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The map label for this gene is garD [H]

Identifier: 91781399

GI number: 91781399

Start: 19242

End: 20768

Strand: Reverse

Name: garD [H]

Synonym: Bxe_A4448

Alternate gene names: 91781399

Gene position: 20768-19242 (Counterclockwise)

Preceding gene: 91781401

Following gene: 91781398

Centisome position: 0.42

GC content: 65.09

Gene sequence:

>1527_bases
ATGAACACGCTTTCATCCGTGATCCGGCTTCACGACGACGATGACGTCGCGATCGCCCGCAATGCCCTGACGGCCGGCAC
CGTACTCACTGAGCTGGATGGCCTGACGGTCCGCGCGGACATTCCCGCCGCCCACAAGATCGCGCTGCGCCCGATCGAAG
CCGGCAGCATCGTGCGCCGCTACGGCCAGACCATCGGGTTCGCCACGCAGCGCATCGAGCCGGGCGAGCACGTGCACGTC
CACAATGTGTCGATGGGCGACTTCGAGCGCGACTATGCGTTCGGCGCGGACGTGAGGCCGGTCGAAGCCGCGAGCACGCC
GGTGACTTTCCAGGGCTTTCGCCGCGCCGACGGCCAGGTGGCGACGCGCAACTACATTGGTGTGATCAGCACCGTGAACT
GCTCGGCGACGGTGAGCAAGATGGTCGCCCAGCACTTCAGCGCGCCGGGCCGGCTCGACGCGTATCCGAACGTGGACGGC
GTCGTGCCGATCACGCACAGCTTCGGCTGCTGCATCGATCACAACGGCGAAGGCATTCAGCAACTGCGTCGCACCATCAA
CGGCTTCGTGAAGCATCCGAACTTTGCCGGCGTGCTGGTGATCGGTCTGGGCTGCGAAGCGAACCAGATGGGCGCGATGT
TCATGACCGGCGGCATCGAGACCGGTCCGATGATGGTGCCGCTCGTCATGCAGGAGCAAGGCGGGACGCAGAAAACCGTC
GACGCGGCGATCAAGGCCATCGACCAGATGCTGCCCGTCGCCAATCAGGCGCAGCGCGAGCCCTTGCCGATCTCGCATCT
GAATATCGCGCTGCAGTGCGGCGGCTCCGACGGCTACTCGGGGATCACCGCCAATCCCGCGCTCGGCGCGGCTGTCGACC
TGCTGGTCGCACACGGCGGGACCGCGATTCTGTCGGAGACGCCCGAAATCTATGGCGCCGAGCATCTGCTGACGCGCCGT
GCGATTTCGCGCGACGTGGGCGAGAAGATCGTCGAGCGCATTCACTGGTGGGAAGCGTATGCCGAGCGCGAAAAGGGCAG
CATCGACAACAATCCGACGCCGGGCAACAAAGCCGGCGGCCTGACGACGATTCTCGAAAAGTCGCTCGGCGCGGTGGCAA
AGAGCGGTTCGACGCCGCTGATGGGCGTCTATCGCTACGCGGAACCGGTCGATACGCACGGCCTCGTGTTCATGGATGCG
CCCGGTTATGACCCGATGGGCGCAACCGGGCAGATCGCGAGCGGCGCCAACCTCGTGGTGTTCACGACCGGCCGCGGCTC
GTGCTTCGGCGCGAAGCCGGCGCCGTCCATCAAGGTCGCGACGAATACGCCGATGTTCAACCGGATGCGCGACGACATGG
ACATCAACTGTGGCGACATCATGGAAGGGCACGCGACGGTGCGGCAGAAAGGCGAGGAGATTTTCCGCGCGATCGTCGAA
GTTGCGTCCGGCGTAAAGAGCAAAAGCGAAGCGCTCGGCGTCGGCAACGAGGAATTCGTGCCGTGGATGATCGGCGCCCA
GATGTGA

Upstream 100 bases:

>100_bases
AGTAGTCAGACCAATTTGTCCGGGTGGTTTCGATTATCCATGATGCGATCAAGCGGCGCACGACGCGGCGTCGTCGATCC
CCCACAATCTGGAGACGAAC

Downstream 100 bases:

>100_bases
GGCGGGCTCCGTCCTGATGCGGGCGCGTCGACCGGCTGGATAAATCCCAAACTCCGCTCGCCGCCAGTCACATTGGAACT
GGATGAACAGTTGCGATAGA

Product: Altronate dehydratase

Products: NA

Alternate protein names: GalcD [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MNTLSSVIRLHDDDDVAIARNALTAGTVLTELDGLTVRADIPAAHKIALRPIEAGSIVRRYGQTIGFATQRIEPGEHVHV
HNVSMGDFERDYAFGADVRPVEAASTPVTFQGFRRADGQVATRNYIGVISTVNCSATVSKMVAQHFSAPGRLDAYPNVDG
VVPITHSFGCCIDHNGEGIQQLRRTINGFVKHPNFAGVLVIGLGCEANQMGAMFMTGGIETGPMMVPLVMQEQGGTQKTV
DAAIKAIDQMLPVANQAQREPLPISHLNIALQCGGSDGYSGITANPALGAAVDLLVAHGGTAILSETPEIYGAEHLLTRR
AISRDVGEKIVERIHWWEAYAEREKGSIDNNPTPGNKAGGLTTILEKSLGAVAKSGSTPLMGVYRYAEPVDTHGLVFMDA
PGYDPMGATGQIASGANLVVFTTGRGSCFGAKPAPSIKVATNTPMFNRMRDDMDINCGDIMEGHATVRQKGEEIFRAIVE
VASGVKSKSEALGVGNEEFVPWMIGAQM

Sequences:

>Translated_508_residues
MNTLSSVIRLHDDDDVAIARNALTAGTVLTELDGLTVRADIPAAHKIALRPIEAGSIVRRYGQTIGFATQRIEPGEHVHV
HNVSMGDFERDYAFGADVRPVEAASTPVTFQGFRRADGQVATRNYIGVISTVNCSATVSKMVAQHFSAPGRLDAYPNVDG
VVPITHSFGCCIDHNGEGIQQLRRTINGFVKHPNFAGVLVIGLGCEANQMGAMFMTGGIETGPMMVPLVMQEQGGTQKTV
DAAIKAIDQMLPVANQAQREPLPISHLNIALQCGGSDGYSGITANPALGAAVDLLVAHGGTAILSETPEIYGAEHLLTRR
AISRDVGEKIVERIHWWEAYAEREKGSIDNNPTPGNKAGGLTTILEKSLGAVAKSGSTPLMGVYRYAEPVDTHGLVFMDA
PGYDPMGATGQIASGANLVVFTTGRGSCFGAKPAPSIKVATNTPMFNRMRDDMDINCGDIMEGHATVRQKGEEIFRAIVE
VASGVKSKSEALGVGNEEFVPWMIGAQM
>Mature_508_residues
MNTLSSVIRLHDDDDVAIARNALTAGTVLTELDGLTVRADIPAAHKIALRPIEAGSIVRRYGQTIGFATQRIEPGEHVHV
HNVSMGDFERDYAFGADVRPVEAASTPVTFQGFRRADGQVATRNYIGVISTVNCSATVSKMVAQHFSAPGRLDAYPNVDG
VVPITHSFGCCIDHNGEGIQQLRRTINGFVKHPNFAGVLVIGLGCEANQMGAMFMTGGIETGPMMVPLVMQEQGGTQKTV
DAAIKAIDQMLPVANQAQREPLPISHLNIALQCGGSDGYSGITANPALGAAVDLLVAHGGTAILSETPEIYGAEHLLTRR
AISRDVGEKIVERIHWWEAYAEREKGSIDNNPTPGNKAGGLTTILEKSLGAVAKSGSTPLMGVYRYAEPVDTHGLVFMDA
PGYDPMGATGQIASGANLVVFTTGRGSCFGAKPAPSIKVATNTPMFNRMRDDMDINCGDIMEGHATVRQKGEEIFRAIVE
VASGVKSKSEALGVGNEEFVPWMIGAQM

Specific function: D-galactarate metabolism; first step. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789516, Length=505, Percent_Identity=38.6138613861386, Blast_Score=318, Evalue=6e-88,
Organism=Escherichia coli, GI1789475, Length=486, Percent_Identity=36.2139917695473, Blast_Score=295, Evalue=4e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR017654
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.42 [H]

Molecular weight: Translated: 53990; Mature: 53990

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLSSVIRLHDDDDVAIARNALTAGTVLTELDGLTVRADIPAAHKIALRPIEAGSIVRR
CCCHHHHHEECCCCCEEHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCHHHHHHH
YGQTIGFATQRIEPGEHVHVHNVSMGDFERDYAFGADVRPVEAASTPVTFQGFRRADGQV
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHCCCCCE
ATRNYIGVISTVNCSATVSKMVAQHFSAPGRLDAYPNVDGVVPITHSFGCCIDHNGEGIQ
EECCEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEECCCCHHHH
QLRRTINGFVKHPNFAGVLVIGLGCEANQMGAMFMTGGIETGPMMVPLVMQEQGGTQKTV
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCEEEEEEEECCCCCHHHH
DAAIKAIDQMLPVANQAQREPLPISHLNIALQCGGSDGYSGITANPALGAAVDLLVAHGG
HHHHHHHHHHHCCHHHHHCCCCCCCEEEEEEEECCCCCCCCEECCCCHHHHHHHHHHCCC
TAILSETPEIYGAEHLLTRRAISRDVGEKIVERIHWWEAYAEREKGSIDNNPTPGNKAGG
EEEECCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LTTILEKSLGAVAKSGSTPLMGVYRYAEPVDTHGLVFMDAPGYDPMGATGQIASGANLVV
HHHHHHHHHHHHHCCCCCCCEEHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEE
FTTGRGSCFGAKPAPSIKVATNTPMFNRMRDDMDINCGDIMEGHATVRQKGEEIFRAIVE
EECCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
VASGVKSKSEALGVGNEEFVPWMIGAQM
HHHCCCCHHHHCCCCCCCCCCEECCCCC
>Mature Secondary Structure
MNTLSSVIRLHDDDDVAIARNALTAGTVLTELDGLTVRADIPAAHKIALRPIEAGSIVRR
CCCHHHHHEECCCCCEEHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCHHHHHHH
YGQTIGFATQRIEPGEHVHVHNVSMGDFERDYAFGADVRPVEAASTPVTFQGFRRADGQV
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHCCCCCE
ATRNYIGVISTVNCSATVSKMVAQHFSAPGRLDAYPNVDGVVPITHSFGCCIDHNGEGIQ
EECCEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEECCCCHHHH
QLRRTINGFVKHPNFAGVLVIGLGCEANQMGAMFMTGGIETGPMMVPLVMQEQGGTQKTV
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCEEEEEEEECCCCCHHHH
DAAIKAIDQMLPVANQAQREPLPISHLNIALQCGGSDGYSGITANPALGAAVDLLVAHGG
HHHHHHHHHHHCCHHHHHCCCCCCCEEEEEEEECCCCCCCCEECCCCHHHHHHHHHHCCC
TAILSETPEIYGAEHLLTRRAISRDVGEKIVERIHWWEAYAEREKGSIDNNPTPGNKAGG
EEEECCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LTTILEKSLGAVAKSGSTPLMGVYRYAEPVDTHGLVFMDAPGYDPMGATGQIASGANLVV
HHHHHHHHHHHHHCCCCCCCEEHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEE
FTTGRGSCFGAKPAPSIKVATNTPMFNRMRDDMDINCGDIMEGHATVRQKGEEIFRAIVE
EECCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
VASGVKSKSEALGVGNEEFVPWMIGAQM
HHHCCCCHHHHCCCCCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]