACGCTGCGCGGCGAGTTGCGCC
GCATGGGCCGCTTCGGTCTGATGCTCGGCAATTCGCCGGCCATGCAGGAGGTCTACGACCAGATTGGCCGGGTCGCGCCA
ACGGCGGCCTCGGTCATGCTGGTGGGCGAATCGGGCACCGGCAAGGAAGTCGCCGCGCAGACGCTGCACCAGTTGAGCTT
GCGTCGCAAGCATGCGTTTCTCGCGGTGAACTGCGGCGCGATCTCGCCGAATCTGATCGAATCGGAAATGTTCGGCCACG
AGCGCGGCTCGTTCACCGGCGCGGACCGTCAGCATAAGGGCTATTTCGAGCGCGCGAACGGCGGCACGCTGTTCCTCGAC
GAAATCACCGAGATGCCGATCGAGTTGCAGGTCAAGCTGCTGCGTGTGCTCGAAACCGGCATGTTCATGCGGGTCGGCAC
GACCAAAGAGATCGAAACGGACGTGCGCCTGATTGCGGCCACCAACCGCGATCCCGAGCAGGCCGTGCTGGAAGGCAAGC
TGCGGCTGGACCTGTACCATCGGTTGAACGTGTTTCCGATCAGCCTGCCGCCGTTGCGTGATCGAGGCAAAGACGTGGAA
CTGCTGGCCCAGGCTTTCCTCGACGAACTCAACGAACGCCACAGCACCAGAAAGCATTTCCCGCCGGCCGTGAAGGACAT
GCTGATGTCGTATCCGTGGCCGGGCAATGTGCGCGAGCTGAAGAATTACGTGCAACGCGCACACATCATGTCGGGCTCGG
ATTCGGACAGCACGGCGACCGTGCCGCTGCAGATCACGCTGTCCAAGCCCGCGGCCGGTACGGCGATCACGATTCCGTTC
GGCACTTCGCTTGCCGAAGCGGACCGTCAGCTGATTCTGGCCACGCTCGAGCAGTGCGGCGGCGTGAAGACGCGGGCCGC
CGAGATTCTCGGCATCAGCCTCAAGACGCTGTATAACCGCCTCGTCGAGTACGGCAACGACGCACGGGAAGACGGCGACG
CCGCCGATGAATCGCGCGCGCTCGGCGGCGCGGACGCCTGA

Upstream 100 bases:

>100_bases
TGCCCGGTAACGCGGGCGAAACGCCGAGCCGCCGGCGCGCTCTTCAGCATGCGCCATAGCATGTTTTCCCATACCCACGC
TTGCAGGCTTTCGAGACGCG

Downstream 100 bases:

>100_bases
CGGCGCAACTCGTCGGTCGTGCGCCGGCGCCGCGCCATGCGGTGCCGCTTGACGCGTTGCTAGCGCCACGCCCCCGCCGG
GAGCGGCACTATAACGGCAC

Product: two component, sigma-54 specific, Fis family transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MPHVLIVDDDAGTREALSAIIGEDGLTTATAGDLREARIQLVRQMPDVVFTDLKLPDGSGVDLFEDLDPRSGVEVIVITG
HATVESAVNALKMGATDYLVKPINMQRVKAILSRLPRAGDLKAEIGTLRGELRRMGRFGLMLGNSPAMQEVYDQIGRVAP
TAASVMLVGESGTGKEVAAQTLHQLSLRRKHAFLAVNCGAISPNLIESEMFGHERGSFTGADRQHKGYFERANGGTLFLD
EITEMPIELQVKLLRVLETGMFMRVGTTKEIETDVRLIAATNRDPEQAVLEGKLRLDLYHRLNVFPISLPPLRDRGKDVE
LLAQAFLDELNERHSTRKHFPPAVKDMLMSYPWPGNVRELKNYVQRAHIMSGSDSDSTATVPLQITLSKPAAGTAITIPF
GTSLAEADRQLILATLEQCGGVKTRAAEILGISLKTLYNRLVEYGNDAREDGDAADESRALGGADA

Sequences:

>Translated_466_residues
MPHVLIVDDDAGTREALSAIIGEDGLTTATAGDLREARIQLVRQMPDVVFTDLKLPDGSGVDLFEDLDPRSGVEVIVITG
HATVESAVNALKMGATDYLVKPINMQRVKAILSRLPRAGDLKAEIGTLRGELRRMGRFGLMLGNSPAMQEVYDQIGRVAP
TAASVMLVGESGTGKEVAAQTLHQLSLRRKHAFLAVNCGAISPNLIESEMFGHERGSFTGADRQHKGYFERANGGTLFLD
EITEMPIELQVKLLRVLETGMFMRVGTTKEIETDVRLIAATNRDPEQAVLEGKLRLDLYHRLNVFPISLPPLRDRGKDVE
LLAQAFLDELNERHSTRKHFPPAVKDMLMSYPWPGNVRELKNYVQRAHIMSGSDSDSTATVPLQITLSKPAAGTAITIPF
GTSLAEADRQLILATLEQCGGVKTRAAEILGISLKTLYNRLVEYGNDAREDGDAADESRALGGADA
>Mature_465_residues
PHVLIVDDDAGTREALSAIIGEDGLTTATAGDLREARIQLVRQMPDVVFTDLKLPDGSGVDLFEDLDPRSGVEVIVITGH
ATVESAVNALKMGATDYLVKPINMQRVKAILSRLPRAGDLKAEIGTLRGELRRMGRFGLMLGNSPAMQEVYDQIGRVAPT
AASVMLVGESGTGKEVAAQTLHQLSLRRKHAFLAVNCGAISPNLIESEMFGHERGSFTGADRQHKGYFERANGGTLFLDE
ITEMPIELQVKLLRVLETGMFMRVGTTKEIETDVRLIAATNRDPEQAVLEGKLRLDLYHRLNVFPISLPPLRDRGKDVEL
LAQAFLDELNERHSTRKHFPPAVKDMLMSYPWPGNVRELKNYVQRAHIMSGSDSDSTATVPLQITLSKPAAGTAITIPFG
TSLAEADRQLILATLEQCGGVKTRAAEILGISLKTLYNRLVEYGNDAREDGDAADESRALGGADA

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=451, Percent_Identity=40.7982261640798, Blast_Score=335, Evalue=5e-93,
Organism=Escherichia coli, GI1790437, Length=446, Percent_Identity=41.0313901345291, Blast_Score=319, Evalue=3e-88,
Organism=Escherichia coli, GI1790299, Length=466, Percent_Identity=38.412017167382, Blast_Score=288, Evalue=7e-79,
Organism=Escherichia coli, GI1788905, Length=458, Percent_Identity=34.9344978165939, Blast_Score=244, Evalue=8e-66,
Organism=Escherichia coli, GI1789087, Length=317, Percent_Identity=43.5331230283912, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI87082117, Length=326, Percent_Identity=42.3312883435583, Blast_Score=238, Evalue=6e-64,
Organism=Escherichia coli, GI1789233, Length=318, Percent_Identity=42.1383647798742, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI87081872, Length=306, Percent_Identity=39.2156862745098, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1786524, Length=329, Percent_Identity=41.0334346504559, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87082152, Length=232, Percent_Identity=45.6896551724138, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1787583, Length=314, Percent_Identity=36.9426751592357, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1789828, Length=304, Percent_Identity=32.2368421052632, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI87081858, Length=312, Percent_Identity=28.8461538461538, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786911, Length=112, Percent_Identity=34.8214285714286, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=31.0924369747899, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787229, Length=123, Percent_Identity=34.9593495934959, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50773; Mature: 50642

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHVLIVDDDAGTREALSAIIGEDGLTTATAGDLREARIQLVRQMPDVVFTDLKLPDGSG
CCEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHEEEEEECCCCCC
VDLFEDLDPRSGVEVIVITGHATVESAVNALKMGATDYLVKPINMQRVKAILSRLPRAGD
CCHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHEECCCCHHHHHHHHHHCCCCCC
LKAEIGTLRGELRRMGRFGLMLGNSPAMQEVYDQIGRVAPTAASVMLVGESGTGKEVAAQ
CHHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHH
TLHQLSLRRKHAFLAVNCGAISPNLIESEMFGHERGSFTGADRQHKGYFERANGGTLFLD
HHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCEEEEH
EITEMPIELQVKLLRVLETGMFMRVGTTKEIETDVRLIAATNRDPEQAVLEGKLRLDLYH
HHHCCCHHHHHHHHHHHHCCCEEEECCCCHHCCCEEEEEECCCCHHHHHHHHHHEEEEEC
RLNVFPISLPPLRDRGKDVELLAQAFLDELNERHSTRKHFPPAVKDMLMSYPWPGNVREL
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHH
KNYVQRAHIMSGSDSDSTATVPLQITLSKPAAGTAITIPFGTSLAEADRQLILATLEQCG
HHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHC
GVKTRAAEILGISLKTLYNRLVEYGNDAREDGDAADESRALGGADA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure 
PHVLIVDDDAGTREALSAIIGEDGLTTATAGDLREARIQLVRQMPDVVFTDLKLPDGSG
CEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHEEEEEECCCCCC
VDLFEDLDPRSGVEVIVITGHATVESAVNALKMGATDYLVKPINMQRVKAILSRLPRAGD
CCHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHEECCCCHHHHHHHHHHCCCCCC
LKAEIGTLRGELRRMGRFGLMLGNSPAMQEVYDQIGRVAPTAASVMLVGESGTGKEVAAQ
CHHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHH
TLHQLSLRRKHAFLAVNCGAISPNLIESEMFGHERGSFTGADRQHKGYFERANGGTLFLD
HHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCEEEEH
EITEMPIELQVKLLRVLETGMFMRVGTTKEIETDVRLIAATNRDPEQAVLEGKLRLDLYH
HHHCCCHHHHHHHHHHHHCCCEEEECCCCHHCCCEEEEEECCCCHHHHHHHHHHEEEEEC
RLNVFPISLPPLRDRGKDVELLAQAFLDELNERHSTRKHFPPAVKDMLMSYPWPGNVREL
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHH
KNYVQRAHIMSGSDSDSTATVPLQITLSKPAAGTAITIPFGTSLAEADRQLILATLEQCG
HHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHC
GVKTRAAEILGISLKTLYNRLVEYGNDAREDGDAADESRALGGADA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]