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The map label for this gene is sdaA [H]

Identifier: 91790204

GI number: 91790204

Start: 4610728

End: 4612122

Strand: Direct

Name: sdaA [H]

Synonym: Bpro_4369

Alternate gene names: 91790204

Gene position: 4610728-4612122 (Clockwise)

Preceding gene: 91790202

Following gene: 91790216

Centisome position: 88.66

GC content: 56.7

Gene sequence:

>1395_bases
GTGGCGGTCAGCGTTTTCGATCTTTTCAAGATAGGTATTGGCCCTTCGAGTTCACACACGGTCGGACCGATGCGTGCGGC
GCGCATGTTCACGCAGCGCTTGGTGAATGAGAACAAGTTGGACACAACGGCGCTCGTGAGATGCGAGCTCTACGGATCGC
TCGGCGCGACCGGCAAAGGCCATGGCAGTGGAACCGCCGTATTACTAGGGCTTTCTGGTTTTGAGCCAGACACGATCGAT
CCGGATAAGATTCCTTCAATCCTAGAGCGTATCCGCTCCACCAATCAGATCCTGCTGCTTGGAGTTCACCCCATCACCTT
CGATGAGAAAGTGGATGTTCTCTTCTTTCTTTCTAAGACGCTTCCGTTTCATGCAAATGGCATGACGTTCTCAGCGTTTC
ACGCATCGGGCGAGCTCCTATGCTCGTATACATACTACTCAGTGGGCGGCGGATTTGTCGTAAGCGAAGAAGTAGCCGGC
GACGGGTCTCGACACAAGACCATCGCGCCGGATACCACCGTGCTTTCACATCCTTTTCACAGTGGCGATGAGTTGCTGGC
CATTGCGAACATAAACCATTGCAGCATCGCAGAGATCATGCGACGGAACGAACGGTACTGGCGGACTGACGCCGAGATTG
ATCGCGGCCTACTTAACATCTGGTCCGTCATGCAGGACTGCGTCACGCGTGGCTGCCGTGCTGAGGGCACACTGCCTGGA
CCCTTTAAGGTCCGTCGCCGTGCCGCCACTTTGCAACAGTCACTATTGGCAGCGCCAAAAACTGGTGCAAAGCCAGATCC
GCTGAGCGCGATAGACTGGATTAACCTGTATGCATTGGCTGTCAACGAAGAGAATGCGTCTGGTGGGCGAGTCGTCACGG
CACCGACGAACGGTGCCGCGGGCATCATCCCTGCCGTATTGCATTACTACACAGGCTTCGTGCATGGCGCCAACGATGCC
GGCGTGATTGAGTTTTTACTCACCGCCGGCGCTATTGGCCTTCTTTACAAGGAGAACGCCTCCATCTCGGGAGCCGAGGT
CGGTTGCCAGGGCGAGGTGGGGGTCGCATGCTCAATGGCAGCGGCCGCGCTATGCGCCGTGATGGGCGGCACGCCTGAGC
AAGTCGAGAACGCCGCCGAGATCGGCATGGAACATCATCTTGGGCTGACATGCGATCCAGTGGGTGGACTGGTGCAGATT
CCTTGCATTGAGAGAAACGCCATCGCGTCTGTCAAAGCCGTCAATGCCGCGCGCATGGCACTGCATGGCGACGGAGCACA
TCACGTGAGCCTGGACAAAGTCATCAAGACCATGCGCGAGACTGGTGCCGACATGATGACCAAGTACAAAGAGACTTCTC
GCGGCGGTCTCGCAGTGAACATTATTGAGTGCTGA

Upstream 100 bases:

>100_bases
TATTCCTAATGTATACATCAAATAAAGATAAATTGTATTGCCTGAATAGCACCCGTACTATGCACGTTCCTACATTAGTC
ACGAGTGACTTGGAGATTTT

Downstream 100 bases:

>100_bases
TTACGCCACAGGTTTGTCCCGAAGACCGCATGTTGAATTCCGTCGAAATCTAACCCGGGTAGGCCGTACCTTATTAGTTT
TGAATCCAGGCTAAACGCTT

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MAVSVFDLFKIGIGPSSSHTVGPMRAARMFTQRLVNENKLDTTALVRCELYGSLGATGKGHGSGTAVLLGLSGFEPDTID
PDKIPSILERIRSTNQILLLGVHPITFDEKVDVLFFLSKTLPFHANGMTFSAFHASGELLCSYTYYSVGGGFVVSEEVAG
DGSRHKTIAPDTTVLSHPFHSGDELLAIANINHCSIAEIMRRNERYWRTDAEIDRGLLNIWSVMQDCVTRGCRAEGTLPG
PFKVRRRAATLQQSLLAAPKTGAKPDPLSAIDWINLYALAVNEENASGGRVVTAPTNGAAGIIPAVLHYYTGFVHGANDA
GVIEFLLTAGAIGLLYKENASISGAEVGCQGEVGVACSMAAAALCAVMGGTPEQVENAAEIGMEHHLGLTCDPVGGLVQI
PCIERNAIASVKAVNAARMALHGDGAHHVSLDKVIKTMRETGADMMTKYKETSRGGLAVNIIEC

Sequences:

