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The map label for this gene is acpS

Identifier: 91789481

GI number: 91789481

Start: 3833434

End: 3833832

Strand: Reverse

Name: acpS

Synonym: Bpro_3631

Alternate gene names: 91789481

Gene position: 3833832-3833434 (Counterclockwise)

Preceding gene: 91789482

Following gene: 91789480

Centisome position: 73.72

GC content: 61.15

Gene sequence:

>399_bases
ATGATTTACGGCGTGGGTACCGACATCTGCGACGTGCGCCGCATCCGCGCCAGCCTGGAGCGTCATGGCGAGCGCTTGGC
CCAAAAAATCCTCAGCGAAGCCGAGCTGGCCACGTGGAAGGAGCGCAGCGAGCGCTGGCCGGATCGCGGCGTGCGCTACC
TGGCCACGCGGTTTTCAGCCAAAGAGGCTTTCAGCAAGGCGATTGGGCTGGGCATGCGCATGCCCATGACCTGGCGCCAT
TGCGAAATTTCCAAAGCGGCCAGCGGCAAGCCCGAGATTGTGCTGCACGGTCCGCTCAAGGACTGGTTTGAGACCCGCCA
ACTGAGTGTGCATGTCAGCGTGACCGATGAGAACGAGTATGCGGCCAGCTTTTGCGTCGTAGAGAAAAACGACTTCTAG

Upstream 100 bases:

>100_bases
TCGGCCACGCCCTGATAGCCGACGCGCTGGAGCTGGGCTATACCGCGACCGTGAAAGATTACCTGCGCCGTATTGACGAA
GCCTTTGCCGTGACGACCTG

Downstream 100 bases:

>100_bases
CTATGCGATATTTGAGTAGGCAGCTATCAATTAAATAGCAACCCTGAAGTGGTAACCTTGAAATATTTCCCATGACCCAG
CACGCTCCCCTGATCATCGA

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MIYGVGTDICDVRRIRASLERHGERLAQKILSEAELATWKERSERWPDRGVRYLATRFSAKEAFSKAIGLGMRMPMTWRH
CEISKAASGKPEIVLHGPLKDWFETRQLSVHVSVTDENEYAASFCVVEKNDF

Sequences:

>Translated_132_residues
MIYGVGTDICDVRRIRASLERHGERLAQKILSEAELATWKERSERWPDRGVRYLATRFSAKEAFSKAIGLGMRMPMTWRH
CEISKAASGKPEIVLHGPLKDWFETRQLSVHVSVTDENEYAASFCVVEKNDF
>Mature_132_residues
MIYGVGTDICDVRRIRASLERHGERLAQKILSEAELATWKERSERWPDRGVRYLATRFSAKEAFSKAIGLGMRMPMTWRH
CEISKAASGKPEIVLHGPLKDWFETRQLSVHVSVTDENEYAASFCVVEKNDF

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=39.0625, Blast_Score=85, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_POLSJ (Q126K7)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_550433.1
- ProteinModelPortal:   Q126K7
- SMR:   Q126K7
- STRING:   Q126K7
- GeneID:   4013699
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_3631
- NMPDR:   fig|296591.1.peg.5140
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   Q126K7
- ProtClustDB:   PRK00070
- BioCyc:   PSP296591:BPRO_3631-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 15158; Mature: 15158

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGVGTDICDVRRIRASLERHGERLAQKILSEAELATWKERSERWPDRGVRYLATRFSA
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KEAFSKAIGLGMRMPMTWRHCEISKAASGKPEIVLHGPLKDWFETRQLSVHVSVTDENEY
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHCCEEEEEEEEECCCCC
AASFCVVEKNDF
EEEEEEEECCCC
>Mature Secondary Structure
MIYGVGTDICDVRRIRASLERHGERLAQKILSEAELATWKERSERWPDRGVRYLATRFSA
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KEAFSKAIGLGMRMPMTWRHCEISKAASGKPEIVLHGPLKDWFETRQLSVHVSVTDENEY
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHCCEEEEEEEEECCCCC
AASFCVVEKNDF
EEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA