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The map label for this gene is ttdR [H]

Identifier: 91790379

GI number: 91790379

Start: 4810990

End: 4812048

Strand: Direct

Name: ttdR [H]

Synonym: Bpro_4548

Alternate gene names: 91790379

Gene position: 4810990-4812048 (Clockwise)

Preceding gene: 91790371

Following gene: 91790380

Centisome position: 92.51

GC content: 68.37

Gene sequence:

>1059_bases
ATGTCGTCAGACCAGCTCTCCCCGCTTGTGGCCGACCTTCACCTCCTGACGGTCCTAGCGGCCACCCGCAGCTTCACCGA
GGCGGCACGCCGCCTGGGCGTCTCCAAGGCCTCGGCCAGCACGCGCATCAGCGAGCTGGAGCGCGCCGCCGGCGTTTCGC
TGGTACGCCGGACCACGCGCTCCGTCGGCCTGACCGAGGCGGGCCAGCAGCTGGTCAATGAGATGCAGCCGGCATTCAAC
CGGATCAGCGAGAGCTACACCGCGGTCCGGGACCTCGTCGGCACGCCGCGCGGCCTGATCCGGGTCACCGCGCCGGTGGC
ACTGGGCCGCCAGCACCTGGCACCCTGCGTAGCCGCCTTCCTGAAGCGCTTTCCCGATATCCACATCGAGCTGGAACTGA
CCGACCGCTTCGTCAACCTGGCCAACGAAGGCTTTGACCTGGCCATCCGGCACACCAACACGCCGCCCGAGACGCATGTG
GCCTGGGTGCTGTGCGAAACCCGTTCCTTCCTGCTCGCCAGCCCCGACTACCTGCAGCGCCGGGGCACGCCGTCGCACCC
GTCCGAGCTGACCTCGCACGACTGCCTGCTGTACCTGGGCGGCAGCCATGCCGGCAGCTGGACGTTTGTGCGCAACAGCA
AACGCAAATCGGGCGAACGGGTGGGCGTGACCATCACCGGCACGCTCAAGGCGAACAACAGTGAAGTGCTGCGGGACGCC
CTGCTGGCAGGCCTGGGCATAGGCCTGCTGCCCGACTTCAGCCTGCCGGAAGGATGTGCCCCCACGCTTTTCACTTCGTG
TAATACGCTGCCCCCCGAGGGGGCTGCGCTTGCTCGGGGCGGCCCAGCGCGGCGCGCGGCCCGCGAAAAACACCCACCGC
TGGTGCAGGTGCTGCCTGACTGGCAGGCGCAGGGATTCTTTGGCGAACGCATTTATGCCCTGCGGCCCTGGTCGCCGCAG
GTGCCGAAGGCCGTCCAGTGCTTTGTCGAACACCTGCGCCAGAGTTTTGCCCAGGGGTTTGCCGGCGTGGCGGGTGGCCA
GCCTCCGGCCAGAAGCTGA

Upstream 100 bases:

>100_bases
CTTGAACCAAGTCTAAGACTCTCCGCCCAATTTGATAATGCCCTGTTTACTGATTACATTGTTCATATTCCTGAACAATG
CCAGATACTGGAGCCTCGCC

Downstream 100 bases:

>100_bases
TCCGGAGCAGCTTGCCGGCCAGGGGTTCACCGCGGCGGGACGGGAACACGGGGGGGGGGGGTACGGGCGACACGGATAAT
CACCCCATGAACAAACGATG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSSDQLSPLVADLHLLTVLAATRSFTEAARRLGVSKASASTRISELERAAGVSLVRRTTRSVGLTEAGQQLVNEMQPAFN
RISESYTAVRDLVGTPRGLIRVTAPVALGRQHLAPCVAAFLKRFPDIHIELELTDRFVNLANEGFDLAIRHTNTPPETHV
AWVLCETRSFLLASPDYLQRRGTPSHPSELTSHDCLLYLGGSHAGSWTFVRNSKRKSGERVGVTITGTLKANNSEVLRDA
LLAGLGIGLLPDFSLPEGCAPTLFTSCNTLPPEGAALARGGPARRAAREKHPPLVQVLPDWQAQGFFGERIYALRPWSPQ
VPKAVQCFVEHLRQSFAQGFAGVAGGQPPARS

Sequences:

>Translated_352_residues
MSSDQLSPLVADLHLLTVLAATRSFTEAARRLGVSKASASTRISELERAAGVSLVRRTTRSVGLTEAGQQLVNEMQPAFN
RISESYTAVRDLVGTPRGLIRVTAPVALGRQHLAPCVAAFLKRFPDIHIELELTDRFVNLANEGFDLAIRHTNTPPETHV
AWVLCETRSFLLASPDYLQRRGTPSHPSELTSHDCLLYLGGSHAGSWTFVRNSKRKSGERVGVTITGTLKANNSEVLRDA
LLAGLGIGLLPDFSLPEGCAPTLFTSCNTLPPEGAALARGGPARRAAREKHPPLVQVLPDWQAQGFFGERIYALRPWSPQ
VPKAVQCFVEHLRQSFAQGFAGVAGGQPPARS
>Mature_351_residues
SSDQLSPLVADLHLLTVLAATRSFTEAARRLGVSKASASTRISELERAAGVSLVRRTTRSVGLTEAGQQLVNEMQPAFNR
ISESYTAVRDLVGTPRGLIRVTAPVALGRQHLAPCVAAFLKRFPDIHIELELTDRFVNLANEGFDLAIRHTNTPPETHVA
WVLCETRSFLLASPDYLQRRGTPSHPSELTSHDCLLYLGGSHAGSWTFVRNSKRKSGERVGVTITGTLKANNSEVLRDAL
LAGLGIGLLPDFSLPEGCAPTLFTSCNTLPPEGAALARGGPARRAAREKHPPLVQVLPDWQAQGFFGERIYALRPWSPQV
PKAVQCFVEHLRQSFAQGFAGVAGGQPPARS

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=252, Percent_Identity=30.5555555555556, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI87081978, Length=334, Percent_Identity=28.4431137724551, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1787589, Length=245, Percent_Identity=32.6530612244898, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1787128, Length=243, Percent_Identity=28.8065843621399, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786401, Length=249, Percent_Identity=28.1124497991968, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI145693193, Length=325, Percent_Identity=29.2307692307692, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789639, Length=175, Percent_Identity=30.2857142857143, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790011, Length=271, Percent_Identity=25.830258302583, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788706, Length=173, Percent_Identity=25.4335260115607, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788748, Length=119, Percent_Identity=31.9327731092437, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789173, Length=148, Percent_Identity=31.7567567567568, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 38093; Mature: 37962

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDQLSPLVADLHLLTVLAATRSFTEAARRLGVSKASASTRISELERAAGVSLVRRTTR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SVGLTEAGQQLVNEMQPAFNRISESYTAVRDLVGTPRGLIRVTAPVALGRQHLAPCVAAF
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHCHHHHHHHHHHH
LKRFPDIHIELELTDRFVNLANEGFDLAIRHTNTPPETHVAWVLCETRSFLLASPDYLQR
HHHCCCEEEEEEEHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCCEECCCHHHHH
RGTPSHPSELTSHDCLLYLGGSHAGSWTFVRNSKRKSGERVGVTITGTLKANNSEVLRDA
CCCCCCCHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCEEEEEEEEEEECCCHHHHHHH
LLAGLGIGLLPDFSLPEGCAPTLFTSCNTLPPEGAALARGGPARRAAREKHPPLVQVLPD
HHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCC
WQAQGFFGERIYALRPWSPQVPKAVQCFVEHLRQSFAQGFAGVAGGQPPARS
CCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SSDQLSPLVADLHLLTVLAATRSFTEAARRLGVSKASASTRISELERAAGVSLVRRTTR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SVGLTEAGQQLVNEMQPAFNRISESYTAVRDLVGTPRGLIRVTAPVALGRQHLAPCVAAF
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHCHHHHHHHHHHH
LKRFPDIHIELELTDRFVNLANEGFDLAIRHTNTPPETHVAWVLCETRSFLLASPDYLQR
HHHCCCEEEEEEEHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCCEECCCHHHHH
RGTPSHPSELTSHDCLLYLGGSHAGSWTFVRNSKRKSGERVGVTITGTLKANNSEVLRDA
CCCCCCCHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCEEEEEEEEEEECCCHHHHHHH
LLAGLGIGLLPDFSLPEGCAPTLFTSCNTLPPEGAALARGGPARRAAREKHPPLVQVLPD
HHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCC
WQAQGFFGERIYALRPWSPQVPKAVQCFVEHLRQSFAQGFAGVAGGQPPARS
CCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]