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The map label for this gene is paaG [C]

Identifier: 91789678

GI number: 91789678

Start: 4024479

End: 4025267

Strand: Reverse

Name: paaG [C]

Synonym: Bpro_3834

Alternate gene names: 91789678

Gene position: 4025267-4024479 (Counterclockwise)

Preceding gene: 91789679

Following gene: 91789677

Centisome position: 77.41

GC content: 64.51

Gene sequence:

>789_bases
ATGAGCGCTTCAAATTCAAACCCGGTGATCTTGACATGCGAAGGCGGCATGGCGACGATGACCTTTAACCGCCCCTCGGC
CATGAACGCACTGGACGTGCCGACGGCCAGCGCATTTCTGGCGGCTTGCCAGTCGCTGGCGGACGACCCGCAGCTGCGGG
TGATTGTCATCCGCGGCGAAGGCCGCGCCTTTGGCGTGGGCGGCGACCTGGCAGCGCTGCAGCACGACTCTGCGGCGACG
GCACAAGATCTGATCGGCCGCTTGCACGAGGCGGTCGTGCTGCTGGCCGGACTCAATGCCCCCGTGATTGCCAGCCTGCA
TGGCGTGGTGGCGGGTGGCTCGCTGAGCCTCTCCATGGCCTGCGACCTGGTCATCGCAGCCGACAGTACGCGCTTTAACC
TCGCCTATGCGAATGTCGGTGCCAGCTGTGACGTATCAGGCTCCTGGAGCCTGCCGCGGCTGGTGGGGCTGCGCAACGCG
ATGCAGATTGCCCTGCTGTCGGAAACTTTTGACGCGGCCGAAGCGCTGCGTCTGGGCCTGGTCAACCGCGTGGTACCCGC
TGACAAGTTGCAGGAAGAAACCGTGGCCTTGGCCCGGCGGCTGGCTGCCGGGCCTACCCTGGCCTACGGCCGCATGAAGC
GGCTGATGCGCCAGTCCTTCGAGACCGACTTGCCCACGCAGCTCGACGCTGAACGCGAAAATTTCAAGGCCAGCACGCAG
ACGGAAGATTTCAAGGAAGCCGCGAAGGCCTTCTTTGCCAAACGGCCAGCCGTTTTCAAGGGCCACTAG

Upstream 100 bases:

>100_bases
GAGATCCAGAAATGGGTGATTGCACGCAACATCTTTGGCCGCGCTTACACGGGTTAATTAAGCGCTTGATGACCCGACTC
AGCACAACAGAAAGTACCTC

Downstream 100 bases:

>100_bases
CCCGCGTCATTTCAACCCTTTAAGGCAAACCATGAAGAACCGAATCACTGAATTGCTCGGCATCCGCTACCCCATCATTC
AGGGCGGCATGCAATGGGTG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSASNSNPVILTCEGGMATMTFNRPSAMNALDVPTASAFLAACQSLADDPQLRVIVIRGEGRAFGVGGDLAALQHDSAAT
AQDLIGRLHEAVVLLAGLNAPVIASLHGVVAGGSLSLSMACDLVIAADSTRFNLAYANVGASCDVSGSWSLPRLVGLRNA
MQIALLSETFDAAEALRLGLVNRVVPADKLQEETVALARRLAAGPTLAYGRMKRLMRQSFETDLPTQLDAERENFKASTQ
TEDFKEAAKAFFAKRPAVFKGH

Sequences:

>Translated_262_residues
MSASNSNPVILTCEGGMATMTFNRPSAMNALDVPTASAFLAACQSLADDPQLRVIVIRGEGRAFGVGGDLAALQHDSAAT
AQDLIGRLHEAVVLLAGLNAPVIASLHGVVAGGSLSLSMACDLVIAADSTRFNLAYANVGASCDVSGSWSLPRLVGLRNA
MQIALLSETFDAAEALRLGLVNRVVPADKLQEETVALARRLAAGPTLAYGRMKRLMRQSFETDLPTQLDAERENFKASTQ
TEDFKEAAKAFFAKRPAVFKGH
>Mature_261_residues
SASNSNPVILTCEGGMATMTFNRPSAMNALDVPTASAFLAACQSLADDPQLRVIVIRGEGRAFGVGGDLAALQHDSAATA
QDLIGRLHEAVVLLAGLNAPVIASLHGVVAGGSLSLSMACDLVIAADSTRFNLAYANVGASCDVSGSWSLPRLVGLRNAM
QIALLSETFDAAEALRLGLVNRVVPADKLQEETVALARRLAAGPTLAYGRMKRLMRQSFETDLPTQLDAERENFKASTQT
EDFKEAAKAFFAKRPAVFKGH

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=242, Percent_Identity=29.7520661157025, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI31542718, Length=247, Percent_Identity=27.5303643724696, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI4502327, Length=253, Percent_Identity=28.8537549407115, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI45643119, Length=214, Percent_Identity=24.2990654205607, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI260275230, Length=214, Percent_Identity=24.2990654205607, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI70995211, Length=179, Percent_Identity=29.0502793296089, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI260274832, Length=214, Percent_Identity=24.2990654205607, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI37594471, Length=196, Percent_Identity=27.0408163265306, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI37594469, Length=196, Percent_Identity=27.0408163265306, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI62530384, Length=243, Percent_Identity=24.2798353909465, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI295842266, Length=240, Percent_Identity=24.1666666666667, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787660, Length=252, Percent_Identity=34.1269841269841, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1787659, Length=244, Percent_Identity=34.4262295081967, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI221142681, Length=260, Percent_Identity=31.5384615384615, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788597, Length=256, Percent_Identity=31.25, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082183, Length=256, Percent_Identity=25, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790281, Length=194, Percent_Identity=29.8969072164948, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788682, Length=191, Percent_Identity=31.413612565445, Blast_Score=78, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17554946, Length=239, Percent_Identity=30.9623430962343, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25145438, Length=241, Percent_Identity=30.7053941908714, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17536985, Length=257, Percent_Identity=27.2373540856031, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17540714, Length=221, Percent_Identity=27.1493212669683, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560910, Length=220, Percent_Identity=26.8181818181818, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17534483, Length=249, Percent_Identity=24.8995983935743, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17540306, Length=240, Percent_Identity=26.25, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17549921, Length=204, Percent_Identity=27.9411764705882, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=257, Percent_Identity=24.5136186770428, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI25144160, Length=257, Percent_Identity=25.6809338521401, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25144157, Length=257, Percent_Identity=25.6809338521401, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=212, Percent_Identity=24.0566037735849, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129971, Length=263, Percent_Identity=31.5589353612167, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24653477, Length=263, Percent_Identity=31.5589353612167, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24653139, Length=252, Percent_Identity=28.968253968254, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI19922422, Length=255, Percent_Identity=23.5294117647059, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24654903, Length=257, Percent_Identity=22.568093385214, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19920382, Length=268, Percent_Identity=25.3731343283582, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357171, Length=247, Percent_Identity=25.9109311740891, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24650670, Length=199, Percent_Identity=27.6381909547739, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571730, Length=195, Percent_Identity=25.1282051282051, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571729, Length=195, Percent_Identity=25.1282051282051, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 27616; Mature: 27485

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASNSNPVILTCEGGMATMTFNRPSAMNALDVPTASAFLAACQSLADDPQLRVIVIRGE
CCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECC
GRAFGVGGDLAALQHDSAATAQDLIGRLHEAVVLLAGLNAPVIASLHGVVAGGSLSLSMA
CEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEECCCEEEEEE
CDLVIAADSTRFNLAYANVGASCDVSGSWSLPRLVGLRNAMQIALLSETFDAAEALRLGL
EEEEEEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNRVVPADKLQEETVALARRLAAGPTLAYGRMKRLMRQSFETDLPTQLDAERENFKASTQ
HHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCC
TEDFKEAAKAFFAKRPAVFKGH
HHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SASNSNPVILTCEGGMATMTFNRPSAMNALDVPTASAFLAACQSLADDPQLRVIVIRGE
CCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECC
GRAFGVGGDLAALQHDSAATAQDLIGRLHEAVVLLAGLNAPVIASLHGVVAGGSLSLSMA
CEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEECCCEEEEEE
CDLVIAADSTRFNLAYANVGASCDVSGSWSLPRLVGLRNAMQIALLSETFDAAEALRLGL
EEEEEEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNRVVPADKLQEETVALARRLAAGPTLAYGRMKRLMRQSFETDLPTQLDAERENFKASTQ
HHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCC
TEDFKEAAKAFFAKRPAVFKGH
HHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA