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The map label for this gene is pntAA [H]

Identifier: 91781837

GI number: 91781837

Start: 508080

End: 509222

Strand: Direct

Name: pntAA [H]

Synonym: Bxe_A4008

Alternate gene names: 91781837

Gene position: 508080-509222 (Clockwise)

Preceding gene: 91781828

Following gene: 91781838

Centisome position: 10.38

GC content: 67.19

Gene sequence:

>1143_bases
ATGCACATCGGAGTGCCAGCCGAGACGCGCGCGCACGAAACCCGCGTCGCCGCGACGCCCGAGACGGTCAAGAAGTACGT
GACCCAGGGCCACCGGGTCACGATCCAGAGCGGCGCCGGCACCGGCGCAAGCTTTCCTGACGACGCCTTTACGGCCGCCG
GCGCGGAGATCGTCGACGCCGCGGCCGCTTTCGGCGCCGATCTCGTTCTCAAGGTGCAGTCGCCGACCGACGCCGAACTG
CCGCTTCTGAAGCGCGGCGCGGTGCTGGTCGGCATGCTCGATCCTTTTAATACCGAAAACTCATCAAAGCTGGCGGCAGC
CGGCGTCACCGCGTTCGCGCTCGAAGCCGCGCCGCGCACCACGCGTGCGCAGAGCCTCGACGTGCTGAGCTCGCAGGCCA
ACATTGCCGGGTATAAGGCGGTGCTGCTCGCGGCCACGCTGTACCCGCGCTTCATGCCGATGCTGATGACCGCCGCCGGC
ACCGTGAAGGCCGCGCGCGTGCTGATCCTGGGCGCGGGCGTGGCGGGCTTGCAGGCGATTGCGACTGCGAAGCGTCTGGG
CGCCGTGATCGAAGCATCTGACGTGCGTCCCGCGGTCAAGGAGCAGATCGAATCGCTCGGTGCGAAATTTCTCGACGTGC
CCTACGAAACCGACGAGGAGCGTGAAGCCGCCCAAGGCGTCGGCGGTTATGCGCGGCCTATGCCGCCATCGTGGCTCACG
CGTCAGTCGGCGCTAGTTCATGAGCGCGCCAGACAGGCTGACGTGGTGATTTCCACCGCGCTGATTCCGGGGCGCGCCGC
GCCGACCTTGATCTCGGTGGAAACCGTGCAGGCGATGAAACCCGGCTCCGTGCTGGTCGATCTCGCGGCGGGACGCGGAG
CCGAGTACGAAGGCCGGCGCGGCGGCAACTGTCCGTTGACCGAAGCGGATCAGGTGGTGATCAGGCACGGCGTGTCCATC
GTCGGCTATACGAATCTGGCCTCGATGGTGCCCGCCGACGCGTCGTCCCTCTACGCGCGCAACCTGCTCGATTTCCTCAA
GCTGATCATCACGAAGGAAGGCGCCCTGAACATCGATCTCGCGGACGACATCGTCGCGGCCACGCTGCTGGCCCGCGACG
GCGAAGTCGCGCGCAAAGCCTGA

Upstream 100 bases:

>100_bases
GCCCGTTTCGGTTAAAGTGAGGCGTTAGCCGTTGCACTTGCAAGCCGGCGTGCCTCGTCGGCGGATCTGTCGTAAAACAG
GAAGTCGAGGAGGAACAACG

Downstream 100 bases:

>100_bases
GCAGTCAATTGCATGGGACCGAGGTAAGCGCCGACGCGCTTACTCTGGCCGACATCGAATCAATACATAGGAGAGCGGCG
ATGGAAGTCATCAACCACAC

Product: putative NAD(P) transhydrogenase, alpha subunit

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 1; Proton-translocating transhydrogenase component 1; Pyridine nucleotide transhydrogenase subunit alpha 1; dI [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MHIGVPAETRAHETRVAATPETVKKYVTQGHRVTIQSGAGTGASFPDDAFTAAGAEIVDAAAAFGADLVLKVQSPTDAEL
PLLKRGAVLVGMLDPFNTENSSKLAAAGVTAFALEAAPRTTRAQSLDVLSSQANIAGYKAVLLAATLYPRFMPMLMTAAG
TVKAARVLILGAGVAGLQAIATAKRLGAVIEASDVRPAVKEQIESLGAKFLDVPYETDEEREAAQGVGGYARPMPPSWLT
RQSALVHERARQADVVISTALIPGRAAPTLISVETVQAMKPGSVLVDLAAGRGAEYEGRRGGNCPLTEADQVVIRHGVSI
VGYTNLASMVPADASSLYARNLLDFLKLIITKEGALNIDLADDIVAATLLARDGEVARKA

Sequences:

>Translated_380_residues
MHIGVPAETRAHETRVAATPETVKKYVTQGHRVTIQSGAGTGASFPDDAFTAAGAEIVDAAAAFGADLVLKVQSPTDAEL
PLLKRGAVLVGMLDPFNTENSSKLAAAGVTAFALEAAPRTTRAQSLDVLSSQANIAGYKAVLLAATLYPRFMPMLMTAAG
TVKAARVLILGAGVAGLQAIATAKRLGAVIEASDVRPAVKEQIESLGAKFLDVPYETDEEREAAQGVGGYARPMPPSWLT
RQSALVHERARQADVVISTALIPGRAAPTLISVETVQAMKPGSVLVDLAAGRGAEYEGRRGGNCPLTEADQVVIRHGVSI
VGYTNLASMVPADASSLYARNLLDFLKLIITKEGALNIDLADDIVAATLLARDGEVARKA
>Mature_380_residues
MHIGVPAETRAHETRVAATPETVKKYVTQGHRVTIQSGAGTGASFPDDAFTAAGAEIVDAAAAFGADLVLKVQSPTDAEL
PLLKRGAVLVGMLDPFNTENSSKLAAAGVTAFALEAAPRTTRAQSLDVLSSQANIAGYKAVLLAATLYPRFMPMLMTAAG
TVKAARVLILGAGVAGLQAIATAKRLGAVIEASDVRPAVKEQIESLGAKFLDVPYETDEEREAAQGVGGYARPMPPSWLT
RQSALVHERARQADVVISTALIPGRAAPTLISVETVQAMKPGSVLVDLAAGRGAEYEGRRGGNCPLTEADQVVIRHGVSI
VGYTNLASMVPADASSLYARNLLDFLKLIITKEGALNIDLADDIVAATLLARDGEVARKA

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=391, Percent_Identity=39.386189258312, Blast_Score=258, Evalue=6e-69,
Organism=Homo sapiens, GI122939153, Length=391, Percent_Identity=39.386189258312, Blast_Score=258, Evalue=6e-69,
Organism=Escherichia coli, GI1787887, Length=383, Percent_Identity=44.3864229765013, Blast_Score=305, Evalue=3e-84,
Organism=Caenorhabditis elegans, GI17550456, Length=377, Percent_Identity=39.2572944297082, Blast_Score=266, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 39571; Mature: 39571

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIGVPAETRAHETRVAATPETVKKYVTQGHRVTIQSGAGTGASFPDDAFTAAGAEIVDA
CCCCCCCCCCCCCCEECCCHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHCCHHHHHH
AAAFGADLVLKVQSPTDAELPLLKRGAVLVGMLDPFNTENSSKLAAAGVTAFALEAAPRT
HHHCCCEEEEEECCCCCCCCCHHHCCCEEEEECCCCCCCCCCHHHHHCHHHEEECCCCCC
TRAQSLDVLSSQANIAGYKAVLLAATLYPRFMPMLMTAAGTVKAARVLILGAGVAGLQAI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEEECCHHHHHHH
ATAKRLGAVIEASDVRPAVKEQIESLGAKFLDVPYETDEEREAAQGVGGYARPMPPSWLT
HHHHHHHHHHCCCCCCHHHHHHHHHHCHHEECCCCCCCHHHHHHHCCCCCCCCCCHHHHH
RQSALVHERARQADVVISTALIPGRAAPTLISVETVQAMKPGSVLVDLAAGRGAEYEGRR
HHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEHHHHHCCCCCEEEEECCCCCCCCCCCC
GGNCPLTEADQVVIRHGVSIVGYTNLASMVPADASSLYARNLLDFLKLIITKEGALNIDL
CCCCCCCHHHHHHHHCCCEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEH
ADDIVAATLLARDGEVARKA
HHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MHIGVPAETRAHETRVAATPETVKKYVTQGHRVTIQSGAGTGASFPDDAFTAAGAEIVDA
CCCCCCCCCCCCCCEECCCHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHCCHHHHHH
AAAFGADLVLKVQSPTDAELPLLKRGAVLVGMLDPFNTENSSKLAAAGVTAFALEAAPRT
HHHCCCEEEEEECCCCCCCCCHHHCCCEEEEECCCCCCCCCCHHHHHCHHHEEECCCCCC
TRAQSLDVLSSQANIAGYKAVLLAATLYPRFMPMLMTAAGTVKAARVLILGAGVAGLQAI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEEECCHHHHHHH
ATAKRLGAVIEASDVRPAVKEQIESLGAKFLDVPYETDEEREAAQGVGGYARPMPPSWLT
HHHHHHHHHHCCCCCCHHHHHHHHHHCHHEECCCCCCCHHHHHHHCCCCCCCCCCHHHHH
RQSALVHERARQADVVISTALIPGRAAPTLISVETVQAMKPGSVLVDLAAGRGAEYEGRR
HHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEHHHHHCCCCCEEEEECCCCCCCCCCCC
GGNCPLTEADQVVIRHGVSIVGYTNLASMVPADASSLYARNLLDFLKLIITKEGALNIDL
CCCCCCCHHHHHHHHCCCEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEH
ADDIVAATLLARDGEVARKA
HHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]