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The map label for this gene is gpwA [H]

Identifier: 91790488

GI number: 91790488

Start: 4949961

End: 4950587

Strand: Direct

Name: gpwA [H]

Synonym: Bpro_4659

Alternate gene names: 91790488

Gene position: 4949961-4950587 (Clockwise)

Preceding gene: 91790485

Following gene: 91790489

Centisome position: 95.19

GC content: 60.13

Gene sequence:

>627_bases
ATGCACAACCTGTGGACTCCCCTCTCCCGGCCACTGCCGCGAATTGCCCTGCTGACCGGCCTTGCGCTCTCGACAATCGC
CGCGAACTCGGCAGCGCCGGCTCCGTCGGCATCGGTTGCCGGATCCGTTGCCGCAGACGCGTCGGCCTGCCCAGGCCTGT
TGCAGCACAACTTCCTGCGACTGCAGGATGAAAAACCGCAATCGCTTTGCCAGTACCAGGGCAAGGTCGTGGTGGCGGTC
AATACCGCCAGCTTTTGCGGTTTTACGTCCCAATACCAGGGCCTGGAAGAGCTTTATGCGAAATACAAGGACCGTGGGCT
GGTGGTCCTGGGCTTTCCCTCCAACGACTTTTCGCAGGAAACCGGCAGCAACAAGGAGATTGCCGACTTTTGCGAAAACA
CCTTCGGCGTGAAATTCCCGATGTTCGCCAAAACCAGCGTCAGCGGCAAGGACGCCAACCCCCTTTTCAGGCAGCTGGCC
GCCAAAACCGGCACCACACCACGCTGGAACTTTTACAAGTATGTGATTGCGCGGGACGGCACCAGTGTCGCCAGCTTCAA
CTCCCTGACCGCCCCAGGAAGCCGCCAGTTCGTCAAAGAAATCGAAAAGCAGCTGGCCCGCCCCTGA

Upstream 100 bases:

>100_bases
CCGCGTACCCCGACGGCATGTGCCAGGTGCGAGCCGTGCTGGATGGCTACCGCGAACGCCAATAGCGCCATAATTGTTTG
ACTCCAAAGGAATTTCTGGC

Downstream 100 bases:

>100_bases
GCCCTTGGGTCGGTCAACCCTGACATAAAAATTACCATCTGGTCTCAATTTTGACTATGTGGTAATTTAACCCTTATGAT
GGGGGAATGCGCAGACTTTG

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MHNLWTPLSRPLPRIALLTGLALSTIAANSAAPAPSASVAGSVAADASACPGLLQHNFLRLQDEKPQSLCQYQGKVVVAV
NTASFCGFTSQYQGLEELYAKYKDRGLVVLGFPSNDFSQETGSNKEIADFCENTFGVKFPMFAKTSVSGKDANPLFRQLA
AKTGTTPRWNFYKYVIARDGTSVASFNSLTAPGSRQFVKEIEKQLARP

Sequences:

>Translated_208_residues
MHNLWTPLSRPLPRIALLTGLALSTIAANSAAPAPSASVAGSVAADASACPGLLQHNFLRLQDEKPQSLCQYQGKVVVAV
NTASFCGFTSQYQGLEELYAKYKDRGLVVLGFPSNDFSQETGSNKEIADFCENTFGVKFPMFAKTSVSGKDANPLFRQLA
AKTGTTPRWNFYKYVIARDGTSVASFNSLTAPGSRQFVKEIEKQLARP
>Mature_208_residues
MHNLWTPLSRPLPRIALLTGLALSTIAANSAAPAPSASVAGSVAADASACPGLLQHNFLRLQDEKPQSLCQYQGKVVVAV
NTASFCGFTSQYQGLEELYAKYKDRGLVVLGFPSNDFSQETGSNKEIADFCENTFGVKFPMFAKTSVSGKDANPLFRQLA
AKTGTTPRWNFYKYVIARDGTSVASFNSLTAPGSRQFVKEIEKQLARP

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=122, Percent_Identity=45.9016393442623, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI192455698, Length=118, Percent_Identity=39.8305084745763, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI75709200, Length=170, Percent_Identity=33.5294117647059, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI90903240, Length=133, Percent_Identity=37.593984962406, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI90903238, Length=115, Percent_Identity=40, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI4557629, Length=146, Percent_Identity=34.9315068493151, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI41406084, Length=153, Percent_Identity=32.6797385620915, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI6006001, Length=164, Percent_Identity=29.8780487804878, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1788003, Length=170, Percent_Identity=35.8823529411765, Blast_Score=110, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17535473, Length=143, Percent_Identity=38.4615384615385, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17506887, Length=146, Percent_Identity=36.986301369863, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71993584, Length=151, Percent_Identity=30.4635761589404, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193210707, Length=148, Percent_Identity=38.5135135135135, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17550320, Length=168, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193209493, Length=168, Percent_Identity=27.9761904761905, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=157, Percent_Identity=42.0382165605096, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322228, Length=149, Percent_Identity=41.6107382550336, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322826, Length=126, Percent_Identity=42.0634920634921, Blast_Score=107, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24656772, Length=145, Percent_Identity=37.2413793103448, Blast_Score=90, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24656777, Length=145, Percent_Identity=37.2413793103448, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24656767, Length=145, Percent_Identity=37.2413793103448, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI85726443, Length=145, Percent_Identity=33.1034482758621, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 22490; Mature: 22490

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNLWTPLSRPLPRIALLTGLALSTIAANSAAPAPSASVAGSVAADASACPGLLQHNFLR
CCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHCCCCCCCHHHHHCCEE
LQDEKPQSLCQYQGKVVVAVNTASFCGFTSQYQGLEELYAKYKDRGLVVLGFPSNDFSQE
ECCCCHHHHHHHCCCEEEEEECHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
TGSNKEIADFCENTFGVKFPMFAKTSVSGKDANPLFRQLAAKTGTTPRWNFYKYVIARDG
CCCCCHHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEECC
TSVASFNSLTAPGSRQFVKEIEKQLARP
CCHHCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHNLWTPLSRPLPRIALLTGLALSTIAANSAAPAPSASVAGSVAADASACPGLLQHNFLR
CCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHCCCCCCCHHHHHCCEE
LQDEKPQSLCQYQGKVVVAVNTASFCGFTSQYQGLEELYAKYKDRGLVVLGFPSNDFSQE
ECCCCHHHHHHHCCCEEEEEECHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
TGSNKEIADFCENTFGVKFPMFAKTSVSGKDANPLFRQLAAKTGTTPRWNFYKYVIARDG
CCCCCHHHHHHHHHCCCCCCCEECCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEECC
TSVASFNSLTAPGSRQFVKEIEKQLARP
CCHHCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA