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The map label for this gene is adiA [H]

Identifier: 91782354

GI number: 91782354

Start: 1089441

End: 1091726

Strand: Direct

Name: adiA [H]

Synonym: Bxe_A3477

Alternate gene names: 91782354

Gene position: 1089441-1091726 (Clockwise)

Preceding gene: 91782353

Following gene: 91782355

Centisome position: 22.25

GC content: 61.94

Gene sequence:

>2286_bases
ATGAAGTTTCGTTTTCCCGTCGTCATCATCGACGAAGATTTCCGCTCCGAGAACATCTCGGGTTCCGGCATCCGGGCTCT
GGCCGAAGCCATCGAGAAAGAAGGCGCGGAAGTGCTCGGGTTGACGAGCTACGGCGATCTGACTTCGTTCGCGCAGCAGT
CGAGCCGCGCCTCGTGCTTCATCCTTTCGATCGACGATGACGAGCTGCTGCCGTACGTCGATAACGTGGTGGTGGAAGGC
GAGACGCCGGAACTGGCCGCCGCGATCGTCGCGCTGCGCGCGTTCGTGACCGAAGTGCGCCGCCGCAACGCCGACATTCC
GATCTTCCTGTACGGCGAAACGCGCACCTCGCGCCACCTGCCGAACGACATCCTGCGCGAACTGCACGGCTTCATCCACA
TGTTCGAGGACACGCCGGAGTTCGTCGCGCGCCATATCATCCGCGAGACCAAGGTGTATCTGGATTCGCTCGCACCGCCG
TTCTTCAAGGAACTGGTGCAGTACGCGGAAGAAGGCTCGTACTCGTGGCACTGTCCGGGCCACTCGGGCGGCGTCGCGTT
CCTGAAGAGCCCGCTCGGCCAGATGTTCCACCAGTTCTTCGGCGAGAACATGCTGCGCGCGGACGTGTGCAATGCCGTCG
ACGAACTTGGCCAGTTGCTGGACCACACGGGCCCTGTCGCGGCTTCCGAACGCAATGCGGCGCGCATCTTCAGCGCGGAC
CACGTGTTCTTCGTGACCAACGGCACGTCCACGTCGAACAAGATCGTCTGGCACGGCACGGTAGCGCCGGGCGACATCGT
GCTGGTGGACCGCAACTGCCACAAGTCGATCCTGCACGCGATCACCATGACCGGCGCGATTCCGGTGTTCCTCACGCCGA
CGCGCAACAACTTCGGCATCATCGGGCCGATTCCGCGCAGCGAGTTCGAGCCGGAAAACATCAAGAAGAAGATCCTCGCG
AACCCGTTCGCGCGCGAAGCGCTCGCTAAGAATCCGGACCTCAAGCCGCGCATCCTGACCATCACGCAAAGCACGTACGA
CGGCGTAATCTACAACGTCGAGATGATCAAGGAAATGCTCGGCGACTGGCTCGACACGCTGCACTTCGACGAAGCCTGGC
TGCCGCACGCTGAATTCCACGAGTTCTATCAGGACATGCACGCAATCGGCGCGGGCCGTCCGCGTATTGGTGCGATGGTG
TTCGCCACGCACTCCACGCACAAGCTGCTGGCCGGCATTTCGCAGGCTTCGCAGATCGTCGTGCAGGATTCGAAGAACAG
CCGCTTCGACAAGCATCGTTTCAATGAAGCGTATCTGATGCACACGTCGACCAGCCCGCAGTACGCGATCATCGCCTCGT
GCGACGTGGCCGCGGCCATGATGGAAGCGCCGGGCGGCACCGCGCTCGTCGAAGAGTCGATCGCGGAGGCGTTGGACTTC
CGCCGCGCAATGAGCAAGGTCGACGCCGAATACGGCGACGACTGGTTCTTCAAGGTGTGGGGCCCAGACCAGTTCGCCGA
AGAAGGCATCGGCTCGCGCGAAGACTGGATGCTGCGTCCGAACGATCCGTGGCACGGTTTCGGACCGCTCGCCGACGGCT
TCAACATGCTCGACCCGATCAAGGCGACCATCGTTACGCCGGGTCTGGATATGGACGGCGGCTTCGGCGAGTCGGGCATT
CCGGCCGCGATCGTCACGAAGTATCTGGCCGAGCACGGCATCATCGTCGAGAAGACCGGGCTGTATTCGTTCTTCATCAT
GTTCACGATCGGCATCACCAAGGGCCGCTGGAATTCGATGGTCACCGAACTGCAGCAGTTCAAGGACGACTACGACAACA
ACCAGCCGCTGTGGCGCGTGCTGCCCGAGTTCGTCTCGCATCATCCCATGTACGAACGTGTGGGTTTGCGCGATCTGTGC
GAGCAGATTCACAGCGTCTACCGCGCGAACGACATTGCGCGCCTGACGACCGAGATGTACCTGTCGAGCATGGAACCGGC
CATGAAGCCGTCCGATGCGTTCGCCAAGCTCGCGCACCGCGAGATCGACCGCGTGCCTATCGACGAACTGGAAGGCCGCG
TCACGTCGATCCTGCTGACGCCGTATCCGCCGGGCATTCCGCTGCTGATCCCGGGCGAGCGCTTCAACAGGACCATCGTC
AACTATCTGCGTTTCGCGCGCGAGTTCAACGAGCGCTTCCCGGGTTTCCACACGGACATCCACGGGCTGGTCGGCGAAAC
GATCAACGGACGCATCGAATACTTCGTCGATTGCGTTCGCGCCTGA

Upstream 100 bases:

>100_bases
GCCGAGAACGTGACGGCCGCAGCGTACTGAACCACCAGGCATACCGGGTGACCGCTGCAATTGACAGAATGCAGCGGTCG
TTCTTTTTGGAGAATCGCCC

Downstream 100 bases:

>100_bases
CCATGCGGCGAGCGAAGTCCCCGCTGTGGGCCAGCGGCCCGCAGCGCGCGTTCTGCGTGCTGGCGCTGGCTGCGGCGGTG
GTGTTCGGCGCGGCGTCGTT

Product: ornithine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 761; Mature: 761

Protein sequence:

>761_residues
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGAEVLGLTSYGDLTSFAQQSSRASCFILSIDDDELLPYVDNVVVEG
ETPELAAAIVALRAFVTEVRRRNADIPIFLYGETRTSRHLPNDILRELHGFIHMFEDTPEFVARHIIRETKVYLDSLAPP
FFKELVQYAEEGSYSWHCPGHSGGVAFLKSPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSAD
HVFFVTNGTSTSNKIVWHGTVAPGDIVLVDRNCHKSILHAITMTGAIPVFLTPTRNNFGIIGPIPRSEFEPENIKKKILA
NPFAREALAKNPDLKPRILTITQSTYDGVIYNVEMIKEMLGDWLDTLHFDEAWLPHAEFHEFYQDMHAIGAGRPRIGAMV
FATHSTHKLLAGISQASQIVVQDSKNSRFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEAPGGTALVEESIAEALDF
RRAMSKVDAEYGDDWFFKVWGPDQFAEEGIGSREDWMLRPNDPWHGFGPLADGFNMLDPIKATIVTPGLDMDGGFGESGI
PAAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVTELQQFKDDYDNNQPLWRVLPEFVSHHPMYERVGLRDLC
EQIHSVYRANDIARLTTEMYLSSMEPAMKPSDAFAKLAHREIDRVPIDELEGRVTSILLTPYPPGIPLLIPGERFNRTIV
NYLRFAREFNERFPGFHTDIHGLVGETINGRIEYFVDCVRA

Sequences:

>Translated_761_residues
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGAEVLGLTSYGDLTSFAQQSSRASCFILSIDDDELLPYVDNVVVEG
ETPELAAAIVALRAFVTEVRRRNADIPIFLYGETRTSRHLPNDILRELHGFIHMFEDTPEFVARHIIRETKVYLDSLAPP
FFKELVQYAEEGSYSWHCPGHSGGVAFLKSPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSAD
HVFFVTNGTSTSNKIVWHGTVAPGDIVLVDRNCHKSILHAITMTGAIPVFLTPTRNNFGIIGPIPRSEFEPENIKKKILA
NPFAREALAKNPDLKPRILTITQSTYDGVIYNVEMIKEMLGDWLDTLHFDEAWLPHAEFHEFYQDMHAIGAGRPRIGAMV
FATHSTHKLLAGISQASQIVVQDSKNSRFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEAPGGTALVEESIAEALDF
RRAMSKVDAEYGDDWFFKVWGPDQFAEEGIGSREDWMLRPNDPWHGFGPLADGFNMLDPIKATIVTPGLDMDGGFGESGI
PAAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVTELQQFKDDYDNNQPLWRVLPEFVSHHPMYERVGLRDLC
EQIHSVYRANDIARLTTEMYLSSMEPAMKPSDAFAKLAHREIDRVPIDELEGRVTSILLTPYPPGIPLLIPGERFNRTIV
NYLRFAREFNERFPGFHTDIHGLVGETINGRIEYFVDCVRA
>Mature_761_residues
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGAEVLGLTSYGDLTSFAQQSSRASCFILSIDDDELLPYVDNVVVEG
ETPELAAAIVALRAFVTEVRRRNADIPIFLYGETRTSRHLPNDILRELHGFIHMFEDTPEFVARHIIRETKVYLDSLAPP
FFKELVQYAEEGSYSWHCPGHSGGVAFLKSPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSAD
HVFFVTNGTSTSNKIVWHGTVAPGDIVLVDRNCHKSILHAITMTGAIPVFLTPTRNNFGIIGPIPRSEFEPENIKKKILA
NPFAREALAKNPDLKPRILTITQSTYDGVIYNVEMIKEMLGDWLDTLHFDEAWLPHAEFHEFYQDMHAIGAGRPRIGAMV
FATHSTHKLLAGISQASQIVVQDSKNSRFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEAPGGTALVEESIAEALDF
RRAMSKVDAEYGDDWFFKVWGPDQFAEEGIGSREDWMLRPNDPWHGFGPLADGFNMLDPIKATIVTPGLDMDGGFGESGI
PAAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSMVTELQQFKDDYDNNQPLWRVLPEFVSHHPMYERVGLRDLC
EQIHSVYRANDIARLTTEMYLSSMEPAMKPSDAFAKLAHREIDRVPIDELEGRVTSILLTPYPPGIPLLIPGERFNRTIV
NYLRFAREFNERFPGFHTDIHGLVGETINGRIEYFVDCVRA