>Translated_464_residues
MAVSVFDLFKIGIGPSSSHTVGPMRAARMFTQRLVNENKLDTTALVRCELYGSLGATGKGHGSGTAVLLGLSGFEPDTID
PDKIPSILERIRSTNQILLLGVHPITFDEKVDVLFFLSKTLPFHANGMTFSAFHASGELLCSYTYYSVGGGFVVSEEVAG
DGSRHKTIAPDTTVLSHPFHSGDELLAIANINHCSIAEIMRRNERYWRTDAEIDRGLLNIWSVMQDCVTRGCRAEGTLPG
PFKVRRRAATLQQSLLAAPKTGAKPDPLSAIDWINLYALAVNEENASGGRVVTAPTNGAAGIIPAVLHYYTGFVHGANDA
GVIEFLLTAGAIGLLYKENASISGAEVGCQGEVGVACSMAAAALCAVMGGTPEQVENAAEIGMEHHLGLTCDPVGGLVQI
PCIERNAIASVKAVNAARMALHGDGAHHVSLDKVIKTMRETGADMMTKYKETSRGGLAVNIIEC
>Mature_463_residues
AVSVFDLFKIGIGPSSSHTVGPMRAARMFTQRLVNENKLDTTALVRCELYGSLGATGKGHGSGTAVLLGLSGFEPDTIDP
DKIPSILERIRSTNQILLLGVHPITFDEKVDVLFFLSKTLPFHANGMTFSAFHASGELLCSYTYYSVGGGFVVSEEVAGD
GSRHKTIAPDTTVLSHPFHSGDELLAIANINHCSIAEIMRRNERYWRTDAEIDRGLLNIWSVMQDCVTRGCRAEGTLPGP
FKVRRRAATLQQSLLAAPKTGAKPDPLSAIDWINLYALAVNEENASGGRVVTAPTNGAAGIIPAVLHYYTGFVHGANDAG
VIEFLLTAGAIGLLYKENASISGAEVGCQGEVGVACSMAAAALCAVMGGTPEQVENAAEIGMEHHLGLTCDPVGGLVQIP
CIERNAIASVKAVNAARMALHGDGAHHVSLDKVIKTMRETGADMMTKYKETSRGGLAVNIIEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=460, Percent_Identity=53.2608695652174, Blast_Score=480, Evalue=1e-136,
Organism=Escherichia coli, GI48994925, Length=461, Percent_Identity=54.880694143167, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1789161, Length=464, Percent_Identity=52.5862068965517, Blast_Score=463, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49204; Mature: 49073

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSVFDLFKIGIGPSSSHTVGPMRAARMFTQRLVNENKLDTTALVRCELYGSLGATGKG
CEEEHEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCC
HGSGTAVLLGLSGFEPDTIDPDKIPSILERIRSTNQILLLGVHPITFDEKVDVLFFLSKT
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECC
LPFHANGMTFSAFHASGELLCSYTYYSVGGGFVVSEEVAGDGSRHKTIAPDTTVLSHPFH
CCCCCCCEEEEEEECCCCEEEEEEEEECCCCEEEEHHHCCCCCCCCCCCCCCCEECCCCC
SGDELLAIANINHCSIAEIMRRNERYWRTDAEIDRGLLNIWSVMQDCVTRGCRAEGTLPG
CCCCEEEEECCCCHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PFKVRRRAATLQQSLLAAPKTGAKPDPLSAIDWINLYALAVNEENASGGRVVTAPTNGAA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEEEEEECCCCCCCEEEECCCCCCC
GIIPAVLHYYTGFVHGANDAGVIEFLLTAGAIGLLYKENASISGAEVGCQGEVGVACSMA
HHHHHHHHHHHCEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHH
AAALCAVMGGTPEQVENAAEIGMEHHLGLTCDPVGGLVQIPCIERNAIASVKAVNAARMA
HHHHHHHHCCCHHHHHHHHHHCHHHCCCEEECCCCCEEEECCCCCCHHHHHHHHHHHEEE
LHGDGAHHVSLDKVIKTMRETGADMMTKYKETSRGGLAVNIIEC
EECCCCCEEEHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEEC
>Mature Secondary Structure 
AVSVFDLFKIGIGPSSSHTVGPMRAARMFTQRLVNENKLDTTALVRCELYGSLGATGKG
EEEHEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCC
HGSGTAVLLGLSGFEPDTIDPDKIPSILERIRSTNQILLLGVHPITFDEKVDVLFFLSKT
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECC
LPFHANGMTFSAFHASGELLCSYTYYSVGGGFVVSEEVAGDGSRHKTIAPDTTVLSHPFH
CCCCCCCEEEEEEECCCCEEEEEEEEECCCCEEEEHHHCCCCCCCCCCCCCCCEECCCCC
SGDELLAIANINHCSIAEIMRRNERYWRTDAEIDRGLLNIWSVMQDCVTRGCRAEGTLPG
CCCCEEEEECCCCHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PFKVRRRAATLQQSLLAAPKTGAKPDPLSAIDWINLYALAVNEENASGGRVVTAPTNGAA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEEEEEECCCCCCCEEEECCCCCCC
GIIPAVLHYYTGFVHGANDAGVIEFLLTAGAIGLLYKENASISGAEVGCQGEVGVACSMA
HHHHHHHHHHHCEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHH
AAALCAVMGGTPEQVENAAEIGMEHHLGLTCDPVGGLVQIPCIERNAIASVKAVNAARMA
HHHHHHHHCCCHHHHHHHHHHCHHHCCCEEECCCCCEEEECCCCCCHHHHHHHHHHHEEE
LHGDGAHHVSLDKVIKTMRETGADMMTKYKETSRGGLAVNIIEC
EECCCCCEEEHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]