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The map label for this gene is trxB [H]

Identifier: 91789645

GI number: 91789645

Start: 3988596

End: 3989582

Strand: Direct

Name: trxB [H]

Synonym: Bpro_3801

Alternate gene names: 91789645

Gene position: 3988596-3989582 (Clockwise)

Preceding gene: 91789636

Following gene: 91789646

Centisome position: 76.7

GC content: 60.49

Gene sequence:

>987_bases
ATGACTCTACCTGACTTCCAACACTTTCCCAATCAGTTTTTCACCATGAAACATTCCAAAGTCCTCATCCTCGGTTCAGG
CCCTGCAGGTTATACCGCGGCGGTGTATGCAGCGCGCGCCAATCTCGACCCGGTACTGATCACCGGAATTGCGCAAGGGG
GCCAACTCATGACCACCACCGACGTGGACAACTGGCCGGCCGACGCGCAGGGCGTGCAGGGGCCGGACCTGATGCAGCGC
TTTCTCGAACATGCCGAGCGCTTCAAGACCGAGATCATCTTCGACCACATCAACCAGGTCGACCTCAGCAAGCGTCCTTT
CACGCTGACCGGTGACAGCGGCACCTACACCTGCGACACGCTGATCATCGCCACCGGTGCGTCGGCCAAATACCTCGGGC
TTGAATCCGAATCTGCGTTCATGGGTCGCGGCGTTTCCGGCTGCGCCACGTGCGATGGCTTCTTCTACCGCAACCAGGAC
GTCTGCGTGGTGGGCGGCGGCAATACGGCCGTGGAAGAGGCGTTGTACCTGTCCAACATTGCCAGCAAGGTCACGCTGGT
GCATCGCCGCGACAAATTCAAGGCCGAGGCCATCCTGATCGACAAGCTCCACGAAAAAGTGGCAGCGGGCAAGATCGAGC
TTCGCTTGCACCATACGCTGGACCAGGTGCTCGGAGACGCTTCTGGCGTGACCGGCGTGCGCCTGAAAAGCACCCTGCAT
GACACGGCGCAAGACCTGGCGCTCAAGGGTTGCTTCATCGCCATCGGCCACCAGCCCAACACGGAGATTTTTGCCGGGCA
GCTGGAAATGAAAGACGGCTACATCATCACCAAAACCGGTTTGCAGGGTTTTGCCACCATGACCAGCGTGCCGGGCGTCT
TTGCCGCCGGCGATGTGCAGGACCATGTGTACCGCCAGGCCATCACCAGCGCCGGGACCGGTTGCATGGCTGCGCTGGAT
GCCCAGCGCTTCCTGGAACAAAGCTGA

Upstream 100 bases:

>100_bases
ACCTTGCGGCGACGACAAGTCGCGCGAGTTCTTACAATGGCTTTTATCGTGAGAAAAACAAATACCGCCAAGCTTTTACC
TGCTGCAGCATTTGTTCGGC

Downstream 100 bases:

>100_bases
TACAGGGCAGCTGATTAAAAGCAGTTGATTCAGGGCTGCCGGGTTGCGGTCAGGCCACACCATAGCCCCGCTCATGCTCA
TGCTCATGGCCCGCCATTGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTLPDFQHFPNQFFTMKHSKVLILGSGPAGYTAAVYAARANLDPVLITGIAQGGQLMTTTDVDNWPADAQGVQGPDLMQR
FLEHAERFKTEIIFDHINQVDLSKRPFTLTGDSGTYTCDTLIIATGASAKYLGLESESAFMGRGVSGCATCDGFFYRNQD
VCVVGGGNTAVEEALYLSNIASKVTLVHRRDKFKAEAILIDKLHEKVAAGKIELRLHHTLDQVLGDASGVTGVRLKSTLH
DTAQDLALKGCFIAIGHQPNTEIFAGQLEMKDGYIITKTGLQGFATMTSVPGVFAAGDVQDHVYRQAITSAGTGCMAALD
AQRFLEQS

Sequences:

>Translated_328_residues
MTLPDFQHFPNQFFTMKHSKVLILGSGPAGYTAAVYAARANLDPVLITGIAQGGQLMTTTDVDNWPADAQGVQGPDLMQR
FLEHAERFKTEIIFDHINQVDLSKRPFTLTGDSGTYTCDTLIIATGASAKYLGLESESAFMGRGVSGCATCDGFFYRNQD
VCVVGGGNTAVEEALYLSNIASKVTLVHRRDKFKAEAILIDKLHEKVAAGKIELRLHHTLDQVLGDASGVTGVRLKSTLH
DTAQDLALKGCFIAIGHQPNTEIFAGQLEMKDGYIITKTGLQGFATMTSVPGVFAAGDVQDHVYRQAITSAGTGCMAALD
AQRFLEQS
>Mature_327_residues
TLPDFQHFPNQFFTMKHSKVLILGSGPAGYTAAVYAARANLDPVLITGIAQGGQLMTTTDVDNWPADAQGVQGPDLMQRF
LEHAERFKTEIIFDHINQVDLSKRPFTLTGDSGTYTCDTLIIATGASAKYLGLESESAFMGRGVSGCATCDGFFYRNQDV
CVVGGGNTAVEEALYLSNIASKVTLVHRRDKFKAEAILIDKLHEKVAAGKIELRLHHTLDQVLGDASGVTGVRLKSTLHD
TAQDLALKGCFIAIGHQPNTEIFAGQLEMKDGYIITKTGLQGFATMTSVPGVFAAGDVQDHVYRQAITSAGTGCMAALDA
QRFLEQS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=69.6485623003195, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI87081763, Length=319, Percent_Identity=30.7210031347962, Blast_Score=123, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320560, Length=322, Percent_Identity=45.9627329192547, Blast_Score=270, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6321898, Length=322, Percent_Identity=44.0993788819876, Blast_Score=263, Evalue=2e-71,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35311; Mature: 35179

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPDFQHFPNQFFTMKHSKVLILGSGPAGYTAAVYAARANLDPVLITGIAQGGQLMTTT
CCCCCHHHCCCHHEEEECCEEEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEC
DVDNWPADAQGVQGPDLMQRFLEHAERFKTEIIFDHINQVDLSKRPFTLTGDSGTYTCDT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEE
LIIATGASAKYLGLESESAFMGRGVSGCATCDGFFYRNQDVCVVGGGNTAVEEALYLSNI
EEEEECCCCEEEECCCCCHHHCCCCCCCEECCCEEEECCCEEEECCCCHHHHHHHHHHHH
ASKVTLVHRRDKFKAEAILIDKLHEKVAAGKIELRLHHTLDQVLGDASGVTGVRLKSTLH
HHHEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHCCCCCCCCEEEHHHHH
DTAQDLALKGCFIAIGHQPNTEIFAGQLEMKDGYIITKTGLQGFATMTSVPGVFAAGDVQ
HHHHHHHHCCEEEEECCCCCCCEEEEEEEECCCEEEEECCCCHHHHHHCCCCCEEECCHH
DHVYRQAITSAGTGCMAALDAQRFLEQS
HHHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLPDFQHFPNQFFTMKHSKVLILGSGPAGYTAAVYAARANLDPVLITGIAQGGQLMTTT
CCCCHHHCCCHHEEEECCEEEEEECCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEEC
DVDNWPADAQGVQGPDLMQRFLEHAERFKTEIIFDHINQVDLSKRPFTLTGDSGTYTCDT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEE
LIIATGASAKYLGLESESAFMGRGVSGCATCDGFFYRNQDVCVVGGGNTAVEEALYLSNI
EEEEECCCCEEEECCCCCHHHCCCCCCCEECCCEEEECCCEEEECCCCHHHHHHHHHHHH
ASKVTLVHRRDKFKAEAILIDKLHEKVAAGKIELRLHHTLDQVLGDASGVTGVRLKSTLH
HHHEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHCCCCCCCCEEEHHHHH
DTAQDLALKGCFIAIGHQPNTEIFAGQLEMKDGYIITKTGLQGFATMTSVPGVFAAGDVQ
HHHHHHHHCCEEEEECCCCCCCEEEEEEEECCCEEEEECCCCHHHHHHCCCCCEEECCHH
DHVYRQAITSAGTGCMAALDAQRFLEQS
HHHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]