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The map label for this gene is betA [C]

Identifier: 91782308

GI number: 91782308

Start: 1039593

End: 1041197

Strand: Direct

Name: betA [C]

Synonym: Bxe_A3525

Alternate gene names: 91782308

Gene position: 1039593-1041197 (Clockwise)

Preceding gene: 91782307

Following gene: 91782311

Centisome position: 21.23

GC content: 58.75

Gene sequence:

>1605_bases
ATGACAAAAACGTACGACTATATCGTTGTCGGGGGTGGCTCGTCCGGTTGCGTGGTAGCCACCCGGCTGGTTGAAGCCGG
CTTCGAGGTATTGCTGCTGGAAGCCGGGCCCGTCGACAAGGATATCTACATCCATATGCCCGCCGGCATGAGAAACGCCC
AGAAGTATTCATGGAATTACATGAGCGAAGCGAACCCCGGCTCGGGCGTGCCTCCGATCCACATTCACCAGGGTCGTGTG
CTAGGCGGCGGGAGTTCGGTCAACGGCATGGTGTACGTCCGCGGTTCGGCTCACGACTACGACGACTGGGACAGGATCTA
CGGCTGTACCGGCTGGAGTCACAACGACGTGCTGCCTTACTTTATCCGCTCAGAAGGCAACGAAGTCGTGAGCGGGCCGA
AGCACGGTACGGACGGGAATCTGTGGGTCAGCGAGCACCGCTACCGGCATCCGCTGACGATGGCGTATCTGAGGGCAGCG
CAGGAACTCGGCTATCCGTACATCACCGATATGAGCGGCGCGACCGAGCAGGAGGGCGTGGGCTTCTGGCAGTGCACGAT
CCACGAAGGCAAACGCGGTAGTACGGCCCGGGCCTACCTGCAGCGGGTCATCAAAAGCGATCTGCTGACGGTCGTGACCG
GAGCGACCGCCAGGAAGGTGCAGATAGAAAACGGTCGGGCCTGCGGGGTGCGCTACGCTCGCAACGGCAATTCCGTTACC
GATGCGGTTGCGACGAGGGAAGTGATTCTCACGGCCGGTGCATTCGAGACGCCTAAGCTCCTGATGCTCTCCGGTATCGG
TCCGGCGCAGCATCTGAACGAGTTCGGCATCGGGACCATTGCCGACAGTCCGCAGGTCGGTAAGAACTTCCAGGATCACC
TGATGGTCTCCATCACGGCCGAAACGCCGGGCATTCCTAGCTTCCTGCGCGAAGGAGAGGGCCTGCGCAAGATCGCGAAT
GGGCTGGAATGGCTGACCTTCAACCACGACGGCGTGGTCTCTTCGAACGTGCTGGAGGGCGGAGGCTATTTCGACATAAA
CGACGATGGACGAATCGATACGCAGTTGTTCGTTTTTCCTTTCTATGAAGGCAAGCGCGACGGAAACTGGACGAAAGCCG
ATCAGATTCCGGACGGCATGGCGCTCAAGGTCGGCCACGTCTATCCCGAGTCGCGCGGAGAGGTGCTGCTTGGCGGACCC
CGGCCCGACGACAAGATCCGTCTGAAAGGCAATTACCTGTCGGCCGACGGCGACCTGGACTTGCAGGTGAAGGCGTTCAA
GCTGGGGCTGAAATTTTTCGATGCTCCGTCGTTGAAGAAAATTACCCGGAACGTGGCGCCGAAGTTCTCGGACGACCACG
AAATAGCCGATTACGTACGAAAGAACTGTACGACGATATTTCATCCCACTTCGACTTGCCGTATGGGAAATTCCCCGCAG
AGTTCGGTGGTCGATCTTACGCTGCGCGTGTGGGGAATTGCCAATCTCCGCATCGCTGATGCCTCCGTTATGCCACACAT
AGTCAGTGGCAATACAAACGCACCGACGATCATGATCGCGGAGCGAGCGGCAGAAATGATTATTCATGCGTCGTCCCATT
CTTGA

Upstream 100 bases:

>100_bases
TCGAAGGCTTGATGCCCTATCTCGAGACCAAGACCGTGCTGCTGGAAAAACTGCCGTCGCATCATCAAACAACGCAACCT
AGAATAGTGGATTCGCCAGC

Downstream 100 bases:

