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The map label for this gene is xasA [C]

Identifier: 91782019

GI number: 91782019

Start: 721738

End: 723258

Strand: Direct

Name: xasA [C]

Synonym: Bxe_A3825

Alternate gene names: 91782019

Gene position: 721738-723258 (Clockwise)

Preceding gene: 91782018

Following gene: 91782024

Centisome position: 14.74

GC content: 63.84

Gene sequence:

>1521_bases
ATGGACAACACAGTCACCGCCGCGGCCGCAGCGCCGGCAGCGGACGCCGCAAAACGCGGCAAGTATCTGAGCGTGACGGC
GATCGGTCTGATGACGGCCGCCGCCGTGGTCACGAGTCTGCGCGGACTTCCTTTACTGGCGAAGGAGGAGATGACGATGT
TCGTCTATCTCGCCTTCACGGTCGTTTTCTACCTGATCCCAGCGTCGCTGATTTCCGCCGAACTGGGCGGCGCGTTCGCC
GACCGGCCCGGCGGCATCTACACGTGGGTCGCGGAGGCGTTCGGCACGCGCTGGGGTTTTCTCGCGATCTGGCTGCAATG
GATCCAGAACGTCGTGTGGTATCCGGTCGCGCTGACCTTCGGCGCGGCGGCGCTCGCCTATACGATCGGCCGGCCGGAAC
TGGCGAAGAACGGCGTGTATGTCGGCATCTTCTGCATCGTCGCGTATTGGCTCGCGACGTGGGTCGTGCTGCAAGGCGTC
GAAGTCTTCGCGAGGATCGCCAACTGGACCTTCGTGATCGGCACCATCGTGCCGGGCCTCGTGCTGCTTGCGCTGCTGGG
CTACTGGATCAGCAGCGGACACCCGCTCGGCTGGCAACACCTGAACGATGCGGCTCTCTCGCAAGACGGTCACGCGCGCT
TCTGGCCCGCGATTCACGGCTTCGGCACGATCTCGTTTCTGGCCGGCATCATGTTGCTGTTTGCCGGTGTGGAGGTGCAG
GCGGTTCATGTGATCGACATGCGCAGCCCGAGTCGCGGTTATCCCGCGGCGATCGGACTGGGTGCGCTGATTTCGGTGCT
GATTTTCGCGCTCGGCGCGTTGCCGATTGCAGCGATCTTGCCGTACGAGAAGATATCGCTGCAATCCGGCGTGTTCGACG
CATTCAGCGCGGTGCTGGTGGACATCTGGCACATGAACTGGGCTGTGTCGGCGTTGTCGCTGCTGGTCGGCGTCGGGGCG
ATCAGTGGGGTGCTGGCCTGGCTCGGCAGTCCGTCGCGCGGCCTGCTTGAAACCGCGCACGAAGGCGAATTGCCGCCGAT
CCTTCAGGCTAAGAATCGCAAGGGCATGCCCACTCATATTCTGCTGGTGCAAGGCCTGATCGTGACGGTCATCTCGTGCT
TCTACTTCGTGATCCGTGATGTGTCGGTCGCGTTCTTTCTGATCTCCGCCATGACGATCGCGCTCTACCTGATCGCCTAC
ATGCTGATGTACGCGGCGGCGATCCGGCTGCGCTACTCGGCACCGGCCTTGCCGCGTCCGTTCACGGTGCCCGGCGGCTT
TGCCGGCATGTGGCTGACCGCCGGCATCGGCTTTGCCGGGGTGCTGTTCAGCTTCGTCGTGTCGTTCTTTCCGCCGGATC
AGTTGCCGGTCGGTTCGCCTTGGCTTTATACGGGACTCGTCGTTATCGGCATTGTGGTGTTCGCGGGGATTCCCCTGATC
ATCCACCACGTGCGCCGCAGCGACTGGGCGAGCGTGCACGACACGCCGCGCGTTCCTCCGGCCGTGATCCCGGTGGAGTA
G

Upstream 100 bases:

>100_bases
GCACGCCATCGGGCATCTGACGAAGAATCCGGTGCTGCATTCGAGCGCCGGTCCGACCTTCCACCACAATTGATATCGCC
TGTTCACAGGGGCACACGAA

Downstream 100 bases:

>100_bases
GTACGCGCGTGCGTGGCTGGATCGTCAGGTAAGCCAGGTGAAGCTGTCTGACTGGACTTCGGGGCAGCGTGTCCACGAGT
GTCCGTCAGCAAGGCCTCTC

Product: glutamate/gamma-aminobutyrate anti-porter

Products: L-glutamate [Cytoplasm]; 4-aminobutyrate [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MDNTVTAAAAAPAADAAKRGKYLSVTAIGLMTAAAVVTSLRGLPLLAKEEMTMFVYLAFTVVFYLIPASLISAELGGAFA
DRPGGIYTWVAEAFGTRWGFLAIWLQWIQNVVWYPVALTFGAAALAYTIGRPELAKNGVYVGIFCIVAYWLATWVVLQGV
EVFARIANWTFVIGTIVPGLVLLALLGYWISSGHPLGWQHLNDAALSQDGHARFWPAIHGFGTISFLAGIMLLFAGVEVQ
AVHVIDMRSPSRGYPAAIGLGALISVLIFALGALPIAAILPYEKISLQSGVFDAFSAVLVDIWHMNWAVSALSLLVGVGA
ISGVLAWLGSPSRGLLETAHEGELPPILQAKNRKGMPTHILLVQGLIVTVISCFYFVIRDVSVAFFLISAMTIALYLIAY
MLMYAAAIRLRYSAPALPRPFTVPGGFAGMWLTAGIGFAGVLFSFVVSFFPPDQLPVGSPWLYTGLVVIGIVVFAGIPLI
IHHVRRSDWASVHDTPRVPPAVIPVE

Sequences:

>Translated_506_residues
MDNTVTAAAAAPAADAAKRGKYLSVTAIGLMTAAAVVTSLRGLPLLAKEEMTMFVYLAFTVVFYLIPASLISAELGGAFA
DRPGGIYTWVAEAFGTRWGFLAIWLQWIQNVVWYPVALTFGAAALAYTIGRPELAKNGVYVGIFCIVAYWLATWVVLQGV
EVFARIANWTFVIGTIVPGLVLLALLGYWISSGHPLGWQHLNDAALSQDGHARFWPAIHGFGTISFLAGIMLLFAGVEVQ
AVHVIDMRSPSRGYPAAIGLGALISVLIFALGALPIAAILPYEKISLQSGVFDAFSAVLVDIWHMNWAVSALSLLVGVGA
ISGVLAWLGSPSRGLLETAHEGELPPILQAKNRKGMPTHILLVQGLIVTVISCFYFVIRDVSVAFFLISAMTIALYLIAY
MLMYAAAIRLRYSAPALPRPFTVPGGFAGMWLTAGIGFAGVLFSFVVSFFPPDQLPVGSPWLYTGLVVIGIVVFAGIPLI
IHHVRRSDWASVHDTPRVPPAVIPVE
>Mature_506_residues
MDNTVTAAAAAPAADAAKRGKYLSVTAIGLMTAAAVVTSLRGLPLLAKEEMTMFVYLAFTVVFYLIPASLISAELGGAFA
DRPGGIYTWVAEAFGTRWGFLAIWLQWIQNVVWYPVALTFGAAALAYTIGRPELAKNGVYVGIFCIVAYWLATWVVLQGV
EVFARIANWTFVIGTIVPGLVLLALLGYWISSGHPLGWQHLNDAALSQDGHARFWPAIHGFGTISFLAGIMLLFAGVEVQ
AVHVIDMRSPSRGYPAAIGLGALISVLIFALGALPIAAILPYEKISLQSGVFDAFSAVLVDIWHMNWAVSALSLLVGVGA
ISGVLAWLGSPSRGLLETAHEGELPPILQAKNRKGMPTHILLVQGLIVTVISCFYFVIRDVSVAFFLISAMTIALYLIAY
MLMYAAAIRLRYSAPALPRPFTVPGGFAGMWLTAGIGFAGVLFSFVVSFFPPDQLPVGSPWLYTGLVVIGIVVFAGIPLI
IHHVRRSDWASVHDTPRVPPAVIPVE

Specific function: Probable Amino Acid Transporter. Involved In Extreme Acid Resistance. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787768, Length=481, Percent_Identity=28.0665280665281, Blast_Score=197, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 54252; Mature: 54252

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNTVTAAAAAPAADAAKRGKYLSVTAIGLMTAAAVVTSLRGLPLLAKEEMTMFVYLAFT
CCCCCCHHHCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VVFYLIPASLISAELGGAFADRPGGIYTWVAEAFGTRWGFLAIWLQWIQNVVWYPVALTF
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GAAALAYTIGRPELAKNGVYVGIFCIVAYWLATWVVLQGVEVFARIANWTFVIGTIVPGL
HHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLALLGYWISSGHPLGWQHLNDAALSQDGHARFWPAIHGFGTISFLAGIMLLFAGVEVQ
HHHHHHHHHHCCCCCCCHHHCCHHHHCCCCCCEECHHHHCCHHHHHHHHHHHHHCCCCEE
AVHVIDMRSPSRGYPAAIGLGALISVLIFALGALPIAAILPYEKISLQSGVFDAFSAVLV
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
DIWHMNWAVSALSLLVGVGAISGVLAWLGSPSRGLLETAHEGELPPILQAKNRKGMPTHI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHCCCCCCCCCHHH
LLVQGLIVTVISCFYFVIRDVSVAFFLISAMTIALYLIAYMLMYAAAIRLRYSAPALPRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FTVPGGFAGMWLTAGIGFAGVLFSFVVSFFPPDQLPVGSPWLYTGLVVIGIVVFAGIPLI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IHHVRRSDWASVHDTPRVPPAVIPVE
HHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDNTVTAAAAAPAADAAKRGKYLSVTAIGLMTAAAVVTSLRGLPLLAKEEMTMFVYLAFT
CCCCCCHHHCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VVFYLIPASLISAELGGAFADRPGGIYTWVAEAFGTRWGFLAIWLQWIQNVVWYPVALTF
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GAAALAYTIGRPELAKNGVYVGIFCIVAYWLATWVVLQGVEVFARIANWTFVIGTIVPGL
HHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLALLGYWISSGHPLGWQHLNDAALSQDGHARFWPAIHGFGTISFLAGIMLLFAGVEVQ
HHHHHHHHHHCCCCCCCHHHCCHHHHCCCCCCEECHHHHCCHHHHHHHHHHHHHCCCCEE
AVHVIDMRSPSRGYPAAIGLGALISVLIFALGALPIAAILPYEKISLQSGVFDAFSAVLV
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
DIWHMNWAVSALSLLVGVGAISGVLAWLGSPSRGLLETAHEGELPPILQAKNRKGMPTHI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHCCCCCCCCCHHH
LLVQGLIVTVISCFYFVIRDVSVAFFLISAMTIALYLIAYMLMYAAAIRLRYSAPALPRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FTVPGGFAGMWLTAGIGFAGVLFSFVVSFFPPDQLPVGSPWLYTGLVVIGIVVFAGIPLI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
IHHVRRSDWASVHDTPRVPPAVIPVE
HHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-aminobutyrate [Cytoplasm]; L-glutamate [Periplasm] [C]

Specific reaction: 4-aminobutyrate [Cytoplasm] + L-glutamate [Periplasm] = L-glutamate [Cytoplasm] + 4-aminobutyrate [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8366052 [H]