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The map label for this gene is pcm [H]

Identifier: 91782158

GI number: 91782158

Start: 872625

End: 873278

Strand: Reverse

Name: pcm [H]

Synonym: Bxe_A3677

Alternate gene names: 91782158

Gene position: 873278-872625 (Counterclockwise)

Preceding gene: 91782165

Following gene: 91782157

Centisome position: 17.84

GC content: 63.76

Gene sequence:

>654_bases
ATGAACATCGAGCAAGCGCGTTTCAACATGATCGAACAGCAGATCCGCCCCTGGGAAGTGCTCGACCAGGACGTGCTGAA
TCTGTTGTCGATCGTCAAGCGTGAAAACTTCGTCCCCGCCGTCTATCGCGACCTGGCCTTCGTCGACTTCGAAGTGCCGC
TGCCGGCCGGCCAGCACATGCTGGCGCCGCGCGTCGAGGCGCGCGTGCTGCAGGAACTGGCGGTGAAGAAACACGAAAGC
GTGCTCGAAATCGGCGCGGGCTCGGGTTACATGGCCGCGTTGCTCGCGCACCGCGCGCAGCACGTGCTGACGGTCGACAT
CGAACCGGAACTGGCGGAACTGGCGAAAACCAACCTGATCGCCAACGGCGTGCTGAACGCCGAAGTCGCCACCGGCGACG
CTTCCCGCGGCTGGCCCGCCGCCGCGCCGTACGACGTGATCTGCGTGTCGGGCGGCCTGCCGGTGCTACCGCAGGAAATT
CTCGACCATCTGAAGATCGGCGGCCGTCTGGCCGCGTTCGTCGGCACCGCGCCGGTCATGAAGGCGCAGATCATCACGCG
TATCGACGAGAAGCAGTACCGCATTGCCGACGTATTCGAAACGTATGTCGAGCCGCTCATCAACGCCGTGCAGCCGTCGC
GTTTCAAGTTCTGA

Upstream 100 bases:

>100_bases
CGCAGTTACCCTGACGCGCCTTGCGTGCCGAGTTGTCCTTGCGAGGCCGGCGGTCAGTGGCACATCGCAAAACTCGCCAA
ACCACAGAGCCGAATCCACC

Downstream 100 bases:

>100_bases
TTGGCACGCTGACCCGGACGGCGGGCCTGCCCGCCGTCCCTGAATTGAACCGGATGTCCTCCTGATGCAAAACCTGACCG
CTCCGGCGCTCGCCGAATGG

Product: protein-L-isoaspartate(D-aspartate)O- methyltransferase

Products: NA

Alternate protein names: L-isoaspartyl protein carboxyl methyltransferase; Protein L-isoaspartyl methyltransferase; Protein-beta-aspartate methyltransferase; PIMT [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNIEQARFNMIEQQIRPWEVLDQDVLNLLSIVKRENFVPAVYRDLAFVDFEVPLPAGQHMLAPRVEARVLQELAVKKHES
VLEIGAGSGYMAALLAHRAQHVLTVDIEPELAELAKTNLIANGVLNAEVATGDASRGWPAAAPYDVICVSGGLPVLPQEI
LDHLKIGGRLAAFVGTAPVMKAQIITRIDEKQYRIADVFETYVEPLINAVQPSRFKF

Sequences:

>Translated_217_residues
MNIEQARFNMIEQQIRPWEVLDQDVLNLLSIVKRENFVPAVYRDLAFVDFEVPLPAGQHMLAPRVEARVLQELAVKKHES
VLEIGAGSGYMAALLAHRAQHVLTVDIEPELAELAKTNLIANGVLNAEVATGDASRGWPAAAPYDVICVSGGLPVLPQEI
LDHLKIGGRLAAFVGTAPVMKAQIITRIDEKQYRIADVFETYVEPLINAVQPSRFKF
>Mature_217_residues
MNIEQARFNMIEQQIRPWEVLDQDVLNLLSIVKRENFVPAVYRDLAFVDFEVPLPAGQHMLAPRVEARVLQELAVKKHES
VLEIGAGSGYMAALLAHRAQHVLTVDIEPELAELAKTNLIANGVLNAEVATGDASRGWPAAAPYDVICVSGGLPVLPQEI
LDHLKIGGRLAAFVGTAPVMKAQIITRIDEKQYRIADVFETYVEPLINAVQPSRFKF

Specific function: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins [H]

COG id: COG2518

COG function: function code O; Protein-L-isoaspartate carboxylmethyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789100, Length=209, Percent_Identity=33.0143540669856, Blast_Score=100, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000682 [H]

Pfam domain/function: PF01135 PCMT [H]

EC number: =2.1.1.77 [H]

Molecular weight: Translated: 23972; Mature: 23972

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEQARFNMIEQQIRPWEVLDQDVLNLLSIVKRENFVPAVYRDLAFVDFEVPLPAGQHM
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCCCCCH
LAPRVEARVLQELAVKKHESVLEIGAGSGYMAALLAHRAQHVLTVDIEPELAELAKTNLI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHH
ANGVLNAEVATGDASRGWPAAAPYDVICVSGGLPVLPQEILDHLKIGGRLAAFVGTAPVM
HCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHCCHHHH
KAQIITRIDEKQYRIADVFETYVEPLINAVQPSRFKF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNIEQARFNMIEQQIRPWEVLDQDVLNLLSIVKRENFVPAVYRDLAFVDFEVPLPAGQHM
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCCCCCH
LAPRVEARVLQELAVKKHESVLEIGAGSGYMAALLAHRAQHVLTVDIEPELAELAKTNLI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHH
ANGVLNAEVATGDASRGWPAAAPYDVICVSGGLPVLPQEILDHLKIGGRLAAFVGTAPVM
HCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHCCHHHH
KAQIITRIDEKQYRIADVFETYVEPLINAVQPSRFKF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA