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The map label for this gene is yajO [H]

Identifier: 91790087

GI number: 91790087

Start: 4475046

End: 4476077

Strand: Reverse

Name: yajO [H]

Synonym: Bpro_4249

Alternate gene names: 91790087

Gene position: 4476077-4475046 (Counterclockwise)

Preceding gene: 91790088

Following gene: 91790086

Centisome position: 86.07

GC content: 66.96

Gene sequence:

>1032_bases
ATGGAACACCGCTATCTCGGCAACTCCGGCTTCAAGGTGCCAGCCCTCGGCTTCGGCACCGGCACCTTTGGCGGCCAGGG
CCCGCTCTTCAGCGCCTGGGGCAACACCGACGTGGCCGGCGCGCGCCGGATCATCGACATCTGCCTGGACGCAGGCGTCA
ACCTGTTCGACACGGCTGACGTGTATTCGAACGGGGCTTCCGAATCCATCCTCGGCGCCGCGCTGAAGGGCCGGCGCGAC
AAGGCCATCGTCTCGACCAAGCTCTCGCTGCGCATCGGCGAGGGGCCGAACGACGTCGGCTCCTCGCGCCATCACCTGAT
AGCGGCCACGAACGCGGCGCTGCAGCGGCTGGACACGGACTACATCGACATCTTGCAGCTGCATGCCTTCGATGCGATGA
CGCCGGTGGAGCAGGTGCTCGGCACGCTCGACGACCTGGTGCGCGCAGGCAAGGTACGTTACATCGGCCTCTCGAACTTC
TCCGGCTGGCAACTGATGAAATCGCTGGCTGCCGCAGACCGTTTGGGGCTGCAGCGTTACGTTGCGAACCAGACCTACTA
CTCGCTGATCGGCCGCGACTACGAGTGGGAGCTGATGCCGCTCGGCATCGACCAGGGCGTGGGCGCGATTGTCTGGAGTC
CGCTCGGCTGGGGCCGCCTGACCGGAAAAATCCGGCGCGGCCAGCCACTGCCTGCGGGCAGTCGCTTGCACGATACGGCC
GGCTTCGCGCCGCCGGTCGATGACGAGCGCCTGTACCGCGTGGTCGATGCGATGGACGAGGTCGCGCTGGAGACCGGCAA
GACGCTGCCGCAGATTGCGCTCAACTGGCTGCTGCAGCGGCCCACCGTCGCAAGTGTGCTGATCGGTGCGCGCGACGAGG
AGCAACTGATGCAGAACCTTGGCGCGCTCGGCTGGCAACTCACGACCGAGCAGGTCGCGCGGCTCGACGCGGCCAGCGCC
GTGACGCCGCCCTATCCCTACTACCCGTACTGGAACGGGCAGTTTGCTGAGCGCAGCCCGGTGGCGGTATAG

Upstream 100 bases:

>100_bases
CACTCGATATGCGCGCTGCCCCGCCTGAAGGTGCCGCCGTGCGCGCCTGAGCGATCTTTTCCCTTTCCTATTCAGTTTCA
CGCTACACAAGGACTTCAAC

Downstream 100 bases:

>100_bases
CGAAGAAGTCCGGCCGCCATGCCCGCCGTCTGCTGATAGAGGTGGTGCAATACCTCAAAAAGGCAAGCCCCCAAACCGGC
GGTAACCAGCTTGAGGGCTT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MEHRYLGNSGFKVPALGFGTGTFGGQGPLFSAWGNTDVAGARRIIDICLDAGVNLFDTADVYSNGASESILGAALKGRRD
KAIVSTKLSLRIGEGPNDVGSSRHHLIAATNAALQRLDTDYIDILQLHAFDAMTPVEQVLGTLDDLVRAGKVRYIGLSNF
SGWQLMKSLAAADRLGLQRYVANQTYYSLIGRDYEWELMPLGIDQGVGAIVWSPLGWGRLTGKIRRGQPLPAGSRLHDTA
GFAPPVDDERLYRVVDAMDEVALETGKTLPQIALNWLLQRPTVASVLIGARDEEQLMQNLGALGWQLTTEQVARLDAASA
VTPPYPYYPYWNGQFAERSPVAV

Sequences:

>Translated_343_residues
MEHRYLGNSGFKVPALGFGTGTFGGQGPLFSAWGNTDVAGARRIIDICLDAGVNLFDTADVYSNGASESILGAALKGRRD
KAIVSTKLSLRIGEGPNDVGSSRHHLIAATNAALQRLDTDYIDILQLHAFDAMTPVEQVLGTLDDLVRAGKVRYIGLSNF
SGWQLMKSLAAADRLGLQRYVANQTYYSLIGRDYEWELMPLGIDQGVGAIVWSPLGWGRLTGKIRRGQPLPAGSRLHDTA
GFAPPVDDERLYRVVDAMDEVALETGKTLPQIALNWLLQRPTVASVLIGARDEEQLMQNLGALGWQLTTEQVARLDAASA
VTPPYPYYPYWNGQFAERSPVAV
>Mature_343_residues
MEHRYLGNSGFKVPALGFGTGTFGGQGPLFSAWGNTDVAGARRIIDICLDAGVNLFDTADVYSNGASESILGAALKGRRD
KAIVSTKLSLRIGEGPNDVGSSRHHLIAATNAALQRLDTDYIDILQLHAFDAMTPVEQVLGTLDDLVRAGKVRYIGLSNF
SGWQLMKSLAAADRLGLQRYVANQTYYSLIGRDYEWELMPLGIDQGVGAIVWSPLGWGRLTGKIRRGQPLPAGSRLHDTA
GFAPPVDDERLYRVVDAMDEVALETGKTLPQIALNWLLQRPTVASVLIGARDEEQLMQNLGALGWQLTTEQVARLDAASA
VTPPYPYYPYWNGQFAERSPVAV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436966, Length=326, Percent_Identity=34.0490797546012, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI27436964, Length=326, Percent_Identity=33.7423312883436, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI27436962, Length=326, Percent_Identity=33.7423312883436, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI27436969, Length=311, Percent_Identity=34.0836012861736, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI4504825, Length=309, Percent_Identity=33.9805825242718, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI27436971, Length=327, Percent_Identity=31.8042813455657, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI223718702, Length=274, Percent_Identity=28.8321167883212, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI41327764, Length=274, Percent_Identity=28.4671532846715, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI41152114, Length=271, Percent_Identity=27.3062730627306, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI87081735, Length=336, Percent_Identity=36.9047619047619, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=31.9148936170213, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789199, Length=362, Percent_Identity=33.1491712707182, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1788070, Length=330, Percent_Identity=33.3333333333333, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1788081, Length=325, Percent_Identity=26.4615384615385, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI48994888, Length=320, Percent_Identity=27.1875, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI212645785, Length=324, Percent_Identity=24.0740740740741, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=350, Percent_Identity=28.2857142857143, Blast_Score=152, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6319958, Length=294, Percent_Identity=29.5918367346939, Blast_Score=135, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6323998, Length=329, Percent_Identity=27.9635258358663, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6322615, Length=256, Percent_Identity=27.734375, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319951, Length=334, Percent_Identity=25.1497005988024, Blast_Score=106, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321052, Length=157, Percent_Identity=29.2993630573248, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640980, Length=324, Percent_Identity=26.5432098765432, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI45549126, Length=324, Percent_Identity=26.5432098765432, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24646155, Length=346, Percent_Identity=26.5895953757225, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646159, Length=317, Percent_Identity=26.4984227129338, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37288; Mature: 37288

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHRYLGNSGFKVPALGFGTGTFGGQGPLFSAWGNTDVAGARRIIDICLDAGVNLFDTAD
CCCCEECCCCCCCCEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEECHH
VYSNGASESILGAALKGRRDKAIVSTKLSLRIGEGPNDVGSSRHHLIAATNAALQRLDTD
HHCCCCCHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHCCH
YIDILQLHAFDAMTPVEQVLGTLDDLVRAGKVRYIGLSNFSGWQLMKSLAAADRLGLQRY
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VANQTYYSLIGRDYEWELMPLGIDQGVGAIVWSPLGWGRLTGKIRRGQPLPAGSRLHDTA
HHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCC
GFAPPVDDERLYRVVDAMDEVALETGKTLPQIALNWLLQRPTVASVLIGARDEEQLMQNL
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHH
GALGWQLTTEQVARLDAASAVTPPYPYYPYWNGQFAERSPVAV
HHCCEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEHRYLGNSGFKVPALGFGTGTFGGQGPLFSAWGNTDVAGARRIIDICLDAGVNLFDTAD
CCCCEECCCCCCCCEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCEEECHH
VYSNGASESILGAALKGRRDKAIVSTKLSLRIGEGPNDVGSSRHHLIAATNAALQRLDTD
HHCCCCCHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHCCH
YIDILQLHAFDAMTPVEQVLGTLDDLVRAGKVRYIGLSNFSGWQLMKSLAAADRLGLQRY
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VANQTYYSLIGRDYEWELMPLGIDQGVGAIVWSPLGWGRLTGKIRRGQPLPAGSRLHDTA
HHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCC
GFAPPVDDERLYRVVDAMDEVALETGKTLPQIALNWLLQRPTVASVLIGARDEEQLMQNL
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHH
GALGWQLTTEQVARLDAASAVTPPYPYYPYWNGQFAERSPVAV
HHCCEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]