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The map label for this gene is cph1 [H]

Identifier: 91790033

GI number: 91790033

Start: 4408913

End: 4410478

Strand: Reverse

Name: cph1 [H]

Synonym: Bpro_4195

Alternate gene names: 91790033

Gene position: 4410478-4408913 (Counterclockwise)

Preceding gene: 91790034

Following gene: 91790030

Centisome position: 84.81

GC content: 63.54

Gene sequence:

>1566_bases
ATGAGCCGATTCCTCAACCTGTTCGGGGTGAAGCTGGCAGACAAGATGCCCGGCCTGGGCGTGCAGAACGGGAGTCGGTC
ATCGGCGCCGGCTGAGCTGGGCTGGGGGCCTCTGGAGCAGTCCGGCGACGGCATGGTGTTGCTCGATGAACGCGGCCGAA
TCACCGAGGCGAATCCCCGCGCGCTCGAACTCCTGCACTGCGCGCAGCCGGCCCTGGCCGGGCTCGATTTCTGGGAGGCC
GTGCCGGAAGACATCACGGAGCAGCATCAGAGCGCCACGGGCCAGGCCCTGACCTTTGCCGCGCGGCACGCCTTTGTTGC
CCACGACAAGTTTGAAGACAAGTGGGTCCGGTACGCCTTTACGAGGCAGCCCCCCGGCTACGTCGTCAGCCTCAGGGATG
TCTCATCCACGCAAAGGTTGCTGGATGTGCTGGAAGACAGCGAGCGTTACAACCAGCTGATTTTTGAGGCGAATCCCAAC
CCGATGTGGATCTTTGACGACAGCTCCACGCGCATCCTCGCTGTCAACCAAGCGGCCGTCGAGTTTTATGGCATTGCGCG
CAAGAAGTTCCTGACGCTGGGCATGGATGCGCTATTTCCCGAGGGAGAAGGCGCTGGATGGCTCAGCTCCCTCGCTTCGG
GCAAAGGCGTCGGGGAGGGGCTGCTCGCGCTGCGCCTGTGCAAACAGCAAAAGGCCGATGGGCAGCAGGTGCTGGTGGAG
CTGGCCTGCGGCCCGGTCAGCTGGAATGGCCAGCAGGCAGTTTTCGTCAGTCTGGCGGATGTCTCACAGCGTCACCTTGC
CGATGGCGCCTTGCGGCGGGCCAATGCGGAGCTGGAACAGGAACTGGCCGGGTGCCAGAGCGAGCTGGAAAAGACCAGGC
GCGATGTGGCCGCCTTCACCCGCGCGGTGTCCCACGACTTGCAGGGGCCGCTGCATGCCGTCAACGGGTTCGCGAAGGTG
CTGGCAAAGAACTACTCGACTGCGCTCGATGCGTCCGGCCTGCATTATGTGAGCCGCATTCAGGCCAGCACGCGCCAGAT
GGCCAAGCTGGTTGATGACCTGCGAACCCTGGTCCAGTTGCCGGAGCTGTCCGGTAACCCTGAAAAATTCGACCTGGTAC
CTATTTGCCGAGCACTGGTCGACGATTTGCGCAAACGCGCCCCGGACCGCAGCGTGGCGATCGAGATGGATGCCAGCCTG
CTGCTCGTTGGTGACAAGGGGTTGTTGACGACGGCGTTGGCCTGCCTGCTGGAAAACGCCTGGAAATTCACCTCCAAAAA
AGCCGAAGCCTGGATCAAGGTCGGGCTGATGCCCGGCGCCACCCCCGGCGAGCTGGTCCTGCTGGTGTCGGACAATGGGG
CGGGCTTTGACACGGCCTACAGCAGCAAACTGTTCACGCCTTTTCAGCGCCTGCACTCTTCTGCTGAATTCCCCGGCAAC
GGTCTGGGCCTGGCTATCGTCAAGCGGGTTGCCGCACGGCACGGCGGCAATGTCTGGGCTGAAACCACCGGCCAGGCAGG
CGCCAGTTTTTACCTGGCGCTACCGCATGCTGCGCAGGCCGCCTGA

Upstream 100 bases:

>100_bases
TCACTGTCATTGGGTTGCGTTACTTCCGGGCTGCCGTACTAGCGGGCGGCACCGGATTCTGAAGCAAGCCAGCCCGCCAA
ACAATCCCCGTGCAATCCCC

Downstream 100 bases:

>100_bases
CGGCCTGAGCCCGTACACACGCCACCCGGCACGCCGTGCCAGCGCAGGCGCCCACCGGGCCTGTCAGGCGTCCGCGGTTC
TCAGCCTGCCCGGGACGTTG

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MSRFLNLFGVKLADKMPGLGVQNGSRSSAPAELGWGPLEQSGDGMVLLDERGRITEANPRALELLHCAQPALAGLDFWEA
VPEDITEQHQSATGQALTFAARHAFVAHDKFEDKWVRYAFTRQPPGYVVSLRDVSSTQRLLDVLEDSERYNQLIFEANPN
PMWIFDDSSTRILAVNQAAVEFYGIARKKFLTLGMDALFPEGEGAGWLSSLASGKGVGEGLLALRLCKQQKADGQQVLVE
LACGPVSWNGQQAVFVSLADVSQRHLADGALRRANAELEQELAGCQSELEKTRRDVAAFTRAVSHDLQGPLHAVNGFAKV
LAKNYSTALDASGLHYVSRIQASTRQMAKLVDDLRTLVQLPELSGNPEKFDLVPICRALVDDLRKRAPDRSVAIEMDASL
LLVGDKGLLTTALACLLENAWKFTSKKAEAWIKVGLMPGATPGELVLLVSDNGAGFDTAYSSKLFTPFQRLHSSAEFPGN
GLGLAIVKRVAARHGGNVWAETTGQAGASFYLALPHAAQAA

Sequences:

>Translated_521_residues
MSRFLNLFGVKLADKMPGLGVQNGSRSSAPAELGWGPLEQSGDGMVLLDERGRITEANPRALELLHCAQPALAGLDFWEA
VPEDITEQHQSATGQALTFAARHAFVAHDKFEDKWVRYAFTRQPPGYVVSLRDVSSTQRLLDVLEDSERYNQLIFEANPN
PMWIFDDSSTRILAVNQAAVEFYGIARKKFLTLGMDALFPEGEGAGWLSSLASGKGVGEGLLALRLCKQQKADGQQVLVE
LACGPVSWNGQQAVFVSLADVSQRHLADGALRRANAELEQELAGCQSELEKTRRDVAAFTRAVSHDLQGPLHAVNGFAKV
LAKNYSTALDASGLHYVSRIQASTRQMAKLVDDLRTLVQLPELSGNPEKFDLVPICRALVDDLRKRAPDRSVAIEMDASL
LLVGDKGLLTTALACLLENAWKFTSKKAEAWIKVGLMPGATPGELVLLVSDNGAGFDTAYSSKLFTPFQRLHSSAEFPGN
GLGLAIVKRVAARHGGNVWAETTGQAGASFYLALPHAAQAA
>Mature_520_residues
SRFLNLFGVKLADKMPGLGVQNGSRSSAPAELGWGPLEQSGDGMVLLDERGRITEANPRALELLHCAQPALAGLDFWEAV
PEDITEQHQSATGQALTFAARHAFVAHDKFEDKWVRYAFTRQPPGYVVSLRDVSSTQRLLDVLEDSERYNQLIFEANPNP
MWIFDDSSTRILAVNQAAVEFYGIARKKFLTLGMDALFPEGEGAGWLSSLASGKGVGEGLLALRLCKQQKADGQQVLVEL
ACGPVSWNGQQAVFVSLADVSQRHLADGALRRANAELEQELAGCQSELEKTRRDVAAFTRAVSHDLQGPLHAVNGFAKVL
AKNYSTALDASGLHYVSRIQASTRQMAKLVDDLRTLVQLPELSGNPEKFDLVPICRALVDDLRKRAPDRSVAIEMDASLL
LVGDKGLLTTALACLLENAWKFTSKKAEAWIKVGLMPGATPGELVLLVSDNGAGFDTAYSSKLFTPFQRLHSSAEFPGNG
LGLAIVKRVAARHGGNVWAETTGQAGASFYLALPHAAQAA

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=248, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1786912, Length=254, Percent_Identity=28.3464566929134, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=26.4227642276423, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=24.5967741935484, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI145693157, Length=277, Percent_Identity=22.7436823104693, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=26.8085106382979, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=282, Percent_Identity=23.758865248227, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56361; Mature: 56229

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFLNLFGVKLADKMPGLGVQNGSRSSAPAELGWGPLEQSGDGMVLLDERGRITEANPR
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCH
ALELLHCAQPALAGLDFWEAVPEDITEQHQSATGQALTFAARHAFVAHDKFEDKWVRYAF
HHHHHHHHCHHHHCCHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHEEEEE
TRQPPGYVVSLRDVSSTQRLLDVLEDSERYNQLIFEANPNPMWIFDDSSTRILAVNQAAV
ECCCCCEEEEECCHHHHHHHHHHHHCCHHHCEEEEECCCCEEEEECCCCCEEEEECHHHH
EFYGIARKKFLTLGMDALFPEGEGAGWLSSLASGKGVGEGLLALRLCKQQKADGQQVLVE
HHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHH
LACGPVSWNGQQAVFVSLADVSQRHLADGALRRANAELEQELAGCQSELEKTRRDVAAFT
HHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVSHDLQGPLHAVNGFAKVLAKNYSTALDASGLHYVSRIQASTRQMAKLVDDLRTLVQL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PELSGNPEKFDLVPICRALVDDLRKRAPDRSVAIEMDASLLLVGDKGLLTTALACLLENA
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCHHHHHHHHHHHHH
WKFTSKKAEAWIKVGLMPGATPGELVLLVSDNGAGFDTAYSSKLFTPFQRLHSSAEFPGN
HHHHHHHHCEEEEEECCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GLGLAIVKRVAARHGGNVWAETTGQAGASFYLALPHAAQAA
CHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCHHCCC
>Mature Secondary Structure 
SRFLNLFGVKLADKMPGLGVQNGSRSSAPAELGWGPLEQSGDGMVLLDERGRITEANPR
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCH
ALELLHCAQPALAGLDFWEAVPEDITEQHQSATGQALTFAARHAFVAHDKFEDKWVRYAF
HHHHHHHHCHHHHCCHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHEEEEE
TRQPPGYVVSLRDVSSTQRLLDVLEDSERYNQLIFEANPNPMWIFDDSSTRILAVNQAAV
ECCCCCEEEEECCHHHHHHHHHHHHCCHHHCEEEEECCCCEEEEECCCCCEEEEECHHHH
EFYGIARKKFLTLGMDALFPEGEGAGWLSSLASGKGVGEGLLALRLCKQQKADGQQVLVE
HHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHH
LACGPVSWNGQQAVFVSLADVSQRHLADGALRRANAELEQELAGCQSELEKTRRDVAAFT
HHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVSHDLQGPLHAVNGFAKVLAKNYSTALDASGLHYVSRIQASTRQMAKLVDDLRTLVQL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PELSGNPEKFDLVPICRALVDDLRKRAPDRSVAIEMDASLLLVGDKGLLTTALACLLENA
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCHHHHHHHHHHHHH
WKFTSKKAEAWIKVGLMPGATPGELVLLVSDNGAGFDTAYSSKLFTPFQRLHSSAEFPGN
HHHHHHHHCEEEEEECCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GLGLAIVKRVAARHGGNVWAETTGQAGASFYLALPHAAQAA
CHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]