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The map label for this gene is ilvD [H]

Identifier: 91789654

GI number: 91789654

Start: 3998497

End: 4000251

Strand: Direct

Name: ilvD [H]

Synonym: Bpro_3810

Alternate gene names: 91789654

Gene position: 3998497-4000251 (Clockwise)

Preceding gene: 91789653

Following gene: 91789655

Centisome position: 76.89

GC content: 63.25

Gene sequence:

>1755_bases
ATGACCATGAAATCAAGCGACACATCCAAAAACCATTCCGAAGAAACCGGTCTGAGAAAGGGCCTGACCAGCTACGGCGA
CAAGGGCTTCTCGCTCTTTCTTCGAAAGGCTTTCATCAAGGGGGCGGGCTATACCGATACGGCGCTGGACCGGCCTGTGA
TCGGCATTGCCAATACCGGCAGCGCATACAACCCATGCCATGGCAATGCCCCCCAGCTCATTGAGGCCGTCAAGCGTGGT
GTCATGCTGGCAGGCGGGCTGCCCATGGATTTCCCCACGATTTCCATCCACGAGAGCTTCTCGGCGCCGACCAGCATGTA
CCTGCGCAACCTGATGTCGATGGATACGGAGGAGATGGTCCGGGCCCAACCGATGGATGCGGTGGTGCTGATTGGCGGCT
GCGACAAGACGGTTCCGGCGCAGCTGATGGGTGCGGCATCGGCGGGCATTCCGGCCATCCAGTTGATCACGGGATCCATG
CTGACCGGCTCCCACCGGGGCGAGCGTGTCGGTGCGTGTACCGACTGCCGCCGCTATTGGGGCAAGTTCCGCGCCGGCGA
GATCGATGCCGAGGAAACAGCGGATGTCAACAACCAGCTGGTGGCCAGCGTGGGCACCTGCTCGGTGATGGGAACTGCCA
GCACCATGGCCTGCATTGCCGAGGCCCTGGGCATGACGGTTCCGGGCGGCGCATCGCCTCCGGCCGTCACGGCCGACCGC
ATCCGGATCGCGGAGGAGACCGGTGCGCGGGCCGTGCAAATGGCACGCGATGGACTGACCATCGACAAAATCCTGACACC
CGCGGCTTTCGAAAATGCCATGCGGGTGCTGCTGTCCATCGGCGGGTCCACCAACGGCATCGTGCACCTGGCAGCGATTG
CGGGTCGCGTCGGCCTGGAAATTGACATGCAGGCGCTGGATCGCATGGGCAGGGAAACGCCGGTCCTGCTGGACCTCAAA
CCCTCCGGCCAGCACTACATGGAAGACTTCCACAAGGCAGGCGGCATGGCCACGCTGTTCAGGGCGCTCAAGCCCCTGCT
GCGCCTGGATGCATTGACGGTGACGGGACGCACCCTGGGTGAGGAAATTGAACTGGTCGGACCAGGTTTTGCGCAGGATG
TGGTTCGCTCCATCGACAACCCGATCTACCCGCAGGGAGGCATCGCCGTGCTGCGCGGCAACCTGGCGCCAGGCTGCGCC
ATCATCAAGCAATCTGCGGCCGACCCCAAGCTGATGGAGCATGAGGGACGCGCCGTGGTGTTCGACAACGCGGAGGATCT
GGTCAACCGCATCGACCGCGACGACCTGGATGTCATGGCAGACGACGTGCTGGTGCTCAAGAACATCGGCCCCAAGGGGG
CGCCGGGCATGCCCGAGGCTGGCTACATTCCCATTCCGCTCAAACTGGCACGTGCCGGCGTAAAGGACATGGTCAGGATT
TCGGACGGCCGGATGAGCGGCACCGCCTTCGGCACCATCGTCCTGCATGTGACGCCGGAATCCGCCGTGGGTGGGCCACT
GTCGCAGGTGCGCAGTGGAGACCACATTCGGCTCAGCGTGCGCAATCGTGAGATCAGCCTGCTGGTATCCGATGAAGAAC
TCGCCCGGCGGATGCGCGAGAACGTGGTGACCGAGCCGACCGCCGACCGGGGCTATCGCAGGCTGTTCCTGCAGACCGTC
ACGCAAGCCGACAAGGGCGTCGATTTTGACTTTCTGAGGGCCGCAAAGATCACCGGAAAAACGCCTCGATCCTGA

Upstream 100 bases:

>100_bases
CCTGCGCAGCGAAGTGTCTCGCTGGGAAAAGGTCATCAAGGAAGCCAACATCAAGGCAGACGACTGAGCTGTCGGCCACC
GGATATTTTCAAACACCCTC

Downstream 100 bases:

>100_bases
CATGCAGGCTATCGTCAAAATTGGGACCTTTGCCGGAGAGCTTCAGCAGACCATTGACCGGGAATTCCAATGCCATGGGC
CTGAGGATATTGCGCGGGAT

Product: dihydroxy-acid dehydratase

Products: NA

Alternate protein names: DAD [H]

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MTMKSSDTSKNHSEETGLRKGLTSYGDKGFSLFLRKAFIKGAGYTDTALDRPVIGIANTGSAYNPCHGNAPQLIEAVKRG
VMLAGGLPMDFPTISIHESFSAPTSMYLRNLMSMDTEEMVRAQPMDAVVLIGGCDKTVPAQLMGAASAGIPAIQLITGSM
LTGSHRGERVGACTDCRRYWGKFRAGEIDAEETADVNNQLVASVGTCSVMGTASTMACIAEALGMTVPGGASPPAVTADR
IRIAEETGARAVQMARDGLTIDKILTPAAFENAMRVLLSIGGSTNGIVHLAAIAGRVGLEIDMQALDRMGRETPVLLDLK
PSGQHYMEDFHKAGGMATLFRALKPLLRLDALTVTGRTLGEEIELVGPGFAQDVVRSIDNPIYPQGGIAVLRGNLAPGCA
IIKQSAADPKLMEHEGRAVVFDNAEDLVNRIDRDDLDVMADDVLVLKNIGPKGAPGMPEAGYIPIPLKLARAGVKDMVRI
SDGRMSGTAFGTIVLHVTPESAVGGPLSQVRSGDHIRLSVRNREISLLVSDEELARRMRENVVTEPTADRGYRRLFLQTV
TQADKGVDFDFLRAAKITGKTPRS

Sequences:

>Translated_584_residues
MTMKSSDTSKNHSEETGLRKGLTSYGDKGFSLFLRKAFIKGAGYTDTALDRPVIGIANTGSAYNPCHGNAPQLIEAVKRG
VMLAGGLPMDFPTISIHESFSAPTSMYLRNLMSMDTEEMVRAQPMDAVVLIGGCDKTVPAQLMGAASAGIPAIQLITGSM
LTGSHRGERVGACTDCRRYWGKFRAGEIDAEETADVNNQLVASVGTCSVMGTASTMACIAEALGMTVPGGASPPAVTADR
IRIAEETGARAVQMARDGLTIDKILTPAAFENAMRVLLSIGGSTNGIVHLAAIAGRVGLEIDMQALDRMGRETPVLLDLK
PSGQHYMEDFHKAGGMATLFRALKPLLRLDALTVTGRTLGEEIELVGPGFAQDVVRSIDNPIYPQGGIAVLRGNLAPGCA
IIKQSAADPKLMEHEGRAVVFDNAEDLVNRIDRDDLDVMADDVLVLKNIGPKGAPGMPEAGYIPIPLKLARAGVKDMVRI
SDGRMSGTAFGTIVLHVTPESAVGGPLSQVRSGDHIRLSVRNREISLLVSDEELARRMRENVVTEPTADRGYRRLFLQTV
TQADKGVDFDFLRAAKITGKTPRS
>Mature_583_residues
TMKSSDTSKNHSEETGLRKGLTSYGDKGFSLFLRKAFIKGAGYTDTALDRPVIGIANTGSAYNPCHGNAPQLIEAVKRGV
MLAGGLPMDFPTISIHESFSAPTSMYLRNLMSMDTEEMVRAQPMDAVVLIGGCDKTVPAQLMGAASAGIPAIQLITGSML
TGSHRGERVGACTDCRRYWGKFRAGEIDAEETADVNNQLVASVGTCSVMGTASTMACIAEALGMTVPGGASPPAVTADRI
RIAEETGARAVQMARDGLTIDKILTPAAFENAMRVLLSIGGSTNGIVHLAAIAGRVGLEIDMQALDRMGRETPVLLDLKP
SGQHYMEDFHKAGGMATLFRALKPLLRLDALTVTGRTLGEEIELVGPGFAQDVVRSIDNPIYPQGGIAVLRGNLAPGCAI
IKQSAADPKLMEHEGRAVVFDNAEDLVNRIDRDDLDVMADDVLVLKNIGPKGAPGMPEAGYIPIPLKLARAGVKDMVRIS
DGRMSGTAFGTIVLHVTPESAVGGPLSQVRSGDHIRLSVRNREISLLVSDEELARRMRENVVTEPTADRGYRRLFLQTVT
QADKGVDFDFLRAAKITGKTPRS

Specific function: Valine and isoleucine biosynthesis; fourth step. [C]

COG id: COG0129

COG function: function code EG; Dihydroxyacid dehydratase/phosphogluconate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ilvD/edd family [H]

Homologues:

Organism=Escherichia coli, GI48994964, Length=598, Percent_Identity=31.1036789297659, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI2367371, Length=467, Percent_Identity=30.406852248394, Blast_Score=168, Evalue=8e-43,
Organism=Escherichia coli, GI1786464, Length=498, Percent_Identity=29.718875502008, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1788157, Length=459, Percent_Identity=31.1546840958606, Blast_Score=163, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322476, Length=549, Percent_Identity=30.6010928961749, Blast_Score=266, Evalue=5e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015928
- InterPro:   IPR004404
- InterPro:   IPR000581
- InterPro:   IPR020558 [H]

Pfam domain/function: PF00920 ILVD_EDD [H]

EC number: =4.2.1.9 [H]

Molecular weight: Translated: 62227; Mature: 62096

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00886 ILVD_EDD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMKSSDTSKNHSEETGLRKGLTSYGDKGFSLFLRKAFIKGAGYTDTALDRPVIGIANTG
CCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHCCCCEEEEECCC
SAYNPCHGNAPQLIEAVKRGVMLAGGLPMDFPTISIHESFSAPTSMYLRNLMSMDTEEMV
CCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHH
RAQPMDAVVLIGGCDKTVPAQLMGAASAGIPAIQLITGSMLTGSHRGERVGACTDCRRYW
HCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCCCHHHHHHHH
GKFRAGEIDAEETADVNNQLVASVGTCSVMGTASTMACIAEALGMTVPGGASPPAVTADR
CCCCCCCCCCHHHCCCCCHHHHHCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
IRIAEETGARAVQMARDGLTIDKILTPAAFENAMRVLLSIGGSTNGIVHLAAIAGRVGLE
EEEHHHHCHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCCCE
IDMQALDRMGRETPVLLDLKPSGQHYMEDFHKAGGMATLFRALKPLLRLDALTVTGRTLG
EEHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEECCHHCC
EEIELVGPGFAQDVVRSIDNPIYPQGGIAVLRGNLAPGCAIIKQSAADPKLMEHEGRAVV
CCEEEECCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHCCCCCCHHHHCCCCEEE
FDNAEDLVNRIDRDDLDVMADDVLVLKNIGPKGAPGMPEAGYIPIPLKLARAGVKDMVRI
ECCHHHHHHHCCCCCHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHEE
SDGRMSGTAFGTIVLHVTPESAVGGPLSQVRSGDHIRLSVRNREISLLVSDEELARRMRE
CCCCCCCEEEEEEEEEECCCHHCCCCHHHHCCCCEEEEEEECCEEEEEECCHHHHHHHHH
NVVTEPTADRGYRRLFLQTVTQADKGVDFDFLRAAKITGKTPRS
HCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TMKSSDTSKNHSEETGLRKGLTSYGDKGFSLFLRKAFIKGAGYTDTALDRPVIGIANTG
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHCCCCEEEEECCC
SAYNPCHGNAPQLIEAVKRGVMLAGGLPMDFPTISIHESFSAPTSMYLRNLMSMDTEEMV
CCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHCCCHHHHH
RAQPMDAVVLIGGCDKTVPAQLMGAASAGIPAIQLITGSMLTGSHRGERVGACTDCRRYW
HCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCCCHHHHHHHH
GKFRAGEIDAEETADVNNQLVASVGTCSVMGTASTMACIAEALGMTVPGGASPPAVTADR
CCCCCCCCCCHHHCCCCCHHHHHCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
IRIAEETGARAVQMARDGLTIDKILTPAAFENAMRVLLSIGGSTNGIVHLAAIAGRVGLE
EEEHHHHCHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCCCE
IDMQALDRMGRETPVLLDLKPSGQHYMEDFHKAGGMATLFRALKPLLRLDALTVTGRTLG
EEHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEECCHHCC
EEIELVGPGFAQDVVRSIDNPIYPQGGIAVLRGNLAPGCAIIKQSAADPKLMEHEGRAVV
CCEEEECCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHCCCCCCHHHHCCCCEEE
FDNAEDLVNRIDRDDLDVMADDVLVLKNIGPKGAPGMPEAGYIPIPLKLARAGVKDMVRI
ECCHHHHHHHCCCCCHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHEE
SDGRMSGTAFGTIVLHVTPESAVGGPLSQVRSGDHIRLSVRNREISLLVSDEELARRMRE
CCCCCCCEEEEEEEEEECCCHHCCCCHHHHCCCCEEEEEEECCEEEEEECCHHHHHHHHH
NVVTEPTADRGYRRLFLQTVTQADKGVDFDFLRAAKITGKTPRS
HCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA