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The map label for this gene is dppA [H]

Identifier: 91790179

GI number: 91790179

Start: 4581047

End: 4582627

Strand: Reverse

Name: dppA [H]

Synonym: Bpro_4344

Alternate gene names: 91790179

Gene position: 4582627-4581047 (Counterclockwise)

Preceding gene: 91790180

Following gene: 91790178

Centisome position: 88.12

GC content: 57.12

Gene sequence:

>1581_bases
ATGAAACTTCCTGTTCTCACCATTAAGACGACCGCGTTTGCCGCCCTCTTGGCGTTCAGTGGCATCTGTCCGCCTGCGTT
CGCCCAAGCTAAGGACCGCCCTGTGCTTAGCATCAGTTCGGACGCAACAGATATCTCAACGCTCGACCCGCACCGCGCGA
CAACTTCGGACGACAAGGGCGTCGCGTCGCAAGTGTTCAACGGCCTGGTGCGCTTTCCACCGGGCAGCGCCGATCCAAAA
GAGCTTCAGCCCGATCTCGCGGAAAAGTGGCAATCATCCCCCGACAAAAGGACTTGGACGTTCTATCTGCGCAAGGGTGT
GCAGTTCCATGGTGGATATGGCGAGGTGAAGGCCGCTGACGTTGTGTATTCGTTCATGCGTGCAGCCGACAAAGGTCGAT
CCAGTTTTGCAGCGAACTTCGAAGTCATCGAAAAAGTTGAGGCGCGGGACGACTACACCGTGCGTTTCTTGCTGAAGTAT
CCGGACGCCGCGTTCCTCGGTCGCGTATCGAATTACCACGCTGGCAACATCGTTAGTCAGGCGGCGGCCGAAAAACTCGG
GGACAGATTCGGTCAGTCACCGATCGGCACCGGTCCATTTGCATTCAGCGAACACGTTACGCAGCAATATGTGAAGTTGG
TCGCTAACGACGCGTACTTCCGTGGCGCGCCAAAACTGGCCGCCATTACCTATCGCATGATTCCGTCGGACAGCGCGCGT
GAACTGGCGTTTACGTCCAAAGAAGTCGACATGATGAGTGGTAAGCGGGAGCAACGCTGGGTGGACGGCGCGAGCAAACG
CGGCATGAAGGTCGATGTCTTTGACCCTGCCGAGTTCCGTACGCTTCACATCAATCGCACCATTAAGCCCTTGGATAATC
TGAAGGTGCGCCAGGCAATCGCTGCGGCGGTCAACGTGGACGAAATCCTGAGGTATGTCGGCAAAAGTGTGGGCGACAAA
GGCTGCTCGATCATCCCCAACGGCTATCTAGGCGAGGATTGCAGCGCGGGGGGCTACACCTATGACGTTGCGCGCGCCAA
GAAATTGTTGACCGAAGCCGGTTTTCCTAACGGAATTTCTATCAAGTCGGTGGTGTCGAACGTCTCTGCGCAGCAACCCA
TCATGCAAATTGTCCAGTCACAGCTGGCCAAAGCCGGCATCAAGCTGGAAATGGAGGTCGTGGACCATGCGACCTATCAA
GCCAAAAGCCGGAAAGACCAAAGCGCATTGGTGTTCTATGGCGCGGCTCGTTTTCCTATCGCAGATGTCTGGCTCACGGA
GTTCTACGACTCGGCCGCCTCCATTGGGGCGCCTAAGGCAATTTCCAACTTCTCGCATTGCTCCGTGGGTGACGACGCCA
TCCGGCAGGCGCGCATTGAGCCTGATGCGCAGAAGCAGCTGGCATTGTGGAAACAAGCGCAGCAAAAGATCCATGCGGAT
GTCTGCTCCGTGCCGCTCTTTGGCCTGAAGCAAGTGTGGGTGCATAGCGACCGCGTGAACTACGGCTATACGCTGAAAGG
CGCCCTGAACCTACAGCCGCCCATCACCGAACTGGCGACCGTTACGCGGAGCGCACCTTGA

Upstream 100 bases:

>100_bases
TCCAAAAAGCGCCGCAGCTCAGTAACATGAATGACATTCAGACGCATAACCACACGAATTCCGTGTGATGTTCTTCCACC
TTTTTCTAGGAGCAAAGACG

Downstream 100 bases:

>100_bases
GTCTCAAAGTCGTCCATCCCTTGCCCTTTGGTCAATTACTTGGAGTCCAGAGCGGCAGCCCTATGAACCGCAATTCGAAA
GATTGTGGTCGGAGTGGTGG

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MKLPVLTIKTTAFAALLAFSGICPPAFAQAKDRPVLSISSDATDISTLDPHRATTSDDKGVASQVFNGLVRFPPGSADPK
ELQPDLAEKWQSSPDKRTWTFYLRKGVQFHGGYGEVKAADVVYSFMRAADKGRSSFAANFEVIEKVEARDDYTVRFLLKY
PDAAFLGRVSNYHAGNIVSQAAAEKLGDRFGQSPIGTGPFAFSEHVTQQYVKLVANDAYFRGAPKLAAITYRMIPSDSAR
ELAFTSKEVDMMSGKREQRWVDGASKRGMKVDVFDPAEFRTLHINRTIKPLDNLKVRQAIAAAVNVDEILRYVGKSVGDK
GCSIIPNGYLGEDCSAGGYTYDVARAKKLLTEAGFPNGISIKSVVSNVSAQQPIMQIVQSQLAKAGIKLEMEVVDHATYQ
AKSRKDQSALVFYGAARFPIADVWLTEFYDSAASIGAPKAISNFSHCSVGDDAIRQARIEPDAQKQLALWKQAQQKIHAD
VCSVPLFGLKQVWVHSDRVNYGYTLKGALNLQPPITELATVTRSAP

Sequences:

>Translated_526_residues
MKLPVLTIKTTAFAALLAFSGICPPAFAQAKDRPVLSISSDATDISTLDPHRATTSDDKGVASQVFNGLVRFPPGSADPK
ELQPDLAEKWQSSPDKRTWTFYLRKGVQFHGGYGEVKAADVVYSFMRAADKGRSSFAANFEVIEKVEARDDYTVRFLLKY
PDAAFLGRVSNYHAGNIVSQAAAEKLGDRFGQSPIGTGPFAFSEHVTQQYVKLVANDAYFRGAPKLAAITYRMIPSDSAR
ELAFTSKEVDMMSGKREQRWVDGASKRGMKVDVFDPAEFRTLHINRTIKPLDNLKVRQAIAAAVNVDEILRYVGKSVGDK
GCSIIPNGYLGEDCSAGGYTYDVARAKKLLTEAGFPNGISIKSVVSNVSAQQPIMQIVQSQLAKAGIKLEMEVVDHATYQ
AKSRKDQSALVFYGAARFPIADVWLTEFYDSAASIGAPKAISNFSHCSVGDDAIRQARIEPDAQKQLALWKQAQQKIHAD
VCSVPLFGLKQVWVHSDRVNYGYTLKGALNLQPPITELATVTRSAP
>Mature_526_residues
MKLPVLTIKTTAFAALLAFSGICPPAFAQAKDRPVLSISSDATDISTLDPHRATTSDDKGVASQVFNGLVRFPPGSADPK
ELQPDLAEKWQSSPDKRTWTFYLRKGVQFHGGYGEVKAADVVYSFMRAADKGRSSFAANFEVIEKVEARDDYTVRFLLKY
PDAAFLGRVSNYHAGNIVSQAAAEKLGDRFGQSPIGTGPFAFSEHVTQQYVKLVANDAYFRGAPKLAAITYRMIPSDSAR
ELAFTSKEVDMMSGKREQRWVDGASKRGMKVDVFDPAEFRTLHINRTIKPLDNLKVRQAIAAAVNVDEILRYVGKSVGDK
GCSIIPNGYLGEDCSAGGYTYDVARAKKLLTEAGFPNGISIKSVVSNVSAQQPIMQIVQSQLAKAGIKLEMEVVDHATYQ
AKSRKDQSALVFYGAARFPIADVWLTEFYDSAASIGAPKAISNFSHCSVGDDAIRQARIEPDAQKQLALWKQAQQKIHAD
VCSVPLFGLKQVWVHSDRVNYGYTLKGALNLQPPITELATVTRSAP

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=463, Percent_Identity=28.5097192224622, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787052, Length=469, Percent_Identity=29.4243070362473, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1787762, Length=455, Percent_Identity=26.1538461538462, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1787551, Length=370, Percent_Identity=23.5135135135135, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789887, Length=513, Percent_Identity=23.7816764132554, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787495, Length=484, Percent_Identity=21.900826446281, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1786650, Length=229, Percent_Identity=26.6375545851528, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57520; Mature: 57520

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPVLTIKTTAFAALLAFSGICPPAFAQAKDRPVLSISSDATDISTLDPHRATTSDDKG
CCCCEEEEHHHHHHHHHHHHCCCCHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCH
VASQVFNGLVRFPPGSADPKELQPDLAEKWQSSPDKRTWTFYLRKGVQFHGGYGEVKAAD
HHHHHHHCEEECCCCCCCHHHCCCHHHHHHCCCCCCCEEEEEEECCCEEECCCCCHHHHH
VVYSFMRAADKGRSSFAANFEVIEKVEARDDYTVRFLLKYPDAAFLGRVSNYHAGNIVSQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHCCCCCCCCHHHHH
AAAEKLGDRFGQSPIGTGPFAFSEHVTQQYVKLVANDAYFRGAPKLAAITYRMIPSDSAR
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEECCCCCCH
ELAFTSKEVDMMSGKREQRWVDGASKRGMKVDVFDPAEFRTLHINRTIKPLDNLKVRQAI
HHHHCHHHHHHHCCCHHHHHHCCHHCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHH
AAAVNVDEILRYVGKSVGDKGCSIIPNGYLGEDCSAGGYTYDVARAKKLLTEAGFPNGIS
HHHCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCC
IKSVVSNVSAQQPIMQIVQSQLAKAGIKLEMEVVDHATYQAKSRKDQSALVFYGAARFPI
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCCCCEEEEEECCCCCH
ADVWLTEFYDSAASIGAPKAISNFSHCSVGDDAIRQARIEPDAQKQLALWKQAQQKIHAD
HHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VCSVPLFGLKQVWVHSDRVNYGYTLKGALNLQPPITELATVTRSAP
HHCCCHHHHHHHHEECCCCCCCEEEEEEECCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MKLPVLTIKTTAFAALLAFSGICPPAFAQAKDRPVLSISSDATDISTLDPHRATTSDDKG
CCCCEEEEHHHHHHHHHHHHCCCCHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCH
VASQVFNGLVRFPPGSADPKELQPDLAEKWQSSPDKRTWTFYLRKGVQFHGGYGEVKAAD
HHHHHHHCEEECCCCCCCHHHCCCHHHHHHCCCCCCCEEEEEEECCCEEECCCCCHHHHH
VVYSFMRAADKGRSSFAANFEVIEKVEARDDYTVRFLLKYPDAAFLGRVSNYHAGNIVSQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHCCCCCCCCHHHHH
AAAEKLGDRFGQSPIGTGPFAFSEHVTQQYVKLVANDAYFRGAPKLAAITYRMIPSDSAR
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEEEECCCCCCH
ELAFTSKEVDMMSGKREQRWVDGASKRGMKVDVFDPAEFRTLHINRTIKPLDNLKVRQAI
HHHHCHHHHHHHCCCHHHHHHCCHHCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHH
AAAVNVDEILRYVGKSVGDKGCSIIPNGYLGEDCSAGGYTYDVARAKKLLTEAGFPNGIS
HHHCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCC
IKSVVSNVSAQQPIMQIVQSQLAKAGIKLEMEVVDHATYQAKSRKDQSALVFYGAARFPI
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCCCCEEEEEECCCCCH
ADVWLTEFYDSAASIGAPKAISNFSHCSVGDDAIRQARIEPDAQKQLALWKQAQQKIHAD
HHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VCSVPLFGLKQVWVHSDRVNYGYTLKGALNLQPPITELATVTRSAP
HHCCCHHHHHHHHEECCCCCCCEEEEEEECCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]