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The map label for this gene is era [H]

Identifier: 91789484

GI number: 91789484

Start: 3835567

End: 3836511

Strand: Reverse

Name: era [H]

Synonym: Bpro_3634

Alternate gene names: 91789484

Gene position: 3836511-3835567 (Counterclockwise)

Preceding gene: 91789485

Following gene: 91789483

Centisome position: 73.78

GC content: 60.11

Gene sequence:

>945_bases
ATGCTGGCCCAGGCCTTGTCATCGCGTGCTGCAGCGGGGGCTGTTCCAGATACTCCGCCCGTCGAAACGCAGCGCTGCGG
CCTGATTGCCATCGTCGGCAAGCCCAACGTGGGCAAATCCACCTTGCTCAACGCCCTGGTGGGCCAGAAGATCAGCATCA
CCTCGCGCAAGGCACAGACCACGCGCCACCGTATCACCGGTGTGCGCACGGTGGGCGCCACTCAATTTGTGTTTGTGGAT
ACCCCGGGTTTCCAGACCCGGCACGGCAATGCCCTGAACCGTTCGCTGAACCGCACGGTGGTGGGCGCCGTCAACGACGT
GGACCTGATTGTTTTTGTGGTGGAAGCCGGCCAGTTCAACCTGGCCGATGCCAAGGTGCTGGCCCTGTTGCCCGCAAAAA
CACCGGCCATTCTGTTGGCCAACAAGTTTGACCTGATCTACCGCCGCGCCGAGCTTGCGCCCTGGTTGCGCTCCATGCAG
GAGCGTCACAACTTTGCCGAGTTTGTGCCCATGTCCGCCAACAACGCCAAGGATATTGAACGGCTGTTCGGCATCTGCGA
GAAGTATTTGCCGGTGCAGCCCTGGATGTACCGCGCCGACGAACTGACCGACCGCAGCGACCGCTTCATGGCCGCCGAGA
TCATTCGCGAAAAACTGTTTCGCCTGACCGGCGACGAGTTGCCTTACACCTCCACGGTGATCATTGACAAGTATGAAGAA
GAGGGCAACCTGCGCAGGATTGCCGCCACCATCGTGGTAGAGCGCGATGGCCACAAGGGCATGGTGATTGGCGAGAAGGG
CGAAAAGCTCAAGCGAATTGGCACCGAGTCCCGCCATGAGCTTGAAACGCTCACCGGCAACAAGGTATTCCTGGAGATAT
GGGTCAAGGTGCGCTCGGGTTGGGCGGACGACGAAGCTCGGGTCAAGACATTCGGGTATGAATGA

Upstream 100 bases:

>100_bases
AGAGACCATGAGTACAGGTAAAAAAGAGCCGAAGAAGCCGGCGAATATATCGCTTGAATTGCCCGCTGACGAGGCGCAGG
GTCCTGACGCGCTGGATGCC

Downstream 100 bases:

>100_bases
GGCCCCCACGCTTGTCGCTTCGCGTACTGCGCTGCCCCCCGAGGGGGCCGCTGCGCCTGCGGCCCGGCGAAGCCGGTTCC
GCGGCCCCTGCTGGGAGGGG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MLAQALSSRAAAGAVPDTPPVETQRCGLIAIVGKPNVGKSTLLNALVGQKISITSRKAQTTRHRITGVRTVGATQFVFVD
TPGFQTRHGNALNRSLNRTVVGAVNDVDLIVFVVEAGQFNLADAKVLALLPAKTPAILLANKFDLIYRRAELAPWLRSMQ
ERHNFAEFVPMSANNAKDIERLFGICEKYLPVQPWMYRADELTDRSDRFMAAEIIREKLFRLTGDELPYTSTVIIDKYEE
EGNLRRIAATIVVERDGHKGMVIGEKGEKLKRIGTESRHELETLTGNKVFLEIWVKVRSGWADDEARVKTFGYE

Sequences:

>Translated_314_residues
MLAQALSSRAAAGAVPDTPPVETQRCGLIAIVGKPNVGKSTLLNALVGQKISITSRKAQTTRHRITGVRTVGATQFVFVD
TPGFQTRHGNALNRSLNRTVVGAVNDVDLIVFVVEAGQFNLADAKVLALLPAKTPAILLANKFDLIYRRAELAPWLRSMQ
ERHNFAEFVPMSANNAKDIERLFGICEKYLPVQPWMYRADELTDRSDRFMAAEIIREKLFRLTGDELPYTSTVIIDKYEE
EGNLRRIAATIVVERDGHKGMVIGEKGEKLKRIGTESRHELETLTGNKVFLEIWVKVRSGWADDEARVKTFGYE
>Mature_314_residues
MLAQALSSRAAAGAVPDTPPVETQRCGLIAIVGKPNVGKSTLLNALVGQKISITSRKAQTTRHRITGVRTVGATQFVFVD
TPGFQTRHGNALNRSLNRTVVGAVNDVDLIVFVVEAGQFNLADAKVLALLPAKTPAILLANKFDLIYRRAELAPWLRSMQ
ERHNFAEFVPMSANNAKDIERLFGICEKYLPVQPWMYRADELTDRSDRFMAAEIIREKLFRLTGDELPYTSTVIIDKYEE
EGNLRRIAATIVVERDGHKGMVIGEKGEKLKRIGTESRHELETLTGNKVFLEIWVKVRSGWADDEARVKTFGYE

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=323, Percent_Identity=28.1733746130031, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1788919, Length=296, Percent_Identity=48.6486486486487, Blast_Score=281, Evalue=4e-77,
Organism=Drosophila melanogaster, GI24646434, Length=310, Percent_Identity=26.1290322580645, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 35037; Mature: 35037

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAQALSSRAAAGAVPDTPPVETQRCGLIAIVGKPNVGKSTLLNALVGQKISITSRKAQT
CCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEECCHHHHH
TRHRITGVRTVGATQFVFVDTPGFQTRHGNALNRSLNRTVVGAVNDVDLIVFVVEAGQFN
HHHHHHEEEEECCEEEEEEECCCCCCCCCCHHHHCCCCEEEECCCCCEEEEEEEECCCCC
LADAKVLALLPAKTPAILLANKFDLIYRRAELAPWLRSMQERHNFAEFVPMSANNAKDIE
CCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHH
RLFGICEKYLPVQPWMYRADELTDRSDRFMAAEIIREKLFRLTGDELPYTSTVIIDKYEE
HHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECC
EGNLRRIAATIVVERDGHKGMVIGEKGEKLKRIGTESRHELETLTGNKVFLEIWVKVRSG
CCCEEEEEEEEEEEECCCCCEEECCCCHHHHHCCCCCHHHHHHHCCCEEEEEEEEEHHCC
WADDEARVKTFGYE
CCCCCCCEEECCCC
>Mature Secondary Structure
MLAQALSSRAAAGAVPDTPPVETQRCGLIAIVGKPNVGKSTLLNALVGQKISITSRKAQT
CCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEECCHHHHH
TRHRITGVRTVGATQFVFVDTPGFQTRHGNALNRSLNRTVVGAVNDVDLIVFVVEAGQFN
HHHHHHEEEEECCEEEEEEECCCCCCCCCCHHHHCCCCEEEECCCCCEEEEEEEECCCCC
LADAKVLALLPAKTPAILLANKFDLIYRRAELAPWLRSMQERHNFAEFVPMSANNAKDIE
CCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHH
RLFGICEKYLPVQPWMYRADELTDRSDRFMAAEIIREKLFRLTGDELPYTSTVIIDKYEE
HHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECC
EGNLRRIAATIVVERDGHKGMVIGEKGEKLKRIGTESRHELETLTGNKVFLEIWVKVRSG
CCCEEEEEEEEEEEECCCCCEEECCCCHHHHHCCCCCHHHHHHHCCCEEEEEEEEEHHCC
WADDEARVKTFGYE
CCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]