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The map label for this gene is dacC [H]

Identifier: 91781628

GI number: 91781628

Start: 279077

End: 280333

Strand: Direct

Name: dacC [H]

Synonym: Bxe_A4218

Alternate gene names: 91781628

Gene position: 279077-280333 (Clockwise)

Preceding gene: 91781627

Following gene: 91781629

Centisome position: 5.7

GC content: 62.85

Gene sequence:

>1257_bases
ATGTATTTTTCTGCACGAATCGACCCTATGCGTTTCTCCATCTCCGGCCGCACGTCCTTCCCTTCTGTTGCTTCCTTCGT
TTCCCCTACGCTTGCGCGTGCCGTCACTCTCGGCGTCGTGTTGCCGGCCACGCTCGCCGCCAGCACGGCGTTCGCACAGG
TGCCGCCGCCGGCAGTGAACGCGCGCTCGTGGGTGCTAGTCGACGCCACCAGCAATCAGGTGCTCGCCTCGGGCAATGCC
GACGAGCGCGTGGAACCCGCATCGCTCACCAAGCTGATGACGGCGTACCTCGTCTTCGAAGCACTGCAGACGAAGAAAAT
CAACATGGACCAGACGGTCATGCCGAGCGAGGCCGTGCGCCGCGTGCGCACCGACGAATCGCGCATGTTCATCGAAGCGA
ACAAGCCGGTGACCGTGCACGATCTGGTGTACGGCATGATCGTCCAGTCGGGTAACGACGCGGCGATCGCGCTGGCCGAA
CTGGTCGGCGGCAGCGAGTCGCAGTTTGTCAACATGATGAACACGGAAGCGCAACGCCTCGGCATGAAGCACACGCATTT
CGCCGACGTGAACGGCATGCCCGACCCGCAGCACTACACGACCGCGGGCGACCTCGCGATCCTGTCGGCGCGTCTGATCC
GCGATTTTCCTGACTACTACAACATCTTCTCGGTCAAGGAATTCACGTACAACAAGATCAAGCAGCCGAACCGCAACCGC
CTGCTGTGGATCGACCCGACGGTAGATGGTCTGAAGACCGGTCACACGCAAGCCGCCGGCTACTGCCTGATCGCGAGCGC
GAAGCGTTCGCTGCCGGGCACGACCGACGCGTCGCGCCGCCTCGTCTCGGTCATGATGGGCGAGACCAAGGAACACGACC
GCGTGCAGGACAGCCTGAAGATGCTGAACTACGGCTATAGCGCGTACGACACGGTGCGTCTGTACAAGGCGAATCAGGTG
GTGGGCACGCCGCGCGTCTACAAGGGTGCGCAGGACACCGTGCAGATCGGCGTGAAGAGCGACCAGTACATCACCGTGCC
GAAGGGCATGGGCGACAAGGTGAAGCCGCAGATCGAGCAGATCGATCCGCTGATCGCGCCGCTCGCGAATGGTCAGCAGG
TCGGCACGGTCAAGCTGGTCGCCGACGGCAAGGTGCTGGCGCAGTTCCCGGTGGTGGCCTTGCAGGCCGTGCCGCAAGCC
GGCGTGGTCGGCCGCGTGTGGGATTCGCTGATGCTCATGTTCAACAAGAAGAAGTAA

Upstream 100 bases:

>100_bases
CGCGAACCGATCGCGTGGCCGGAAGTCCAATGGGCGCCGTGCCGTTTTTACGGCCGGACGCTCGCCGACCGGCTCTTCCA
AACAATGCGCCCTGCGCGCG

Downstream 100 bases:

>100_bases
GAGCCTGATTGCAATGACCGCTGTTTCCGATGTTTCGTCCGATCCGATTGTCTATCTGAACGGTGAGTTGGTGCCGTTGT
CCGAAGCGCGCGTGCCGGTT

Product: penicillin-binding protein 6

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MYFSARIDPMRFSISGRTSFPSVASFVSPTLARAVTLGVVLPATLAASTAFAQVPPPAVNARSWVLVDATSNQVLASGNA
DERVEPASLTKLMTAYLVFEALQTKKINMDQTVMPSEAVRRVRTDESRMFIEANKPVTVHDLVYGMIVQSGNDAAIALAE
LVGGSESQFVNMMNTEAQRLGMKHTHFADVNGMPDPQHYTTAGDLAILSARLIRDFPDYYNIFSVKEFTYNKIKQPNRNR
LLWIDPTVDGLKTGHTQAAGYCLIASAKRSLPGTTDASRRLVSVMMGETKEHDRVQDSLKMLNYGYSAYDTVRLYKANQV
VGTPRVYKGAQDTVQIGVKSDQYITVPKGMGDKVKPQIEQIDPLIAPLANGQQVGTVKLVADGKVLAQFPVVALQAVPQA
GVVGRVWDSLMLMFNKKK

Sequences:

>Translated_418_residues
MYFSARIDPMRFSISGRTSFPSVASFVSPTLARAVTLGVVLPATLAASTAFAQVPPPAVNARSWVLVDATSNQVLASGNA
DERVEPASLTKLMTAYLVFEALQTKKINMDQTVMPSEAVRRVRTDESRMFIEANKPVTVHDLVYGMIVQSGNDAAIALAE
LVGGSESQFVNMMNTEAQRLGMKHTHFADVNGMPDPQHYTTAGDLAILSARLIRDFPDYYNIFSVKEFTYNKIKQPNRNR
LLWIDPTVDGLKTGHTQAAGYCLIASAKRSLPGTTDASRRLVSVMMGETKEHDRVQDSLKMLNYGYSAYDTVRLYKANQV
VGTPRVYKGAQDTVQIGVKSDQYITVPKGMGDKVKPQIEQIDPLIAPLANGQQVGTVKLVADGKVLAQFPVVALQAVPQA
GVVGRVWDSLMLMFNKKK
>Mature_418_residues
MYFSARIDPMRFSISGRTSFPSVASFVSPTLARAVTLGVVLPATLAASTAFAQVPPPAVNARSWVLVDATSNQVLASGNA
DERVEPASLTKLMTAYLVFEALQTKKINMDQTVMPSEAVRRVRTDESRMFIEANKPVTVHDLVYGMIVQSGNDAAIALAE
LVGGSESQFVNMMNTEAQRLGMKHTHFADVNGMPDPQHYTTAGDLAILSARLIRDFPDYYNIFSVKEFTYNKIKQPNRNR
LLWIDPTVDGLKTGHTQAAGYCLIASAKRSLPGTTDASRRLVSVMMGETKEHDRVQDSLKMLNYGYSAYDTVRLYKANQV
VGTPRVYKGAQDTVQIGVKSDQYITVPKGMGDKVKPQIEQIDPLIAPLANGQQVGTVKLVADGKVLAQFPVVALQAVPQA
GVVGRVWDSLMLMFNKKK

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=385, Percent_Identity=41.8181818181818, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1786851, Length=365, Percent_Identity=39.1780821917808, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI87082022, Length=388, Percent_Identity=37.3711340206186, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI87082054, Length=221, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 45736; Mature: 45736

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFSARIDPMRFSISGRTSFPSVASFVSPTLARAVTLGVVLPATLAASTAFAQVPPPAVN
CEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ARSWVLVDATSNQVLASGNADERVEPASLTKLMTAYLVFEALQTKKINMDQTVMPSEAVR
CCEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
RVRTDESRMFIEANKPVTVHDLVYGMIVQSGNDAAIALAELVGGSESQFVNMMNTEAQRL
HHCCCCCEEEEECCCCEEHHHHHHHHHEECCCCHHEEHHHHHCCCHHHHHHHHHHHHHHC
GMKHTHFADVNGMPDPQHYTTAGDLAILSARLIRDFPDYYNIFSVKEFTYNKIKQPNRNR
CCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCEEEEHHHHHHHHCCCCCCE
LLWIDPTVDGLKTGHTQAAGYCLIASAKRSLPGTTDASRRLVSVMMGETKEHDRVQDSLK
EEEECCCCCCHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
MLNYGYSAYDTVRLYKANQVVGTPRVYKGAQDTVQIGVKSDQYITVPKGMGDKVKPQIEQ
HHHCCCCCEEEEEEEECCCEECCCHHHCCCCCEEEEEECCCCEEEECCCCCCCCCCHHHH
IDPLIAPLANGQQVGTVKLVADGKVLAQFPVVALQAVPQAGVVGRVWDSLMLMFNKKK
HCHHHHHCCCCCCEEEEEEEECCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYFSARIDPMRFSISGRTSFPSVASFVSPTLARAVTLGVVLPATLAASTAFAQVPPPAVN
CEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ARSWVLVDATSNQVLASGNADERVEPASLTKLMTAYLVFEALQTKKINMDQTVMPSEAVR
CCEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
RVRTDESRMFIEANKPVTVHDLVYGMIVQSGNDAAIALAELVGGSESQFVNMMNTEAQRL
HHCCCCCEEEEECCCCEEHHHHHHHHHEECCCCHHEEHHHHHCCCHHHHHHHHHHHHHHC
GMKHTHFADVNGMPDPQHYTTAGDLAILSARLIRDFPDYYNIFSVKEFTYNKIKQPNRNR
CCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCEEEEHHHHHHHHCCCCCCE
LLWIDPTVDGLKTGHTQAAGYCLIASAKRSLPGTTDASRRLVSVMMGETKEHDRVQDSLK
EEEECCCCCCHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
MLNYGYSAYDTVRLYKANQVVGTPRVYKGAQDTVQIGVKSDQYITVPKGMGDKVKPQIEQ
HHHCCCCCEEEEEEEECCCEECCCHHHCCCCCEEEEEECCCCEEEECCCCCCCCCCHHHH
IDPLIAPLANGQQVGTVKLVADGKVLAQFPVVALQAVPQAGVVGRVWDSLMLMFNKKK
HCHHHHHCCCCCCEEEEEEEECCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]