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The map label for this gene is htpX [H]

Identifier: 91781433

GI number: 91781433

Start: 64646

End: 65536

Strand: Direct

Name: htpX [H]

Synonym: Bxe_A4413

Alternate gene names: 91781433

Gene position: 64646-65536 (Clockwise)

Preceding gene: 91781432

Following gene: 91781434

Centisome position: 1.32

GC content: 63.19

Gene sequence:

>891_bases
ATGAACCCCGCGTTAGGGCAAGGAGTTGCAGACATGTTCAATTGGGTCAAAACCGCGATGTTGATGGCCGCGATCACGGC
CCTTTTCATCGTGATCGGCGGGATGATCGGCGGGTCGCGCGGCATGACGATCGCGCTCGTGATCGCCCTTGGAATGAATT
TCTTTTCGTACTGGTTCTCGGACAAGATGGTGCTGCGCATGTACAACGCGCAGGAGGTCGACGAAACCAGCGCGCCGCAG
TTCTATCGCATGGTGCGCGAGCTTTCCACGCGCGCCGGCCTGCCCATGCCGCGCGTGTACCTGATCAATGAAGATGCGCC
GAACGCGTTCGCCACCGGCCGCAATCCGGAGCATGCGGCGGTCGCCGCCACCACCGGCATTCTGCGTGTGCTGTCCGAGC
GCGAAATGCGCGGCGTGATGGCGCATGAACTCGCGCACGTGAAGCATCGCGACATTCTGATTTCAACCGTCTCGGCCACG
ATGGCCGGCGCCATTTCCGCGCTGGCGAACTTCGCGATGTTCTTCGGCGGGCGCGACGAAAACGGTCGGCCCACGAACCC
GATCGCGAGCATTGCGGTCGCGCTGCTGGCGCCGATCGCCGGTGCGCTGATTCAGATGGCGATTTCGCGGGCACGTGAAT
TCGAAGCCGACCGCGGCGGCGCACAGATTTCCGGCGACCCGCAGGCGCTCGCTTCGGCGCTCGACAAGATCCACCGTTAC
GCGAGCGGGATTCCGTTTCCCACCGCCGAGCAGCATCCGGCCACCGCGCAAATGATGATCATGAATCCGTTGGCGGGCGG
CGGCATCGCGAATCTGTTCTCCACGCACCCGGCTACCGAGGAACGCATCGCACGTTTGATGGAAATGGCGCGCACGGGGC
GCTTCGAATAA

Upstream 100 bases:

>100_bases
GCATCAAGCTAGCCACCGCGTCGAGATGATTGAATTTTCCTCGCGCGCCCATATCTAACGTTTCGCTTACAATCAGGCGC
CGCGATCACGCGGTGCAGAT

Downstream 100 bases:

>100_bases
CGCCGCGACAACACCGCGCGCGGCGTTCAGGAAGGCGAGTCCGAGGGCTCGCCTTTTTATGCGGAACGCAAAGGGAAAAC
GAACGAGCGGCGGCGCTGCT

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNPALGQGVADMFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALVIALGMNFFSYWFSDKMVLRMYNAQEVDETSAPQ
FYRMVRELSTRAGLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTVSAT
MAGAISALANFAMFFGGRDENGRPTNPIASIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRY
ASGIPFPTAEQHPATAQMMIMNPLAGGGIANLFSTHPATEERIARLMEMARTGRFE

Sequences:

>Translated_296_residues
MNPALGQGVADMFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALVIALGMNFFSYWFSDKMVLRMYNAQEVDETSAPQ
FYRMVRELSTRAGLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTVSAT
MAGAISALANFAMFFGGRDENGRPTNPIASIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRY
ASGIPFPTAEQHPATAQMMIMNPLAGGGIANLFSTHPATEERIARLMEMARTGRFE
>Mature_296_residues
MNPALGQGVADMFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALVIALGMNFFSYWFSDKMVLRMYNAQEVDETSAPQ
FYRMVRELSTRAGLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTVSAT
MAGAISALANFAMFFGGRDENGRPTNPIASIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRY
ASGIPFPTAEQHPATAQMMIMNPLAGGGIANLFSTHPATEERIARLMEMARTGRFE

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=269, Percent_Identity=31.9702602230483, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 31856; Mature: 31856

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPALGQGVADMFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALVIALGMNFFSYWFS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
DKMVLRMYNAQEVDETSAPQFYRMVRELSTRAGLPMPRVYLINEDAPNAFATGRNPEHAA
CHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHH
VAATTGILRVLSEREMRGVMAHELAHVKHRDILISTVSATMAGAISALANFAMFFGGRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NGRPTNPIASIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
ASGIPFPTAEQHPATAQMMIMNPLAGGGIANLFSTHPATEERIARLMEMARTGRFE
HCCCCCCCCCCCCCHHHHHEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNPALGQGVADMFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALVIALGMNFFSYWFS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
DKMVLRMYNAQEVDETSAPQFYRMVRELSTRAGLPMPRVYLINEDAPNAFATGRNPEHAA
CHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHH
VAATTGILRVLSEREMRGVMAHELAHVKHRDILISTVSATMAGAISALANFAMFFGGRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NGRPTNPIASIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
ASGIPFPTAEQHPATAQMMIMNPLAGGGIANLFSTHPATEERIARLMEMARTGRFE
HCCCCCCCCCCCCCHHHHHEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA