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The map label for this gene is fnr [H]

Identifier: 91781918

GI number: 91781918

Start: 602624

End: 603352

Strand: Direct

Name: fnr [H]

Synonym: Bxe_A3927

Alternate gene names: 91781918

Gene position: 602624-603352 (Clockwise)

Preceding gene: 91781912

Following gene: 91781920

Centisome position: 12.31

GC content: 62.41

Gene sequence:

>729_bases
ATGAAGGATGACGTATCCGCACCCTCTCGCTACCGGCCTTCGATTTTCGCAGTGCCATTCCAGCGGCACGGCGACGGGAC
GGCGGTCGAATTGCTATCCCCGTCCGAACAGGACGCGCTGATCGCCATTTCCCGACTCGTCACGGTCCGGCGGCATACGG
TGCTTTATCCGGAAGGCGGTGACGCGCGTTTCGCCTACAACATCGTTAGCGGAGTCGCGGAAACCTATCAGCTCCTTCCG
AACGGAGACAAGCGGATCACCGCGTTTCTTTTTCCGCGGGATCTGATGGGACTCAGCGAAAACGGCGCCTATGTGGCGAC
CGCCCAGTCGCTCACGCCCCTGGTCGCGTACAGGATACCGGTCGAGGCGCTCGCGGAGATTCTCGAACGCGATCCGCGTC
TGGACATCGGGCTGCTCTGCAAACTGTGCCATGAACTGCGGCGCTCGCAACATCACACGATAACGGTATCGAAAAACGAG
GCGCCAGCCAGGCTGGCCAGCTTCCTGGTCTGGATTCAGCACGCCTACCCCGAGGAGGGGCGCGCCGAGGGAGAAGTGAT
GTTGCCGATGTCCCGGCACGACATTGCCGATTACCTCGGTCTGTCGGTTGAATCCGTCAGCCGCGGCCTACATGTTCTGG
AGGCGCAGGACGCGGTGCGCCGCAAGGGGCCGAGGCTCGTAACGGTGCTGGACCCCGCGAAACTTCGCAGGTTGGCGGGA
CAGGATTGA

Upstream 100 bases:

>100_bases
GGCCGCAGCGCCGCTGAATTCGCACCCGGCCTGTCCGGTTTCGTCGAACGCTTGCCGAACCGGCTTTCCCGAGAAGATAA
ACCTCGAAAGAAAGAACATC

Downstream 100 bases:

>100_bases
GTCCGCCGTCCCCGGCCGCCGGTCGTTTCCCGACCGCAACCACGGAGCCGGCGCACTATCAGAACGAAGTCGCCACCATC
GCCAGCGTGATCAGCAGCAT

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKDDVSAPSRYRPSIFAVPFQRHGDGTAVELLSPSEQDALIAISRLVTVRRHTVLYPEGGDARFAYNIVSGVAETYQLLP
NGDKRITAFLFPRDLMGLSENGAYVATAQSLTPLVAYRIPVEALAEILERDPRLDIGLLCKLCHELRRSQHHTITVSKNE
APARLASFLVWIQHAYPEEGRAEGEVMLPMSRHDIADYLGLSVESVSRGLHVLEAQDAVRRKGPRLVTVLDPAKLRRLAG
QD

Sequences:

>Translated_242_residues
MKDDVSAPSRYRPSIFAVPFQRHGDGTAVELLSPSEQDALIAISRLVTVRRHTVLYPEGGDARFAYNIVSGVAETYQLLP
NGDKRITAFLFPRDLMGLSENGAYVATAQSLTPLVAYRIPVEALAEILERDPRLDIGLLCKLCHELRRSQHHTITVSKNE
APARLASFLVWIQHAYPEEGRAEGEVMLPMSRHDIADYLGLSVESVSRGLHVLEAQDAVRRKGPRLVTVLDPAKLRRLAG
QD
>Mature_242_residues
MKDDVSAPSRYRPSIFAVPFQRHGDGTAVELLSPSEQDALIAISRLVTVRRHTVLYPEGGDARFAYNIVSGVAETYQLLP
NGDKRITAFLFPRDLMGLSENGAYVATAQSLTPLVAYRIPVEALAEILERDPRLDIGLLCKLCHELRRSQHHTITVSKNE
APARLASFLVWIQHAYPEEGRAEGEVMLPMSRHDIADYLGLSVESVSRGLHVLEAQDAVRRKGPRLVTVLDPAKLRRLAG
QD

Specific function: Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metab

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=200, Percent_Identity=29.5, Blast_Score=93, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26857; Mature: 26857

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDDVSAPSRYRPSIFAVPFQRHGDGTAVELLSPSEQDALIAISRLVTVRRHTVLYPEGG
CCCCCCCCCCCCCCEEEECCEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHEEEEECCC
DARFAYNIVSGVAETYQLLPNGDKRITAFLFPRDLMGLSENGAYVATAQSLTPLVAYRIP
CCEEHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHCCCCCCCCEEEEHHHHCHHHHHCCC
VEALAEILERDPRLDIGLLCKLCHELRRSQHHTITVSKNEAPARLASFLVWIQHAYPEEG
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCC
RAEGEVMLPMSRHDIADYLGLSVESVSRGLHVLEAQDAVRRKGPRLVTVLDPAKLRRLAG
CCCCCEEECCHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCEEEEEECHHHHHHHCC
QD
CC
>Mature Secondary Structure
MKDDVSAPSRYRPSIFAVPFQRHGDGTAVELLSPSEQDALIAISRLVTVRRHTVLYPEGG
CCCCCCCCCCCCCCEEEECCEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHEEEEECCC
DARFAYNIVSGVAETYQLLPNGDKRITAFLFPRDLMGLSENGAYVATAQSLTPLVAYRIP
CCEEHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHCCCCCCCCEEEEHHHHCHHHHHCCC
VEALAEILERDPRLDIGLLCKLCHELRRSQHHTITVSKNEAPARLASFLVWIQHAYPEEG
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCC
RAEGEVMLPMSRHDIADYLGLSVESVSRGLHVLEAQDAVRRKGPRLVTVLDPAKLRRLAG
CCCCCEEECCHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCEEEEEECHHHHHHHCC
QD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA