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The map label for this gene is ctaD [H]

Identifier: 91781676

GI number: 91781676

Start: 326465

End: 328078

Strand: Direct

Name: ctaD [H]

Synonym: Bxe_A4170

Alternate gene names: 91781676

Gene position: 326465-328078 (Clockwise)

Preceding gene: 91781675

Following gene: 91781677

Centisome position: 6.67

GC content: 62.21

Gene sequence:

>1614_bases
ATGTCTAGCATCGGACACGATGTAGTCGCGGGCCACGAGCACGTGCACGGCGACCATGCCCACGAAACGCCGCATGGCTG
GCGCCGTTGGCTGTTCGCAACCAATCACAAGGACATCGGTACGCTGTACCTGATCTTCTCGTTCACCATGTTCCTCTCCG
GGGGCGTGATGGCGCTGATGATCCGTGCCGAACTGTTCGAGCCGGGCTTGCAGATCATGCGTCCCGAGTTCTTCAACCAG
TTGACCACCATGCACGGCCTGATCATGGTGTTCGGCGCGATCATGCCGGCCTTCGTCGGCTTCGCGAACTGGATGGTGCC
GCTGCAGATCGGCGCATCGGACATGGCTTTCGCCCGCATGAACAACTTCAGCTTCTGGCTTTTGCCGGTGGCGGCTGTCC
TGCTGGTCGGTTCGTTCTTCGCACCCGGCGGCGCGACCGCCGCGGGCTGGACGCTCTACGCGCCGTTGTCCACGCAGATG
GGCCCGGGCATGGACTTCGCGATTTTCGCGGTCCACCTGATGGGCGCTTCGTCGATCATGGGCGGGATCAACATCGTCGT
GACGATCCTGAACATGCGCGCCCCCGGCCTCACGCTGATGAAGATGCCGATGTTCGTCTGGACGTGGCTGATCACCGCGT
ACCTGCTGATCGCCGTGATGCCGGTTCTGGCAGGCGCGATCACTATGGTGCTGTTCGACCGTCACTTCGGCACGTCGTTC
TTCAACGCGGCAGGCGGCGGCGACCCGGTCATGTACCAGCACATCTTCTGGTTCTTCGGGCACCCCGAGGTGTACATCAT
GATCCTGCCGGCGTTCGGGATCGTCTCGCAGGTGATTCCGGCGTTCGCGCGCAAGCCGCTGTTCGGCTATAGCTCTATGG
TGTATGCAACCTCGTCGATCGCGATTCTGTCGTTCATGGTCTGGGCGCACCACATGTTCGCCACCGGCATGCCGGTGACG
GGCCAGCTGTTCTTCATGTACGCAACCATGCTGATCGCCGTGCCGACGGGCGTGAAGGTGTTCAACTGGGTCGCGACGAT
GTGGCGCGGTTCGCTGAGCTTCGAAACGCCTATGCTGTTCGCGGTCGGCTTCCTGCTGGTGTTCACGTTCGGCGGCCTGT
CGGGCCTGATGCTGGCTATGGCGCCGCTCGACATCCAGTATCACGGTACTTATTTCGTGGTGGCGCACTTCCACTATGTG
CTGGTGGCGGGCTCGCTCTTCGCGCTGTTCGCCGGCTGGTATTACTGGGCGCCGAAGTGGACCGGCTGGATGTACAACGA
AACGCGCGGCAAGATTCACTTCTGGGCGTCGATGTTCTTCTTCAACCTCGCGTTCCTGCCCATGCACTTCGTCGGCCTTG
CCGGTATGCCGCGTCGTTACGCTGACTATCCGGCACAGTTCACGGACTGGAACCAGGTCATCACGATCGGCGCGTTCGGC
TTCGGTCTGGCGCAGGTCTACTTCCTGTTCGCGGTTGCACTGCCGGCCTATCGTGGCGGTGGCGAACTCGAAAAGGCCGG
CGACAAGCCGTGGGACGGCGCAACGGGCCTCGAATGGACCGTGCCGAGCCCGGCTCCGTTCCACACGTTCGAAAACCCGC
CGACCGTCGAGTAA

Upstream 100 bases:

>100_bases
CGGGCGGCAGCGACGCGAAAGAAGCCCGGCGTGTTCAGATCAGCCCGGCTGCCTGACGTGTTCATGGTCAGCACCGCAGT
ATTCGCTTTAGGAGATTGTC

Downstream 100 bases:

>100_bases
TTGGCGTACGGTGGGGTGCCGGCTCGGGTGGCGCAGCAGCGCGCCGCCGGAGCCGGCAGCCACGAAAGTCGCGGCGGTAC
CTGAGTCACGAAACGTATTC

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MSSIGHDVVAGHEHVHGDHAHETPHGWRRWLFATNHKDIGTLYLIFSFTMFLSGGVMALMIRAELFEPGLQIMRPEFFNQ
LTTMHGLIMVFGAIMPAFVGFANWMVPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQM
GPGMDFAIFAVHLMGASSIMGGINIVVTILNMRAPGLTLMKMPMFVWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSF
FNAAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATSSIAILSFMVWAHHMFATGMPVT
GQLFFMYATMLIAVPTGVKVFNWVATMWRGSLSFETPMLFAVGFLLVFTFGGLSGLMLAMAPLDIQYHGTYFVVAHFHYV
LVAGSLFALFAGWYYWAPKWTGWMYNETRGKIHFWASMFFFNLAFLPMHFVGLAGMPRRYADYPAQFTDWNQVITIGAFG
FGLAQVYFLFAVALPAYRGGGELEKAGDKPWDGATGLEWTVPSPAPFHTFENPPTVE

Sequences:

>Translated_537_residues
MSSIGHDVVAGHEHVHGDHAHETPHGWRRWLFATNHKDIGTLYLIFSFTMFLSGGVMALMIRAELFEPGLQIMRPEFFNQ
LTTMHGLIMVFGAIMPAFVGFANWMVPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQM
GPGMDFAIFAVHLMGASSIMGGINIVVTILNMRAPGLTLMKMPMFVWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSF
FNAAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATSSIAILSFMVWAHHMFATGMPVT
GQLFFMYATMLIAVPTGVKVFNWVATMWRGSLSFETPMLFAVGFLLVFTFGGLSGLMLAMAPLDIQYHGTYFVVAHFHYV
LVAGSLFALFAGWYYWAPKWTGWMYNETRGKIHFWASMFFFNLAFLPMHFVGLAGMPRRYADYPAQFTDWNQVITIGAFG
FGLAQVYFLFAVALPAYRGGGELEKAGDKPWDGATGLEWTVPSPAPFHTFENPPTVE
>Mature_536_residues
SSIGHDVVAGHEHVHGDHAHETPHGWRRWLFATNHKDIGTLYLIFSFTMFLSGGVMALMIRAELFEPGLQIMRPEFFNQL
TTMHGLIMVFGAIMPAFVGFANWMVPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMG
PGMDFAIFAVHLMGASSIMGGINIVVTILNMRAPGLTLMKMPMFVWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFF
NAAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATSSIAILSFMVWAHHMFATGMPVTG
QLFFMYATMLIAVPTGVKVFNWVATMWRGSLSFETPMLFAVGFLLVFTFGGLSGLMLAMAPLDIQYHGTYFVVAHFHYVL
VAGSLFALFAGWYYWAPKWTGWMYNETRGKIHFWASMFFFNLAFLPMHFVGLAGMPRRYADYPAQFTDWNQVITIGAFGF
GLAQVYFLFAVALPAYRGGGELEKAGDKPWDGATGLEWTVPSPAPFHTFENPPTVE

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=48.3365949119374, Blast_Score=449, Evalue=1e-126,
Organism=Escherichia coli, GI1786634, Length=518, Percent_Identity=40.9266409266409, Blast_Score=378, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6226519, Length=531, Percent_Identity=46.8926553672316, Blast_Score=480, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=50.1547987616099, Blast_Score=330, Evalue=4e-91,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=47.3684210526316, Blast_Score=217, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59630; Mature: 59499

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.9 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIGHDVVAGHEHVHGDHAHETPHGWRRWLFATNHKDIGTLYLIFSFTMFLSGGVMALM
CCCCCCCHHCCCCCCCCCCCCCCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHCCHHHHH
IRAELFEPGLQIMRPEFFNQLTTMHGLIMVFGAIMPAFVGFANWMVPLQIGASDMAFARM
HHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHH
NNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGPGMDFAIFAVHLMGASSIM
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
GGINIVVTILNMRAPGLTLMKMPMFVWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSF
CCHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
FNAAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATSSI
HCCCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AILSFMVWAHHMFATGMPVTGQLFFMYATMLIAVPTGVKVFNWVATMWRGSLSFETPMLF
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHH
AVGFLLVFTFGGLSGLMLAMAPLDIQYHGTYFVVAHFHYVLVAGSLFALFAGWYYWAPKW
HHHHHHHHHHHCHHHHHHHHCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCC
TGWMYNETRGKIHFWASMFFFNLAFLPMHFVGLAGMPRRYADYPAQFTDWNQVITIGAFG
CCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCEEEEEHHH
FGLAQVYFLFAVALPAYRGGGELEKAGDKPWDGATGLEWTVPSPAPFHTFENPPTVE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSIGHDVVAGHEHVHGDHAHETPHGWRRWLFATNHKDIGTLYLIFSFTMFLSGGVMALM
CCCCCCHHCCCCCCCCCCCCCCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHCCHHHHH
IRAELFEPGLQIMRPEFFNQLTTMHGLIMVFGAIMPAFVGFANWMVPLQIGASDMAFARM
HHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHH
NNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGPGMDFAIFAVHLMGASSIM
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
GGINIVVTILNMRAPGLTLMKMPMFVWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSF
CCHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
FNAAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKPLFGYSSMVYATSSI
HCCCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AILSFMVWAHHMFATGMPVTGQLFFMYATMLIAVPTGVKVFNWVATMWRGSLSFETPMLF
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHH
AVGFLLVFTFGGLSGLMLAMAPLDIQYHGTYFVVAHFHYVLVAGSLFALFAGWYYWAPKW
HHHHHHHHHHHCHHHHHHHHCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCC
TGWMYNETRGKIHFWASMFFFNLAFLPMHFVGLAGMPRRYADYPAQFTDWNQVITIGAFG
CCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCEEEEEHHH
FGLAQVYFLFAVALPAYRGGGELEKAGDKPWDGATGLEWTVPSPAPFHTFENPPTVE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]