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The map label for this gene is gylR [H]

Identifier: 91789702

GI number: 91789702

Start: 4050393

End: 4051229

Strand: Direct

Name: gylR [H]

Synonym: Bpro_3858

Alternate gene names: 91789702

Gene position: 4050393-4051229 (Clockwise)

Preceding gene: 91789701

Following gene: 91789709

Centisome position: 77.89

GC content: 58.66

Gene sequence:

>837_bases
GTGACCTTGGAAAAAGAAACCGCGAACTCGCTCGATTCCGTAGCGGTGGTAGCCCAATTGCTGGATGAATTGGCCGCCGC
GCCAGCACCCATGGGGGTCAGTGAAATAGCCCGCGCCCTGAACCAGTCCAAGGCACGGATTCACCGCAATCTGGTTTCGC
TCAAACACTTTGGTCTGATTGACCAGGACGAAGCCACCGAAAAATACCGCCTGGGCTGGAAGTTGTTTCAGCTTGGCGAA
CGCGCTGGCGTGCAATCGAACATTCGTGCAATAGCCGCCCCTTATCTCAAACTTCTATGTGAAACCACCGGGCAGAGTTC
GCTGCTGTCCATTCCACTCAATGGTGAGGCGCTGGTCATCGCTGCGGTGGACAATGAGAGCAACGTCAGCATCACCGTCA
AACCCGGCAACCGTCCGCTCCCCCACTGCTCGGCCCAGGGTCGCATCGCATTGGCCTATGCAACCGACACACAACGGGAA
CGCCTGCTGAGCGGGCCTCTGCTAGCCCCCACACCGCATTCGCTGGTTGACATCCACGCCATTGATCTGCGCCTGCAACG
CATCCGTGAGCACTTAATGGAAGACGCGCCCAACGAGGCCTTGACAGGTATCAACGTACTTGCCGCCCCCATCCTGCGCA
GTGCCAAAGACCTGATAGGAATCGTCGCCATCGTCGGCTCCATCCAGAACATTCCGCCTTCACCGGCCGGCACTATGGCT
GACATGGTTCGGGGCTGTGCAGCAGCGCTGTCAAAACTGTTTGGCTGCGATGCGTATGAACAGCACGGCATCGCCATCCC
TCCTGAAGTACGCCGCCTGATGCCCAGCGGGAGATGA

Upstream 100 bases:

>100_bases
ATCTGGGATACAGCGAAGCCGACGTGCGGAAAATGGTGTCTACCAATGCAGCTGATCTAATCGGACTGAAATAAATGCAT
TTACCGGGAAGGGTACTGCC

Downstream 100 bases:

>100_bases
TTTCGCTTGCAGTCAAACGTGCCGGCAAGAACGGCACGAGTGGTGAAAGTCAACCCTATCCTTCCTGGCACTGGCGTTTT
CTCCAGCCTCACGCCGCTGT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MTLEKETANSLDSVAVVAQLLDELAAAPAPMGVSEIARALNQSKARIHRNLVSLKHFGLIDQDEATEKYRLGWKLFQLGE
RAGVQSNIRAIAAPYLKLLCETTGQSSLLSIPLNGEALVIAAVDNESNVSITVKPGNRPLPHCSAQGRIALAYATDTQRE
RLLSGPLLAPTPHSLVDIHAIDLRLQRIREHLMEDAPNEALTGINVLAAPILRSAKDLIGIVAIVGSIQNIPPSPAGTMA
DMVRGCAAALSKLFGCDAYEQHGIAIPPEVRRLMPSGR

Sequences:

>Translated_278_residues
MTLEKETANSLDSVAVVAQLLDELAAAPAPMGVSEIARALNQSKARIHRNLVSLKHFGLIDQDEATEKYRLGWKLFQLGE
RAGVQSNIRAIAAPYLKLLCETTGQSSLLSIPLNGEALVIAAVDNESNVSITVKPGNRPLPHCSAQGRIALAYATDTQRE
RLLSGPLLAPTPHSLVDIHAIDLRLQRIREHLMEDAPNEALTGINVLAAPILRSAKDLIGIVAIVGSIQNIPPSPAGTMA
DMVRGCAAALSKLFGCDAYEQHGIAIPPEVRRLMPSGR
>Mature_277_residues
TLEKETANSLDSVAVVAQLLDELAAAPAPMGVSEIARALNQSKARIHRNLVSLKHFGLIDQDEATEKYRLGWKLFQLGER
AGVQSNIRAIAAPYLKLLCETTGQSSLLSIPLNGEALVIAAVDNESNVSITVKPGNRPLPHCSAQGRIALAYATDTQRER
LLSGPLLAPTPHSLVDIHAIDLRLQRIREHLMEDAPNEALTGINVLAAPILRSAKDLIGIVAIVGSIQNIPPSPAGTMAD
MVRGCAAALSKLFGCDAYEQHGIAIPPEVRRLMPSGR

Specific function: May be an activator protein for the gylABX operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=251, Percent_Identity=24.7011952191235, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788131, Length=214, Percent_Identity=24.7663551401869, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29743; Mature: 29612

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLEKETANSLDSVAVVAQLLDELAAAPAPMGVSEIARALNQSKARIHRNLVSLKHFGLI
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DQDEATEKYRLGWKLFQLGERAGVQSNIRAIAAPYLKLLCETTGQSSLLSIPLNGEALVI
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEE
AAVDNESNVSITVKPGNRPLPHCSAQGRIALAYATDTQRERLLSGPLLAPTPHSLVDIHA
EEECCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCHHEEHHH
IDLRLQRIREHLMEDAPNEALTGINVLAAPILRSAKDLIGIVAIVGSIQNIPPSPAGTMA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
DMVRGCAAALSKLFGCDAYEQHGIAIPPEVRRLMPSGR
HHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
TLEKETANSLDSVAVVAQLLDELAAAPAPMGVSEIARALNQSKARIHRNLVSLKHFGLI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DQDEATEKYRLGWKLFQLGERAGVQSNIRAIAAPYLKLLCETTGQSSLLSIPLNGEALVI
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEE
AAVDNESNVSITVKPGNRPLPHCSAQGRIALAYATDTQRERLLSGPLLAPTPHSLVDIHA
EEECCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCHHEEHHH
IDLRLQRIREHLMEDAPNEALTGINVLAAPILRSAKDLIGIVAIVGSIQNIPPSPAGTMA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
DMVRGCAAALSKLFGCDAYEQHGIAIPPEVRRLMPSGR
HHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2110096 [H]