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=780, Percent_Identity=36.5384615384615, Blast_Score=530, Evalue=1e-151,
Organism=Escherichia coli, GI1790573, Length=723, Percent_Identity=37.2060857538036, Blast_Score=499, Evalue=1e-142,
Organism=Escherichia coli, GI1786384, Length=723, Percent_Identity=37.2060857538036, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI87082193, Length=701, Percent_Identity=32.8102710413695, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1786909, Length=704, Percent_Identity=31.25, Blast_Score=354, Evalue=1e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 85488; Mature: 85488

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGAEVLGLTSYGDLTSFAQQSSRASCF
CCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCEEE
ILSIDDDELLPYVDNVVVEGETPELAAAIVALRAFVTEVRRRNADIPIFLYGETRTSRHL
EEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
PNDILRELHGFIHMFEDTPEFVARHIIRETKVYLDSLAPPFFKELVQYAEEGSYSWHCPG
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCC
HSGGVAFLKSPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSAD
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECC
HVFFVTNGTSTSNKIVWHGTVAPGDIVLVDRNCHKSILHAITMTGAIPVFLTPTRNNFGI
EEEEEECCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHCCEEEEEECCCCCCEE
IGPIPRSEFEPENIKKKILANPFAREALAKNPDLKPRILTITQSTYDGVIYNVEMIKEML
ECCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHH
GDWLDTLHFDEAWLPHAEFHEFYQDMHAIGAGRPRIGAMVFATHSTHKLLAGISQASQIV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCEEE
VQDSKNSRFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEAPGGTALVEESIAEALDF
EECCCCCCCHHHHCCCEEEEEECCCCCEEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHH
RRAMSKVDAEYGDDWFFKVWGPDQFAEEGIGSREDWMLRPNDPWHGFGPLADGFNMLDPI
HHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCCCCEECCCCCCCCCCCHHCCCCHHCCC
KATIVTPGLDMDGGFGESGIPAAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSM
HHEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHH
VTELQQFKDDYDNNQPLWRVLPEFVSHHPMYERVGLRDLCEQIHSVYRANDIARLTTEMY
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSSMEPAMKPSDAFAKLAHREIDRVPIDELEGRVTSILLTPYPPGIPLLIPGERFNRTIV
HHHCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCCCCCCEEECCHHHHHHHH
NYLRFAREFNERFPGFHTDIHGLVGETINGRIEYFVDCVRA
HHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKFRFPVVIIDEDFRSENISGSGIRALAEAIEKEGAEVLGLTSYGDLTSFAQQSSRASCF
CCEECCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCEEE
ILSIDDDELLPYVDNVVVEGETPELAAAIVALRAFVTEVRRRNADIPIFLYGETRTSRHL
EEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
PNDILRELHGFIHMFEDTPEFVARHIIRETKVYLDSLAPPFFKELVQYAEEGSYSWHCPG
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEECCC
HSGGVAFLKSPLGQMFHQFFGENMLRADVCNAVDELGQLLDHTGPVAASERNAARIFSAD
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECC
HVFFVTNGTSTSNKIVWHGTVAPGDIVLVDRNCHKSILHAITMTGAIPVFLTPTRNNFGI
EEEEEECCCCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHCCEEEEEECCCCCCEE
IGPIPRSEFEPENIKKKILANPFAREALAKNPDLKPRILTITQSTYDGVIYNVEMIKEML
ECCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHH
GDWLDTLHFDEAWLPHAEFHEFYQDMHAIGAGRPRIGAMVFATHSTHKLLAGISQASQIV
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCEEE
VQDSKNSRFDKHRFNEAYLMHTSTSPQYAIIASCDVAAAMMEAPGGTALVEESIAEALDF
EECCCCCCCHHHHCCCEEEEEECCCCCEEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHH
RRAMSKVDAEYGDDWFFKVWGPDQFAEEGIGSREDWMLRPNDPWHGFGPLADGFNMLDPI
HHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCCCCEECCCCCCCCCCCHHCCCCHHCCC
KATIVTPGLDMDGGFGESGIPAAIVTKYLAEHGIIVEKTGLYSFFIMFTIGITKGRWNSM
HHEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHH
VTELQQFKDDYDNNQPLWRVLPEFVSHHPMYERVGLRDLCEQIHSVYRANDIARLTTEMY
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSSMEPAMKPSDAFAKLAHREIDRVPIDELEGRVTSILLTPYPPGIPLLIPGERFNRTIV
HHHCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCEEEEEECCCCCCCCEEECCHHHHHHHH
NYLRFAREFNERFPGFHTDIHGLVGETINGRIEYFVDCVRA
HHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]