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The map label for this gene is purN [H]

Identifier: 91789687

GI number: 91789687

Start: 4034371

End: 4034970

Strand: Reverse

Name: purN [H]

Synonym: Bpro_3843

Alternate gene names: 91789687

Gene position: 4034970-4034371 (Counterclockwise)

Preceding gene: 91789691

Following gene: 91789686

Centisome position: 77.59

GC content: 64.17

Gene sequence:

>600_bases
ATGGGAAGCAGTCCAAAGGACATCGTTATTTTGATCTCTGGCGGGGGCTCCAACATGGTGGCCATCACGAATGCAGCGCA
AAAAGAGCGGTGGCAGGACACCCTCCATGCCCGCGTGGCCTGCGTCATCAGCAACAAGCCGGGTGCCGAGGGGCTGGCCA
CCGCGGCCGGGCTGGGCATTGCGACCCAGGTGATTGATCACAAGCAATTTGACTCGCGCGATGCGTTTGACGCGGCGCTG
CAGGGCGCTATTGATGCCTGCCAGCCCACGCTGGTGGTGCTGGCTGGCTTCATGCGCATATTGACGCCCGCTTTTGTGGC
GCACTACGCCGGTCGGCTGGTCAATATCCATCCGTCCCTGCTGCCCGCCTTCCCCGGCCTCAACACCCATCAACGGGCCA
TTGATGCGGGCTGCAAGGTGGCCGGTGCCACGGTGCACCTGGTCACTGCCGATCTTGACCACGGCCCCATTCTGGCCCAG
GCGGTGGTGCCCATTCTTGCGGGAGACAGCGCGAACACGCTGGCCGCCCGCGTGCTGAGCCAGGAACACCTGATTTATCC
GCGGGCAATCCGCGCGTTGCTGGAGCAGGCCGCTGGCTGA

Upstream 100 bases:

>100_bases
GAGTGTGCCCAGCACGCGGGCTTCAATCGGGGTCAGGGTTCTGATGGTCATAAACTAGGGTGATATTTGAAAGAGGCACC
AGAAGGTGATAAGAAACAAT

Downstream 100 bases:

>100_bases
TGGGTGCTGATCGCTGATCGCTGAGCGCTGAGCGCTGAGCGCTGAGCCGGCACCGCGTCATGAACCCGGTGTGGCGTTCT
TCTCCTGTCCGGCGGATTCG

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MGSSPKDIVILISGGGSNMVAITNAAQKERWQDTLHARVACVISNKPGAEGLATAAGLGIATQVIDHKQFDSRDAFDAAL
QGAIDACQPTLVVLAGFMRILTPAFVAHYAGRLVNIHPSLLPAFPGLNTHQRAIDAGCKVAGATVHLVTADLDHGPILAQ
AVVPILAGDSANTLAARVLSQEHLIYPRAIRALLEQAAG

Sequences:

>Translated_199_residues
MGSSPKDIVILISGGGSNMVAITNAAQKERWQDTLHARVACVISNKPGAEGLATAAGLGIATQVIDHKQFDSRDAFDAAL
QGAIDACQPTLVVLAGFMRILTPAFVAHYAGRLVNIHPSLLPAFPGLNTHQRAIDAGCKVAGATVHLVTADLDHGPILAQ
AVVPILAGDSANTLAARVLSQEHLIYPRAIRALLEQAAG
>Mature_198_residues
GSSPKDIVILISGGGSNMVAITNAAQKERWQDTLHARVACVISNKPGAEGLATAAGLGIATQVIDHKQFDSRDAFDAALQ
GAIDACQPTLVVLAGFMRILTPAFVAHYAGRLVNIHPSLLPAFPGLNTHQRAIDAGCKVAGATVHLVTADLDHGPILAQA
VVPILAGDSANTLAARVLSQEHLIYPRAIRALLEQAAG

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=184, Percent_Identity=42.3913043478261, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI209869995, Length=184, Percent_Identity=42.3913043478261, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI209869993, Length=184, Percent_Identity=42.3913043478261, Blast_Score=152, Evalue=2e-37,
Organism=Escherichia coli, GI1788846, Length=184, Percent_Identity=53.2608695652174, Blast_Score=190, Evalue=6e-50,
Organism=Escherichia coli, GI1787483, Length=162, Percent_Identity=35.8024691358025, Blast_Score=101, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17567511, Length=186, Percent_Identity=38.7096774193548, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320616, Length=213, Percent_Identity=27.6995305164319, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582400, Length=193, Percent_Identity=45.5958549222798, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 20646; Mature: 20515

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSSPKDIVILISGGGSNMVAITNAAQKERWQDTLHARVACVISNKPGAEGLATAAGLGI
CCCCCCEEEEEEECCCCCEEEEECHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHH
ATQVIDHKQFDSRDAFDAALQGAIDACQPTLVVLAGFMRILTPAFVAHYAGRLVNIHPSL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHH
LPAFPGLNTHQRAIDAGCKVAGATVHLVTADLDHGPILAQAVVPILAGDSANTLAARVLS
HHCCCCCCHHHHHHHHCCEECCCEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
QEHLIYPRAIRALLEQAAG
HHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
GSSPKDIVILISGGGSNMVAITNAAQKERWQDTLHARVACVISNKPGAEGLATAAGLGI
CCCCCEEEEEEECCCCCEEEEECHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHH
ATQVIDHKQFDSRDAFDAALQGAIDACQPTLVVLAGFMRILTPAFVAHYAGRLVNIHPSL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHH
LPAFPGLNTHQRAIDAGCKVAGATVHLVTADLDHGPILAQAVVPILAGDSANTLAARVLS
HHCCCCCCHHHHHHHHCCEECCCEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
QEHLIYPRAIRALLEQAAG
HHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3301838; 9205837; 9278503; 10954745; 2204419; 1522592; 1631098; 9698564; 10606510 [H]