Click here to switch to the map view.

The map label for this gene is tctD [H]

Identifier: 91790516

GI number: 91790516

Start: 4974627

End: 4975298

Strand: Direct

Name: tctD [H]

Synonym: Bpro_4687

Alternate gene names: 91790516

Gene position: 4974627-4975298 (Clockwise)

Preceding gene: 91790515

Following gene: 91790517

Centisome position: 95.66

GC content: 65.62

Gene sequence:

>672_bases
ATGCGTATTCTGATTGCCGAAGACGACCAGGTTCTGGCCGATGGCCTGTTGCGCACCCTGCGCGCGTCAGGCGCCGCGGC
GGACCATGTAGCGAGCGGCACCGAGGCCGATGCCGCATTGCTCACCAACACGGAATTTGATTTGCTGATTCTCGACCTGG
GCCTGCCGCGCATGCACGGGCTGGAAGTGCTGAAAAGGCTGCGCGCGCGCGGCTCGGCACTGCCGGTGCTGATACTCACC
GCGGCCGACAGCGTGGAAGAACGCGTCAAGGGCCTGGACTACGGCGCGGACGACTACATGGCCAAACCGTTCTCGCTGCA
GGAGCTCGAAGCGCGCGTGCGCGCCCTGATACGCCGCGGCATGGGCGGCGCCAGCAGCACCATCAAGCACGGGCCGCTGG
TCTATGACCAGGCCGGGCGGGTCGCCACCATTGACGGCCAGATGCTGGAGCTGTCGGCGCGCGAGCTGGGCCTGCTCGAA
GTGCTGCTGCAGCGCGCCGGCCGCCTGGTGAGCAAGGACCAGCTGGTCGAGCGCCTGTGCGAGTGGGGCGAGGAAGTCAG
CAACAACGCCATCGAGGTCTATATCCACCGTCTGCGCAAGAAGATTGAAAAGGGGCCGATACGCATTGCGACGGTGCGCG
GGCTGGGGTACTGCCTTGAAAAAATCCCGTGA

Upstream 100 bases:

>100_bases
TTTCGTAAGCAAACCCCTGACCGCAAAAGCCTAGAATTTGATAGAGAACAAAAAAATACCGTCTGCTGGCCCTGCCGCGG
GCCAATATCTGGAGACAGCC

Downstream 100 bases:

>100_bases
ATGTAGCCCCCACGCTTGCCACTTCGTGTGCTGCGCTGCCCCCCGAGGGGGCGCTGCGCCTGCGGCCCGGCAAAGCCGGT
TCCGCGGCCCTGACTTGCAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MRILIAEDDQVLADGLLRTLRASGAAADHVASGTEADAALLTNTEFDLLILDLGLPRMHGLEVLKRLRARGSALPVLILT
AADSVEERVKGLDYGADDYMAKPFSLQELEARVRALIRRGMGGASSTIKHGPLVYDQAGRVATIDGQMLELSARELGLLE
VLLQRAGRLVSKDQLVERLCEWGEEVSNNAIEVYIHRLRKKIEKGPIRIATVRGLGYCLEKIP

Sequences:

>Translated_223_residues
MRILIAEDDQVLADGLLRTLRASGAAADHVASGTEADAALLTNTEFDLLILDLGLPRMHGLEVLKRLRARGSALPVLILT
AADSVEERVKGLDYGADDYMAKPFSLQELEARVRALIRRGMGGASSTIKHGPLVYDQAGRVATIDGQMLELSARELGLLE
VLLQRAGRLVSKDQLVERLCEWGEEVSNNAIEVYIHRLRKKIEKGPIRIATVRGLGYCLEKIP
>Mature_223_residues
MRILIAEDDQVLADGLLRTLRASGAAADHVASGTEADAALLTNTEFDLLILDLGLPRMHGLEVLKRLRARGSALPVLILT
AADSVEERVKGLDYGADDYMAKPFSLQELEARVRALIRRGMGGASSTIKHGPLVYDQAGRVATIDGQMLELSARELGLLE
VLLQRAGRLVSKDQLVERLCEWGEEVSNNAIEVYIHRLRKKIEKGPIRIATVRGLGYCLEKIP

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=45.2054794520548, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=42.9223744292237, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=38.7387387387387, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=36.7713004484305, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=36.1990950226244, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=36.6071428571429, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=34.7826086956522, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=33.4821428571429, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=33.9285714285714, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=32.8888888888889, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI2367329, Length=176, Percent_Identity=36.3636363636364, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=29.0748898678414, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.0748898678414, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI145693140, Length=188, Percent_Identity=31.3829787234043, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787487, Length=121, Percent_Identity=35.5371900826446, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1788550, Length=151, Percent_Identity=31.1258278145695, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=34.2342342342342, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=109, Percent_Identity=36.697247706422, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1788713, Length=116, Percent_Identity=34.4827586206897, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24418; Mature: 24418

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIAEDDQVLADGLLRTLRASGAAADHVASGTEADAALLTNTEFDLLILDLGLPRMHG
CEEEEECCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHEEECCCCEEEEEECCCCCHHH
LEVLKRLRARGSALPVLILTAADSVEERVKGLDYGADDYMAKPFSLQELEARVRALIRRG
HHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHC
MGGASSTIKHGPLVYDQAGRVATIDGQMLELSARELGLLEVLLQRAGRLVSKDQLVERLC
CCCCCCCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EWGEEVSNNAIEVYIHRLRKKIEKGPIRIATVRGLGYCLEKIP
HHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHCC
>Mature Secondary Structure
MRILIAEDDQVLADGLLRTLRASGAAADHVASGTEADAALLTNTEFDLLILDLGLPRMHG
CEEEEECCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHEEECCCCEEEEEECCCCCHHH
LEVLKRLRARGSALPVLILTAADSVEERVKGLDYGADDYMAKPFSLQELEARVRALIRRG
HHHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHC
MGGASSTIKHGPLVYDQAGRVATIDGQMLELSARELGLLEVLLQRAGRLVSKDQLVERLC
CCCCCCCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EWGEEVSNNAIEVYIHRLRKKIEKGPIRIATVRGLGYCLEKIP
HHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]