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The map label for this gene is fabH

Identifier: 91789500

GI number: 91789500

Start: 3849620

End: 3850597

Strand: Reverse

Name: fabH

Synonym: Bpro_3650

Alternate gene names: 91789500

Gene position: 3850597-3849620 (Counterclockwise)

Preceding gene: 91789501

Following gene: 91789499

Centisome position: 74.05

GC content: 62.17

Gene sequence:

>978_bases
ATGACCCGTTATTCACGCATCACTGGCACCGGTAGTTATTTGCCACCGCGCCGACTGACCAATGCCGAGCTGGCCGCTGA
GCTGGCCACCAAGGGCGTTGAAACTTCCGACGAATGGATTGTGGAGCGCACCGGCATCCGGGCCCGCCATTTCGCCGCGC
CCGATGTGTCCAGCAGCGACCTCGCCGTGAAAGCTGCCCGGCACGCGCTGGAGGCGGCAGGCCGTCAGGCGTCCGACATT
GACCTGATCATTGTTGCGACGTCGACGCCAGACATGGTGTTTCCCTCCGCCGCGTGCATCGTGCAGAACAAACTCGGTAT
TGCGGGTTGCCCCGCCTTTGATGTCCAGGCCGTTTGCAGTGGATTTGTTTATGCACTGACCGTGGCCGACGCGTTGATCA
AAACCGGCTCGGCCACCAAGGCGCTGGTTATTGGCGCGGAAGTGTTCTCGCGCATCCTGGATTTTTCGGACAGGACCACC
TGCGTGCTGTTTGGCGATGGCGCAGGTGCCGTGGTGCTGGAAGCGTCGGAGACGCCCGGCATCCTTGCCAGCGATCTGCA
TGCTGACGGCAAGCATGTCGGCATCCTGTGCGTACCGGGCAATGTATCGGGTGGCCAGGTGCTGGGCGATCCCCTCCTCA
AAATGGACGGGCAGGCCGTGTTCAAGCTGGCCGTTGGCGTTCTTGAAAGCTCGGCCCGGGCCGCGCTGGCCAAAGCCAAC
CTGCGGGATACGGATATCGACTGGCTGATTCCGCACCAGGCCAACATCCGCATCATGCAGAGCACAGCGAAGAAGCTGAA
GGTGCCCCCGGAAAAGCTGATCGTCACGGTCGACGAGCATGGCAACACCTCGGCAGCGTCCATCCCGCTGGCGCTGGATG
CGTCCGTGCGCAGCGGCAAGGTGAAAAAAGGTGACACCCTCATGCTCGAAGGCGTGGGCGGCGGCTTTACCTGGGGTGCG
GTGCTTCTCAACTATTGA

Upstream 100 bases:

>100_bases
GTTGCTGGTTGCAGCACAGATGGCACCGGCCAGTGATGGAGTGAGTGCGGTTTCTTCGATGGCAGTTGACCCAGCAGTCT
CTACACCGGCACACTAATCA

Downstream 100 bases:

>100_bases
GAGATGACTCCATGTATTTCCCGGCCAGCTACTGACCGACAGGTGGCCGCTTGAGTCTCGGACCGTCAGGCGTGTGGATG
CCATTGCAATCCTGCTGCTG

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTRYSRITGTGSYLPPRRLTNAELAAELATKGVETSDEWIVERTGIRARHFAAPDVSSSDLAVKAARHALEAAGRQASDI
DLIIVATSTPDMVFPSAACIVQNKLGIAGCPAFDVQAVCSGFVYALTVADALIKTGSATKALVIGAEVFSRILDFSDRTT
CVLFGDGAGAVVLEASETPGILASDLHADGKHVGILCVPGNVSGGQVLGDPLLKMDGQAVFKLAVGVLESSARAALAKAN
LRDTDIDWLIPHQANIRIMQSTAKKLKVPPEKLIVTVDEHGNTSAASIPLALDASVRSGKVKKGDTLMLEGVGGGFTWGA
VLLNY

Sequences:

>Translated_325_residues
MTRYSRITGTGSYLPPRRLTNAELAAELATKGVETSDEWIVERTGIRARHFAAPDVSSSDLAVKAARHALEAAGRQASDI
DLIIVATSTPDMVFPSAACIVQNKLGIAGCPAFDVQAVCSGFVYALTVADALIKTGSATKALVIGAEVFSRILDFSDRTT
CVLFGDGAGAVVLEASETPGILASDLHADGKHVGILCVPGNVSGGQVLGDPLLKMDGQAVFKLAVGVLESSARAALAKAN
LRDTDIDWLIPHQANIRIMQSTAKKLKVPPEKLIVTVDEHGNTSAASIPLALDASVRSGKVKKGDTLMLEGVGGGFTWGA
VLLNY
>Mature_324_residues
TRYSRITGTGSYLPPRRLTNAELAAELATKGVETSDEWIVERTGIRARHFAAPDVSSSDLAVKAARHALEAAGRQASDID
LIIVATSTPDMVFPSAACIVQNKLGIAGCPAFDVQAVCSGFVYALTVADALIKTGSATKALVIGAEVFSRILDFSDRTTC
VLFGDGAGAVVLEASETPGILASDLHADGKHVGILCVPGNVSGGQVLGDPLLKMDGQAVFKLAVGVLESSARAALAKANL
RDTDIDWLIPHQANIRIMQSTAKKLKVPPEKLIVTVDEHGNTSAASIPLALDASVRSGKVKKGDTLMLEGVGGGFTWGAV
LLNY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family

Homologues:

Organism=Escherichia coli, GI1787333, Length=322, Percent_Identity=51.2422360248447, Blast_Score=326, Evalue=2e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABH_POLSJ (Q126I8)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_550452.1
- ProteinModelPortal:   Q126I8
- SMR:   Q126I8
- STRING:   Q126I8
- GeneID:   4013679
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_3650
- NMPDR:   fig|296591.1.peg.5123
- eggNOG:   COG0332
- HOGENOM:   HBG649927
- OMA:   NARILHA
- PhylomeDB:   Q126I8
- ProtClustDB:   PRK09352
- BioCyc:   PSP296591:BPRO_3650-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01815
- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038
- Gene3D:   G3DSA:3.40.47.10
- TIGRFAMs:   TIGR00747

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C; SSF53901 Thiolase-like

EC number: =2.3.1.41

Molecular weight: Translated: 33890; Mature: 33759

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 119-119 ACT_SITE 252-252 ACT_SITE 282-282

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYSRITGTGSYLPPRRLTNAELAAELATKGVETSDEWIVERTGIRARHFAAPDVSSSD
CCCCCEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCEEEECCCCCCCCH
LAVKAARHALEAAGRQASDIDLIIVATSTPDMVFPSAACIVQNKLGIAGCPAFDVQAVCS
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHEEEECCCCCCCCCCCCHHHHHH
GFVYALTVADALIKTGSATKALVIGAEVFSRILDFSDRTTCVLFGDGAGAVVLEASETPG
HHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCC
ILASDLHADGKHVGILCVPGNVSGGQVLGDPLLKMDGQAVFKLAVGVLESSARAALAKAN
EEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
LRDTDIDWLIPHQANIRIMQSTAKKLKVPPEKLIVTVDEHGNTSAASIPLALDASVRSGK
CCCCCCCEECCCCCCEEEEEHHHHHHCCCHHHEEEEECCCCCCCCEEEEEEEECCCCCCC
VKKGDTLMLEGVGGGFTWGAVLLNY
CCCCCEEEEEECCCCEEEHEEEECC
>Mature Secondary Structure 
TRYSRITGTGSYLPPRRLTNAELAAELATKGVETSDEWIVERTGIRARHFAAPDVSSSD
CCCCEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCEEEECCCCCCCCH
LAVKAARHALEAAGRQASDIDLIIVATSTPDMVFPSAACIVQNKLGIAGCPAFDVQAVCS
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHEEEECCCCCCCCCCCCHHHHHH
GFVYALTVADALIKTGSATKALVIGAEVFSRILDFSDRTTCVLFGDGAGAVVLEASETPG
HHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCC
ILASDLHADGKHVGILCVPGNVSGGQVLGDPLLKMDGQAVFKLAVGVLESSARAALAKAN
EEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
LRDTDIDWLIPHQANIRIMQSTAKKLKVPPEKLIVTVDEHGNTSAASIPLALDASVRSGK
CCCCCCCEECCCCCCEEEEEHHHHHHCCCHHHEEEEECCCCCCCCEEEEEEEECCCCCCC
VKKGDTLMLEGVGGGFTWGAVLLNY
CCCCCEEEEEECCCCEEEHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA