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The map label for this gene is yjcE [H]

Identifier: 91781552

GI number: 91781552

Start: 195498

End: 197153

Strand: Reverse

Name: yjcE [H]

Synonym: Bxe_A4293

Alternate gene names: 91781552

Gene position: 197153-195498 (Counterclockwise)

Preceding gene: 91781555

Following gene: 91781550

Centisome position: 4.03

GC content: 66.36

Gene sequence:

>1656_bases
ATGGATATTGTCTTTACCGTACTGATTCTTTTGCTCGCCGTCGCCGCATCGGGCGTCGTCATCCGCATCCTGCCCATCGC
GTTGCCGCTGCCGCTCGTGCAGATCGCGATCGGCGCGCTGCTCGCGTGGCCGAAGCTCGGGCTGCACGTCACCTTCGATC
CGGAAATTTTCATGATGCTGTTCATTCCGCCTCTGCTGTTCGCGGACGGATGGCGCATTCCCAAGCGCGAGTTCTTCATG
GCGCGCCGCTCGATCCTGATGCTCGCGCTCGGGCTGGTCTTCGTGACGGTGCTGGTGGTCGGCTACTTCGTGCATGCACT
GGTGCCGTCGATCTCGCTGCCGGTGGCGTTCGCGCTGGCCGCGGTGCTGTCGCCGACCGATGCGGTGGCGCTGTCCGGCA
TCGTCGGCAAGGGCAAGATTCCCGGGCGGCTCATGCACATACTGGAAGGCGAAGCGTTGATGAACGACGCGTCGGGACTG
GTCGCGCTGAAGTTCGCGATTGCCGCGGCGCTGACCGGCGTGTTTTCGCTGCGCGACGCGTCGATCAGTTTCGTGATCAT
CTCCGTGGGCGGCATCGCGACGGGCGCGGCGGTGAGCTGGCTGTTCAGCTTCGTGTCGGCGCGCTTCCTGAATCTCACTG
AAGACGGCGATCCGGCGCCCGGTGTCGTGATGACGCTGCTGATTCCGTTCGCCGCCTATCTGATCGCCGAGCGCTTCGAA
TTGTCGGGCATTCTGGCCGCAGTCGCCGCCGGCATGACGATGAACTACGCGACCCTCGCGAATGCCGGGCCGGTGTCCTC
GCGCGTGCGCGCCAACAGCACGTGGACGATGATCGAGTTCGTCTTCAACGGCATGGTGTTCATTCTGCTGGGGCTGCAGT
TTCCGCACATTCTTGGCCGCGCGCTGCTCGATGCACACGAGACGAGCAACGCGCAGGTCGGGCTGCTGATCGGCTATATC
GCGGCAGTGGCTGCTGCCCTCTATGCGATGCGCTTCGTGTGGGTGTGGCTGCTGCGCTGGGTCGCGAGCCGCGGCGCCAC
GAAGCGGGGCATGGCGAATGCGGTGCCGGGCTTGCGCACGGTCGCGGTGACGACGGTGGCCGGCGTGCGCGGAGCCGTGA
CGCTCGCCGGCGTGCTGTCGTTGCCGGAGGTGTTGCCGGATGGCGTCCCGCTGCCGGGCCGCGATCTGGCGATCTTCATT
GCGTCCGGCGTGATCCTGCTCTCGCTGCTGGTGGCGGTGGTGGCGCTGCCGCTGTTGCTGAGCGGCTGGCGGCGCGGCAA
GGATCCACATGCCGCCGAGGAGTTGCTCGCGCGTACGCTGGCCGCGCAAGCCGCGATTCGCGCCGTCGACGAGGTGCACG
ACACCGAGTGCGCGGATCTGGACGAATCCGCTTCGGCGTATGCGGCCGATGTCACCGCGCGCGTGATGGATCTCTATCGG
CGCCGCCTCGCCACGCTCGACGAAGAGCAGGAACCGCGCGAACTGGCGCGCCGCGCCGACGCGCTGGAGTTCAGGATGAA
GCTCGCGGCCATGCGCGCCGAGCGCAAGACGCTGCTCGCGCTGCGCAGCAGCCAGGCTATCAACGACGAGACGTTGAACA
AGCTCATGCGCGAAGTGGATCTGTCGGAGACTGCGCTGACGGCGCGAAGGAAATGA

Upstream 100 bases:

>100_bases
TAAACTGCTGCCTTACACTTCGTCAGCGTCGCGTGGCCATATCGTCGATGCTCACCGAAGGCCACCGCAGCAACGCCGTC
ATATCGCCAGAAATAGACCG

Downstream 100 bases:

>100_bases
CGCGCTGCCGGGTTGCGGTTCCGGCGGCGGGCGCCTGCTGCTTCGAATGAGACATCACGAAAGAAGAGGCCGACGCCGCC
GGTGAACCCGCTGATACCGG

Product: CPA1 family Na(+)/H(+) antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MDIVFTVLILLLAVAASGVVIRILPIALPLPLVQIAIGALLAWPKLGLHVTFDPEIFMMLFIPPLLFADGWRIPKREFFM
ARRSILMLALGLVFVTVLVVGYFVHALVPSISLPVAFALAAVLSPTDAVALSGIVGKGKIPGRLMHILEGEALMNDASGL
VALKFAIAAALTGVFSLRDASISFVIISVGGIATGAAVSWLFSFVSARFLNLTEDGDPAPGVVMTLLIPFAAYLIAERFE
LSGILAAVAAGMTMNYATLANAGPVSSRVRANSTWTMIEFVFNGMVFILLGLQFPHILGRALLDAHETSNAQVGLLIGYI
AAVAAALYAMRFVWVWLLRWVASRGATKRGMANAVPGLRTVAVTTVAGVRGAVTLAGVLSLPEVLPDGVPLPGRDLAIFI
ASGVILLSLLVAVVALPLLLSGWRRGKDPHAAEELLARTLAAQAAIRAVDEVHDTECADLDESASAYAADVTARVMDLYR
RRLATLDEEQEPRELARRADALEFRMKLAAMRAERKTLLALRSSQAINDETLNKLMREVDLSETALTARRK

Sequences:

>Translated_551_residues
MDIVFTVLILLLAVAASGVVIRILPIALPLPLVQIAIGALLAWPKLGLHVTFDPEIFMMLFIPPLLFADGWRIPKREFFM
ARRSILMLALGLVFVTVLVVGYFVHALVPSISLPVAFALAAVLSPTDAVALSGIVGKGKIPGRLMHILEGEALMNDASGL
VALKFAIAAALTGVFSLRDASISFVIISVGGIATGAAVSWLFSFVSARFLNLTEDGDPAPGVVMTLLIPFAAYLIAERFE
LSGILAAVAAGMTMNYATLANAGPVSSRVRANSTWTMIEFVFNGMVFILLGLQFPHILGRALLDAHETSNAQVGLLIGYI
AAVAAALYAMRFVWVWLLRWVASRGATKRGMANAVPGLRTVAVTTVAGVRGAVTLAGVLSLPEVLPDGVPLPGRDLAIFI
ASGVILLSLLVAVVALPLLLSGWRRGKDPHAAEELLARTLAAQAAIRAVDEVHDTECADLDESASAYAADVTARVMDLYR
RRLATLDEEQEPRELARRADALEFRMKLAAMRAERKTLLALRSSQAINDETLNKLMREVDLSETALTARRK
>Mature_551_residues
MDIVFTVLILLLAVAASGVVIRILPIALPLPLVQIAIGALLAWPKLGLHVTFDPEIFMMLFIPPLLFADGWRIPKREFFM
ARRSILMLALGLVFVTVLVVGYFVHALVPSISLPVAFALAAVLSPTDAVALSGIVGKGKIPGRLMHILEGEALMNDASGL
VALKFAIAAALTGVFSLRDASISFVIISVGGIATGAAVSWLFSFVSARFLNLTEDGDPAPGVVMTLLIPFAAYLIAERFE
LSGILAAVAAGMTMNYATLANAGPVSSRVRANSTWTMIEFVFNGMVFILLGLQFPHILGRALLDAHETSNAQVGLLIGYI
AAVAAALYAMRFVWVWLLRWVASRGATKRGMANAVPGLRTVAVTTVAGVRGAVTLAGVLSLPEVLPDGVPLPGRDLAIFI
ASGVILLSLLVAVVALPLLLSGWRRGKDPHAAEELLARTLAAQAAIRAVDEVHDTECADLDESASAYAADVTARVMDLYR
RRLATLDEEQEPRELARRADALEFRMKLAAMRAERKTLLALRSSQAINDETLNKLMREVDLSETALTARRK

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI5454070, Length=301, Percent_Identity=24.5847176079734, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI41872703, Length=323, Percent_Identity=25.077399380805, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI110227626, Length=269, Percent_Identity=25.2788104089219, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI294997330, Length=269, Percent_Identity=25.2788104089219, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI27734935, Length=265, Percent_Identity=26.4150943396226, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI14211919, Length=257, Percent_Identity=26.0700389105058, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI15529998, Length=559, Percent_Identity=23.4347048300537, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI148727259, Length=307, Percent_Identity=24.4299674267101, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1790501, Length=554, Percent_Identity=48.9169675090253, Blast_Score=474, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI71993590, Length=323, Percent_Identity=25.077399380805, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71993582, Length=323, Percent_Identity=25.077399380805, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71980847, Length=260, Percent_Identity=27.3076923076923, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25150332, Length=370, Percent_Identity=22.4324324324324, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71987545, Length=491, Percent_Identity=23.8289205702648, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71987559, Length=491, Percent_Identity=23.8289205702648, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71992107, Length=258, Percent_Identity=22.4806201550388, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71992101, Length=258, Percent_Identity=22.4806201550388, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71999819, Length=406, Percent_Identity=23.6453201970443, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71999817, Length=406, Percent_Identity=23.6453201970443, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71999821, Length=378, Percent_Identity=24.3386243386243, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320663, Length=351, Percent_Identity=24.7863247863248, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221473215, Length=273, Percent_Identity=24.5421245421245, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221473212, Length=467, Percent_Identity=23.1263383297645, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281364513, Length=273, Percent_Identity=24.5421245421245, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221473222, Length=273, Percent_Identity=24.5421245421245, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281360447, Length=318, Percent_Identity=23.8993710691824, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 58954; Mature: 58954

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIVFTVLILLLAVAASGVVIRILPIALPLPLVQIAIGALLAWPKLGLHVTFDPEIFMML
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHH
FIPPLLFADGWRIPKREFFMARRSILMLALGLVFVTVLVVGYFVHALVPSISLPVAFALA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AVLSPTDAVALSGIVGKGKIPGRLMHILEGEALMNDASGLVALKFAIAAALTGVFSLRDA
HHHCCCHHHHHHCCCCCCCCCHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
SISFVIISVGGIATGAAVSWLFSFVSARFLNLTEDGDPAPGVVMTLLIPFAAYLIAERFE
CEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LSGILAAVAAGMTMNYATLANAGPVSSRVRANSTWTMIEFVFNGMVFILLGLQFPHILGR
HHHHHHHHHHCCHHCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLDAHETSNAQVGLLIGYIAAVAAALYAMRFVWVWLLRWVASRGATKRGMANAVPGLRT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHH
VAVTTVAGVRGAVTLAGVLSLPEVLPDGVPLPGRDLAIFIASGVILLSLLVAVVALPLLL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SGWRRGKDPHAAEELLARTLAAQAAIRAVDEVHDTECADLDESASAYAADVTARVMDLYR
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RRLATLDEEQEPRELARRADALEFRMKLAAMRAERKTLLALRSSQAINDETLNKLMREVD
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
LSETALTARRK
CHHHHHHHCCC
>Mature Secondary Structure
MDIVFTVLILLLAVAASGVVIRILPIALPLPLVQIAIGALLAWPKLGLHVTFDPEIFMML
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHH
FIPPLLFADGWRIPKREFFMARRSILMLALGLVFVTVLVVGYFVHALVPSISLPVAFALA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AVLSPTDAVALSGIVGKGKIPGRLMHILEGEALMNDASGLVALKFAIAAALTGVFSLRDA
HHHCCCHHHHHHCCCCCCCCCHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
SISFVIISVGGIATGAAVSWLFSFVSARFLNLTEDGDPAPGVVMTLLIPFAAYLIAERFE
CEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LSGILAAVAAGMTMNYATLANAGPVSSRVRANSTWTMIEFVFNGMVFILLGLQFPHILGR
HHHHHHHHHHCCHHCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLDAHETSNAQVGLLIGYIAAVAAALYAMRFVWVWLLRWVASRGATKRGMANAVPGLRT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHH
VAVTTVAGVRGAVTLAGVLSLPEVLPDGVPLPGRDLAIFIASGVILLSLLVAVVALPLLL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SGWRRGKDPHAAEELLARTLAAQAAIRAVDEVHDTECADLDESASAYAADVTARVMDLYR
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RRLATLDEEQEPRELARRADALEFRMKLAAMRAERKTLLALRSSQAINDETLNKLMREVD
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
LSETALTARRK
CHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]