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The map label for this gene is coaX

Identifier: 91781619

GI number: 91781619

Start: 270916

End: 271728

Strand: Reverse

Name: coaX

Synonym: Bxe_A4227

Alternate gene names: 91781619

Gene position: 271728-270916 (Counterclockwise)

Preceding gene: 91781620

Following gene: 91781618

Centisome position: 5.55

GC content: 69.13

Gene sequence:

>813_bases
ATGACGAGCGGCGCGCCCTGTTTGCTGATCGACGCGGGCAATAGCCGCATCAAGTGGGCACTGGTGCAGGCGGGCGGTTC
GCAGATTGCGAGCGGCGCGCTGACGCACGGCGGCGAGCATCAGCCGGACTGGCTGAGCTTGCCCACGCCGGGCGGTGCAT
GGTTGTCGAACGTTGCGGGCGAAAGCGTCGCCAGGCGGATTGCCGCATTGCTCGAAGCGCGCTGGCCGCAACTGCCGCTC
ACGACCATCAGCGCCTGCGCGCAGCAATGCGGCGTGACCAACAGCTACACTGCGCCGCATATGCTCGGCAGCGACCGCTG
GGCCGGCCTGATCGGCGCGCACGCGGCGTTTCCGGGCGAACATCTGCTGATCGCGACGTTCGGCACGGCAACCACGCTCG
AGGCATTGCGCGCGGACGGCTGCTTTGTCGGCGGCCTGATCGCGCCTGGCTGGACTTTGATGATGCGCTCGCTGGGCGAG
CACACGGCACAGTTGCCGACACTCGACGCCAGCGCGGCACGCGGCCTGCTGGACGGCAGTACGCGTGACGCGGCACGCCG
CGGCCCGTTCTTTGCAACCGATACGCCGCGCTCGTTGTCCGCCGGCTGCACATTGGCGCAAGCGGGCCTCGTCGAACGCA
TGTGGCGCGATCTGCAGGACGAGTGGCAGGTGCCGGTGCGGCTCGTGGTCAGCGGCGGCGCGGTGGACGAAGTGGCGAGC
GCACTGAAAGTGCCGCATACTCGCCACGATTCGCTCGTGCTGTCCGGTCTTGCGCTGATTGCCGCCGGGCGCGCAGCGGA
ACGTGGGGCCTGA

Upstream 100 bases:

>100_bases
CGGGTGTGGACGAACAGGGTCAGTTGCTGCTCGATACCGCAAGCGGTCGCCAGACTGTGGCGACCGGCGACGTCTCCCTG
CGTCTCGCCGACGGTGCTGC

Downstream 100 bases:

>100_bases
ATCACGGCCACATGGATCGCGGCGGAATAGCCACGGGATAACGGCGGCTCAACTTCTGGACGGGGAAAACCAACAATGCT
GCGCTGGCTGATCGCCATAC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTSGAPCLLIDAGNSRIKWALVQAGGSQIASGALTHGGEHQPDWLSLPTPGGAWLSNVAGESVARRIAALLEARWPQLPL
TTISACAQQCGVTNSYTAPHMLGSDRWAGLIGAHAAFPGEHLLIATFGTATTLEALRADGCFVGGLIAPGWTLMMRSLGE
HTAQLPTLDASAARGLLDGSTRDAARRGPFFATDTPRSLSAGCTLAQAGLVERMWRDLQDEWQVPVRLVVSGGAVDEVAS
ALKVPHTRHDSLVLSGLALIAAGRAAERGA

Sequences:

>Translated_270_residues
MTSGAPCLLIDAGNSRIKWALVQAGGSQIASGALTHGGEHQPDWLSLPTPGGAWLSNVAGESVARRIAALLEARWPQLPL
TTISACAQQCGVTNSYTAPHMLGSDRWAGLIGAHAAFPGEHLLIATFGTATTLEALRADGCFVGGLIAPGWTLMMRSLGE
HTAQLPTLDASAARGLLDGSTRDAARRGPFFATDTPRSLSAGCTLAQAGLVERMWRDLQDEWQVPVRLVVSGGAVDEVAS
ALKVPHTRHDSLVLSGLALIAAGRAAERGA
>Mature_269_residues
TSGAPCLLIDAGNSRIKWALVQAGGSQIASGALTHGGEHQPDWLSLPTPGGAWLSNVAGESVARRIAALLEARWPQLPLT
TISACAQQCGVTNSYTAPHMLGSDRWAGLIGAHAAFPGEHLLIATFGTATTLEALRADGCFVGGLIAPGWTLMMRSLGEH
TAQLPTLDASAARGLLDGSTRDAARRGPFFATDTPRSLSAGCTLAQAGLVERMWRDLQDEWQVPVRLVVSGGAVDEVASA
LKVPHTRHDSLVLSGLALIAAGRAAERGA

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_BURXL (Q146G6)

Other databases:

- EMBL:   CP000270
- RefSeq:   YP_556825.1
- ProteinModelPortal:   Q146G6
- GeneID:   4004271
- GenomeReviews:   CP000270_GR
- KEGG:   bxe:Bxe_A4227
- HOGENOM:   HBG634537
- OMA:   RTTIRSR
- ProtClustDB:   PRK13328
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28053; Mature: 27922

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: ACT_SITE 105-105 BINDING 96-96 BINDING 129-129 BINDING 195-195

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGAPCLLIDAGNSRIKWALVQAGGSQIASGALTHGGEHQPDWLSLPTPGGAWLSNVAG
CCCCCCEEEEECCCCEEEEEEEECCCHHHHHCHHCCCCCCCCCEEECCCCCHHHHHHHHH
ESVARRIAALLEARWPQLPLTTISACAQQCGVTNSYTAPHMLGSDRWAGLIGAHAAFPGE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
HLLIATFGTATTLEALRADGCFVGGLIAPGWTLMMRSLGEHTAQLPTLDASAARGLLDGS
EEEEEECCCHHHHHHHHCCCCEECCCHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
TRDAARRGPFFATDTPRSLSAGCTLAQAGLVERMWRDLQDEWQVPVRLVVSGGAVDEVAS
CHHHHHCCCEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHH
ALKVPHTRHDSLVLSGLALIAAGRAAERGA
HHCCCCCCCHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure 
TSGAPCLLIDAGNSRIKWALVQAGGSQIASGALTHGGEHQPDWLSLPTPGGAWLSNVAG
CCCCCEEEEECCCCEEEEEEEECCCHHHHHCHHCCCCCCCCCEEECCCCCHHHHHHHHH
ESVARRIAALLEARWPQLPLTTISACAQQCGVTNSYTAPHMLGSDRWAGLIGAHAAFPGE
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
HLLIATFGTATTLEALRADGCFVGGLIAPGWTLMMRSLGEHTAQLPTLDASAARGLLDGS
EEEEEECCCHHHHHHHHCCCCEECCCHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
TRDAARRGPFFATDTPRSLSAGCTLAQAGLVERMWRDLQDEWQVPVRLVVSGGAVDEVAS
CHHHHHCCCEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHH
ALKVPHTRHDSLVLSGLALIAAGRAAERGA
HHCCCCCCCHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA