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The map label for this gene is yxlA [H]

Identifier: 91782393

GI number: 91782393

Start: 1133733

End: 1135049

Strand: Reverse

Name: yxlA [H]

Synonym: Bxe_A3437

Alternate gene names: 91782393

Gene position: 1135049-1133733 (Counterclockwise)

Preceding gene: 91782402

Following gene: 91782391

Centisome position: 23.18

GC content: 68.41

Gene sequence:

>1317_bases
ATGGCACAAGATCCACTCGCCGGCGACGCCGGTTCCACTTACGCACCGCTCACGCCGGTGCCCGACGCGCGACGCGCGTT
CCGCACCGGCGACGCGTTCGCGCTCTGGTTCTCGCTCGGCATCGGCCTGCTGGTCGCGCAGGCGGGTGCGCTGCTGGTGC
CGGGACTGTCGCTGCCGCATGCGTTGCTGGCCATCGTTATCGGCAGCGTGATCGGCGTGGTGCTGCTCGCTCTCGCGGGC
GTGATCGGCACGGATACGGGGCTTGCGGCGATGTCGTCGTTGCGGCCGACGCTCGGCGTGCGCGGCGCATCGGTGCCCGC
CGTGCTGAACGCGGTGCAACTGGTCGGCTGGGGCTCGTTCGAGGTAATCGTGATGCGCGATTCCGCCGACGCCCTCGCCA
AACAGGCCTTCGGCCTCTCCATGCCGCTCATCTGGACGGTGATCTTCGGCCTGCTCGCGACGCTGCTGGCGATCAGCGGG
CCGCTCTCGTTCGTGCGGCGCTTTCTGCGCACGTGGGGCATCTGGCTGTTGCTCGCGGGCGCGGCGTGGCTGACATGGAA
CCTGCTCGCAAAACACGATCTCGCTGCGCTGATGCAGCGTCCGGGCACGGGCGAGATGTCGTTCGGCGGCGCCATCGATC
TGGTGGTCGCCATGCCGCTGTCGTGGCTGCCGCTGATCGCCGATTACACCCGCTTCGGCCGGCGTGCCGGTGAGACGTTC
CGCGGCACGCTGCTCGGCTACGGCATCGCCAACATCTGGTTTTACGCGCTCGGCGCGGTCTACGGCCTCGCGGCAGGCGG
CGGCGACGCGCTGCTGACGAGCGCGCTGGCGCAAGCCGGCGGCGGTCTCGCCCTGCTGCTGATCCTGATCGACGAAGTCG
ACAACGCGTTCGCCGACATTCACTCCGCCGCGGTATCGACGGGCACGTTCTGGACGCGCGGCAGCGTGCCCATCCTGTCG
GCGGCATTCGGCGCGCTGTGCACGCTGATCGCGCTGCTCGTGCCGATGGCGAAGTATCAGAACTTCCTGCTGCTGATCGG
CTCGGTGTTCGCGCCGCTGTTCGGCGTGGTGCTGGTGGATCACTTCATCGTGCGCAAGCGCCGTATCGAAGCCGCGGTTC
TCGCCGACGTACGCGGCCGTTACGGCTTCTCGGGCGGCTGGCATCTGAGCGCGTTTCTCGCGTGGGCCATCGGCATCGTC
GCCTATCAGGCGATCAATCAATGGCTGCCGAATCTCGGCGCGACGCTGCCCGCGCTGGTGATCGGCGCGGTGTGCTATCT
GGCGTTCGTGTCGGCACGCAAGACGGCGTATGCCTGA

Upstream 100 bases:

>100_bases
CCGGCAAAGTACGACGCAACGGGGCACGTAATCGAAGCCCCAGCCGCGGACATGACAGCAGATGCAACATCGCAGGCAAC
ACCAACAGGGACAAGACCAG

Downstream 100 bases:

>100_bases
TTGAACTAACTCCACGGTTAAACGGAAAGGCCTGCAATTGCAGGCCTTTCCGTTTGCGCGGTCACTTCAGCGGGTGGACG
CCCGATACTCGACGCCCGGC

Product: nucleobase/cation symporter, (NCS1) family

Products: Proton [Cytoplasm]; cytosine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MAQDPLAGDAGSTYAPLTPVPDARRAFRTGDAFALWFSLGIGLLVAQAGALLVPGLSLPHALLAIVIGSVIGVVLLALAG
VIGTDTGLAAMSSLRPTLGVRGASVPAVLNAVQLVGWGSFEVIVMRDSADALAKQAFGLSMPLIWTVIFGLLATLLAISG
PLSFVRRFLRTWGIWLLLAGAAWLTWNLLAKHDLAALMQRPGTGEMSFGGAIDLVVAMPLSWLPLIADYTRFGRRAGETF
RGTLLGYGIANIWFYALGAVYGLAAGGGDALLTSALAQAGGGLALLLILIDEVDNAFADIHSAAVSTGTFWTRGSVPILS
AAFGALCTLIALLVPMAKYQNFLLLIGSVFAPLFGVVLVDHFIVRKRRIEAAVLADVRGRYGFSGGWHLSAFLAWAIGIV
AYQAINQWLPNLGATLPALVIGAVCYLAFVSARKTAYA

Sequences:

>Translated_438_residues
MAQDPLAGDAGSTYAPLTPVPDARRAFRTGDAFALWFSLGIGLLVAQAGALLVPGLSLPHALLAIVIGSVIGVVLLALAG
VIGTDTGLAAMSSLRPTLGVRGASVPAVLNAVQLVGWGSFEVIVMRDSADALAKQAFGLSMPLIWTVIFGLLATLLAISG
PLSFVRRFLRTWGIWLLLAGAAWLTWNLLAKHDLAALMQRPGTGEMSFGGAIDLVVAMPLSWLPLIADYTRFGRRAGETF
RGTLLGYGIANIWFYALGAVYGLAAGGGDALLTSALAQAGGGLALLLILIDEVDNAFADIHSAAVSTGTFWTRGSVPILS
AAFGALCTLIALLVPMAKYQNFLLLIGSVFAPLFGVVLVDHFIVRKRRIEAAVLADVRGRYGFSGGWHLSAFLAWAIGIV
AYQAINQWLPNLGATLPALVIGAVCYLAFVSARKTAYA
>Mature_437_residues
AQDPLAGDAGSTYAPLTPVPDARRAFRTGDAFALWFSLGIGLLVAQAGALLVPGLSLPHALLAIVIGSVIGVVLLALAGV
IGTDTGLAAMSSLRPTLGVRGASVPAVLNAVQLVGWGSFEVIVMRDSADALAKQAFGLSMPLIWTVIFGLLATLLAISGP
LSFVRRFLRTWGIWLLLAGAAWLTWNLLAKHDLAALMQRPGTGEMSFGGAIDLVVAMPLSWLPLIADYTRFGRRAGETFR
GTLLGYGIANIWFYALGAVYGLAAGGGDALLTSALAQAGGGLALLLILIDEVDNAFADIHSAAVSTGTFWTRGSVPILSA
AFGALCTLIALLVPMAKYQNFLLLIGSVFAPLFGVVLVDHFIVRKRRIEAAVLADVRGRYGFSGGWHLSAFLAWAIGIVA
YQAINQWLPNLGATLPALVIGAVCYLAFVSARKTAYA

Specific function: Required For Cytosine Transport Into The Cell. [C]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 45830; Mature: 45698

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQDPLAGDAGSTYAPLTPVPDARRAFRTGDAFALWFSLGIGLLVAQAGALLVPGLSLPH
CCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHCCCCCCHHH
ALLAIVIGSVIGVVLLALAGVIGTDTGLAAMSSLRPTLGVRGASVPAVLNAVQLVGWGSF
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHCCCCE
EVIVMRDSADALAKQAFGLSMPLIWTVIFGLLATLLAISGPLSFVRRFLRTWGIWLLLAG
EEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AAWLTWNLLAKHDLAALMQRPGTGEMSFGGAIDLVVAMPLSWLPLIADYTRFGRRAGETF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RGTLLGYGIANIWFYALGAVYGLAAGGGDALLTSALAQAGGGLALLLILIDEVDNAFADI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
HSAAVSTGTFWTRGSVPILSAAFGALCTLIALLVPMAKYQNFLLLIGSVFAPLFGVVLVD
HHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HFIVRKRRIEAAVLADVRGRYGFSGGWHLSAFLAWAIGIVAYQAINQWLPNLGATLPALV
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IGAVCYLAFVSARKTAYA
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; cytosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + cytosine [Periplasm] = Proton [Cytoplasm] + cytosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]