>100_bases
AATCGTGCAGCAGGGAGCGAACGAACCGACTCGCGATCTGAATCGCTGACACGGTTATTGACACATTGTGATTTCGGTTT
CGATGTCCGGGAAAGGGCAC

Product: putative glucose-methanol-choline (GMC)oxidoreductase

Products: NA

Alternate protein names: SDH [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MTKTYDYIVVGGGSSGCVVATRLVEAGFEVLLLEAGPVDKDIYIHMPAGMRNAQKYSWNYMSEANPGSGVPPIHIHQGRV
LGGGSSVNGMVYVRGSAHDYDDWDRIYGCTGWSHNDVLPYFIRSEGNEVVSGPKHGTDGNLWVSEHRYRHPLTMAYLRAA
QELGYPYITDMSGATEQEGVGFWQCTIHEGKRGSTARAYLQRVIKSDLLTVVTGATARKVQIENGRACGVRYARNGNSVT
DAVATREVILTAGAFETPKLLMLSGIGPAQHLNEFGIGTIADSPQVGKNFQDHLMVSITAETPGIPSFLREGEGLRKIAN
GLEWLTFNHDGVVSSNVLEGGGYFDINDDGRIDTQLFVFPFYEGKRDGNWTKADQIPDGMALKVGHVYPESRGEVLLGGP
RPDDKIRLKGNYLSADGDLDLQVKAFKLGLKFFDAPSLKKITRNVAPKFSDDHEIADYVRKNCTTIFHPTSTCRMGNSPQ
SSVVDLTLRVWGIANLRIADASVMPHIVSGNTNAPTIMIAERAAEMIIHASSHS

Sequences:

>Translated_534_residues
MTKTYDYIVVGGGSSGCVVATRLVEAGFEVLLLEAGPVDKDIYIHMPAGMRNAQKYSWNYMSEANPGSGVPPIHIHQGRV
LGGGSSVNGMVYVRGSAHDYDDWDRIYGCTGWSHNDVLPYFIRSEGNEVVSGPKHGTDGNLWVSEHRYRHPLTMAYLRAA
QELGYPYITDMSGATEQEGVGFWQCTIHEGKRGSTARAYLQRVIKSDLLTVVTGATARKVQIENGRACGVRYARNGNSVT
DAVATREVILTAGAFETPKLLMLSGIGPAQHLNEFGIGTIADSPQVGKNFQDHLMVSITAETPGIPSFLREGEGLRKIAN
GLEWLTFNHDGVVSSNVLEGGGYFDINDDGRIDTQLFVFPFYEGKRDGNWTKADQIPDGMALKVGHVYPESRGEVLLGGP
RPDDKIRLKGNYLSADGDLDLQVKAFKLGLKFFDAPSLKKITRNVAPKFSDDHEIADYVRKNCTTIFHPTSTCRMGNSPQ
SSVVDLTLRVWGIANLRIADASVMPHIVSGNTNAPTIMIAERAAEMIIHASSHS
>Mature_533_residues
TKTYDYIVVGGGSSGCVVATRLVEAGFEVLLLEAGPVDKDIYIHMPAGMRNAQKYSWNYMSEANPGSGVPPIHIHQGRVL
GGGSSVNGMVYVRGSAHDYDDWDRIYGCTGWSHNDVLPYFIRSEGNEVVSGPKHGTDGNLWVSEHRYRHPLTMAYLRAAQ
ELGYPYITDMSGATEQEGVGFWQCTIHEGKRGSTARAYLQRVIKSDLLTVVTGATARKVQIENGRACGVRYARNGNSVTD
AVATREVILTAGAFETPKLLMLSGIGPAQHLNEFGIGTIADSPQVGKNFQDHLMVSITAETPGIPSFLREGEGLRKIANG
LEWLTFNHDGVVSSNVLEGGGYFDINDDGRIDTQLFVFPFYEGKRDGNWTKADQIPDGMALKVGHVYPESRGEVLLGGPR
PDDKIRLKGNYLSADGDLDLQVKAFKLGLKFFDAPSLKKITRNVAPKFSDDHEIADYVRKNCTTIFHPTSTCRMGNSPQS
SVVDLTLRVWGIANLRIADASVMPHIVSGNTNAPTIMIAERAAEMIIHASSHS

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=542, Percent_Identity=40.0369003690037, Blast_Score=330, Evalue=3e-90,
Organism=Escherichia coli, GI1786503, Length=536, Percent_Identity=35.0746268656716, Blast_Score=278, Evalue=8e-76,
Organism=Caenorhabditis elegans, GI17532301, Length=555, Percent_Identity=35.6756756756757, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI45549471, Length=570, Percent_Identity=33.3333333333333, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI45551458, Length=570, Percent_Identity=33.3333333333333, Blast_Score=257, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24642042, Length=573, Percent_Identity=35.4275741710297, Blast_Score=251, Evalue=8e-67,
Organism=Drosophila melanogaster, GI18859995, Length=572, Percent_Identity=33.5664335664336, Blast_Score=247, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24642059, Length=564, Percent_Identity=31.5602836879433, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24642037, Length=571, Percent_Identity=33.6252189141856, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24642039, Length=578, Percent_Identity=32.6989619377163, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24650267, Length=578, Percent_Identity=31.3148788927336, Blast_Score=234, Evalue=9e-62,
Organism=Drosophila melanogaster, GI24642048, Length=566, Percent_Identity=32.5088339222615, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI17137792, Length=564, Percent_Identity=32.6241134751773, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24642055, Length=584, Percent_Identity=30.9931506849315, Blast_Score=228, Evalue=6e-60,
Organism=Drosophila melanogaster, GI24642051, Length=579, Percent_Identity=30.9153713298791, Blast_Score=212, Evalue=5e-55,
Organism=Drosophila melanogaster, GI18859993, Length=577, Percent_Identity=30.3292894280763, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI24642035, Length=571, Percent_Identity=30.4728546409807, Blast_Score=205, Evalue=8e-53,
Organism=Drosophila melanogaster, GI24642057, Length=580, Percent_Identity=27.9310344827586, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24645930, Length=551, Percent_Identity=25.2268602540835, Blast_Score=112, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.32 [H]

Molecular weight: Translated: 58295; Mature: 58163

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00623 GMC_OXRED_1 ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTYDYIVVGGGSSGCVVATRLVEAGFEVLLLEAGPVDKDIYIHMPAGMRNAQKYSWNY
CCCEEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCC
MSEANPGSGVPPIHIHQGRVLGGGSSVNGMVYVRGSAHDYDDWDRIYGCTGWSHNDVLPY
CCCCCCCCCCCCEEEECCEEEECCCCCCCEEEEECCCCCCCCHHHHEEECCCCCCCCCEE
FIRSEGNEVVSGPKHGTDGNLWVSEHRYRHPLTMAYLRAAQELGYPYITDMSGATEQEGV
EEECCCCCEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCC
GFWQCTIHEGKRGSTARAYLQRVIKSDLLTVVTGATARKVQIENGRACGVRYARNGNSVT
EEEEEEEECCCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCEEEEEEECCCCCHH
DAVATREVILTAGAFETPKLLMLSGIGPAQHLNEFGIGTIADSPQVGKNFQDHLMVSITA
HHHHHEEEEEECCCCCCCCEEEEECCCHHHHHHHCCCEEECCCCHHCCCCCCEEEEEEEE
ETPGIPSFLREGEGLRKIANGLEWLTFNHDGVVSSNVLEGGGYFDINDDGRIDTQLFVFP
CCCCCHHHHHCCCHHHHHHCCCEEEEECCCCCEECCEECCCCEEEECCCCCEEEEEEEEE
FYEGKRDGNWTKADQIPDGMALKVGHVYPESRGEVLLGGPRPDDKIRLKGNYLSADGDLD
EECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCCCEEEEECCEEECCCCCE
LQVKAFKLGLKFFDAPSLKKITRNVAPKFSDDHEIADYVRKNCTTIFHPTSTCRMGNSPQ
EEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCC
SSVVDLTLRVWGIANLRIADASVMPHIVSGNTNAPTIMIAERAAEMIIHASSHS
CCEEEEEEEEEEEEEEEEECCCCCCEEECCCCCCCEEEEECCCEEEEEEECCCC
>Mature Secondary Structure 
TKTYDYIVVGGGSSGCVVATRLVEAGFEVLLLEAGPVDKDIYIHMPAGMRNAQKYSWNY
CCEEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCC
MSEANPGSGVPPIHIHQGRVLGGGSSVNGMVYVRGSAHDYDDWDRIYGCTGWSHNDVLPY
CCCCCCCCCCCCEEEECCEEEECCCCCCCEEEEECCCCCCCCHHHHEEECCCCCCCCCEE
FIRSEGNEVVSGPKHGTDGNLWVSEHRYRHPLTMAYLRAAQELGYPYITDMSGATEQEGV
EEECCCCCEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCC
GFWQCTIHEGKRGSTARAYLQRVIKSDLLTVVTGATARKVQIENGRACGVRYARNGNSVT
EEEEEEEECCCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCEEEEEEECCCCCHH
DAVATREVILTAGAFETPKLLMLSGIGPAQHLNEFGIGTIADSPQVGKNFQDHLMVSITA
HHHHHEEEEEECCCCCCCCEEEEECCCHHHHHHHCCCEEECCCCHHCCCCCCEEEEEEEE
ETPGIPSFLREGEGLRKIANGLEWLTFNHDGVVSSNVLEGGGYFDINDDGRIDTQLFVFP
CCCCCHHHHHCCCHHHHHHCCCEEEEECCCCCEECCEECCCCEEEECCCCCEEEEEEEEE
FYEGKRDGNWTKADQIPDGMALKVGHVYPESRGEVLLGGPRPDDKIRLKGNYLSADGDLD
EECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCCCEEEEECCEEECCCCCE
LQVKAFKLGLKFFDAPSLKKITRNVAPKFSDDHEIADYVRKNCTTIFHPTSTCRMGNSPQ
EEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCC
SSVVDLTLRVWGIANLRIADASVMPHIVSGNTNAPTIMIAERAAEMIIHASSHS
CCEEEEEEEEEEEEEEEEECCCCCCEEECCCCCCCEEEEECCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9023923 [H]